Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair

Stem Cells

Volumn 28, Issue 11, 2010, Pages 2088-2098

  Li, Tao Sheng ^a   Cheng, Ke ^a   Lee, Shuo Tsan ^a   Matsushita, Satoshi ^a   Davis, Darryl ^a   Malliaras, Konstantinos ^a   Zhang, Yiqiang ^a   Matsushita, Noriko ^a   Smith, Rachel Ruckdeschel ^a   Marbán, Eduardo ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Adhesion molecule; Cardiac stem cells; Extracellular matrix molecules; Stem cell niche

Indexed keywords

ALPHA2 INTEGRIN; HISTONE DEACETYLASE 2; LAMININ; LAMININ BETA1; MATRIX METALLOPROTEINASE; SCLEROPROTEIN; SOMATOMEDIN C; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ACUTE HEART INFARCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL GROWTH; CELL INTERACTION; CELL SURVIVAL; CELL TRANSPLANTATION; CLINICAL ARTICLE; CONTROLLED STUDY; ENGRAFTMENT; EXTRACELLULAR MATRIX; HEART FUNCTION; HEART MUSCLE; HEART MUSCLE BIOPSY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROENVIRONMENT; MONOLAYER CULTURE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SCID MOUSE; STEM CELL; SUSPENSION CELL CULTURE; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; ECHOCARDIOGRAPHY; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; HISTONE DEACETYLASE 2; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTEGRIN ALPHA2; LAMININ; MICE; MICE, SCID; MYOCARDIAL INFARCTION; MYOCARDIUM; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; STEM CELL TRANSPLANTATION; STEM CELLS; TELOMERASE;

EID: 78649835433     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.532     Document Type: Article

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