RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo

Blood

Volumn 116, Issue 5, 2010, Pages 841-849

  Frommhold, David ^a   Kamphues, Anna ^a   Hepper, Ingrid ^b   Pruenster, Monika ^b   Lukić, Ivan K ^a,c   Socher, Ines ^b   Zablotskaya, Victoria ^a   Buschmann, Kirsten ^a   Lange Sperandio, Baerbel ^b   Schymeinsky, Jürgen ^b   Ryschich, Eduard ^a   Poeschl, Johannes ^a   Kupatt, Christian ^d   Nawroth, Peter P ^a   Moser, Markus ^e   Walzog, Barbara ^b   Bierhaus, Angelika ^a   Sperandio, Markus ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c Biosistemi doo   (Croatia)

^d UNIVERSITY OF MUNICH   (Germany)

^e MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; BETA2 INTEGRIN; CD11B ANTIGEN; CXCL1 CHEMOKINE; FIBRINOGEN; INTERCELLULAR ADHESION MOLECULE 1; PADGEM PROTEIN; HYBRID PROTEIN; LEUKOTRIENE B4; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; RAGE PROTEIN, MOUSE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL TISSUE; ARTICLE; CELL MOTILITY; CHIMERA; CONTROLLED STUDY; CREMASTER MUSCLE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INFLAMMATION; INJURY; LEUKOCYTE; LEUKOCYTE ADHERENCE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; ACUTE DISEASE; ANIMAL; CELL ADHESION; CELL SHAPE; DRUG EFFECT; HUMAN; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PHYSIOLOGY; RADIATION CHIMERA; SKELETAL MUSCLE; VASCULAR ENDOTHELIUM; VASCULARIZATION; VASCULITIS; VENULE;

ACUTE DISEASE; ANIMALS; CELL ADHESION; CELL SHAPE; CHEMOTAXIS, LEUKOCYTE; ENDOTHELIUM, VASCULAR; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LEUKOTRIENE B4; LIGANDS; MACROPHAGE-1 ANTIGEN; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SKELETAL; NEUTROPHILS; RADIATION CHIMERA; RECOMBINANT FUSION PROTEINS; TUMOR NECROSIS FACTOR-ALPHA; VASCULITIS; VENULES;

EID: 77956277999     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-09-244293     Document Type: Article

References (41)

1. Springer TA. Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Annu Rev Physiol. 1995;57:827-872.
2. Ley K, Laudanna C, Cybulsky MI, Nourshargh S. Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat Rev Immunol. 2007;7(9):678-689. (Pubitemid 47327397)
3. Laudanna C, Alon R. Right on the spot: chemokine triggering of integrin-mediated arrest of rolling leukocytes. Thromb Haemost. 2006;95(1):5-11.
4. Schymeinsky J, Mocsai A, Walzog B. Neutrophil activation via beta2 integrins (CD11/CD18): molecular mechanisms and clinical implications. Thromb Haemost. 2007;98(2):262-273.
5. Ryschich E, Kerkadze V, Lizdenis P, et al. Active leukocyte crawling in microvessels assessed by digital time-lapse intravital microscopy. J Surg Res. 2006;135(2):291-296.
6. Phillipson M, Heit B, Colarusso P, et al. Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade. J Exp Med. 2006;203(12): 2569-2575.
7. Hirahashi J, Mekala D, Van Ziffle J, et al. Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy. Immunity. 2006;25(2):271-283.
8. Frommhold D, Mannigel I, Schymeinsky J, et al. Syk is critical for sustained leukocyte adhesion during inflammation in vivo. BMC Immunol. 2007; 8(31):1-8.
9. Schymeinsky J, Sindrilaru A, Frommhold D, et al. The Vav binding site of the non-receptor tyrosine kinase Syk at Tyr 348 is critical for beta2integrin (CD11/CD18)-mediated neutrophil migration. Blood. 2006;108(12):3919-3927.
10. Lange-Sperandio B, Sperandio M, Nawroth P, Bierhaus A. RAGE signaling in cell adhesion and inflammation. Curr Ped Rev. 2007;3(1):1-9.
11. Bierhaus A, Schiekofer S, Schwaninger M, et al. Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB. Diabetes. 2001;50(12):2792-2808. (Pubitemid 33733131)
12. Bierhaus A, Humpert PM, Morcos M, et al. Understanding RAGE, the receptor for advanced glycation end products. J Mol Med. 2005;83(11):876-886.
13. Chavakis T, Bierhaus A, Al Fakhri N, et al. The pattern recognition receptor (RAGE) is a counter-receptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment. J Exp Med. 2003;198(10):1507-1515.
14. Orlova VV, Choi EY, Xie C, et al. A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin. EMBO J. 2007;26(4):1129-1139. (Pubitemid 46303578)
15. Zen K, Chen CX, Chen YT, Wilton R, Liu Y. Receptor for advanced glycation endproducts mediates neutrophil migration across intestinal epithelium. J Immunol. 2007;178(4):2483-2490. (Pubitemid 46233449)
16. Liliensiek B, Weigand MA, Bierhaus A, et al. Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response. J Clin Invest. 2004;113(11): 1641-1650.
17. Xu H, Gonzalo JA, St Pierre Y, et al. Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice. J Exp Med. 1994;180(1):95-109.
18. Faust N, Varas F, Kelly LM, Heck S, Graf T. Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages. Blood. 2000;96(2):719-726.
19. Yakubenia S, Frommhold D, Schölch D, et al. Leukocyte trafficking in a mouse model for leukocyte adhesion deficiency II/congenital disorder of glycosylation IIc. Blood. 2008;112(4):1472-1481.
20. Sperandio M, Frommhold D, Babushkina I, et al. α2,3- Sialyltransferase-IV is essential for L-selectin ligand function in inflammation. Eur J Immunol. 2006;36(12):3207-3215.
21. Lehr H-A, Guhlmann A, Nolte D, Keppler D, Messmer K. Leukotrienes as mediators in ischemia-reperfusion injury in a microcirculation model in the hamster. J Clin Invest. 1991;87(6): 2036-2041.
22. Coxon A, Rieu P, Barkalow FJ, et al. A novel role for the beta-2 integrin CD11b/CD18 in neutrophil apoptosis: a homeostatic mechanism in inflammation. Immunity. 1996;5(6):653-666.
23. Sperandio M, Thatte A, Foy D, et al. Severe impairment of leukocyte rolling in venules of core 2 glucosaminyltransferase-deficient mice. Blood. 2001;97(12):3812-3819.
24. Smith ML, Sperandio M, Galkina EV, Ley K. Autoperfused mouse flow chamber reveals synergistic neutrophil accumulation through P-selectin and E-selectin. J Leukoc Biol. 2004;76(5):985-993.
25. Frommhold D, Ludwig A, Bixel MG, et al. Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation. J Exp Med. 2008;205(6):1435-1446. (Pubitemid 351831498)
26. Spring H, Schuler T, Arnold B, Hammerling GJ, Ganss R. Chemokines direct endothelial progenitors into tumor neovessels. Proc Natl Acad Sci U S A. 2005;102(50):18111-18116.
27. Jung U, Ley K. Regulation of E-selectin, P-selectin and ICAM-1 expression in mouse cremaster muscle vasculature. Microcirculation. 1997;4(2):311-319.
28. Henderson RB, Lim LH, Tessier PA, et al. The use of lymphocyte function-associated antigen (LFA)-1-deficient mice to determine the role of LFA-1, Mac-1, and alpha4 integrin in the inflammatory response of neutrophils. J Exp Med. 2001;194(2):219-226.
29. Seo SM, McIntire LV, Smith CW. Effects of IL-8, Gro-alpha, and LTB(4) on the adhesive kinetics of LFA-1 and Mac-1 on human neutrophils. Am J Physiol Cell Physiol. 2001;281(5):C1568-C1578.
30. van Pelt JP, de Jong EM, van Erp PE, et al. The regulation of CD11b integrin levels on human blood leukocytes and leukotriene B4-stimulated skin by a specific leukotriene B4 receptor antagonist (LY293111). Biochem Pharmacol. 1997; 53(7):1005-1012.
31. Dunne JL, Collins RG, Beaudet AL, Ballantyne CM, Ley K. Mac-1, but not LFA-1, uses intercellular adhesion molecule-1 to mediate slow leukocyte rolling in TNF-alpha-induced inflammation. J Immunol. 2003;171(11):6105-6111.
32. Lin L, Park S, Lakatta EG. RAGE signaling in inflammation and arterial aging. Front Biosci. 2009; 14:1403-1413.
33. Dunne JL, Ballantyne CM, Beaudet AL, Ley K. Control of leukocyte rolling velocity in TNF-alpha-induced inflammation by LFA-1 and Mac-1. Blood. 2002;99(1):336-341.
34. Forlow SB, White EJ, Barlow SC, et al. Severe inflammatory defect and reduced viability in CD18 and E-selectin double-mutant mice. J Clin Invest. 2000;106(12):1457-1466.
35. Yang L, Froio RM, Sciuto TE, et al. ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow. Blood. 2005;106(2):584-592. (Pubitemid 40981255)
36. Wong J, Johnston B, Lee SS, et al. A minimal role for selectins in the recruitment of leukocytes into the inflamed liver microvasculature. J Clin Invest. 1997;99(11):2782-2790. (Pubitemid 27259826)
37. Pullerits R, Brisslert M, Jonsson IM, Tarkowski A. Soluble receptor for advanced glycation end products triggers a proinflammatory cytokine cascade via beta2 integrin Mac-1. Arthritis Rheum. 2006;54(12):3898-3907. (Pubitemid 44955893)
38. Phillipson M, Heit B, Parsons SA, et al. Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculature. J Immunol. 2009;182(11):6870-6878.
39. Fagerholm SC, Varis M, Stefanidakis M, Hilden TJ, Gahmberg CG. α-Chain phosphorylation of the human leukocyte CD11b/CD18 (Mac-1) integrin is pivotal for integrin activation to bind ICAMs and leukocyte extravasation. Blood. 2006; 108(10):3379-3386.
40. Giri R, Shen Y, Stins M, et al. β-Amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE an1d PECAM-1. Am J Physiol Cell Physiol. 2000;279(6):C1772-C1781.
41. Giri R, Selvaraj S, Miller CA, et al. Effect of endothelial cell polarity on beta-amyloid-induced migration of monocytes across normal and AD endothelium. Am J Physiol Cell Physiol. 2002; 283(3):C895-C904.