Factors released from embryonic stem cells stimulate c-kit-FLK-1 +ve progenitor cells and enhance neovascularization

Antioxidants and Redox Signaling

Volumn 13, Issue 12, 2010, Pages 1857-1865

  Fatma, Sumbul ^a   Selby, Donald E ^b   Singla, Reetu D ^a   Singla, Dinender K ^a  

^a UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CD31 ANTIGEN; SCATTER FACTOR; SOMATOMEDIN BINDING PROTEIN 1; STEM CELL FACTOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CELL STIMULATION; CONTROLLED STUDY; CORONARY ARTERY; CORONARY BLOOD VESSEL; CULTURE MEDIUM; EMBRYO; EMBRYONIC STEM CELL; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; HEART FUNCTION; HEART INFARCTION; HEART TRANSPLANTATION; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD31; APOPTOSIS; CASPASE 3; CULTURE MEDIA, CONDITIONED; ECHOCARDIOGRAPHY; EMBRYONIC STEM CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IN SITU NICK-END LABELING; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MYOCARDIAL INFARCTION; NEOVASCULARIZATION, PHYSIOLOGIC; PROTO-ONCOGENE PROTEINS C-KIT; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 78149334458     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2010.3104     Document Type: Article

References (37)

1. Anversa P, Cheng W, Liu Y, Leri A, Redaelli G, and Kajstura J. Apoptosis and myocardial infarction. Basic Res Cardiol 93 Suppl 3: 8-12, 1998.
2. Anversa P, Kajstura J, and Olivetti G. Myocyte death in heart failure. Curr Opin Cardiol 11: 245-251, 1996.
3. Anversa P, Leri A, Kajstura J, and Nadal-Ginard B. Myocyte growth and cardiac repair. J Mol Cell Cardiol 34: 91-105, 2002.
4. Anversa P, Olivetti G, Leri A, Liu Y, and Kajstura J. Myocyte cell death and ventricular remodeling. Curr Opin Nephrol Hypertens 6: 169-176, 1997.
5. Borselli C, Storrie H, Benesch-Lee F, Shvartsman D, Cezar C, Lichtman JW, Vandenburgh HH, and Mooney DJ. Functional muscle regeneration with combined delivery of angiogenesis and myogenesis factors 1. Proc Natl Acad Sci USA 107: 3287-3292, 2010.
6. Elmarakby AA, Loomis ED, Pollock JS, and Pollock DM. NADPH oxidase inhibition attenuates oxidative stress but not hypertension produced by chronic ET-1 1. Hypertension 45: 283-287, 2005.
7. Gnecchi M, He H, Liang OD, Melo LG, Morello F, Mu H, Noiseux N, Zhang L, Pratt RE, Ingwall JS, and Dzau VJ. Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells. Nat Med 11: 367-368, 2005.
8. Gnecchi M, He H, Noiseux N, Liang OD, Zhang L, Morello F, Mu H, Melo LG, Pratt RE, Ingwall JS, and Dzau VJ. Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement. FASEB J 20: 661-669, 2006.
9. Griese DP, Ehsan A, Melo LG, Kong D, Zhang L, Mann MJ, Pratt RE, Mulligan RC, and Dzau VJ. Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: Implications for cell-based vascular therapy 2. Circulation 108: 2710-2715, 2003.
10. Haider HK and Ashraf M. Bone marrow cell transplantation in clinical perspective. J Mol Cell Cardiol 38: 225-235, 2005. (Pubitemid 40215191)
11. Haider HK and Ashraf M. Bone marrow stem cell transplantation for cardiac repair. Am J Physiol Heart Circ Physiol 288: H2557-H2567, 2005. (Pubitemid 40720630)
12. Jujo K, Ii M, and Losordo DW. Endothelial progenitor cells in neovascularization of infarcted myocardium. J Mol Cell Cardiol 45: 530-544, 2008.
13. Kong D, Melo LG, Gnecchi M, Zhang L, Mostoslavsky G, Liew CC, Pratt RE, and Dzau VJ. Cytokine-induced mobilization of circulating endothelial progenitor cells enhances repair of injured arteries 2. Circulation 110: 2039-2046, 2004.
14. Koracevic D, Koracevic G, Djordjevic V, Andrejevic S, and Cosic V. Method for the measurement of antioxidant activity in human fluids 1. J Clin Pathol 54: 356-361, 2001.
15. Kudo M, Wang Y, Wani MA, Xu M, Ayub A, and Ashraf M. Implantation of bone marrow stem cells reduces the infarction and fibrosis in ischemic mouse heart. J Mol Cell Cardiol 35: 1113-1119, 2003.
16. Kumar D, Hacker TA, Buck J, Whitesell LF, Kaji EH, Douglas PS, and Kamp TJ. Distinct mouse coronary anatomy and myocardial infarction consequent to ligation. Coron Artery Dis 16: 41-44, 2005.
17. Kumar D and Jugdutt BI. Apoptosis and oxidants in the heart. J Lab Clin Med 142: 288-297, 2003.
18. Kumar D, Kamp TJ, and LeWinter MM. Embryonic stem cells: Differentiation into cardiomyocytes and potential for heart repair and regeneration. Coron Artery Dis 16: 111-116, 2005.
19. Kumar D, Lou H, and Singal PK. Oxidative stress and ap-optosis in heart dysfunction. Herz 27: 662-668, 2002.
20. Levenberg S, Zoldan J, Basevitch Y, and Langer R. En-dothelial potential of human embryonic stem cells. Blood 110: 806-814, 2007. (Pubitemid 47267415)
21. Li Q, Li B, Wang X, Leri A, Jana KP, Liu Y, Kajstura J, Baserga R, and Anversa P. Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J Clin Invest 100: 1991-1999, 1997.
22. Loomans CJ, Wan H, de CR, van HR, de Boer HC, Leenen PJ, Drexhage HA, Rabelink TJ, van Zonneveld AJ, and Staal FJ. Angiogenic murine endothelial progenitor cells are derived from a myeloid bone marrow fraction and can be identified by endothelial NO synthase expression. Arter-ioscler Thromb Vasc Biol 26: 1760-1767, 2006.
23. Min JY, Yang Y, Converso KL, Liu L, Huang Q, Morgan JP, and Xiao YF. Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats. J Appl Physiol 92: 288-296, 2002.
24. Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F, Nadal-Ginard B, Bodine DM, Leri A, and Anversa P. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA 98: 10344-10349, 2001.
25. Ripa RS, Jorgensen E, Wang Y, Thune JJ, Nilsson JC, Son-dergaard L, Johnsen HE, Kober L, Grande P, and Kastrup J. Stem cell mobilization induced by subcutaneous granulo-cyte-colony stimulating factor to improve cardiac regeneration after acute ST-elevation myocardial infarction: Result of the double-blind, randomized, placebo-controlled stem cells in myocardial infarction (STEMMI) trial. Circulation 113: 1983-1992, 2006.
26. Sieveking DP and Ng MK. Cell therapies for therapeutic angiogenesis: Back to the bench. Vasc Med 14: 153-166, 2009.
27. Singla DK. Embryonic stem cells in cardiac repair and regeneration. Antioxid Redox Signal 11: 1857-1863, 2009.
28. Singla DK, Hacker TA, Ma L, Douglas PS, Sullivan R, Lyons GE, and Kamp TJ. Transplantation of embryonic stem cells into the infarcted mouse heart: Formation of multiple cell types. J Mol Cell Cardiol 40: 195-200, 2006.
29. Singla DK, Lyons GE, and Kamp TJ. Transplanted embryonic stem cells following mouse myocardial infarction inhibit apoptosis and cardiac remodeling. Am J Physiol Heart Circ Physiol 293: H1308-H1314, 2007.
30. Singla DK and McDonald DE. Factors released from embryonic stem cells inhibit apoptosis of H9c2 cells. Am J Physiol Heart Circ Physiol 293: H1590-H1595, 2007.
31. Singla DK, Singla RD, and McDonald DE. Factors released from embryonic stem cells inhibit apoptosis in H9c2 cells through P1-3kinase/Akt but not ERK pathway. Am J Physiol Heart Circ Physiol 295: H907-913, 2008.
32. Tillmanns J, Rota M, Hosoda T, Misao Y, Esposito G, Gonzalez A, Vitale S, Parolin C, Yasuzawa-Amano S, Muraski J, De AA, Lecapitaine N, Siggins RW, Loredo M, Bearzi C, Bolli R, Urbanek K, Leri A, Kajstura J, and Anversa P. Formation of large coronary arteries by cardiac progenitor cells. Proc Natl Acad Sci USA 105: 1668-1673, 2008.
33. Wang Y, Ahmad N, Wani MA, and Ashraf M. Hepatocyte growth factor prevents ventricular remodeling and dysfunction in mice via Akt pathway and angiogenesis. J Mol Cell Cardiol 37: 1041-1052, 2004.
34. Werner N, Priller J, Laufs U, Endres M, Bohm M, Dirnagl U, and Nickenig G. Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: Effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition 3. Arterioscler Thromb Vasc Biol 22: 1567-1572, 2002.
35. Yamahara K and Itoh H. Potential use of endothelial progenitor cells for regeneration of the vasculature. Ther Adv Cardiovasc Dis 3: 17-27, 2009.
36. Yamashita J, Itoh H, Hirashima M, Ogawa M, Nishikawa S, Yurugi T, Naito M, Nakao K, and Nishikawa S. Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature 408: 92-96, 2000.
37. Zohlnhofer D, Ott I, Mehilli J, Schomig K, Michalk F, Ibrahim T, Meisetschlager G, von WJ, Bollwein H, Seyfarth M, Dirschinger J, Schmitt C, Schwaiger M, Kastrati A, and Schomig A. Stem cell mobilization by granulocyte colony-stimulating factor in patients with acute myocardial infarction: A randomized controlled trial. JAMA 295: 1003-1010, 2006.