Molecular imaging in tumor angiogenesis and relevant drug research

International Journal of Biomedical Imaging

Volumn 2011, Issue , 2011, Pages

  Tian, Jie ^a   Ma, Xibo ^a   Yang, Xin ^a   Qin, Chenghu ^a  

^a INSTITUTE OF AUTOMATION   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANATOMIC INFORMATION; BIOLUMINESCENCE IMAGING; COMPUTED TOMOGRAPHY; DEVELOPMENT PROCESS; DRUG DEVELOPMENT; DRUG RESEARCH; FLUORESCENCE IMAGING; FUNCTIONAL INFORMATION; MICRO CT; MOLECULAR IMAGING; OPTICAL INFORMATION; REGION OF INTEREST; TUMOR ANGIOGENESIS;

MULTIPHOTON PROCESSES; POSITRON EMISSION TOMOGRAPHY; RESEARCH; TUMORS;

SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY;

EID: 80052671278     PISSN: 16874188     EISSN: 16874196     Source Type: Journal    
DOI: 10.1155/2011/370701     Document Type: Review

References (69)

1. Willmann J. K., Bruggen N., Dinkelborg L. M., Gambhir S. S., Molecular imaging in drug development Nature Reviews Drug Discovery 2008 7 7 591 606
2. Hargreaves R. J., The role of molecular imaging in drug discovery and development Clinical Pharmaclology Therapeutics 2007 82 2 349 353
3. Iagaru A., Chen X., Gambhir S. S., Molecular imaging can accelerate anti-angiogenic drug development and testing Nature Clinical Practice Oncology 2007 4 10 556 557 (Pubitemid 47534751)
4. Hanahan D., Weinberg R. A., The hallmarks of cancer Cell 2000 100 1 57 70 (Pubitemid 30046295)
5. Cai W., Rao J., Gambhir S. S., Chen X., How molecular imaging is speeding up antiangiogenic drug development Molecular Cancer Therapeutics 2006 5 11 2624 2633 (Pubitemid 44848989)
6. Ma X. B., Liu Z. F., Yang X., Dual-modality monitoring of tumor response to cyclophosphamide therapy in mice with bioluminescence imaging and small-animal positron emission tomography Molecular Imaging 2011 10 4 278 283
7. Prenen H., Stefan C., Oosterom A., Imatinib mesylate inhibits glucose uptake in gastrointestinal stromal tumor cells by downregulation of the glucose transporters recruitment to the plasma membrane American Journal of Biochemistry and Biotechnology 2005 1 2 95 102
8. Luker G. D., Luker K. E., Optical imaging: current applications and future directions Journal of Nuclear Medicine 2008 49 1 1 4
9. Luker K. E., Piwnica-Worms D., Optimizing luciferase protein fragment complementation for bioluminescent imaging of protein-protein interactions in live cells and animals Methods in Enzymology 2004 385 349 360 (Pubitemid 38656336)
10. Massoud T. F., Paulmurugan R., Ray P., Gambhir S. S., Reporter gene imaging of protein-protein interactions in living subjects Current Opinion in Biotechnology 2007 18 1 31 37 (Pubitemid 46227972)
11. Massoub T. F., Paulmurugan R., Gambhir S. S., Molecular imaging of homodimeric protein-protein interactions in living subjects Federation of American Societies for Experimental Biology Journal 2004 18 10 1105 1107 (Pubitemid 39561538)
12. Paulmurugan R., Gambhir S. S., An intramolecular folding sensor for imaging estrogen receptor-ligand interactions Proceedings of the National Academy of Sciences of the United States of America 2006 103 43 15883 15888 (Pubitemid 44657561)
13. Paulmurugan R., Gambhir S. S., Combinatorial library screening for developing an improved split-firefly luciferase fragment-assisted complementation system for studying protein-protein interactions Analytical Chemistry 2007 79 6 2346 2353 (Pubitemid 46449015)
14. Paulmurugan R., Massoud T. F., Huang J., Gambhir S. S., Molecular imaging of drug-modulated protein-protein interactions in living subjects Cancer Research 2004 64 6 2113 2119 (Pubitemid 38339461)
15. Paulmurugan R., Ray P., De A., Chan C. T., Gambhir S. S., Golemis E., Adams P. D., Imaging protein-protein interactions in living animals ProteinProtein Interactions: A Molecular Cloning Manual 2005 1 2nd New York, NY, USA Cold Spring Harbor Laboratory Press 695 713
16. Paulmurugan R., Ray P., De A., Chan C. T., Gambhir S. S., Imaging protein-protein interactions in living subjects Trends in Analytical Chemistry 2005 24 5 446 458 (Pubitemid 40615873)
17. Paulmurugan R., Umezawa Y., Gambhir S. S., Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies Proceedings of the National Academy of Sciences of the United States of America 2002 99 24 15608 15613 (Pubitemid 35407485)
18. Luker G. D., Sharma V., Piwnica D. W., Visualizing protein-protein interactions in living animals Methods 2003 29 1 110 122 (Pubitemid 36259917)
19. Villalobos V., Naik S., Piwnica-Worms D., Current state of imaging protein-protein interactions in vivo with genetically encoded reporters Annual Review of Biomedical Engineering 2007 9 321 349 (Pubitemid 350246660)
20. Paulmurugant R., Gambhir S. S., Monitoring protein-protein interactions using split synthetic renilla luciferase protein-fragment-assisted complementation Analytical Chemistry 2003 75 7 1584 1589 (Pubitemid 36512595)
21. Luker K. E., Smith M. C. P., Luker G. D., Gammon S. T., Piwnica-Worms H., Piwnica-Worms D., Kinetics of regulated protein-protein interactions revealed with firefly luciferase complementation imaging in cells and living animals Proceedings of the National Academy of Sciences of the United States of America 2004 101 33 12288 12293 (Pubitemid 39145436)
22. Paulmurugan R., Gambhir S. S., Novel fusion protein approach for efficient high-throughput screening of small molecule-mediating protein-protein interactions in cells and living animals Cancer Research 2005 65 16 7413 7420 (Pubitemid 41161275)
23. Remy I., Michnick S. W., A highly sensitive protein-protein interaction assay based on Gaussia luciferase Nature Methods 2006 3 12 977 979 (Pubitemid 44782695)
24. Luker G. D., Pica C. M., Song J., Luker K. E., Piwnica-Worms D., Imaging 26S proteasome activity and inhibition in living mice Nature Medicine 2003 9 7 969 973 (Pubitemid 36889943)
25. Zhang G. J., Safran M., Wei W., Sorensen E., Lassota P., Zhelev N., Neuberg D. S., Shapiro G., Kaelin W. G., Bioluminescent imaging of Cdk2 inhibition in vivo Nature Medicine 2004 10 6 643 648 (Pubitemid 38796857)
26. Safran M., Kim W. Y., O'Connell F., Flippin L., Gnzler V., Horner J. W., DePinho R. A., Kaelin W. G., Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production Proceedings of the National Academy of Sciences of the United States of America 2006 103 1 105 110 (Pubitemid 43076112)
27. Funovics M., Weissleder R., Tung C. H., Protease sensors for bioimaging Analytical and Bioanalytical Chemistry 2003 377 6 956 963 (Pubitemid 40877826)
28. Grimm J., Kirsch D. G., Windsor S. D., Kim C. F. B., Santiago P. M., Ntziachristos V., Jacks T., Weissleder R., Use of gene expression profiling to direct in vivo molecular imaging of lung cancer Proceedings of the National Academy of Sciences of the United States of America 2005 102 40 14404 14409 (Pubitemid 41429710)
29. Jiang T., Olson E. S., Nguyen Q. T., Roy M., Jennings P. A., Tsien R. Y., Tumor imaging by means of proteolytic activation of cell-penetrating peptides Proceedings of the National Academy of Sciences of the United States of America 2004 101 51 17867 17872 (Pubitemid 40051978)
30. Tian J., Xue J., Dai Y., Chen J., Zheng J., A novel software platform for medical image processing and analyzing IEEE Transactions on Information Technology in Biomedicine 2008 12 6 800 812
31. Lv Y., Tian J., Cong W., Wang G., Luo J., Yang W., Li H., A multilevel adaptive finite element algorithm for bioluminescence tomography Optics Express 2006 14 18 8211 8223 (Pubitemid 44331037)
32. Gambhir S. S., Molecular imaging of cancer with positron emission tomography Nature Reviews Cancer 2002 2 9 683 693 (Pubitemid 37328919)
33. Bombardieri E., The added value of metabolic imaging with FDG-PET in oesophageal cancer: prognostic role and prediction of response to treatment European Journal of Nuclear Medicine and Molecular Imaging 2006 33 7 753 758 (Pubitemid 43979682)
34. Belhocine T., Steinmetz N., Hustinx R., Bartsch P., Jerusalem G., Seidel L., Rigo P., Green A., Increased uptake of the apoptosis-imaging agent (99 m) Tc recombinant human annexin V in human tumors after one course of chemotherapy as a predictor of tumor response and patient prognosis Clinical Cancer Research 2002 8 9 2766 2774 (Pubitemid 35025718)
35. Boersma H. H., Kietselaer B. L. J. H., Stolk L. M. L., Bennaghmouch A., Hofstra L., Narula J., Heidendal G. A. K., Reutelingsperger C. P. M., Past, present, and future of annexin A5: from protein discovery to clinical applications Journal of Nuclear Medicine 2005 46 12 2035 2050 (Pubitemid 46657451)
36. Wang L., Shi J., Kim Y. S., Zhai S., Jia B., Zhao H., Liu Z., Wang F., Chen X., Liu S., Improving tumor-targeting capability and pharmacokinetics of 99 Tc -labeled cyclic RGD dimers with PEG4 linkers Molecular Pharmaceutics 2009 6 1 231 245
37. Cherry S. R., In vivo molecular and genomic imaging: new challenges for imaging physics Physics in Medicine and Biology 2004 49 3 R13 R48
38. Feldkamp L. A., Davis L. C., Kress J. W., Practical cone-beam algorithm Journal of the Optical Society of America A 1984 1 6 612 619
39. Ritman E. L., Molecular imaging in small animals roles for micro-CT Journal of Cellular Biochemistry 2002 39 116 124 (Pubitemid 36181517)
40. Ferrara N., VEGF and the quest for tumour angiogenesis factors Nature Reviews Cancer 2002 2 10 795 803 (Pubitemid 37328914)
41. Izzo A. D., Mackanos M. A., Beckham J. T., Jansen E. D., In vivo optical imaging of expression of vascular endothelial growth factor following laser incision in skin Lasers in Surgery and Medicine 2001 29 4 343 350 (Pubitemid 33022074)
42. Wang Y., Iyer M., Annala A., Wu L., Carey M., Gambhir S. S., Noninvasive indirect imaging of vascular endothelial growth factor gene expression using bioluminescence imaging in living transgenic mice Physiological Genomics 2006 24 2 173 180
43. Hsu A. R., Cai W. B., Veeravagu A., Mohamedali K. A., Chen K., Kim S., Vogel H., Hou L. C., Tse V., Rosenblum M. G., Chen X. Y., Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF121/rGel Journal of Nuclear Medicine 2007 48 3 445 454 (Pubitemid 47604931)
44. Cherry S. R., Shao Y., Silverman R. W., Meadors K., Siegel S., Chatziioannou A., Young J. W., Jones W. F., Moyers J. C., Newport D., Boutefnouchet A., Farquhar T. H., Andreaco M., Paulus M. J., Binkley D. M., Nutt R., Phelps M. E., MicroPET: a high resolution PET scanner for imaging small animals IEEE Transactions on Nuclear Science 1997 44 3 1161 1166 (Pubitemid 127827067)
45. Chatziioannou A. F., Cherry S. R., Shao Y., Silverman R. W., Meadors K., Farquhar T. H., Pedarsani M., Phelps M. E., Performance evaluation of microPET: a high-resolution lutetium oxyorthosilicate PET scanner for animal imaging Journal of Nuclear Medicine 1999 40 7 1164 1175 (Pubitemid 29315509)
46. Collingridge D. R., Carroll V. A., Glaser M., Aboagye E. O., Osman S., Hutchinson O. C., Barthel H., Luthra S. K., Brady F., Bicknell R., Price P., Harris A. L., The development of [ 124 I ]iodinated-VG76e: a novel tracer for imaging vascular endothelial growth factor in vivo using positron emission tomography Cancer Research 2002 62 20 5912 5919 (Pubitemid 35204754)
47. Cai W., Chen K., Mohamedali K. A., Cao Q., Gambhir S. S., Rosenblum M. G., Chen X., PET of vascular endothelial growth factor receptor expression Journal of Nuclear Medicine 2006 47 12 2048 2056 (Pubitemid 47544993)
48. Hsu A. R., Cai W., Veeravagu A., Mohamedali K. A., Chen K., Kim S., Vogel H., Hou L. C., Tse V., Rosenblum M. G., Chen X., Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF 121 /rGel Journal of Nuclear Medicine 2007 48 3 445 454 (Pubitemid 47604931)
49. Lu E., Wagner W. R., Schellenberger U., Abraham J. A., Klibanov A. L., Woulfe S. R., Csikari M. M., Fischer D., Schreiner G. F., Brandenburger G. H., Villanueva F. S., Targeted in vivo labeling of receptors for vascular endothelial growth factor: approach to identification of ischemic tissue Circulation 2003 108 1 97 103 (Pubitemid 36859027)
50. Backer M. V., Levashova Z., Patel V., Jehning B. T., Claffey K., Blankenberg F. G., Backer J. M., Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes Nature Medicine 2007 13 4 504 509 (Pubitemid 46559824)
51. Blankenberg F. G., Mandl S., Cao Y. A., O'Connell-Rodwell C., Contag C., Mari C., Gaynutdinov T. I., Vanderheyden J. L., Backer M. V., Backer J. M., Tumor imaging using a standardized radiolabeled adapter protein docked to vascular endothelial growth factor Journal of Nuclear Medicine 2004 45 8 1373 1380 (Pubitemid 47618538)
52. Liu Z., Wang F., Chen X., Integrin v 3-targeted cancer therapy Drug Development Research 2008 69 6 329 339
53. Jia B., Shi J., Yang Z., Xu B., Liu Z., Zhao H., Liu S., Wang F., 99 Tc -labeled cyclic RGDfK dimer: initial evaluation for SPECT imaging of glioma integrin v 3 expression Bioconjugate Chemistry 2006 17 4 1069 1076 (Pubitemid 44162628)
54. He Q., Liu Z., Jia B., Li X., Shi J., Zhang J., Lan F., Yang Z., Liu Y., Shen L., Wang F., In vivo gamma imaging of the secondary tumors of transplanted human fetal striatum neural stem cells-derived primary tumor cells NeuroReport 2008 19 10 1009 1014
55. Liu Z., Liu S., Wang F., Lieu S., Chen X., Noninvasive imaging of tumor integrin expression using 18 F-labeled RGD dimer peptide with PEG4 linkers European Journal of Nuclear Medicine and Molecular Imaging 2009 36 8 1296 1307
56. Liu S., Liu Z., Chen K., Yan Y., Watzlowik P., Wester H. J., Chin F. T., Chen X., 18 F -labeled galacto and PEGylated RGD dimers for PET imaging of v 3 integrin expression Molecular Imaging and Biology 2010 12 5 530 538
57. Liu Z. F., Niu G., Shi J., 68 Ga -labeled cyclic RGD dimmers with Gly 3 PEG 4 linkers: promising agents for tumor integrin v 3 PET imaging European Journal of Nuclear Medicine and Molecular Imaging 2010 36 947 957
58. Cao F., Li Z., Lee A., Liu Z., Chen K., Wang H., Weibo C., Chen X., Wu J. C., Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation Cancer Research 2009 69 7 2709 2713
59. Veeravagu A., Liu Z., Niu G., Chen K., Jia B., Cai W., Jin C., Hsu A. R., Connolly A. J., Tse V., Wang F., Chen X., Integrin v 3 -targeted radioimmunotherapy of glioblastoma multiforme Clinical Cancer Research 2008 14 22 7330 7339
60. Liu Z. F., Jia B., Zhao H. Y., Chen X. Y., Wang F., Specific targeting of human integrin v 3 with 111 In -labeled abegrin TM in nude mouse models Molecular Imaging and Biology 2011 13 1 112 120
61. Liu Z., Liu S., Niu G., Wang F., Chen X., Optical imaging of integrin v 3 expression with near- infrared fluorescent RGD dimer with tetra(ethylene glycol) linkers Molecular Imaging 2010 9 1 21 29
62. Hood J. D., Cheresh D. A., Role of integrins in cell invasion and migration Nature Reviews Cancer 2002 2 2 91 100 (Pubitemid 37328796)
63. Xiong J. P., Stehle T., Zhang R., Joachimiak A., Frech M., Goodman S. L., Arnaout M. A., Crystal structure of the extracellular segment of integrin v 3 in complex with an Arg-Gly-Asp ligand Science 2002 296 5565 151 155 (Pubitemid 34280076)
64. Cai W., Chen X., Anti-angiogenic cancer therapy based on integrin v 3 antagonism Anti-Cancer Agents in Medicinal Chemistry 2006 6 5 407 428
65. Xiong J. P., Stehle T., Diefenbach B., Zhang R., Dunker R., Scott D. L., Joachimiak A., Goodman S. L., Arnaout M. A., Crystal structure of the extracettutar segment of integrin v 3 Science 2001 294 5541 339 345 (Pubitemid 32963395)
66. Cai W., Gambhir S. S., Chen X., Multimodality tumor imaging targeting integrin v 3 BioTechniques 2005 39 6 S14 S25
67. Achilefu S., Bloch S., Markiewicz M. A., Zhong T., Ye Y. P., Dorshow R. B., Chance B., Liang K., Synergistic effects of light-emitting probes and peptides for targeting and monitoring integrin expression Proceedings of the National Academy of Sciences of the United States of America 2005 102 22 7976 7981 (Pubitemid 40781048)
68. Ye Y., Bloch S., Xu B., Achilefu S., Design, synthesis, and evaluation of near infrared fluorescent multimeric RGD peptides for targeting tumors Journal of Medicinal Chemistry 2006 49 7 2268 2275
69. Ma X. B., Tian J., Qin C. H., Early detection of liver cancer based on bioluminescent tomography Applied Optics 2011 50 10 1389 1395