RAGE during infectious diseases

Frontiers in Bioscience - Scholar

Volumn 3 S, Issue 3, 2011, Pages 1119-1132

  Van Zoelen, Marieke A D ^a,b,c   Achouiti, Ahmed ^a,b   Van Der Poll, Tom ^a,b  

^a Center for Infection and Immunity Amsterdam CINIMA   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

DAMPs; HMGB1; Host defense; Infection; PAMPs; Pneumonia; RAGE; Review; S100A12; Sepsis

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; AMYLOID; CD18 ANTIGEN; COLLAGEN TYPE 2; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN S 100; PROTEIN S100 A12; PROTEIN S100B; PROTEIN S100P; UNCLASSIFIED DRUG; ADVANCED GLYCOSYLATION END PRODUCT RECEPTOR; ADVANCED GLYCOSYLATION END-PRODUCT RECEPTOR; IMMUNOGLOBULIN RECEPTOR; LIGAND; S100A12 PROTEIN, HUMAN;

ARTHRITIS; ARTICLE; ATHEROSCLEROSIS; BACTERIAL GROWTH; BETA SHEET; COMMUNITY ACQUIRED PNEUMONIA; DELAYED HYPERSENSITIVITY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; ESCHERICHIA COLI; EXPERIMENTAL MODEL; HOSPITAL ACQUIRED PNEUMONIA; HOST RESISTANCE; HUMAN; IMMUNE RESPONSE; INFECTION; INFLAMMATION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; KLEBSIELLA PNEUMONIAE INFECTION; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; LIGAND BINDING; LIGATION; LIVER INJURY; LUNG TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PUNCTURE; SEASONAL INFLUENZA; SEPSIS; STREPTOCOCCUS PNEUMONIA; BIOLOGICAL MODEL; COMMUNICABLE DISEASE; GENE EXPRESSION REGULATION; IMMUNOLOGY; LEUKOCYTE; LUNG; METABOLISM; PHYSIOLOGY; PNEUMONIA; REVIEW; SIGNAL TRANSDUCTION;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS PNEUMONIAE;

ANTIGENS, CD18; COMMUNICABLE DISEASES; GENE EXPRESSION REGULATION; HUMANS; LEUKOCYTES; LIGANDS; LUNG; MODELS, BIOLOGICAL; NF-KAPPA B; PNEUMONIA; RECEPTORS, IMMUNOLOGIC; S100 PROTEINS; SIGNAL TRANSDUCTION;

EID: 80053109725     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: None     Document Type: Article

References (119)

1. CA Janeway Jr., R Medzhitov: Innate Immune Recognition. Annu Rev Immunol 20, 197-216 (2002) (Pubitemid 34293424)
2. ME Bianchi: DAMPs, PAMPs and Alarmins: All We Need to Know About Danger. J Leukoc Biol 81, 1-5 (2007) (Pubitemid 46028489)
3. HE Harris, A Raucci: Alarmin(g) News About Danger: Workshop on Innate Danger Signals and HMGB1. EMBO Rep 7, 774-778 (2006) (Pubitemid 44275393)
4. P Scaffidi, T Misteli, ME Bianchi: Release of Chromatin Protein HMGB1 by Necrotic Cells Triggers Inflammation. Nature 418, 191-195 (2002) (Pubitemid 34773774)
5. Y Liu, GY Chen, P Zheng: CD24-Siglec G/10 Discriminates Danger-From Pathogen-Associated Molecular Patterns. Trends Immunol 30, 557-561 (2009)
6. G Sorci, F Riuzzi, C Arcuri, I Giambanco, R Donato: Amphoterin Stimulates Myogenesis and Counteracts the Antimyogenic Factors Basic Fibroblast Growth Factor and S100B Via RAGE Binding. Mol Cell Biol 24, 4880-4894 (2004) (Pubitemid 38668053)
7. R Liu, S Mori, H Wake, J Zhang, K Liu, Y Izushi, HK Takahashi, B Peng, M Nishibori: Establishment of in vitro Binding Assay of High Mobility Group Box-1 and S100A12 to Receptor for Advanced Glycation Endproducts: Heparin's Effect on Binding. Acta Med Okayama 63, 203-211 (2009)
8. G Srikrishna, J Nayak, B Weigle, A Temme, D Foell, L Hazelwood, A Olsson, N Volkmann, D Hanein, HH Freeze: Carboxylated N-Glycans on RAGE Promote S100A12 Binding and Signaling. J Cell Biochem 110, 645-659 (2010)
9. J Xie, DS Burz, W He, IB Bronstein, I Lednev, A Shekhtman: Hexameric Calgranulin C (S100A12) Binds to the Receptor for Advanced Glycated End Products (RAGE) Using Symmetric Hydrophobic Target-Binding Patches. J Biol Chem 282, 4218-4231 (2007) (Pubitemid 47084493)
10. JV Valencia, M Mone, J Zhang, M Weetall, FP Buxton, TE Hughes: Divergent Pathways of Gene Expression Are Activated by the RAGE Ligands S100b and AGE-BSA. Diabetes 53, 743-751 (2004) (Pubitemid 38270645)
11. T Arumugam, DM Simeone, AM Schmidt, CD Logsdon: S100P Stimulates Cell Proliferation and Survival Via Receptor for Activated Glycation End Products (RAGE). J Biol Chem 279, 5059-5065 (2004) (Pubitemid 38220521)
12. SD Yan, H Zhu, A Zhu, A Golabek, H Du, A Roher, J Yu, C Soto, AM Schmidt, D Stern, M Kindy: Receptor-Dependent Cell Stress and Amyloid Accumulation in Systemic Amyloidosis. Nat Med 6, 643-651 (2000) (Pubitemid 30398787)
13. SD Yan, X Chen, J Fu, M Chen, H Zhu, A Roher, T Slattery, L Zhao, M Nagashima, J Morser, A Migheli, P Nawroth, D Stern, AM Schmidt: RAGE and Amyloid-Beta Peptide Neurotoxicity in Alzheimer's Disease. Nature 382, 685-691 (1996) (Pubitemid 26282167)
14. T Chavakis, A Bierhaus, N Al Fakhri, D Schneider, S Witte, T Linn, M Nagashima, J Morser, B Arnold, KT Preissner, PP Nawroth: The Pattern Recognition Receptor (RAGE) Is a Counterreceptor for Leukocyte Integrins: a Novel Pathway for Inflammatory Cell Recruitment. J Exp Med 198, 1507-1515 (2003) (Pubitemid 37467165)
15. IE Dumitriu, P Baruah, AA Manfredi, ME Bianchi, P Rovere-Querini: HMGB1: Guiding Immunity From Within. Trends Immunol 26, 381-387 (2005) (Pubitemid 40835844)
16. A Bierhaus, S Schiekofer, M Schwaninger, M Andrassy, PM Humpert, J Chen, M Hong, T Luther, T Henle, I Kloting, M Morcos, M Hofmann, H Tritschler, B Weigle, M Kasper, M Smith, G Perry, AM Schmidt, DM Stern, HU Haring, E Schleicher, PP Nawroth: Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-KappaB. Diabetes 50, 2792-2808 (2001) (Pubitemid 33733131)
17. B Liliensiek, MA Weigand, A Bierhaus, W Nicklas, M Kasper, S Hofer, J Plachky, HJ Grone, FC Kurschus, AM Schmidt, SD Yan, E Martin, E Schleicher, DM Stern, GG Hammerling, PP Nawroth, B Arnold: Receptor for Advanced Glycation End Products (RAGE) Regulates Sepsis but Not the Adaptive Immune Response. J Clin Invest 113, 1641-1650 (2004) (Pubitemid 39071688)
18. G Cataldegirmen, S Zeng, N Feirt, N Ippagunta, H Dun, W Qu, Y Lu, LL Rong, MA Hofmann, T Kislinger, SI Pachydaki, DG Jenkins, A Weinberg, J Lefkowitch, X Rogiers, SF Yan, AM Schmidt, JC Emond: RAGE Limits Regeneration After Massive Liver Injury by Coordinated Suppression of TNF-Alpha and NFKappaB. J Exp Med 201, 473-484 (2005) (Pubitemid 40229421)
19. S Zeng, N Feirt, MGoldstein, J Guarrera, N Ippagunta, U Ekong, H Dun, Y Lu, W Qu, AM Schmidt, JC Emond: Blockade of Receptor for Advanced Glycation End Product (RAGE) Attenuates Ischemia and Reperfusion Injury to the Liver in Mice. Hepatology 39, 422-432 (2004) (Pubitemid 38222183)
20. U Ekong, S Zeng, H Dun, N Feirt, J Guo, N Ippagunta, JV Guarrera, Y Lu, A Weinberg, W Qu, R Ramasamy, AM Schmidt, JC Emond: Blockade of the Receptor for Advanced Glycation End Products Attenuates Acetaminophen-Induced Hepatotoxicity in Mice. J Gastroenterol Hepatol 21, 682-688 (2006)
21. L Park, KG Raman, KJ Lee, Y Lu, LJ Ferran Jr., WS Chow, D Stern, AM Schmidt: Suppression of Accelerated Diabetic Atherosclerosis by the Soluble Receptor for Advanced Glycation Endproducts. Nat Med 4, 1025-1031 (1998) (Pubitemid 28417334)
22. MT Goova, J Li, T Kislinger, W Qu, Y Lu, LG Bucciarelli, S Nowygrod, BM Wolf, X Caliste, SF Yan, DM Stern, AM Schmidt: Blockade of Receptor for Advanced Glycation End-Products Restores Effective Wound Healing in Diabetic Mice. Am J Pathol 159, 513-525 (2001) (Pubitemid 32751082)
23. MA Hofmann, S Drury, BI Hudson, MR Gleason, W Qu, Y Lu, E Lalla, S Chitnis, J Monteiro, MH Stickland, LG ucciarelli, B Moser, G Moxley, S Itescu, PH Grant, PK Gregersen, DM Stern, AM Schmidt: RAGE and Arthritis: the G82S Polymorphism Amplifies the Inflammatory Response. Genes Immun 3, 123-135 (2002) (Pubitemid 38961122)
24. A Bierhaus, DM Stern, PP Nawroth: RAGE in Inflammation: a New Therapeutic Target? Curr Opin Investig Drugs 7, 985-991 (2006) (Pubitemid 44756124)
25. Y Chen, SS Yan, J Colgan, HP Zhang, J Luban, AM Schmidt, D Stern, KC Herold: Blockade of Late Stages of Autoimmune Diabetes by Inhibition of the Receptor for Advanced Glycation End Products. J Immunol 173, 1399-1405 (2004) (Pubitemid 38924321)
26. B Moser, DD Desai, MP Downie, Y Chen, SF Yan, K Herold, AM Schmidt, R Clynes: Receptor for Advanced Glycation End Products Expression on T Cells Contributes to Antigen-Specific Cellular Expansion in vivo. J Immunol 179, 8051-8058 (2007)
27. O Hori, J Brett, T Slattery, R Cao, J Zhang, JX Chen, M Nagashima, ER Lundh, S Vijay, D Nitecki: The Receptor for Advanced Glycation End Products (RAGE) Is a Cellular Binding Site for Amphoterin. Mediation of Neurite Outgrowth and Co-Expression of Rage and Amphoterin in the Developing Nervous System. J Biol Chem 270, 25752-25761 (1995)
28. A Bierhaus, KM Haslbeck, PM Humpert, B Liliensiek, T Dehmer, M Morcos, AA Sayed, M Andrassy, S Schiekofer, JG Schneider, JB Schulz, D Heuss, B Neundorfer, S Dierl, J Huber, H Tritschler, AM Schmidt, M Schwaninger, HU Haering, E Schleicher, M Kasper, DM Stern, B Arnold, PP Nawroth: Loss of Pain Perception in Diabetes Is Dependent on a Receptor of the Immunoglobulin Superfamily. J Clin Invest 114, 1741-1751 (2004) (Pubitemid 40385530)
29. C Cheng, K Tsuneyama, R Kominami, H Shinohara, S Sakurai, H Yonekura, T Watanabe, Y Takano, H Yamamoto, Y Yamamoto: Expression Profiling of Endogenous Secretory Receptor for Advanced Glycation End Products in Human Organs. Mod Pathol 18, 1385-1396 (2005) (Pubitemid 41348659)
30. JM Englert, LE Hanford, N Kaminski, JM Tobolewski, RJ Tan, CL Fattman, L Ramsgaard, TJ Richards, I Loutaev, PP Nawroth, M Kasper, A Bierhaus, TD Oury: A Role for the Receptor for Advanced Glycation End Products in Idiopathic Pulmonary Fibrosis. Am J Pathol 172, 583-591 (2008) (Pubitemid 351354532)
31. P Morbini, C Villa, I Campo, M Zorzetto, S Inghilleri, M Luisetti: The Receptor for Advanced Glycation End Products and Its Ligands: a New Inflammatory Pathway in Lung Disease? Mod Pathol 19, 1437-1445 (2006) (Pubitemid 44624162)
32. T Uchida, M Shirasawa, LB Ware, K Kojima, Y Hata, K Makita, G Mednick, ZA Matthay, MA Matthay: Receptor for Advanced Glycation End-Products Is a Marker of Type I Cell Injury in Acute Lung Injury. Am J Respir Crit Care Med 173, 1008-1015 (2006)
33. H Wittkowski, A Sturrock, MA van Zoelen, D Viemann, T van der Poll, JR Hoidal, J Roth, D Foell: Neutrophil-Derived S100A12 in Acute Lung Injury and Respiratory Distress Syndrome. Crit Care Med 35, 1369-1375 (2007) (Pubitemid 46642668)
34. ST Buckley, C Ehrhardt: The Receptor for Advanced Glycation End Products (RAGE) and the Lung. J Biomed Biotechnol 917108 (2010)
35. MA Queisser, FM Kouri, M Konigshoff, M Wygrecka, U Schubert, O Eickelberg, KT Preissner: Loss of RAGE in Pulmonary Fibrosis: Molecular Relations to Functional Changes in Pulmonary Cell Types. Am J Respir Cell Mol Biol 39, 337-345 (2008)
36. N Demling, C Ehrhardt, M Kasper, M Laue, L Knels, EP Rieber: Promotion of Cell Adherence and Spreading: a Novel Function of RAGE, the Highly Selective Differentiation Marker of Human Alveolar Epithelial Type I Cells. Cell Tissue Res 323, 475-488 (2006) (Pubitemid 43228103)
37. H Fehrenbach, M Kasper, T Tschernig, MS Shearman, D Schuh, M Muller: Receptor for Advanced Glycation Endproducts (RAGE) Exhibits Highly Differential Cellular and Subcellular Localisation in Rat and Human Lung. Cell Mol Biol (Noisy -le-grand) 44, 1147-1157 (1998)
38. M Shirasawa, N Fujiwara, S Hirabayashi, H Ohno, J Iida, K Makita, Y Hata. Receptor for Advanced Glycation End-Products Is a Marker of Type I Lung Alveolar Cells. Genes Cells 9, 165-174 (2004) (Pubitemid 38312960)
39. F Katsuoka, Y Kawakami, T Arai, H Imuta, M Fujiwara, H Kanma, K Yamashita: Type II Alveolar Epithelial Cells in Lung Express Receptor for Advanced Glycation End Products (RAGE) Gene. Biochem Biophys Res Commun 238, 512-516 (1997) (Pubitemid 27464418)
40. K Dahlin, EM Mager, L Allen, Z Tigue, L Goodglick, M Wadehra, L Dobbs: Identification of Genes Differentially Expressed in Rat Alveolar Type I Cells. Am J Respir Cell Mol Biol 31, 309-316 (2004) (Pubitemid 39180300)
41. M He, H Kubo, K Ishizawa, AE Hegab, Y Yamamoto, H Yamamoto, M Yamaya: The Role of the Receptor for Advanced Glycation End-Products in Lung Fibrosis. Am J Physiol Lung Cell Mol Physiol 293, L1427-L1436 (2007) (Pubitemid 350255025)
42. PR Reynolds, RE Schmitt, SD Kasteler, A Sturrock, K Sanders, A Bierhaus, PP Nawroth, R Paine, JR Hoidal: Receptors for Advanced Glycation End-Products Targeting Protect Against Hyperoxia-Induced Lung Injury in Mice. Am J Respir Cell Mol Biol 42, 545-551 (2010)
43. AM Schmidt, SD Yan, SF Yan, DM Stern: The Multiligand Receptor RAGE As a Progression Factor Amplifying Immune and Inflammatory Responses. J Clin Invest 108, 949-955 (2001) (Pubitemid 32946067)
44. A Raucci, S Cugusi, A Antonelli, SM Barabino, L Monti, A Bierhaus, K Reiss, P Saftig, ME Bianchi: A Soluble Form of the Receptor for Advanced Glycation Endproducts (RAGE) Is Produced by Proteolytic Cleavage of the Membrane-Bound Form by the Sheddase a Disintegrin and Metalloprotease 10 (ADAM10). FASEB J 22, 3716-3727 (2008)
45. A Bierhaus, PM Humpert, M Morcos, T Wendt, T Chavakis, B Arnold, DM Stern, PP Nawroth: Understanding RAGE, the Receptor for Advanced Glycation End Products. J Mol Med 83, 876-886 (2005) (Pubitemid 41598688)
46. JO Thomas: HMG1 and 2: Architectural DNA-Binding Proteins. Biochem Soc Trans 29, 395-401 (2001)
47. MT Lotze, KJ Tracey: High-Mobility Group Box 1 Protein (HMGB1): Nuclear Weapon in the Immune Arsenal. Nat Rev Immunol 5, 331-342 (2005) (Pubitemid 40516158)
48. AP Wheeler, GR Bernard: Treating Patients With Severe Sepsis. N Engl J Med 340, 207-214 (1999) (Pubitemid 29063218)
49. DC Angus, WT Linde-Zwirble, J Lidicker, G Clermont, J Carcillo, MR Pinsky: Epidemiology of Severe Sepsis in the United States: Analysis of Incidence, Outcome, and Associated Costs of Care. Crit Care Med 29, 1303-1310 (2001) (Pubitemid 32641789)
50. H Wang, O Bloom, M Zhang, JM Vishnubhakat, M Ombrellino, J Che, A Frazier, H Yang, S Ivanova, L Borovikova, KR Manogue, E Faist, E Abraham, J Andersson, U Andersson, PE Molina, NN Abumrad, A Sama, KJ Tracey:. HMG-1 As a Late Mediator of Endotoxin Lethality in Mice. Science 285, 248-51 (1999) (Pubitemid 29329996)
51. J Sunden-Cullberg, A Norrby-Teglund, A Rouhiainen, H Rauvala, G Herman, KJ Tracey, ML Lee, J Andersson, L Tokics, CJ Treutiger: Persistent Elevation of High Mobility Group Box-1 Protein (HMGB1) in Patients With Severe Sepsis and Septic Shock. Crit Care Med 33, 564-573 (2005) (Pubitemid 40365558)
52. H Ueno, T Matsuda, S Hashimoto, F Amaya, Y Kitamura, M Tanaka, A Kobayashi, I Maruyama, S Yamada, N Hasegawa, J Soejima, H Koh, A Ishizaka: Contributions of High Mobility Group Box Protein in Experimental and Clinical Acute Lung Injury. Am J Respir Crit Care Med 170, 1310-1316 (2004) (Pubitemid 39657195)
53. MA van Zoelen, PF Laterre, SQ van Veen, JW van Till, X Wittebole, P Bresser, MW Tanck, T Dugernier, A Ishizaka, MA Boermeester, T van der Poll: Systemic and Local High Mobility Group Box 1 Concentrations During Severe Infection. Crit Care Med 35, 2799-2804 (2007) (Pubitemid 350175778)
54. H Yang, M Ochani, J Li, X Qiang, M Tanovic, HE Harris, SM Susarla, L Ulloa, H Wang, R DiRaimo, CJ Czura, H Wang, J Roth, HS Warren, MP Fink, MJ Fenton, U Andersson, KJ: Reversing Established Sepsis With Antagonists of Endogenous High-Mobility Group Box 1. Proc Natl Acad Sci U S A 101, 296-301 (2004) (Pubitemid 38084244)
55. S Qin, H Wang, R Yuan, H Li, M Ochani, K Ochani, M Rosas-Ballina, CJ Czura, JM Huston, E Miller, X Lin, B Sherry, A Kumar, G Larosa, W Newman, KJ Tracey, H Yang: Role of HMGB1 in Apoptosis-Mediated Sepsis Lethality. J Exp Med 203, 1637-1642 (2006) (Pubitemid 44036267)
56. K Suda, Y Kitagawa, S Ozawa, Y Saikawa, M Ueda, M Ebina, S Yamada, S Hashimoto, S Fukata, E Abraham, I Maruyama, M Kitajima, A Ishizaka: Anti-High-Mobility Group Box Chromosomal Protein 1 Antibodies Improve Survival of Rats With Sepsis. World J Surg 30, 1755-1762 (2006) (Pubitemid 44411235)
57. L Ulloa, M Ochani, H Yang, M Tanovic, D Halperin, R Yang, CJ Czura, MP Fink, KJ Tracey: Ethyl Pyruvate Prevents Lethality in Mice With Established Lethal Sepsis and Systemic Inflammation. Proc Natl Acad Sci U S A 99, 12351-12356 (2002)
58. H Wang, H Liao, M Ochani, M Justiniani, X Lin, L Yang, Y Al Abed, H Wang, C Metz, EJ Miller, KJ Tracey, L Ulloa: Cholinergic Agonists Inhibit HMGB1 Release and Improve Survival in Experimental Sepsis. Nat Med 10, 1216-1221 (2004) (Pubitemid 39540438)
59. RS Hotchkiss, DW Nicholson: Apoptosis and Caspases Regulate Death and Inflammation in Sepsis. Nat Rev Immunol 6, 813-822 (2006) (Pubitemid 44631650)
60. RS Hotchkiss, KC Chang, PE Swanson, KW Tinsley, JJ Hui, P Klender, S Xanthoudakis, S Roy, C Black, E Grimm, R Aspiotis, Y Han, DW Nicholson, IE Karl: Caspase Inhibitors Improve Survival in Sepsis: a Critical Role of the Lymphocyte. Nat Immunol 1, 496-501 (2000)
61. J Tian, AM Avalos, SY Mao, B Chen, K Senthil, H Wu, P Parroche, S Drabic, D Golenbock, C Sirois, J Hua, LL An, L Audoly, G La Rosa, A Bierhaus, P Naworth, A Marshak-Rothstein, ML Crow, KA Fitzgerald, E Latz, PA Kiener, AJ Coyle: Toll-Like Receptor 9-Dependent Activation by DNA-Containing Immune Complexes Is Mediated by HMGB1 and RAGE. Nat Immunol 8, 487-496 (2007) (Pubitemid 46605917)
62. H Yang, HS Hreggvidsdottir, K Palmblad, H Wang, M Ochani, J Li, B Lu, S Chavan, M Rosas-Ballina, Y Al-Abed, S Akira, A Bierhaus, H Erlandsson-Harris, U Andersson, KJ Tracey: A Critical Cysteine Is Required for HMGB1 Binding to Toll-Like Receptor 4 and Activation of Macrophage Cytokine Release. Proc Natl Acad Sci U S A (2010)
63. T Vogl, C Propper, M Hartmann, A Strey, K Strupat, C van den B, C Sorg, J Roth: S100A12 Is Expressed Exclusively by Granulocytes and Acts Independently From MRP8 and MRP14. J Biol Chem 274, 25291-25296 (1999)
64. F Guignard, J Mauel, M Markert: Identification and Characterization of a Novel Human Neutrophil Protein Related to the S100 Family. Biochem J 309 ( Pt 2); 395-401 (1995)
65. EC Dell'Angelica, CH Schleicher, JA Santome: Primary Structure and Binding Properties of Calgranulin C, a Novel S100-Like Calcium-Binding Protein From Pig Granulocytes. J Biol Chem 269, 28929-28936 (1994)
66. D Foell, T Kucharzik, M Kraft, T Vogl, C Sorg, W Domschke, J Roth: Neutrophil Derived Human S100A12 (EN-RAGE) Is Strongly Expressed During Chronic Active Inflammatory Bowel Disease. Gut 52, 847-853 (2003) (Pubitemid 36613492)
67. MA Sidler, ST Leach, AS Day: Fecal S100A12 and Fecal Calprotectin As Noninvasive Markers for Inflammatory Bowel Disease in Children. Inflamm Bowel Dis 14, 359-366 (2008) (Pubitemid 351441325)
68. D Foell, S Seeliger, T Vogl, HG Koch, H Maschek, E Harms, C Sorg, J Roth: Expression of S100A12 (ENRAGE) in Cystic Fibrosis. Thorax 58, 613-617 (2003) (Pubitemid 36808133)
69. Y Mori, A Kosaki, N Kishimoto, T Kimura, K Iida, M Fukui, F Nakajima, M Nagahara, M Urakami, T Iwasaka, H Matsubara: Increased Plasma S100A12 (EN-RAGE) Levels in Hemodialysis Patients With Atherosclerosis. Am J Nephrol 29, 18-24 (2009)
70. D Foell, D Kane, B Bresnihan, T Vogl, W Nacken, C Sorg, O FitzGerald, J Roth: Expression of the Pro-Inflammatory Protein S100A12 (EN-RAGE) in Rheumatoid and Psoriatic Arthritis. Rheumatology (Oxford) 42, 1383-1389 (2003) (Pubitemid 37407031)
71. D Foell, F Ichida, T Vogl, X Yu, R Chen, T Miyawaki, C Sorg, J Roth: S100A12 (EN-RAGE) in Monitoring Kawasaki Disease. Lancet 361, 1270-1272 (2003) (Pubitemid 36428584)
72. F Ye, D Foell, KI Hirono, T Vogl, C Rui, X Yu, S Watanabe, K Watanabe, K Uese, I Hashimoto, J Roth, F Ichida, T Miyawaki: Neutrophil-Derived S100A12 Is Profoundly Upregulated in the Early Stage of Acute Kawasaki Disease. Am J Cardiol 94, 840-844 (2004) (Pubitemid 39221519)
73. K Zen, CX Chen, YT Chen, R Wilton, Y Liu: Receptor for Advanced Glycation Endproducts Mediates Neutrophil Migration Across Intestinal Epithelium. J Immunol 178, 2483-2490 (2007) (Pubitemid 46233449)
74. VV Orlova, EY Choi, C Xie, E Chavakis, A Bierhaus, E Ihanus, CM Ballantyne, CG Gahmberg, ME Bianchi, PP Nawroth, T Chavakis: A Novel Pathway of HMGB1- Mediated Inflammatory Cell Recruitment That Requires Mac-1-Integrin. EMBO J 26, 1129-1139 (2007)
75. D Frommhold, A Kamphues, I Hepper, M Pruenster, IK Lukic, I Socher, V Zablotskaya, K Buschmann, B Lange-Sperandio, J Schymeinsky, E Ryschich, J Poeschl, C Kupatt, PP Nawroth, M Moser, B Walzog, A Bierhaus, M Sperandio: RAGE and ICAM-1 Cooperate in Mediating Leukocyte Recruitment During Acute Inflammation in vivo. Blood 116, 841-849 (2010)
76. PM Humpert, Z Djuric, S Kopf, G Rudofsky, M Morcos, PP Nawroth, A Bierhaus: Soluble RAGE but Not Endogenous Secretory RAGE Is Associated With Albuminuria in Patients With Type 2 Diabetes. Cardiovasc Diabetol 6, 9 (2007)
77. C Falcone, E Emanuele, A D'Angelo, MP Buzzi, C Belvito, M Cuccia, D Geroldi: Plasma Levels of Soluble Receptor for Advanced Glycation End Products and Coronary Artery Disease in Nondiabetic Men. Arterioscler Thromb Vasc Biol 225, 1032-1037 (2005) (Pubitemid 40627851)
78. SS Yan, ZY Wu , HP Zhang, G Furtado, X Chen, SF Yan, AM Schmidt, C Brown, A Stern, J LaFaille, L Chess, DM Stern, H Jiang: Suppression of Experimental Autoimmune Encephalomyelitis by Selective Blockade of Encephalitogenic T-Cell Infiltration of the Central Nervous System. Nat Med 9, 287-293 (2003) (Pubitemid 36362783)
79. M Neeper M, AM Schmidt, J Brett, SD Yan, F Wang, YC Pan, K Elliston, D Stern, A Shaw: Cloning and Expression of a Cell Surface Receptor for Advanced Glycosylation End Products of Proteins. J Biol Chem 267, 14998-15004 (1992)
80. MA Hofmann, S Drury, C Fu, W Qu, A Taguchi, Y Lu, C Avila, N Kambham, A Bierhaus, P Nawroth, MF Neurath, T Slattery, D Beach, J McClary, M Nagashima, J Morser, D Stern, AM Schmidt: RAGE Mediates a Novel Proinflammatory Axis: a Central Cell Surface Receptor for S100/Calgranulin Polypeptides. Cell 97, 889-901 (1999) (Pubitemid 29375048)
81. AM Schmidt, M Hofmann, A Taguchi, SD Yan, DM Stern: RAGE: a Multiligand Receptor Contributing to the Cellular Response in Diabetic Vasculopathy and Inflammation. Semin Thromb Hemost 26, 485-493 (2000)
82. D Stern, SD Yan, SF Yan, AM Schmidt: Receptor for Advanced Glycation Endproducts: a Multiligand Receptor Magnifying Cell Stress in Diverse Pathologic Settings. Adv Drug Deliv Rev 54, 1615-1625 (2002) (Pubitemid 35346835)
83. A Taguchi, DC Blood, TG del, A Canet, DC Lee, W Qu, N Tanji, Y Lu, E Lalla, C Fu, MA Hofmann, T Kislinger, M Ingram, A Lu, H Tanaka, O Hori, S Ogawa, DM Stern, AM Schmidt: Blockade of RAGE-Amphoterin Signalling Suppresses Tumour Growth and Metastases. Nature 405, 354-360 (2000) (Pubitemid 30337069)
84. F Toure, JM Zahm, R Garnotel, E Lambert, N Bonnet, AM Schmidt, F Vitry, J Chanard, P Gillery, P Rieu: Receptor for Advanced Glycation End-Products (RAGE) Modulates Neutrophil Adhesion and Migration on Glycoxidated Extracellular Matrix. Biochem J 416, 255-261 (2008)
85. JY Kim, HK Park, JS Yoon, SJ Kim, ES Kim, KS Ahn, DS Kim, SS Yoon, BK Kim, YY Lee: Advanced Glycation End Product (AGE)-Induced Proliferation of HEL Cells Via Receptor for AGE-Related S ignal Pathways. Int J Oncol 33, 493-501 (2008)
86. MA Reddy MA, SL Li, S Sahar, YS Kim, ZG Xu, L Lanting, R Natarajan: Key Role of Src Kinase in S100BInduced Activation of the Receptor for Advanced Glycation End Products in Vascular Smooth Muscle Cells. J Biol Chem 281, 13685-13693 (2006) (Pubitemid 43855284)
87. K Ishihara, K Tsutsumi, S Kawane, M Nakajima, T Kasaoka: The Receptor for Advanced Glycation End-Products (RAGE) Directly Binds to ERK by a D-Domain-Like Docking Site. FEBS Lett 550, 107-113 (2003) (Pubitemid 37281366)
88. BI Hudson, AZ Kalea, AM Del Mar, E Harja, E Boulanger, V D'Agati, AM Schmidt: Interaction of the RAGE Cytoplasmic Domain With Diaphanous-1 Is Required for Ligand-Stimulated Cellular Migration Through Activation of Rac1 and Cdc42. J Biol Chem 283, 34457-34468 (2008)
89. MF Brizzi, P Dentelli, A Rosso, C Calvi, R Gambino, M Cassader, G Salvidio, G Deferrari, G Camussi, L Pegoraro, G Pagano, P Cavallo-Perin P. FASEB J 18, 1249-1251 (2004)
90. HJ Huttunen, C Fages, H Rauvala: Receptor for Advanced Glycation End Products (RAGE)-Mediated Neurite Outgrowth and Activation of NF-KappaB Require the Cytoplasmic Domain of the Receptor but Different Downstream Signaling Pathways. J Biol Chem 274, 19919-19924 (1999)
91. E Spiekerkoetter, C Guignabert, V de JP, TP Alastalo, JM Powers, L Wang, A Lawrie, N Ambartsumian, AM Schmidt, M Berryman, RH Ashley, M Rabinovitch: S100A4 and Bone Morphogenetic Protein-2 Codependently Induce Vascular Smooth Muscle Cell Migration Via Phospho-Extracellular Signal-Regulated Kinase and Chloride Intracellular Channel 4. Circ Res 105, 639-647, 13 (2009)
92. EC Lutterloh, SM Opal, DD Pittman, JC, Jr. Keith, XY Tan, BM Clancy, H Palmer, K Milarski, Y Sun, JE Palardy, NA Parejo, N Kessimian: Inhibition ofthe RAGE Products Increases Survival in Experimental Models of Severe Sepsis and Systemic Infection. Crit Care 11, R122 (2007)
93. JA Buras, B Holzmann, M Sitkovsky: Animal Models of Sepsis: Setting the Stage. Nat Rev Drug Discov 4, 854-865 (2005) (Pubitemid 41553966)
94. MA van Zoelen, T Vogl, D Foell, SQ van Veen, JW van Till, S Florquin, MW Tanck, X Wittebole, PF Laterre, MA Boermeester, J Roth, T van der Poll: Expression and Role of Myeloid-Related Protein-14 in Clinical and Experimental Sepsis. Am J Respir Crit Care Med 180, 1098-1106 (2009)
95. MA van Zoelen, AM Schmidt, S Florquin, JC Meijers, R de Beer, AF de Vos, PP Nawroth, A Bierhaus, T van der Poll: Receptor for Advanced Glycation End Products Facilitates Host Defense During Escherichia Coli-Induced Abdominal Sepsis in Mice. J Infect Dis 200, 765-773 (2009)
96. MA van Zoelen, A Achouiti, AM Schmidt, H Yang, S Florquin, KJ Tracey, T van der Poll: Ligands of the Receptor for Advanced Glycation End Products, Including High-Mobility Group Box 1, Limit Bacterial Dissemination During Escherichia Coli Peritonitis. Crit Care Med 38, 1414-1422 (2010)
97. MA van Zoelen, H Yang, S Florquin, JC Meijers, S Akira, B Arnold, PP Nawroth, A Bierhaus, KJ Tracey, T van der Poll: Role of Toll-Like Receptors 2 and 4, and the Receptor for Advanced Glycation End Products in High-Mobility Group Box 1-Induced Inflammation in vivo. Shock 31, 280-284 (2009)
98. K Abeyama, DM Stern, Y Ito, K Kawahara, Y Yoshimoto, M Tanaka, T Uchimura, N Ida, Y Yamazaki, S Yamada, Y Yamamoto, H Yamamoto, S Iino, N Taniguchi, I Maruyama: The N-Terminal Domain of Thrombomodulin Sequesters High-Mobility Group-B1 Protein, a Novel Antiinflammatory Mechanism. J Clin Invest 115, 1267-1274 (2005) (Pubitemid 40629045)
99. JS Park, D Svetkauskaite, Q He, JY Kim, D Strassheim D, Ishizaka A, E Abraham: Involvement of Toll-Like Receptors 2 and 4 in Cellular Activation by High Mobility Group Box 1 Protein. J Biol Chem 279, 7370-7377 (2004) (Pubitemid 38294612)
100. M Yu, H Wang, A Ding, DT Golenbock, E Latz, CJ Czura, MJ Fenton, KJ Tracey, H Yang: HMGB1 Signals Through Toll-Like Receptor (TLR) 4 and TLR2. Shock 26, 174-179 (2006) (Pubitemid 44162504)
101. JS Park, F Gamboni-Robertson, Q He, D Svetkauskaite, JY Kim, D Strassheim, JW Sohn, S Yamada, I Maruyama, A Banerjee, A Ishizaka, E Abraham: High Mobility Group Box 1 Protein Interacts With Multiple Toll-Like Receptors. Am J Physiol Cell Physiol 290, C917-C924 (2006)
102. D Payen, AC Lukaszewicz, I Belikova, V Faivre, C Gelin, S Russwurm, JM Launay, N Sevenet: Gene Profiling in Human Blood Leucocytes During Recovery From Septic Shock. Intensive Care Med 34, 1371-1376 (2008)
103. D Foell, H Wittkowski, T Vogl, J Roth: S100 Proteins Expressed in Phagocytes: a Novel Group of Damage-Associated Molecular Pattern Molecules. J Leukoc Biol 81, 28-37 (2007) (Pubitemid 46021248)
104. AM Cole, YH Kim, S Tahk, T Hong, P Weis, AJ Waring, T Ganz: Calcitermin, a Novel Antimicrobial Peptide Isolated From Human Airway Secretions. FEBS Lett 504, 5-10 (2001) (Pubitemid 32777801)
105. G Fuellen, D Foell, W Nacken, C Sorg, C Kerkhoff: Absence of S100A12 in Mouse: Implications for RAGES100A12 Interaction. Trends Immunol 24, 622-624 (2003) (Pubitemid 37485909)
106. C Bopp, S Hofer, J Weitz, A Bierhaus, PP Nawroth, E Martin, MW Buchler, MA Weigand: SRAGE Is Elevated in Septic Patients and Associated With Patients Outcome. J Surg Res 147, 79-83 (2008) (Pubitemid 351626081)
107. BI Hudson, E Harja, B Moser, AM Schmidt: Soluble Levels of Receptor for Advanced Glycation Endproducts (SRAGE) and Coronary Artery Disease: the Next CReactive Protein? Arterioscler Thromb Vasc Biol 25, 879-882 (2005) (Pubitemid 40637200)
108. MA Weigand, H Schmidt, M Pourmahmoud, Q Zhao, E Martin, HJ Bardenheuer: Circulating Intercellular Adhesion Molecule-1 As an Early Predictor of Hepatic Failure in Patients With Septic Shock. Crit Care Med 27, 2656-2661 (1999) (Pubitemid 30027176)
109. T Dremsizov, G Clermont, JA Kellum, KG Kalassian, MJ Fine, DC Angus: Severe Sepsis in Community-Acquired Pneumonia: When Does It Happen, and Do Systemic Inflammatory Response Syndrome Criteria Help Predict Course? Chest 129, 968-978 (2006)
110. PF Laterre, G Garber G, H Levy, R Wunderink, GT Kinasewitz, JP Sollet, DG Maki, B Bates, SC Yan, JF Dhainaut: Severe Community-Acquired Pneumonia As a Cause of Severe Sepsis: Data From the PROWESS Study. Crit Care Med 33, 952-961 (2005) (Pubitemid 40638163)
111. JG Bartlett, SF Dowell, LA Mandell, TM File Jr, DM Musher, MJ Fine: Practice Guidelines for the Management of Community-Acquired Pneumonia in Adults. Infectious Diseases Society of America. Clin Infect Dis 31, 347-382 (2003)
112. RG Finch: Epidemiological Features and Chemotherapy of Community-Acquired Respiratory Tract Infections. J Antimicrob Chemother 26, Suppl E:53-61 (1990)
113. JG Bartlett, LM Mundy: Community-Acquired Pneumonia. N Engl J Med 333, 1618-1624 (1995)
114. MA van Zoelen, M Schouten, AF de Vos, S Florquin, JC Meijers, PP Nawroth, A Bierhaus, T van der Poll: The Receptor for Advanced Glycation End Products Impairs Host Defense in Pneumococcal Pneumonia. J Immunol 182, 4349-4356 (2009)
115. MA van Zoelen, KF van der Sluijs, A Achouiti, S Florquin, JM Braun-Pater, H Yang, PP Nawroth, KJ Tracey, A Bierhaus, T van der Poll: Receptor for Advanced Glycation End Products Is Detrimental During Influenza A Virus Pneumonia. Virology 391, 265-273 (2009)
116. L Lin: RAGE on the Toll Road? Cell Mol Immunol 3, 351-358 (2006)
117. J Dushoff, JB Plotkin, C Viboud, DJ Earn, L Simonsen: Mortality Due to Influenza in the United States - an Annualized Regression Approach Using Multiple-Cause Mortality Data. Am J Epidemiol 163, 181-187 (2006) (Pubitemid 43068987)
118. C Dye, S Scheele, P Dolin, V Pathania, MC Raviglione: Consensus Statement. Global Burden of Tuberculosis: Estimated Incidence, Prevalence, and Mortality by Country. WHO Global Surveillance and Monitoring Project. JAMA 282, 677-686 (1999)
119. SH Kaufmann: How Can Immunology Contribute to the Control of Tuberculosis? Nat Rev Immunol 1, 20-30 (2001) (Pubitemid 33741972)