Hidden in plain sight: Subtle effects of the 8-oxoguanine lesion on the structure, dynamics, and thermodynamics of a 15-base pair oligodeoxynucleotide duplex

Biochemistry

Volumn 50, Issue 39, 2011, Pages 8463-8477

  Crenshaw, Charisse M ^b   Wade, Jacqueline E ^a   Arthanari, Haribabu ^c   Frueh, Dominique ^d   Lane, Benjamin F ^e   Núñez, Megan E ^a  

^a MOUNT HOLYOKE COLLEGE   (United States)

^b HARVARD UNIVERSITY   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e CHARLES STARK DRAPER LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8-OXOGUANINE; APPARENT EQUILIBRIUM CONSTANT; BASE EXCISION REPAIRS; BASE PAIRS; DUPLEX STRUCTURES; GUANINE CYTOSINES; NUCLEAR OVERHAUSER EFFECTS; OLIGODEOXYNUCLEOTIDES; PHOTOCLEAVAGES;

DICHROISM; EQUILIBRIUM CONSTANTS; EXPERIMENTS; MAGNETIC RESONANCE SPECTROSCOPY; OLIGONUCLEOTIDES; POSITIVE IONS; RHODIUM; SUGARS; THERMODYNAMICS;

CIRCULAR DICHROISM SPECTROSCOPY;

8 HYDROXYGUANINE; CYTOSINE; DOUBLE STRANDED DNA; OLIGODEOXYNUCLEOTIDE; RHODIUM; SUGAR;

ARTICLE; BASE MISPAIRING; BASE PAIRING; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; CONTROLLED STUDY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN CLEAVAGE; THERMODYNAMICS; ULTRAVIOLET RADIATION;

BASE PAIRING; BASE SEQUENCE; DNA DAMAGE; DNA REPAIR; GUANINE; MAGNETIC RESONANCE SPECTROSCOPY; OLIGODEOXYRIBONUCLEOTIDES; THERMODYNAMICS;

EID: 80053405018     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201007t     Document Type: Article

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