Spatial Approximation between the Amino Terminus of a Peptide Agonist and the Top of the Sixth Transmembrane Segment of the Secretin Receptor

Journal of Biological Chemistry

Volumn 279, Issue 4, 2004, Pages 2894-2903

  Dong, Maoqing ^a   Li, Zhijun ^b   Pinon, Delia I ^a   Lybrand, Terry P ^b   Miller, Laurence J ^a  

^a MAYO CLINIC   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL MEMBRANES; CHEMICAL ACTIVATION; CONFORMATIONS; HORMONES; SPATIAL VARIABLES MEASUREMENT;

BIOCHEMICAL RECEPTORS;

AMINES;

CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; SECRETIN; SECRETIN RECEPTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHO CELL; CONFORMATIONAL TRANSITION; COVALENT BOND; DISULFIDE BOND; DRUG TARGETING; LIGAND BINDING; NONHUMAN; PEPTIDE ANALYSIS; PHARMACOPHORE; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PHOTOAFFINITY LABELS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, GASTROINTESTINAL HORMONE; SECRETIN;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 1642494670     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310407200     Document Type: Article

References (48)

1. Qi, L. J., Leung, A. T., Xiong, Y., Marx, K. A., and Abou-Samra, A. B. (1997) Biochemistry 36, 12442-12448
2. Perrin, M. H., Fischer, W. H., Kunitake, K. S., Craig, A. G., Koerber, S. C., Cervini, L. A., Rivier, J. E., Groppe, J. C., Greenwald, J., Moller, N. S., and Vale, W. W. (2001) J. Biol. Chem. 276, 31528-31534
3. Grauschopf, U., Lilie, H., Honold, K., Wozny, M., Reusch, D., Esswein, A., Schafer, W., Rucknagel, K. P., and Rudolph, R. (2000) Biochemistry 39, 8878-8887
4. Bazarsuren, A., Grauschopf, U., Wozny, M., Reusch, D., Hoffmann, E., Schaefer, W., Panzner, S., and Rudolph, R. (2002) Biophys. Chem. 96, 305-318
5. Asmann, Y. W., Dong, M., Ganguli, S., Hadac, E. M., and Miller, L. J. (2000) Mol. Pharmacol. 58, 911-919
6. Holtmann, M. H., Hadac, E. M., and Miller, L. J. (1995) J. Biol. Chem. 270, 14394-14398
7. Holtmann, M. H., Ganguli, S., Hadac, E. M., Dolu, V., and Miller, L. J. (1996) J. Biol. Chem. 271, 14944-14949
8. Dong, M., Wang, Y., Pinon, D. I., Hadac, E. M., and Miller, L. J. (1999) J. Biol. Chem. 274, 903-909
9. Dong, M., Wang, Y., Hadac, E. M., Pinon, D. I., Holicky, E., and Miller, L. J. (1999) J. Biol. Chem. 274, 19161-19167
10. Dong, M., Asmann, Y. W., Zang, M., Pinon, D. I., and Miller, L. J. (2000) J. Biol. Chem. 275, 26032-26039
11. Dong, M., Zang, M. W., Pinon, D. I., Li, Z., Lybrand, T. P., and Miller, L. J. (2002) Mol. Endocrinol. 16, 2490-2501
12. Zang, M., Dong, M., Pinon, D. I., Ding, X. Q., Hadac, E. M., Li, Z., Lybrand, T. P., and Miller, L. J. (2003) Mol. Pharmacol. 63, 993-1001
13. Dong, M., Li, Z., Zang, M., Pinon, D. I., Lybrand, T. P., and Miller, L. J. (2003) J. Biol. Chem. 278, 48300-48312
14. Bisello, A., Adams, A. E., Mierke, D. F., Pellegrini, M., Rosenblatt, M., Suva, L. J., and Chorev, M. (1998) J. Biol. Chem. 273, 22498-22505
15. Behar, V., Bisello, A., Bitan, G., Rosenblatt, M., and Chorev, M. (2000) J. Biol. Chem. 275, 9-17
16. Hefford, M. A., and Kaplan, H. (1989) Biochim. Biophys. Acta 998, 267-270
17. Pearson, R. K., Miller, L. J., Hadac, E. M., and Powers, S. P. (1987) J. Biol. Chem. 262, 13850-13856
18. Powers, S. O., Pinon, D. I., and Miller, L. J. (1988) Int. J. Pept. Protein Res. 31, 429-434
19. Ulrich, C. D., Pinon, D. I., Hadac, E. M., Holicky, E. L., Chang-Miller, A., Gates, L. K., and Miller, L. J. (1993) Gastroenterology 105, 1534-1543
20. Sanger, F., Nicklen, S., and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U. S. A. 74, 5463-5467
21. Hadac, E. M., Ghanekar, D. V., Holicky, E. L., Pinon, D. I., Dougherty, R. W., and Miller, L. J. (1996) Pancreas 13, 130-139
22. Ganguli, S. C., Park, C. G., Holtmann, M. H., Hadac, E. M., Kenakin, T. P., and Miller, L. J. (1998) J. Pharmacol. Exp. Ther. 286, 593-598
23. Laemmli, U. K. (1970) Nature 227, 680-685
24. Ji, Z., Hadac, E. M., Henne, R. M., Patel, S. A., Lybrand, T. P., and Miller, L. J. (1997) J. Biol. Chem. 272, 24393-24401
25. Hadac, E. M., Pinon, D. I., Ji, Z., Holicky, E. L., Henne, R. M., Lybrand, T. P., and Miller, L. J. (1998) J. Biol. Chem. 273, 12988-12993
26. Munson, P. J., and Rodbard, D. (1980) Anal. Biochem. 107, 220-239
27. Pellegrini, M., Bisello, A., Rosenblatt, M., Chorev, M., and Mierke, D. F. (1998) Biochemistry 37, 12737-12743
28. Pearson, W. R., and Lipman, D. J. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 2444-2448
29. Chemical Computing Group, Inc. (1997-2001) MOE 2001.01, Chemical Computing Group, Inc., Montreal, Canada
30. Sali, A., and Blundell, T. L. (1993) J. Mol. Biol. 234, 779-815
31. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
32. Gregoret, L. M., and Cohen, F. E. (1990) J. Mol. Biol. 211, 959-974
33. Frimurer, T. M., and Bywater, R. P. (1999) Proteins 35, 375-386
34. Tripos, Inc. (2003) Sybyl 6.9, Tripos, Inc., St. Louis, MO
35. Clore, G. M., Nilges, M., Brunger, A., and Gronenborn, A. M. (1988) Eur. J. Biochem. 171, 479-484
36. Case, D. A., Pearlman, D. A., Caldwell, J. W., Cheatham, T. E., Wang, J., Ross, W. S., Simmerling, C., Darden, T., Merz, K. M., Stanton, R. V., Cheng, A., Vincent, J. J., Crowley, M., Tsui, V., Gohlke, H., Radmer, R., Duan, Y., Pitera, J., Massova, I., Seibel, G. L., Singh, U. C., Weiner, P., and Kollman, P. A. (2002) Amber 7, University of California, San Francisco
37. Swanson, E. (1995) PSSHOW, 4D Version, Silicon Graphics, Seattle, WA.
38. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950
39. Vilardaga, J. P., Di Paolo, E., De Neef, P., Waelbroeck, M., Bollen, A., and Robberecht, P. (1996) Biochem. Biophys. Res. Commun. 218, 842-846
40. Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Le Trong, I., Teller, D. C., Okada, T., Stenkamp, R. E., Yamamoto, M., and Miyano, M. (2000) Science 289, 739-745
41. Donnelly, D. (1997) FEBS Lett. 409, 431-436
42. Horn, F., Bywater, R., Krause, G., Kuipers, W., Oliveira, L., Paiva, A. C. M., Sander, C., and Vriend, G. (1998) Recept. Channels 5, 305-314
43. Lee, C. W., Luck, M. D., Jüppner, H., Potts, J. T., Jr., Kronenberg, H. M., and Gardella, T. J. (1995) Mol. Endocrinol. 9, 1269-1278
44. Gardella, T. J., Jüppner, H., Wilson, A. K., Keutmann, H. T., Abou-Samra, A.-B., Segre, G. V., Bringhurst, F. R., Potts, J. T., Jr., Nussbaum, S. R., and Kronenberg, H. M. (1994) Endocrinology 135, 1186-1194
45. Spalding, T. A., Burstein, E. S., Wells, J. W., and Brann, M. R. (1997) Biochemistry 36, 10109-10116
46. Konopka, J. B., Margarit, S. M., and Dube, P. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 6764-6769
47. Behar, V., Bisello, A., Rosenblatt, M., and Chorev, M. (1999) Endocrinology 140, 4251-4261
48. Mannstadt, M., Jüppner, H., and Gardella, T. J. (1999) Am. J. Physiol. 277, F665-F675