MicroPET: A high resolution PET scanner for imaging small animals

IEEE Transactions on Nuclear Science

Volumn 44, Issue 3 PART 2, 1997, Pages 1161-1166

  Cherry, S R ^a,b   Shao, Y ^a   Silverman, R W ^a   Meadors, K ^a   Siegel, S ^a   Chatziioannou, A ^a   Young, J W ^a,b   Jones, W F ^a   Moyers, J C ^b   Newport, D ^b   Boutefnouchet, A ^b   Farquhar, T H ^b   Andreaco, M ^a,b   Paulus, M J ^a   Binkley, D M ^a   Nutt, R ^a   Phelps, M E ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CTI PET Systems Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 34648840245     PISSN: 00189499     EISSN: None     Source Type: Journal    
DOI: 10.1109/23.596981     Document Type: Article

References (26)

1. R.D. Hichwa, "Are animal scanners really necessary for PET," J Nucl Med, vol. 35, pp. 1396-1397, 1994.
2. M. Watanabe, H. Uchida, H. Okada et al, "A high resolution PET for animal studies," IEEE Trans Med Imag vol. 11, pp. 577-580, 1992.
3. RM. Bloomfield, S. Rajeswaran, S., T.J. Spinks et al, "The design and physical characteristics of a small animal positron emission tomograph," Phys Med Biol, vol. 40, pp. 1105-26, 1995.
4. R. Lecomte, J. Cadorette, S. Rodrique et al, "Initial results from the Sherbrooke Avalanche Photodiode Positron Tomograph," IEEE Trans Nucl Sei, vol. 43, pp. 1952-1957, ; 1996.
5. ! S. Zhang, P. Bruyndonckx, M.B. Goldberg, S. Tavernier. "Study of a high resolution 3D PET Scanner," Nucl Inst Meth, vol. A348, pp. 607-612, 1994.
6. M. Watanabe, T. Omura, H. Kyushima, Y. Hasegawa, T. Yamashita, "A compact position-sensitive detector for PET" IEEE Trans Nuc Sei vol. NS-42, pp. 1090-1094, 1995.
7. S. Weber, A. Terstegge, H. Hailing et al, "The design of an animal PET: Flexible geometry for achieving optimal spatial resolution or high sensitivity, in: Conference Record of the IEEE Nuclear Science and Medical Imaging Conference, San Francisco, CA, pp. 1002-1005, 1995.
8. J. Seidel, W.R. Gandler, M.V. Green, "A very high resolution single slice small animal PET scanner based on direct detection of coincidence line endpoints," J Nucl Med, vol. 35, pp. 40P, 1994.
9. C. Schmelz, S.M. Bradbury, I. Holl et al, "Feasibility study of an avalanche photodiode readout for a high resolution PET with nsec time resolution," IEEE Trans Nucl Sei, vol. NS42, pp. 1080-1084, 1995.
10. S.R. Cherry, Shao Y, Siegel S et al, " Optical fiber readout of scintillator arrays using a multi-channel PMT: A high resolution PET detector for animal imaging," IEEE Trans Nucl Sei vol. 43, pp. 1932-1937, 1996.
11. P.D. Cutler, S.R. Cherry, E.J. Hoffman, W.M. Digby, M.E. Phelps, "Design features and performance of a PET system for animal research," J Nucl Med, vol. 33, pp. 595-604, 1992.
12. J.R. Barrio, S-C Huang, D.C. Yu et al, "Radiofluorinated Lm-Tyrosines: New in-vivo probes for central dopamine biochemistry," J. Cereb Blood Flow Metab, vol. 16, pp 667-678, 1996.
13. M.J. Raleigh, W.P. Melega, A. Moore et al, "FDG PET studies of neural development in conscious infant primates," J Nucl Med, vol. 37, pp. 55P, 1996.
14. A. Srinivasan, S.S. Gambhir, A.L. Green et al, "A PET reporter gene/PET reporter probe technology for repeatedly imaging gene expression in living animals," J Nucl Med, vol. 37, pp. 107P, 1996.
15. S.R. Cherry, Y. Shao, M.P. Tornai et al, "Collection of scintillation light from small BGO crystals," IEEE Trans Nucl Sei, vol. 42, pp. 1058-1063, 1995.
16. B. Baumbaugh, J. Erdman, D. Gaskell, et al "Performance of multiclad scintillating and clear waveguide fibers read out with visible light photon counters," Nucl Inst Meth, vol, A345, pp. 271-278, 1994.
17. G. Comby, and R. Meunier, "Test of a new 64 channel PMT for imaging," Nucl Inst Meth, vol. A269, pp. 246-260, 1988.
18. S. Majewski, B. Kross, R. Wojcik, A. Weisenberger, and Zorn C, "Studies of position sensitive photomultipliers in readout of scintillating and waveshifting fibers," Nucl Inst Meth, vol. A323, pp.,489-504, 1992.
19. Y. Shao, S.R. Cherry, S. Siegel, R.W. Silverman. "Evaluation of multi-channel PMT's for readout of scintillator arrays," Nucl Inst Meth, accepted for publication, 1996.
20. S. Siegel, R.W. Silverman, Y. Shao, S.R. Cherry. "Simple charge division readouts for imaging scintillator arrays using a multi-channel PMT," IEEE Trans Nucl Sei, vol. 43, pp. 1932-1937, 1996.
21. M.E. Casey and R. Nutt, "A multicrystal two dimensional BGO detector system for positron emission tomography, "IEEE Trans Nucl Sei, vol. 33, pp. 460-463, 1986.
22. S.R. Cherry, M.P. Tornai, C.S. Levin et al, "A comparison of PET detector modules employing rectangular and round photomultiplier tubes," IEEE Trans Nucl Sei vol. 42, pp. 1064-1068, 1995.
23. P.D. Cutler, E.J. Huffman, "Use of digital front-end electronics for optimization of a modular PET detector," IEEE Trans Med Imag, vol 13. pp 408-418, 1994.
24. P.E. Kinahan, J.G. Rogers, "Analytic 3D image reconstruction using all detected events," IEEE Trans Nucl Sei, vol. 36, pp. 964-968, 1989.
25. EJ. Hoffman, P.D. Cutler, W.M. Digby, J.C. Mazziotta, "3D phantom to simulate cerebral blood flow and metabolic images for PET," IEEE Trans Nucl Sei, vol. 37, pp. 616-620, 1990.
26. E.U. Mumcuoglu, R.M. Leahy, S.R. Cherry, "Bayesian reconstruction of PET images: methodology and performance analysis," Phys Med Biol, vol. 41, pp. 17771807.