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Volumn 3 S, Issue 3, 2011, Pages 1101-1118

P2 receptor expression, signaling and function in osteoclasts

Author keywords

Apoptosis; ATP; Bone; Calcium; Calciumactivated potassium channels; Electrophysiology; Ion channel; NF B; Nucleotide; Osteoclastogenesis; Osteoclasts; P2 receptors; P2X receptors; P2X7; P2Y receptors; Patch clamp; Protein kinase C; Purinergic; Resorption; Review; Signaling; Survival

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; CALCIUM; ENHANCED GREEN FLUORESCENT PROTEIN; FLUORESCENT DYE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PURINERGIC P2 RECEPTOR; PURINERGIC P2X RECEPTOR; PURINERGIC P2X2 RECEPTOR; PURINERGIC P2X4 RECEPTOR; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y2 RECEPTOR; PURINERGIC P2Y6 RECEPTOR; URIDINE DIPHOSPHATE; URIDINE TRIPHOSPHATE;

EID: 80053125171     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (26)

References (92)
  • 1
    • 0034284970 scopus 로고    scopus 로고
    • Bone resorption by osteoclasts
    • S. L. Teitelbaum: Bone resorption by osteoclasts. Science 289, 1504-1508 (2000)
    • (2000) Science , vol.289 , pp. 1504-1508
    • Teitelbaum, S.L.1
  • 2
    • 70349577508 scopus 로고    scopus 로고
    • RANKL/RANK as key factors for osteoclast development and bone loss in arthropathies
    • Leibbrandt and J. M. Penninger: RANKL/RANK as key factors for osteoclast development and bone loss in arthropathies. Adv Exp Med Biol 649, 100-113 (2009)
    • (2009) Adv Exp Med Biol , vol.649 , pp. 100-113
    • Leibbrandt1    Penninger, J.M.2
  • 3
    • 0031765480 scopus 로고    scopus 로고
    • A combination of osteoclast differentiation factor and macrophage- colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro
    • J. M. Quinn, J. Elliott, M. T. Gillespie and T. J. Martin: A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro. Endocrinology 139, 4424-4427 (1998) (Pubitemid 28513734)
    • (1998) Endocrinology , vol.139 , Issue.10 , pp. 4424-4427
    • Quinn, J.M.W.1    Elliott, J.2    Gillespie, M.T.3    Martin, T.J.4
  • 6
    • 0020043385 scopus 로고
    • Calcitonin alters behaviour of isolated osteoclasts
    • T. J. Chambers and C. J. Magnus: Calcitonin alters behaviour of isolated osteoclasts. J Pathol 136, 27-39 (1982) (Pubitemid 12213616)
    • (1982) Journal of Pathology , vol.136 , Issue.1 , pp. 27-39
    • Chambers, T.J.1    Magnus, C.J.2
  • 7
    • 0031980097 scopus 로고    scopus 로고
    • Wortmannin inhibits spreading and chemotaxis of rat osteoclasts in vitro
    • DOI 10.1359/jbmr.1998.13.4.688
    • M. F. Pilkington, S. M. Sims and S. J. Dixon: Wortmannin inhibitsspreading and chemotaxis of rat osteoclasts in vitro. J Bone Miner Res 13, 688-694 (1998) (Pubitemid 28163020)
    • (1998) Journal of Bone and Mineral Research , vol.13 , Issue.4 , pp. 688-694
    • Pilkington, M.F.1    Sims, S.M.2    Dixon, S.J.3
  • 8
    • 0036797058 scopus 로고    scopus 로고
    • Osteoclast spreading kinetics are correlated with an oscillatory activation of a calcium-dependent potassium current
    • DOI 10.1242/jcs.00062
    • L. Espinosa, L. Paret, C. Ojeda, Y. Tourneur, P. D. Delmas and C. Chenu: Osteoclast spreadingkinetics are correlated with an oscillatory activation of a calciumdependent potassium current. J Cell Sci 115, 3837-3848 (2002) (Pubitemid 35203610)
    • (2002) Journal of Cell Science , vol.115 , Issue.19 , pp. 3837-3848
    • Espinosa, L.1    Paret, L.2    Ojeda, C.3    Tourneur, Y.4    Delmas, P.D.5    Chenu, C.6
  • 9
    • 6344231716 scopus 로고    scopus 로고
    • Guiding cell migration through directed extension and stabilization of pseudopodia
    • DOI 10.1016/j.yexcr.2004.08.006, PII S0014482704004549
    • D. Chodniewicz and R. L. Klemke: Guiding cell migration through directed extension and stabilization of pseudopodia. Exp Cell Res 301, 31-37 (2004) (Pubitemid 39388893)
    • (2004) Experimental Cell Research , vol.301 , Issue.1 , pp. 31-37
    • Chodniewicz, D.1    Klemke, R.L.2
  • 10
    • 0024778752 scopus 로고
    • Beta3 subunit of vitronectin receptor is present in osteoclast adhesion structures and not in other monocytemacrophage derived cells
    • Zambonin Zallone, A. Teti, M. Gaboli and P. C. Marchisio: Beta3 subunit of vitronectin receptor is present in osteoclast adhesion structures and not in other monocytemacrophage derived cells. Connect Tissue Res 20, 143-149 (1989)
    • (1989) Connect Tissue Res , vol.20 , pp. 143-149
    • Zallone, Z.1    Teti, A.2    Gaboli, M.3    Marchisio, P.C.4
  • 11
    • 0025787570 scopus 로고
    • Arg-Gly-Asp (RGD) peptides and the anti-vitronectin receptor antibody 23C6 inhibit dentine resorption and cell spreading by osteoclasts
    • M. A. Horton, M. L. Taylor, T. R. Arnett and M. H. Helfrich: Arg-Gly-Asp ( RGD) peptides and the antivitronectin receptor antibody 23C6 inhibit dentine resorption and cell spreading by osteoclasts. Exp Cell Res 195, 368-375 (1991) (Pubitemid 121006336)
    • (1991) Experimental Cell Research , vol.195 , Issue.2 , pp. 368-375
    • Horton, M.A.1    Taylor, M.L.2    Arnett, T.R.3    Helfrich, M.H.4
  • 15
    • 0034967249 scopus 로고    scopus 로고
    • Transforming growth factor-β induces osteoclast ruffling and chemotaxis: Potential role in osteoclast recruitment
    • M. F. Pilkington, S. M. Sims and S. J. Dixon: Transforming growth factor-β induces osteoclast ruffling and chemotaxis: potential role in osteoclast recruitment. J Bone Miner Res 16, 1237-1247 (2001) (Pubitemid 32574652)
    • (2001) Journal of Bone and Mineral Research , vol.16 , Issue.7 , pp. 1237-1247
    • Pilkington, M.F.1    Sims, S.M.2    Dixon, S.J.3
  • 16
    • 0027368962 scopus 로고
    • Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclasts
    • DOI 10.1084/jem.178.5.1733
    • K. Fuller, J. M. Owens, C. J. Jagger, A. Wilson, R. Moss and T. J. Chambers: Macrophage colony-stimulating factor stimulates survival and chemotactic behavior in isolated osteoclasts. J Exp Med 178, 1733-1744 (1993) (Pubitemid 23318452)
    • (1993) Journal of Experimental Medicine , vol.178 , Issue.5 , pp. 1733-1744
    • Fuller, K.1    Owens, J.M.2    Jagger, C.J.3    Wilson, A.4    Moss, R.5    Chambers, T.J.6
  • 18
    • 36849051963 scopus 로고    scopus 로고
    • The osteoclast: A multinucleated, hematopoietic-origin, bone-resorbing osteoimmune cell
    • DOI 10.1002/jcb.21553
    • Z. Bar-Shavit: The osteoclast: a multinucleated, hematopoietic-origin, bone-resorbing osteoimmune cell. J Cell Biochem 102, 1130-1139 (2007) (Pubitemid 350220034)
    • (2007) Journal of Cellular Biochemistry , vol.102 , Issue.5 , pp. 1130-1139
    • Bar-Shavit, Z.1
  • 20
    • 0034455103 scopus 로고    scopus 로고
    • Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis
    • DOI 10.1210/er.21.2.115
    • S. C. Manolagas: Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev 21, 115-137 (2000) (Pubitemid 32275592)
    • (2000) Endocrine Reviews , vol.21 , Issue.2 , pp. 115-137
    • Manolagas, S.C.1
  • 22
    • 0030611892 scopus 로고    scopus 로고
    • NF-κB inhibitors stimulate apoptosis of rabbit mature osteoclasts and inhibit bone resorption by these cells
    • DOI 10.1016/S0014-5793(97)00653-4, PII S0014579397006534
    • K. Ozaki, H. Takeda, H. Iwahashi, S. Kitano and S. Hanazawa: NF-κB inhibitors stimulate apoptosis of rabbit mature osteoclasts and inhibit bone resorption by these cells. FEBS Lett 410, 297-300 (1997) (Pubitemid 27304083)
    • (1997) FEBS Letters , vol.410 , Issue.2-3 , pp. 297-300
    • Ozaki, K.1    Takeda, H.2    Iwahashi, H.3    Kitano, S.4    Hanazawa, S.5
  • 23
    • 0141628920 scopus 로고    scopus 로고
    • Decoy oligodeoxynucleotides targeting NF-kappaB transcription factors: Induction of apoptosis in human primary osteoclasts
    • DOI 10.1016/S0006-2952(03)00470-2
    • L. Penolazzi, E. Lambertini, M. Borgatti, R. Piva, M. Cozzani, I. Giovannini, R. Naccari, G. Siciliani and R. Gambari: Decoy oligodeoxynucleotides targeting NF-kappaB transcription factors: induction of apoptosis in human primary osteoclasts. Biochem Pharmacol 66, 1189-1198 (2003) (Pubitemid 37130294)
    • (2003) Biochemical Pharmacology , vol.66 , Issue.7 , pp. 1189-1198
    • Penolazzi, L.1    Lambertini, E.2    Borgatti, M.3    Piva, R.4    Cozzani, M.5    Giovannini, I.6    Naccari, R.7    Siciliani, G.8    Gambari, R.9
  • 24
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • V. Ralevic and G. Burnstock: Receptors for purines and pyrimidines. Pharmacol Rev 50, 413-492 (1998) (Pubitemid 28477681)
    • (1998) Pharmacological Reviews , vol.50 , Issue.3 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 25
    • 20644446267 scopus 로고    scopus 로고
    • P2 nucleotide receptors in osteoclasts
    • DOI 10.1002/ddr.1180
    • L. N. Naemsch, X. B. Du, S. M. Sims and S. J. Dixon: P2 nucleotide receptors in osteoclasts. Drug Dev Res 53, 130-139 (2001) (Pubitemid 32845852)
    • (2001) Drug Development Research , vol.53 , Issue.2-3 , pp. 130-139
    • Dixon, S.J.1
  • 28
    • 0036788971 scopus 로고    scopus 로고
    • Molecular physiology of P2X receptors
    • R. A. North: Molecular physiology of P2X receptors. Physiol Rev 82, 1013-1067 (2002)
    • (2002) Physiol Rev , vol.82 , pp. 1013-1067
    • North, R.A.1
  • 30
    • 34250719722 scopus 로고    scopus 로고
    • Purine and pyrimidine receptors
    • DOI 10.1007/s00018-007-6497-0
    • G. Burnstock: Purine and pyrimidine receptors. Cell Mol Life Sci 64, 1471-1483 (2007) (Pubitemid 46954150)
    • (2007) Cellular and Molecular Life Sciences , vol.64 , Issue.12 , pp. 1471-1483
    • Burnstock, G.1
  • 31
    • 34248576759 scopus 로고    scopus 로고
    • Physiology and pathophysiology of purinergic neurotransmission
    • DOI 10.1152/physrev.00043.2006
    • G. Burnstock: Physiology and pathophysiology of purinergic neurotransmission. Physiol Rev 87, 659-797 (2007) (Pubitemid 47084682)
    • (2007) Physiological Reviews , vol.87 , Issue.2 , pp. 659-797
    • Burnstock, G.1
  • 32
    • 67949117176 scopus 로고    scopus 로고
    • Crystal structure of the ATP-gated P2X4 ion channel in the closed state
    • T. Kawate, J. C. Michel, W. T. Birdsong and E. Gouaux: Crystal structure of the ATP-gated P2X4 ion channel in the closed state. Nature 460, 592-598 (2009)
    • (2009) Nature , vol.460 , pp. 592-598
    • Kawate, T.1    Michel, J.C.2    Birdsong, W.T.3    Gouaux, E.4
  • 33
    • 0033491119 scopus 로고    scopus 로고
    • 4 purinoceptors mediate an ATP-activated, non-selective cation current in rabbit osteoclasts
    • L. N. Naemsch, A. F. Weidema, S. M. Sims, T. M. Underhill and S. J. Dixon: P2X4 purinoceptors mediate an ATP-activated, non-selective cation current in rabbit osteoclasts. J Cell Sci 112, 4425-4435 (1999) (Pubitemid 30122034)
    • (1999) Journal of Cell Science , vol.112 , Issue.23 , pp. 4425-4435
    • Naemsch, L.N.1    Weidema, A.F.2    Sims, S.M.3    Underhill, T.M.4    Dixon, S.J.5
  • 34
    • 0035914306 scopus 로고    scopus 로고
    • Activity-dependent development of P2X7 current and Ca2+ entry in rabbit osteoclasts
    • L. N. Naemsch, S. J. Dixon and S. M. Sims: Activity-dependent development of P2X7 current and Ca2+ entry in rabbit osteoclasts. J Biol Chem 276, 39107-39114 (2001)
    • (2001) J Biol Chem , vol.276 , pp. 39107-39114
    • Naemsch, L.N.1    Dixon, S.J.2    Sims, S.M.3
  • 36
    • 67649395964 scopus 로고    scopus 로고
    • Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells
    • M. Boumechache, M. Masin, J. M. Edwardson, D. C. Gorecki and R. Murrell-Lagnado: Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells. J Biol Chem 284, 13446-13454 (2009)
    • (2009) J Biol Chem , vol.284 , pp. 13446-13454
    • Boumechache, M.1    Masin, M.2    Edwardson, J.M.3    Gorecki, D.C.4    Murrell-Lagnado, R.5
  • 37
    • 0030757672 scopus 로고    scopus 로고
    • + channels in rat osteoclasts
    • DOI 10.1111/j.1469-7793.1997.303bh.x
    • A. F. Weidema, J. Barbera, S. J. Dixon and S. M. Sims: Extracellular nucleotides activate non-selective cation and Ca2+-dependent K+ channels in rat osteoclasts. J Physiol 503, 303-315 (1997) (Pubitemid 27423357)
    • (1997) Journal of Physiology , vol.503 , Issue.2 , pp. 303-315
    • Weidema, A.F.1    Barbera, J.2    Dixon, S.J.3    Sims, S.M.4
  • 38
    • 0029671045 scopus 로고    scopus 로고
    • An antagonist-insensitive P2X receptor expressed in epithelia and brain
    • G. Buell, C. Lewis, G. Collo, R. A. North and A. Surprenant: An antagonist-insensitive P2X receptor expressed in epithelia and brain. EMBO J 15, 55-62 (1996)
    • (1996) EMBO J , vol.15 , pp. 55-62
    • Buell, G.1    Lewis, C.2    Collo, G.3    North, R.A.4    Surprenant, A.5
  • 39
    • 67649666430 scopus 로고    scopus 로고
    • Functional interactions between P2X4 and P2X7 receptors from mouse salivary epithelia
    • G. Casas-Pruneda, J. P. Reyes, G. Perez-Flores, P. Perez-Cornejo and J. Arreola: Functional interactions between P2X4 and P2X7 receptors from mouse salivary epithelia. J Physiol 587, 2887-2901 (2009)
    • (2009) J Physiol , vol.587 , pp. 2887-2901
    • Casas-Pruneda, G.1    Reyes, J.P.2    Perez-Flores, G.3    Perez-Cornejo, P.4    Arreola, J.5
  • 42
    • 0032403025 scopus 로고    scopus 로고
    • 4 receptor
    • DOI 10.1016/S0028-3908(98)00153-1, PII S0028390898001531
    • I. J. Miller, A. D. Michel, I. P. Chessell and P. P. Humphrey: Cibacron blue allosterically modulates the rat P2X4 receptor. Neuropharmacology 37, 1579-1586 (1998) (Pubitemid 28550431)
    • (1998) Neuropharmacology , vol.37 , Issue.12 , pp. 1579-1586
    • Miller, K.J.1    Michel, A.D.2    Chessell, I.P.3    Humphrey, P.P.A.4
  • 43
    • 0034979213 scopus 로고    scopus 로고
    • Activation of P2Y but not P2X4 nucleotide receptors causes elevation of [Ca2+]i in mammalian osteoclasts
    • A. F. Weidema, S. J. Dixon and S. M. Sims: Activation of P2Y but not P2X4 nucleotide receptors causes elevation of [Ca2+]i in mammalian osteoclasts. Am J Physiol Cell Physiol 280, C1531-1539 (2001)
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Weidema, A.F.1    Dixon, S.J.2    Sims, S.M.3
  • 44
    • 33646424353 scopus 로고    scopus 로고
    • Pharmacological profiles of cloned mammalian P2Y-receptor subtypes
    • I. von Kugelgen: Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol Ther 110, 415-432 (2006)
    • (2006) Pharmacol Ther , vol.110 , pp. 415-432
    • Von Kugelgen, I.1
  • 46
    • 0036861712 scopus 로고    scopus 로고
    • Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor-κB ligand
    • DOI 10.1016/S8756-3282(02)00877-3, PII S8756328202008773
    • I. A. Buckley, R. A. Hipskind, A. Gartland, W. B. Bowler and J. A. Gallagher: Adenosine triphosphate stimulates human osteoclast activity via upregulation of osteoblast-expressed receptor activator of nuclear factor- κB ligand. Bone 31, 582-590 (2002) (Pubitemid 35449700)
    • (2002) Bone , vol.31 , Issue.5 , pp. 582-590
    • Buckley, K.A.1    Hipskind, R.A.2    Gartland, A.3    Bowler, W.B.4    Gallagher, J.A.5
  • 47
    • 0036510537 scopus 로고    scopus 로고
    • Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast P2X7 receptors
    • DOI 10.1074/jbc.M104608200
    • N. R. Jørgensen, Z. Henriksen, O. H. Sørensen, E. F. Eriksen, R. Civitelli and T. H. Steinberg: Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast P2X7 receptors. J Biol Chem 277, 7574-7580 (2002) (Pubitemid 34953156)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.9 , pp. 7574-7580
    • Jorgensen, N.R.1    Henriksen, Z.2    Sorensen, O.H.3    Eriksen, E.F.4    Civitelli, R.5    Steinberg, T.H.6
  • 48
    • 0042047374 scopus 로고    scopus 로고
    • 7 Receptor Inhibits Formation of Multinucleated Human Osteoclasts In Vitro
    • DOI 10.1007/s00223-002-2098-y
    • A. Gartland, K. A. Buckley, W. B. Bowler and J. A. Gallagher: Blockade of the pore-forming P2X7 receptor inhibits formation of multinucleated human osteoclasts in vitro. Calcif Tissue Int 73, 361-369 (2003) (Pubitemid 37409423)
    • (2003) Calcified Tissue International , vol.73 , Issue.4 , pp. 361-369
    • Gartland, A.1    Buckley, K.A.2    Bowler, W.B.3    Gallagher, J.A.4
  • 49
    • 30544443360 scopus 로고    scopus 로고
    • 7 receptor KN-62 antagonist are potent inducers of apoptosis of human primary osteoclasts
    • DOI 10.1007/s11373-005-9029-7
    • I. Penolazzi, E. Bianchini, E. Lambertini, P. G. Baraldi, R. Romagnoli, R. Piva and R. Gambari: NArylpiperazine modified analogues of the P2X7 receptor KN-62 antagonist are potent inducers of apoptosis of human primary osteoclasts. J Biomed Sci 12, 1013-1020 (2005) (Pubitemid 43081680)
    • (2005) Journal of Biomedical Science , vol.12 , Issue.6 , pp. 1013-1020
    • Penolazzi, L.1    Bianchini, E.2    Lambertini, E.3    Baraldi, P.G.4    Romagnoli, R.5    Piva, R.6    Gambari, R.7
  • 50
    • 67649460727 scopus 로고    scopus 로고
    • ATP-induced osteoclast function: The formation of sealing-zone like structure and the secretion of lytic granules via microtubuledeacetylation under the control of Syk
    • R. Hazama, X. Qu, K. Yokoyama, C. Tanaka, E. Kinoshita, J. He, S. Takahashi, K. Tohyama, H. Yamamura and Y. Tohyama: ATP-induced osteoclast function: the formation of sealing-zone like structure and the secretion of lytic granules via microtubuledeacetylation under the control of Syk. Genes Cells 14, 871-884 (2009)
    • (2009) Genes Cells , vol.14 , pp. 871-884
    • Hazama, R.1    Qu, X.2    Yokoyama, K.3    Tanaka, C.4    Kinoshita, E.5    He, J.6    Takahashi, S.7    Tohyama, K.8    Yamamura, H.9    Tohyama, Y.10
  • 51
    • 0029665112 scopus 로고    scopus 로고
    • The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
    • A. Surprenant, F. Rassendren, E. Kawashima, R. A. North and G. Buell: The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 272, 735-738 (1996)
    • (1996) Science , vol.272 , pp. 735-738
    • Surprenant, A.1    Rassendren, F.2    Kawashima, E.3    North, R.A.4    Buell, G.5
  • 53
    • 0030661885 scopus 로고    scopus 로고
    • 7 receptor
    • DOI 10.1016/S0028-3908(97)00141-X, PII S002839089700141X
    • A. Virginio, D. Church, R. A. North and A. Surprenant: Effects of divalent cations, protons and calmidazolium at the rat P2X7 receptor. Neuropharmacology 36, 1285-1294 (1997) (Pubitemid 27465616)
    • (1997) Neuropharmacology , vol.36 , Issue.9 , pp. 1285-1294
    • Virginio, C.1    Church, D.2    North, R.A.3    Surprenant, A.4
  • 57
    • 0035985277 scopus 로고    scopus 로고
    • 7 receptor in NG108-15 cells: Unique antagonist sensitivity and lack of pore formation
    • DOI 10.1254/jjp.88.428
    • T. Watano, I. Matsuoka and J. Kimura: Characteristics of ATP-induced current through P2X7 receptor in NG108-15 cells: unique antagonist sensitivity and lack of pore formation. Jpn J Pharmacol 88, 428-435 (2002) (Pubitemid 34516569)
    • (2002) Japanese Journal of Pharmacology , vol.88 , Issue.4 , pp. 428-435
    • Watano, T.1    Matsuoka, I.2    Kimura, J.3
  • 58
    • 0028087818 scopus 로고
    • 4-: Elimination of osteoclasts, macrophages, and their precursors from isolated bone cell populations and fetal bone rudiments
    • DOI 10.1007/BF00297190
    • W. E. Modderman, A. F. Weidema, T. Vrijheid-Lammers, A. M. Wassenaar and P. J. Nijweide: Permeabilization of cells of hemopoietic origin by extracellular ATP4-: elimination of osteoclasts, macrophages, and their precursors from isolated bone cell populations and fetal bone rudiments. Calcif Tissue Int 55, 141-150 (1994) (Pubitemid 24237537)
    • (1994) Calcified Tissue International , vol.55 , Issue.2 , pp. 141-150
    • Modderman, W.E.1    Weidema, A.F.2    Vrijheid-Lammers, T.3    Wassenaar, A.M.4    Nijweide, P.J.5
  • 60
    • 62149141016 scopus 로고    scopus 로고
    • Activation of P2X7 receptors causes isoform-specific translocation of protein kinase C in osteoclasts
    • S. Armstrong, A. Pereverzev, S. J. Dixon and S. M. Sims: Activation of P2X7 receptors causes isoform-specific translocation of protein kinase C in osteoclasts. J Cell Sci 122, 136-144 (2009)
    • (2009) J Cell Sci , vol.122 , pp. 136-144
    • Armstrong, S.1    Pereverzev, A.2    Dixon, S.J.3    Sims, S.M.4
  • 61
    • 33947707805 scopus 로고    scopus 로고
    • Activation of transcription factors by extracellular nucleotides in immune and related cell types
    • S. Armstrong, J. Korcok, S. M. Sims and S. J. Dixon: Activation of transcription factors by extracellular nucleotides in immune and related cell types. Purinergic Signal 3, 59-69 (2007)
    • (2007) Purinergic Signal , vol.3 , pp. 59-69
    • Armstrong, S.1    Korcok, J.2    Sims, S.M.3    Dixon, S.J.4
  • 62
    • 3242673859 scopus 로고    scopus 로고
    • Extracellular nucleotides act through P2X7 receptors to activate NF-κB in osteoclasts
    • DOI 10.1359/JBMR.040108
    • J. Korcok, L. N. Raimundo, H. Z. Ke, S. M. Sims and S. J. Dixon: Extracellular nucleotides act through P2X7 receptors to activate NF-κB in osteoclasts. J Bone Miner Res 19, 642-651 (2004) (Pubitemid 41071225)
    • (2004) Journal of Bone and Mineral Research , vol.19 , Issue.4 , pp. 642-651
    • Korcok, J.1    Raimundo, L.N.2    Ke, H.Z.3    Sims, S.M.4    Dixon, S.J.5
  • 64
    • 77957303845 scopus 로고    scopus 로고
    • The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro
    • A. Agrawal, K. A. Buckley, K. Bowers, M. Furber, J. A. Gallagher and A. Gartland: The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro. Purinergic Signal 6, 307-315 (2010)
    • (2010) Purinergic Signal , vol.6 , pp. 307-315
    • Agrawal, A.1    Buckley, K.A.2    Bowers, K.3    Furber, M.4    Gallagher, J.A.5    Gartland, A.6
  • 66
    • 77955497814 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of bone remodeling
    • I. J. Raggatt and N. C. Partridge: Cellular and molecular mechanisms of bone remodeling. J Biol Chem 285, 25103-25108 (2010)
    • (2010) J Biol Chem , vol.285 , pp. 25103-25108
    • Raggatt, I.J.1    Partridge, N.C.2
  • 67
    • 84860372743 scopus 로고    scopus 로고
    • Activation of P2X7 nucleotide receptors induces actin reorganization in osteoclasts
    • S. Armstrong, A. Pereverzev, E. Kwon, S. J. Dixon and S. M. Sims: Activation of P2X7 nucleotide receptors induces actin reorganization in osteoclasts. Eur Cells Mat 16, 42 (2008)
    • (2008) Eur Cells Mat , vol.16 , pp. 42
    • Armstrong, S.1    Pereverzev, A.2    Kwon, E.3    Dixon, S.J.4    Sims, S.M.5
  • 68
    • 0031921573 scopus 로고    scopus 로고
    • 7 purinoceptor by 17β-oestradiol
    • DOI 10.1111/j.1469-7793.1998.659bp.x
    • A. Cario-Toumaniantz, G. Loirand, L. Ferrier and P. Pacaud: Non-genomic inhibition of human P2X7 purinoceptor by 17β-oestradiol. J Physiol 508, 659-666 (1998) (Pubitemid 28220722)
    • (1998) Journal of Physiology , vol.508 , Issue.3 , pp. 659-666
    • Carlo-Toumaniantz, C.1    Loirand, G.2    Ferrier, L.3    Pacaud, P.4
  • 69
    • 10344230968 scopus 로고    scopus 로고
    • 7-R - Mediated apoptosis of uterine cervical cells by blocking calcium influx
    • DOI 10.1081/NCN-200027549
    • G. I. Gorodeski : Estrogen attenuates P2X7-R-mediated apoptosis of uterine cervical cells by blocking calcium influx. Nucleosides Nucleotides Nucleic Acids 23, 1287-1293 (2004) (Pubitemid 39625913)
    • (2004) Nucleosides, Nucleotides and Nucleic Acids , vol.23 , Issue.8-9 , pp. 1287-1293
    • Gorodeski, G.I.1
  • 72
    • 30044443068 scopus 로고    scopus 로고
    • 7 nucleotide receptor mediates skeletal mechanotransduction
    • DOI 10.1074/jbc.M506415200
    • J. Li, D. Liu, H. Z. Ke, R. L. Duncan and C. H. Turner: The P2X7 nucleotide receptor mediates skeletal mechanotransduction. J Biol Chem 280, 42952-42959 (2005) (Pubitemid 43049258)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.52 , pp. 42952-42959
    • Li, J.1    Liu, D.2    Ke, H.Z.3    Duncan, R.L.4    Turner, C.H.5
  • 73
    • 44649092795 scopus 로고    scopus 로고
    • P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: A signaling axis promoting osteogenesis
    • DOI 10.1083/jcb.200708037
    • N. Panupinthu, J. T. Rogers, L. Zhao, L. P. Solano-Flores, F. Possmayer, S. M. Sims and S. J. Dixon: P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis. J Cell Biol 181, 859-871 (2008) (Pubitemid 351786989)
    • (2008) Journal of Cell Biology , vol.181 , Issue.5 , pp. 859-871
    • Panupinthu, N.1    Rogers, J.T.2    Zhao, L.3    Solano-Flores, L.P.4    Possmayer, F.5    Sims, S.M.6    Dixon, S.J.7
  • 79
    • 20444458308 scopus 로고    scopus 로고
    • P2Y6 nucleotide receptors activate NF-κB and increase survival of osteoclasts
    • DOI 10.1074/jbc.M410764200
    • J. Korcok, L. N. Raimundo, X. Du, S. M. Sims and S. J. Dixon: P2Y6 nucleotide receptors activate NF-κB and increase survival of osteoclasts. J Biol Chem 280, 16909-16915 (2005) (Pubitemid 41389150)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.17 , pp. 16909-16915
    • Korcok, J.1    Raimundo, L.N.2    Du, X.3    Sims, S.M.4    Dixon, S.J.5
  • 80
    • 0027249813 scopus 로고
    • ATP induces an intracellular calcium pulse in osteoclasts
    • DOI 10.1006/bbrc.1993.1225
    • H. Yu and J. Ferrier: ATP induces an intracellular calcium pulse in osteoclasts. Biochem Biophys Res Commun 191, 357-363 (1993) (Pubitemid 23222643)
    • (1993) Biochemical and Biophysical Research Communications , vol.191 , Issue.2 , pp. 357-363
    • Yu, H.1    Ferrier, J.2
  • 81
    • 0028670188 scopus 로고
    • Mechanisms of ATP-induced Ca2+ signaling in osteoclasts
    • H. Yu and J. Ferrier: Mechanisms of ATP-induced Ca2+ signaling in osteoclasts. Cell Signal 6, 905-914 (1994)
    • (1994) Cell Signal , vol.6 , pp. 905-914
    • Yu, H.1    Ferrier, J.2
  • 83
    • 0034039640 scopus 로고    scopus 로고
    • Electrophysiological characterization of ion channels in osteoclasts isolated from human deciduous teeth
    • DOI 10.1016/S8756-3282(00)00287-8, PII S8756328200002878
    • A. F. Weidema, S. J. Dixon and S. M. Sims: Electrophysiological characterization of ion channels in osteoclasts isolated from human deciduous teeth. Bone 27, 5-11 (2000) (Pubitemid 30365071)
    • (2000) Bone , vol.27 , Issue.1 , pp. 5-11
    • Weidema, A.F.1    Dixon, S.J.2    Sims, S.M.3
  • 84
    • 0035025090 scopus 로고    scopus 로고
    • 1 receptor on bone cells
    • DOI 10.1096/fj.00-0395com
    • A. Hoebertz, S. Meghji, G. Burnstock and T. R. Arnett: Extracellular ADP is a powerful osteolytic agent: evidence for signaling through the P2Y1 receptor on bone cells. FASEB J 15, 1139-1148 (2001) (Pubitemid 32436299)
    • (2001) FASEB Journal , vol.15 , Issue.7 , pp. 1139-1148
    • Hoebertz, A.1    Meghji, S.2    Burnstock, G.3    Arnett, T.R.4
  • 85
    • 0029052149 scopus 로고
    • Identification and cloning of human P2U purinoceptor present in osteoclastoma, bone, and osteoblasts
    • W. B. Bowler, M. A. Birch, J. A. Gallagher and G. Bilbe: Identification and cloning of human P2U purinoceptor present in osteoclastoma, bone, and osteoblasts. J Bone Miner Res 10, 1137-1145 (1995)
    • (1995) J Bone Miner Res , vol.10 , pp. 1137-1145
    • Bowler, W.B.1    Birch, M.A.2    Gallagher, J.A.3    Bilbe, G.4
  • 86
    • 0032031288 scopus 로고    scopus 로고
    • P2Y2 receptors are expressed by human osteoclasts of giant cell tumor but do not mediate ATP-induced bone resorption
    • DOI 10.1016/S8756-3282(97)00280-9, PII S8756328297002809
    • W. B. Bowler, A. Littlewood-Evans, G. Bilbe, J. A. Gallagher and C. J. Dixon: P2Y2 receptors are expressed by human osteoclasts of giant cell tumor but do not mediate ATP-induced bone resorption. Bone 22, 195-200 (1998) (Pubitemid 28127474)
    • (1998) Bone , vol.22 , Issue.3 , pp. 195-200
    • Bowler, W.B.1    Littlewood-Evans, A.2    Bilbe, G.3    Gallagher, J.A.4    Dixon, C.J.5
  • 87
    • 0033402740 scopus 로고    scopus 로고
    • Calcium signalling via multiple P2 purinoceptor subtypes in rat osteoclasts
    • S. H. Wiebe, S. M. Sims and S. J. Dixon: Calcium signalling via multiple P2 purinoceptor subtypes in rat osteoclasts. Cell Physiol Biochem 9, 323-337 (1999) (Pubitemid 30021940)
    • (1999) Cellular Physiology and Biochemistry , vol.9 , Issue.6 , pp. 323-337
    • Wiebe, S.H.1    Sims, S.M.2    Jeffrey Dixon, S.3
  • 89
    • 0003982630 scopus 로고    scopus 로고
    • ATP is a potent stimulator of the activation and formation of rodent osteoclasts
    • DOI 10.1111/j.1469-7793.1998.495bh.x
    • M. S. Morrison, L. Turin, B. F. King, G. Burnstock and T. R. Arnett: ATP is a potent stimulator of the activation and formation of rodent osteoclasts. J Physiol 511, 495-500 (1998) (Pubitemid 28444617)
    • (1998) Journal of Physiology , vol.511 , Issue.2 , pp. 495-500
    • Morrison, M.S.1    Turin, L.2    King, B.F.3    Burnstock, G.4    Arnett, T.R.5
  • 90
    • 0034081759 scopus 로고    scopus 로고
    • P2 purinergic receptors on osteoblasts and osteoclasts: Potential targets for drug development
    • DOI 10.1002/(SICI)1098-2299(200003) 49:3<187::AID-DDR9>3.0.CO;2-F
    • S. J. Dixon and S. M. Sims: P2 purinergic receptors on osteoblasts and osteoclasts: Potential targets for drug development. Drug Dev Res 49, 187-200 (2000) (Pubitemid 30324635)
    • (2000) Drug Development Research , vol.49 , Issue.3 , pp. 187-200
    • Dixon, S.J.1    Sims, S.M.2
  • 91
    • 0033680583 scopus 로고    scopus 로고
    • P2 purinergic receptors: Modulation of cell function and therapeutic potential
    • G. Burnstock and M. Williams: P2 purinergic receptors: modulation of cell function and therapeutic potential. J Pharmacol Exp Ther 295, 862-869 (2000)
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 862-869
    • Burnstock, G.1    Williams, M.2
  • 92
    • 65649105317 scopus 로고    scopus 로고
    • P2 nucleotide receptor signaling in osteoclasts
    • Eds: G. Burnstock and T. R. Arnett. CRC Press, Boca Raton
    • J. Korcok, S. M. Sims and S. J. Dixon: P2 nucleotide receptor signaling in osteoclasts. In: Nucleotides and regulation of bone cell function. Eds: G. Burnstock and T. R. Arnett. CRC Press, Boca Raton (2007)
    • (2007) Nucleotides and Regulation of Bone Cell Function
    • Korcok, J.1    Sims, S.M.2    Dixon, S.J.3


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