Search for α-helical propensity in the receptor-bound conformation of glucagon-like peptide-1

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 23, 2008, Pages 10106-10112

  Murage, Eunice N ^a   Schroeder, Jonathan C ^b   Beinborn, Martin ^b   Ahn, Jung Mo ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b TUFTS MEDICAL CENTER   (United States)

Author keywords

Alpha helical propensity; Bicyclic GLP 1 analogue; Cyclic peptides containing lactam bridges; Glucagon like peptide 1; Receptor bound conformation

Indexed keywords

DISULFIDE; GLUCAGON LIKE PEPTIDE 1; GLUTAMINE; GLYCINE; LACTAM; LYSINE; THREONINE;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; MOLECULAR WEIGHT; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN SYNTHESIS; RECEPTOR BINDING;

AMINO ACID SEQUENCE; CELLS, CULTURED; CIRCULAR DICHROISM; GLUCAGON-LIKE PEPTIDE 1; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; RECEPTORS, GLUCAGON; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 55749095379     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.10.006     Document Type: Article

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