Blockade of the receptor for advanced glycation end products attenuates acetaminophen-induced hepatotoxicity in mice

Journal of Gastroenterology and Hepatology (Australia)

Volumn 21, Issue 4, 2006, Pages 682-688

  Ekong, Udeme ^a   Zeng, Shan ^a   Dun, Hao ^a   Feirt, Nikki ^a   Guo, Jiancheng ^a   Ippagunta, Nikalesh ^a   Guarrera, James V ^a   Lu, Yan ^a   Weinberg, Alan ^a   Qu, Wu ^a   Ramasamy, Ravichandran ^a   Schmidt, Ann Marie ^a   Emond, Jean C ^a  

^a Department of Pediatrics College of Physicians and Surgeons Columbia University ^*  (United States)

Author keywords

Acetaminophen; Cytokines; Hepatotoxicity; Mice; Receptor for advanced glycation end products (RAGE)

Indexed keywords

3 NITROTYROSINE; ADVANCED GLYCATION END PRODUCT RECEPTOR; CYTOKINE; GLUTATHIONE; INTERLEUKIN 6; PARACETAMOL; REACTIVE OXYGEN METABOLITE; RECEPTOR BLOCKING AGENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SOLUBLE ADVANCED GLYCATION END PRODUCT RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; COMPARATIVE STUDY; CONTROLLED STUDY; DOWNSTREAM PROCESSING; LIGAND BINDING; LIVER INJURY; LIVER NECROSIS; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION;

EID: 33645892294     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2006.04225.x     Document Type: Article

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