The isolated N-terminal domain of the glucagon-like peptide-1 (GLP-1) receptor binds exendin peptides with much higher affinity than GLP-1

Journal of Biological Chemistry

Volumn 278, Issue 12, 2003, Pages 10195-10200

  De Maturana, Rakel López ^a   Willshaw, Angela ^a   Kuntzsch, Antje ^b   Rudolph, Rainer ^b   Donnelly, Dan ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CELL MEMBRANES; CELLS; PROTEINS;

MAMMALIAN CELLS;

BIOCHEMISTRY;

EXENDIN; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; PEPTIDE DERIVATIVE; POLYHISTIDINE; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; GLUCAGON; GLUCAGON LIKE PEPTIDE RECEPTOR; GLUCAGON RECEPTOR; GLUCAGON-LIKE PEPTIDE RECEPTOR; PEPTIDE; PEPTIDE FRAGMENT; PROTEIN PRECURSOR; RECOMBINANT PROTEIN; VENOM;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CARBOXY TERMINAL SEQUENCE; ESCHERICHIA COLI; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; RECEPTOR BINDING; AMINO ACID SEQUENCE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MOLECULAR GENETICS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA;

AMINO ACID SEQUENCE; BINDING, COMPETITIVE; CELL LINE; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDES; PROTEIN PRECURSORS; RECEPTORS, GLUCAGON; RECOMBINANT PROTEINS; VENOMS;

EID: 0037518197     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212147200     Document Type: Article

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