IGF-1-overexpressing mesenchymal stem cells accelerate bone marrow stem cell mobilization via paracrine activation of SDF-1α/CXCR4 signaling to promote myocardial repair

Circulation Research

Volumn 103, Issue 11, 2008, Pages 1300-1308

  Haider, Husnain Kh ^a   Jiang, Shujia ^a   Idris, Niagara M ^a   Ashraf, Muhammad ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Heart; IGF 1; Myocardial infarction; SDF 1; Stem cells

Indexed keywords

ACTININ; ADENOVIRUS VECTOR; CHEMOKINE RECEPTOR CXCR4; CONNEXIN 43; GLYCOGEN SYNTHASE KINASE 3BETA; MYOSIN HEAVY CHAIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL XL; PROTEIN KINASE B BETA; SOMATOMEDIN C; STROMAL CELL DERIVED FACTOR 1ALPHA; VON WILLEBRAND FACTOR; CXCL12 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN; GROWTH PROMOTOR; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL HOMING; CELL SURVIVAL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENGRAFTMENT; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION; GENETIC TRANSDUCTION; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEMATOPOIETIC STEM CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMPLANTATION; IN VIVO STUDY; MESENCHYMAL STEM CELL; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STEM CELL MOBILIZATION; TRANSGENE; ANIMAL; BONE MARROW CELL; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; HEART; HUMAN; METHODOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC RAT; WOUND HEALING;

ANIMALS; BONE MARROW CELLS; CELL SURVIVAL; CHEMOKINE CXCL12; GENE EXPRESSION REGULATION; GROWTH SUBSTANCES; HEART; HEMATOPOIETIC STEM CELL MOBILIZATION; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MESENCHYMAL STEM CELLS; MYOCARDIAL INFARCTION; RATS; RATS, TRANSGENIC; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 58149345104     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.186742     Document Type: Article

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