메뉴 건너뛰기




Volumn 13, Issue 1, 2011, Pages 112-120

Specific targeting of human integrin αvβ3 with 111in-labeled abegrin™ in nude mouse models

Author keywords

111In; Abegrin ; Imaging; Integrin v 3; Tumor

Indexed keywords

1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; ETARACIZUMAB; ETARACIZUMAB 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID IN 111; FLUORESCEIN ISOTHIOCYANATE; GADOTERIC ACID; INDIUM 111; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

EID: 79551598150     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-010-0302-4     Document Type: Article
Times cited : (22)

References (39)
  • 1
    • 33645811072 scopus 로고    scopus 로고
    • Integrins in cancer treatment
    • 1:CAS:528:DC%2BD28XislSmsLk%3D 10.2174/156800906776056518 16529540
    • JA Eble J Haier 2006 Integrins in cancer treatment Curr Cancer Drug Targets 6 89 105 1:CAS:528:DC%2BD28XislSmsLk%3D 10.2174/156800906776056518 16529540
    • (2006) Curr Cancer Drug Targets , vol.6 , pp. 89-105
    • Eble, J.A.1    Haier, J.2
  • 2
    • 0033551899 scopus 로고    scopus 로고
    • Integrin signaling
    • 1:CAS:528:DyaK1MXlt1Gns7o%3D 10.1126/science.285.5430.1028 10446041
    • FG Giancotti E Ruoslahti 1999 Integrin signaling Science 285 1028 1:CAS:528:DyaK1MXlt1Gns7o%3D 10.1126/science.285.5430.1028 10446041
    • (1999) Science , vol.285 , pp. 1028
    • Giancotti, F.G.1    Ruoslahti, E.2
  • 3
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • 1:CAS:528:DyaK38XitFWmtrg%3D 10.1016/0092-8674(92)90115-S 1555235
    • RO Hynes 1992 Integrins: versatility, modulation, and signaling in cell adhesion Cell 69 11 25 1:CAS:528:DyaK38XitFWmtrg%3D 10.1016/0092-8674(92)90115-S 1555235
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 5
    • 0033121275 scopus 로고    scopus 로고
    • The role of alphav integrins during angiogenesis: Insights into potential mechanisms of action and clinical development
    • 1:CAS:528:DyaK1MXivFansrs%3D 10.1172/JCI6869 10225964
    • BP Eliceiri DA Cheresh 1999 The role of alphav integrins during angiogenesis: insights into potential mechanisms of action and clinical development J Clin Invest 103 1227 1230 1:CAS:528:DyaK1MXivFansrs%3D 10.1172/JCI6869 10225964
    • (1999) J Clin Invest , vol.103 , pp. 1227-1230
    • Eliceiri, B.P.1    Cheresh, D.A.2
  • 6
    • 0037318003 scopus 로고    scopus 로고
    • Integrin alpha v beta 3 as a therapeutic target for blocking tumor-induced angiogenesis
    • 1:CAS:528:DC%2BD3sXovFShug%3D%3D 10.2174/1389450033346830 12558065
    • CC Kumar 2003 Integrin alpha v beta 3 as a therapeutic target for blocking tumor-induced angiogenesis Curr Drug Targets 4 123 131 1:CAS:528:DC%2BD3sXovFShug%3D%3D 10.2174/1389450033346830 12558065
    • (2003) Curr Drug Targets , vol.4 , pp. 123-131
    • Kumar, C.C.1
  • 7
    • 0028362876 scopus 로고
    • Requirement of vascular integrin alpha v beta 3 for angiogenesis
    • 1:CAS:528:DyaK2cXjt1Sis7w%3D 10.1126/science.7512751 7512751
    • PC Brooks RA Clark DA Cheresh 1994 Requirement of vascular integrin alpha v beta 3 for angiogenesis Science 264 569 571 1:CAS:528:DyaK2cXjt1Sis7w%3D 10.1126/science.7512751 7512751
    • (1994) Science , vol.264 , pp. 569-571
    • Brooks, P.C.1    Clark, R.A.2    Cheresh, D.A.3
  • 8
    • 58149329018 scopus 로고    scopus 로고
    • Integrin alphavbeta3-targeted radioimmunotherapy of glioblastoma multiforme
    • 1:CAS:528:DC%2BD1cXhtlylur%2FM 10.1158/1078-0432.CCR-08-0797 19010848
    • A Veeravagu Z Liu G Niu K Chen B Jia W Cai C Jin AR Hsu AJ Connolly V Tse, et al. 2008 Integrin alphavbeta3-targeted radioimmunotherapy of glioblastoma multiforme Clin Cancer Res 14 7330 7339 1:CAS:528: DC%2BD1cXhtlylur%2FM 10.1158/1078-0432.CCR-08-0797 19010848
    • (2008) Clin Cancer Res , vol.14 , pp. 7330-7339
    • Veeravagu, A.1    Liu, Z.2    Niu, G.3    Chen, K.4    Jia, B.5    Cai, W.6    Jin, C.7    Hsu, A.R.8    Connolly, A.J.9    Tse, V.10
  • 9
    • 45749108311 scopus 로고    scopus 로고
    • 99mTc-labeled bombesin(7-14)NH2 with favorable properties for SPECT imaging of colon cancer
    • 1:CAS:528:DC%2BD1cXmtFWhu70%3D 10.1021/bc700471z 18491928
    • J Shi B Jia Z Liu Z Yang Z Yu K Chen X Chen S Liu F Wang 2008 99mTc-labeled bombesin(7-14)NH2 with favorable properties for SPECT imaging of colon cancer Bioconjug Chem 19 1170 1178 1:CAS:528:DC%2BD1cXmtFWhu70%3D 10.1021/bc700471z 18491928
    • (2008) Bioconjug Chem , vol.19 , pp. 1170-1178
    • Shi, J.1    Jia, B.2    Liu, Z.3    Yang, Z.4    Yu, Z.5    Chen, K.6    Chen, X.7    Liu, S.8    Wang, F.9
  • 10
    • 57749090308 scopus 로고    scopus 로고
    • Integrin alpha v beta 3-targeted cancer therapy
    • 1:CAS:528:DC%2BD1MXhtl2hug%3D%3D 10.1002/ddr.20265 20628538
    • Z Liu F Wang X Chen 2008 Integrin alpha v beta 3-targeted cancer therapy Drug Development Research 69 329 339 1:CAS:528:DC%2BD1MXhtl2hug%3D%3D 10.1002/ddr.20265 20628538
    • (2008) Drug Development Research , vol.69 , pp. 329-339
    • Liu, Z.1    Wang, F.2    Chen, X.3
  • 11
    • 36749053493 scopus 로고    scopus 로고
    • [18F]galacto-RGD positron emission tomography for imaging of alphavbeta3 expression on the neovasculature in patients with squamous cell carcinoma of the head and neck
    • 1:CAS:528:DC%2BD2sXhtlSmu7nO 10.1158/1078-0432.CCR-07-0528 18006761
    • AJ Beer AL Grosu J Carlsen A Kolk M Sarbia I Stangier P Watzlowik HJ Wester R Haubner M Schwaiger 2007 [18F]galacto-RGD positron emission tomography for imaging of alphavbeta3 expression on the neovasculature in patients with squamous cell carcinoma of the head and neck Clin Cancer Res 13 6610 6616 1:CAS:528:DC%2BD2sXhtlSmu7nO 10.1158/1078-0432.CCR-07-0528 18006761
    • (2007) Clin Cancer Res , vol.13 , pp. 6610-6616
    • Beer, A.J.1    Grosu, A.L.2    Carlsen, J.3    Kolk, A.4    Sarbia, M.5    Stangier, I.6    Watzlowik, P.7    Wester, H.J.8    Haubner, R.9    Schwaiger, M.10
  • 13
    • 58249127731 scopus 로고    scopus 로고
    • Use of a novel Arg-Gly-Asp radioligand, 18F-AH111585, to determine changes in tumor vascularity after antitumor therapy
    • 1:CAS:528:DC%2BD1MXhvFCjt7s%3D 10.2967/jnumed.108.056077 19091899
    • MS Morrison SA Ricketts J Barnett A Cuthbertson J Tessier SR Wedge 2009 Use of a novel Arg-Gly-Asp radioligand, 18F-AH111585, to determine changes in tumor vascularity after antitumor therapy J Nucl Med 50 116 122 1:CAS:528:DC%2BD1MXhvFCjt7s%3D 10.2967/jnumed.108.056077 19091899
    • (2009) J Nucl Med , vol.50 , pp. 116-122
    • Morrison, M.S.1    Ricketts, S.A.2    Barnett, J.3    Cuthbertson, A.4    Tessier, J.5    Wedge, S.R.6
  • 14
    • 67349145987 scopus 로고    scopus 로고
    • (68)Ga-labeled cyclic RGD dimers with Gly(3) and PEG (4) linkers: Promising agents for tumor integrin alpha (v)beta (3) PET imaging
    • 1:CAS:528:DC%2BD1MXls1yjsL0%3D 10.1007/s00259-008-1045-1 19159928
    • Z Liu G Niu J Shi S Liu F Wang S Liu X Chen 2009 (68)Ga-labeled cyclic RGD dimers with Gly(3) and PEG (4) linkers: promising agents for tumor integrin alpha (v)beta (3) PET imaging Eur J Nucl Med Mol Imaging 36 947 957 1:CAS:528:DC%2BD1MXls1yjsL0%3D 10.1007/s00259-008-1045-1 19159928
    • (2009) Eur J Nucl Med Mol Imaging , vol.36 , pp. 947-957
    • Liu, Z.1    Niu, G.2    Shi, J.3    Liu, S.4    Wang, F.5    Liu, S.6    Chen, X.7
  • 15
    • 33645551144 scopus 로고    scopus 로고
    • Integrins: Molecular targets in cancer therapy
    • 1:CAS:528:DC%2BD28Xis1yiu70%3D 10.1007/s11912-006-0043-3 16507218
    • GC Tucker 2006 Integrins: molecular targets in cancer therapy Curr Oncol Rep 8 96 103 1:CAS:528:DC%2BD28Xis1yiu70%3D 10.1007/s11912-006-0043-3 16507218
    • (2006) Curr Oncol Rep , vol.8 , pp. 96-103
    • Tucker, G.C.1
  • 16
    • 0033870756 scopus 로고    scopus 로고
    • Targeted antiangiogenic therapy for cancer using Vitaxin: A humanized monoclonal antibody to the integrin alphavbeta3
    • 1:CAS:528:DC%2BD3cXmsVOmsbo%3D 10955784
    • JC Gutheil TN Campbell PR Pierce JD Watkins WD Huse DJ Bodkin DA Cheresh 2000 Targeted antiangiogenic therapy for cancer using Vitaxin: a humanized monoclonal antibody to the integrin alphavbeta3 Clin Cancer Res 6 3056 3061 1:CAS:528:DC%2BD3cXmsVOmsbo%3D 10955784
    • (2000) Clin Cancer Res , vol.6 , pp. 3056-3061
    • Gutheil, J.C.1    Campbell, T.N.2    Pierce, P.R.3    Watkins, J.D.4    Huse, W.D.5    Bodkin, D.J.6    Cheresh, D.A.7
  • 17
    • 0032568558 scopus 로고    scopus 로고
    • Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb
    • 1:CAS:528:DyaK1cXjtlKgsro%3D 10.1073/pnas.95.11.6037 9600913
    • H Wu G Beuerlein Y Nie H Smith BA Lee M Hensler WD Huse JD Watkins 1998 Stepwise in vitro affinity maturation of Vitaxin, an alphav beta3-specific humanized mAb Proc Natl Acad Sci USA 95 6037 1:CAS:528:DyaK1cXjtlKgsro%3D 10.1073/pnas.95.11.6037 9600913
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6037
    • Wu, H.1    Beuerlein, G.2    Nie, Y.3    Smith, H.4    Lee, B.A.5    Hensler, M.6    Huse, W.D.7    Watkins, J.D.8
  • 18
    • 33748616254 scopus 로고    scopus 로고
    • Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism
    • 1:CAS:528:DC%2BD28Xos1Gqt7w%3D 10.2174/187152006778226530 17017851
    • W Cai X Chen 2006 Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism Anticancer Agents Med Chem 6 407 428 1:CAS:528: DC%2BD28Xos1Gqt7w%3D 10.2174/187152006778226530 17017851
    • (2006) Anticancer Agents Med Chem , vol.6 , pp. 407-428
    • Cai, W.1    Chen, X.2
  • 19
    • 38149098569 scopus 로고    scopus 로고
    • Phase i and pharmacokinetic study of etaracizumab (Abegrin), a humanized monoclonal antibody against alphavbeta3 integrin receptor, in patients with advanced solid tumors
    • 1:CAS:528:DC%2BD1cXlt1aqtg%3D%3D 10.1007/s10637-007-9077-0 17876527
    • C Delbaldo E Raymond K Vera L Hammershaimb K Kaucic S Lozahic M Marty S Faivre 2008 Phase I and pharmacokinetic study of etaracizumab (Abegrin), a humanized monoclonal antibody against alphavbeta3 integrin receptor, in patients with advanced solid tumors Invest New Drugs 26 35 43 1:CAS:528: DC%2BD1cXlt1aqtg%3D%3D 10.1007/s10637-007-9077-0 17876527
    • (2008) Invest New Drugs , vol.26 , pp. 35-43
    • Delbaldo, C.1    Raymond, E.2    Vera, K.3    Hammershaimb, L.4    Kaucic, K.5    Lozahic, S.6    Marty, M.7    Faivre, S.8
  • 20
    • 0035706407 scopus 로고    scopus 로고
    • A pilot trial of Vitaxin, a humanized anti-vitronectin receptor (anti alpha v beta 3) antibody in patients with metastatic cancer
    • 1:CAS:528:DC%2BD3MXktF2hu7k%3D 10.1089/108497801300189218 11385959
    • JA Posey MB Khazaeli A DelGrosso MN Saleh CY Lin W Huse AF LoBuglio 2001 A pilot trial of Vitaxin, a humanized anti-vitronectin receptor (anti alpha v beta 3) antibody in patients with metastatic cancer Cancer Biother Radiopharm 16 125 132 1:CAS:528:DC%2BD3MXktF2hu7k%3D 10.1089/108497801300189218 11385959
    • (2001) Cancer Biother Radiopharm , vol.16 , pp. 125-132
    • Posey, J.A.1    Khazaeli, M.B.2    Delgrosso, A.3    Saleh, M.N.4    Lin, C.Y.5    Huse, W.6    Lobuglio, A.F.7
  • 21
    • 33750377517 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of 64Cu-labeled Abegrin, a humanized monoclonal antibody against integrin alpha v beta 3
    • 1:CAS:528:DC%2BD28XhtVams73J 10.1158/0008-5472.CAN-06-1480 17018625
    • W Cai Y Wu K Chen Q Cao DA Tice X Chen 2006 In vitro and in vivo characterization of 64Cu-labeled Abegrin, a humanized monoclonal antibody against integrin alpha v beta 3 Cancer Res 66 9673 9681 1:CAS:528: DC%2BD28XhtVams73J 10.1158/0008-5472.CAN-06-1480 17018625
    • (2006) Cancer Res , vol.66 , pp. 9673-9681
    • Cai, W.1    Wu, Y.2    Chen, K.3    Cao, Q.4    Tice, D.A.5    Chen, X.6
  • 22
    • 49549090861 scopus 로고    scopus 로고
    • Imaging liver metastases of colorectal cancer patients with radiolabelled bevacizumab: Lack of correlation with VEGF-A expression
    • 1:CAS:528:DC%2BD1cXhtVamt7rL 10.1016/j.ejca.2008.05.026 18632262
    • MG Scheer TH Stollman OC Boerman K Verrijp FC Sweep WP Leenders TJ Ruers WJ Oyen 2008 Imaging liver metastases of colorectal cancer patients with radiolabelled bevacizumab: Lack of correlation with VEGF-A expression Eur J Cancer 44 1835 1840 1:CAS:528:DC%2BD1cXhtVamt7rL 10.1016/j.ejca.2008.05.026 18632262
    • (2008) Eur J Cancer , vol.44 , pp. 1835-1840
    • Scheer, M.G.1    Stollman, T.H.2    Boerman, O.C.3    Verrijp, K.4    Sweep, F.C.5    Leenders, W.P.6    Ruers, T.J.7    Oyen, W.J.8
  • 23
    • 57349156203 scopus 로고    scopus 로고
    • 90Y-ibritumomab therapy in refractory non-Hodgkin's lymphoma: Observations from 111In-ibritumomab pretreatment imaging
    • 10.2967/jnumed.108.052928 18927323
    • A Iagaru SS Gambhir ML Goris 2008 90Y-ibritumomab therapy in refractory non-Hodgkin's lymphoma: observations from 111In-ibritumomab pretreatment imaging J Nucl Med 49 1809 1812 10.2967/jnumed.108.052928 18927323
    • (2008) J Nucl Med , vol.49 , pp. 1809-1812
    • Iagaru, A.1    Gambhir, S.S.2    Goris, M.L.3
  • 24
    • 46749104779 scopus 로고    scopus 로고
    • Antibody mass escalation study in patients with castration-resistant prostate cancer using 111In-J591: Lesion detectability and dosimetric projections for 90Y radioimmunotherapy
    • 10.2967/jnumed.107.049502 18552139
    • N Pandit-Taskar JA O'Donoghue MJ Morris EA Wills LH Schwartz M Gonen HI Scher SM Larson CR Divgi 2008 Antibody mass escalation study in patients with castration-resistant prostate cancer using 111In-J591: lesion detectability and dosimetric projections for 90Y radioimmunotherapy J Nucl Med 49 1066 1074 10.2967/jnumed.107.049502 18552139
    • (2008) J Nucl Med , vol.49 , pp. 1066-1074
    • Pandit-Taskar, N.1    O'Donoghue, J.A.2    Morris, M.J.3    Wills, E.A.4    Schwartz, L.H.5    Gonen, M.6    Scher, H.I.7    Larson, S.M.8    Divgi, C.R.9
  • 25
    • 0035960126 scopus 로고    scopus 로고
    • Trastuzumab and breast cancer
    • 1:CAS:528:DC%2BD3MXntlehtbk%3D 10.1056/NEJM200109273451312 11575295
    • TM Behr M Behe B Wormann 2001 Trastuzumab and breast cancer N Engl J Med 345 995 996 1:CAS:528:DC%2BD3MXntlehtbk%3D 10.1056/NEJM200109273451312 11575295
    • (2001) N Engl J Med , vol.345 , pp. 995-996
    • Behr, T.M.1    Behe, M.2    Wormann, B.3
  • 26
    • 57149089463 scopus 로고    scopus 로고
    • Glutathione Peroxidase 2 Inhibits Cyclooxygenase-2-Mediated Migration and Invasion of HT-29 Adenocarcinoma Cells but Supports Their Growth as Tumors in Nude Mice
    • 1:CAS:528:DC%2BD1cXhsVegtbvF 10.1158/0008-5472.CAN-08-1321 19047153
    • A Banning A Kipp S Schmitmeier M Lowinger S Florian S Krehl S Thalmann R Thierbach P Steinberg R Brigelius-Flohe 2008 Glutathione Peroxidase 2 Inhibits Cyclooxygenase-2-Mediated Migration and Invasion of HT-29 Adenocarcinoma Cells but Supports Their Growth as Tumors in Nude Mice Cancer Res 68 9746 9753 1:CAS:528:DC%2BD1cXhsVegtbvF 10.1158/0008-5472.CAN-08-1321 19047153
    • (2008) Cancer Res , vol.68 , pp. 9746-9753
    • Banning, A.1    Kipp, A.2    Schmitmeier, S.3    Lowinger, M.4    Florian, S.5    Krehl, S.6    Thalmann, S.7    Thierbach, R.8    Steinberg, P.9    Brigelius-Flohe, R.10
  • 27
    • 60849131263 scopus 로고    scopus 로고
    • In-vitro internalization and in-vivo tumor uptake of anti-EGFR monoclonal antibody LA22 in A549 lung cancer cells and animal model
    • 10.1089/cbr.2008.0537 19216631
    • Z Liu Z Yu W He S Ma L Sun F Wang 2009 In-vitro internalization and in-vivo tumor uptake of anti-EGFR monoclonal antibody LA22 in A549 lung cancer cells and animal model Cancer Biother Radiopharm 24 15 24 10.1089/cbr.2008.0537 19216631
    • (2009) Cancer Biother Radiopharm , vol.24 , pp. 15-24
    • Liu, Z.1    Yu, Z.2    He, W.3    Ma, S.4    Sun, L.5    Wang, F.6
  • 28
    • 33748434207 scopus 로고    scopus 로고
    • Inhibition of human tumor xenograft growth in nude mice by a conjugate of monoclonal antibody LA22 to epidermal growth factor receptor with anti-tumor antibiotics mitomycin C
    • 1:CAS:528:DC%2BD28Xps1Ogt70%3D 10.1016/j.bbrc.2006.08.114 16950201
    • W Shao S Zhao Z Liu J Zhang S Ma JD Sato P Zhang M Tong J Han Y Wang, et al. 2006 Inhibition of human tumor xenograft growth in nude mice by a conjugate of monoclonal antibody LA22 to epidermal growth factor receptor with anti-tumor antibiotics mitomycin C Biochem Biophys Res Commun 349 816 824 1:CAS:528:DC%2BD28Xps1Ogt70%3D 10.1016/j.bbrc.2006.08.114 16950201
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 816-824
    • Shao, W.1    Zhao, S.2    Liu, Z.3    Zhang, J.4    Ma, S.5    Sato, J.D.6    Zhang, P.7    Tong, M.8    Han, J.9    Wang, Y.10
  • 29
    • 60549098667 scopus 로고    scopus 로고
    • Dual Integrin and Gastrin-Releasing Peptide Receptor Targeted Tumor Imaging Using (18)F-labeled PEGylated RGD-Bombesin Heterodimer (18)F-FB-PEG(3)-Glu-RGD-BBN
    • 1:CAS:528:DC%2BD1MXnt1Kg 10.1021/jm801285t 19113865
    • Z Liu Y Yan FT Chin F Wang X Chen 2009 Dual Integrin and Gastrin-Releasing Peptide Receptor Targeted Tumor Imaging Using (18)F-labeled PEGylated RGD-Bombesin Heterodimer (18)F-FB-PEG(3)-Glu-RGD-BBN J Med Chem 52 425 432 1:CAS:528:DC%2BD1MXnt1Kg 10.1021/jm801285t 19113865
    • (2009) J Med Chem , vol.52 , pp. 425-432
    • Liu, Z.1    Yan, Y.2    Chin, F.T.3    Wang, F.4    Chen, X.5
  • 30
    • 52249121442 scopus 로고    scopus 로고
    • In vivo gamma imaging of the secondary tumors of transplanted human fetal striatum neural stem cells-derived primary tumor cells
    • 10.1097/WNR.0b013e328303c020 18580570
    • Q He Z Liu B Jia X Li J Shi J Zhang F Lan Z Yang Y Liu L Shen, et al. 2008 In vivo gamma imaging of the secondary tumors of transplanted human fetal striatum neural stem cells-derived primary tumor cells NeuroReport 19 1009 1014 10.1097/WNR.0b013e328303c020 18580570
    • (2008) NeuroReport , vol.19 , pp. 1009-1014
    • He, Q.1    Liu, Z.2    Jia, B.3    Li, X.4    Shi, J.5    Zhang, J.6    Lan, F.7    Yang, Z.8    Liu, Y.9    Shen, L.10
  • 31
    • 0037334516 scopus 로고    scopus 로고
    • Vascular permeability enhancement in solid tumor: Various factors, mechanisms involved and its implications
    • 1:CAS:528:DC%2BD3sXhvFGktLc%3D 10.1016/S1567-5769(02)00271-0 12639809
    • H Maeda J Fang T Inutsuka Y Kitamoto 2003 Vascular permeability enhancement in solid tumor: various factors, mechanisms involved and its implications Int Immunopharmacol 3 319 328 1:CAS:528:DC%2BD3sXhvFGktLc%3D 10.1016/S1567-5769(02)00271-0 12639809
    • (2003) Int Immunopharmacol , vol.3 , pp. 319-328
    • Maeda, H.1    Fang, J.2    Inutsuka, T.3    Kitamoto, Y.4
  • 32
    • 1542328068 scopus 로고    scopus 로고
    • Comparative in vivo stability of copper-64-labeled cross-bridged and conventional tetraazamacrocyclic complexes
    • 1:CAS:528:DC%2BD2cXhtFagtLw%3D 10.1021/jm030383m 14998334
    • CA Boswell X Sun W Niu GR Weisman EH Wong AL Rheingold CJ Anderson 2004 Comparative in vivo stability of copper-64-labeled cross-bridged and conventional tetraazamacrocyclic complexes J Med Chem 47 1465 1474 1:CAS:528:DC%2BD2cXhtFagtLw%3D 10.1021/jm030383m 14998334
    • (2004) J Med Chem , vol.47 , pp. 1465-1474
    • Boswell, C.A.1    Sun, X.2    Niu, W.3    Weisman, G.R.4    Wong, E.H.5    Rheingold, A.L.6    Anderson, C.J.7
  • 33
    • 67650093751 scopus 로고    scopus 로고
    • Small-animal PET of tumors with 64Cu-labeled RGD-bombesin heterodimer
    • 1:CAS:528:DC%2BD1MXpsV2gsbY%3D 10.2967/jnumed.108.061739 19525469
    • Z Liu Z Li Q Cao S Liu F Wang X Chen 2009 Small-animal PET of tumors with 64Cu-labeled RGD-bombesin heterodimer J Nucl Med 50 1168 1177 1:CAS:528:DC%2BD1MXpsV2gsbY%3D 10.2967/jnumed.108.061739 19525469
    • (2009) J Nucl Med , vol.50 , pp. 1168-1177
    • Liu, Z.1    Li, Z.2    Cao, Q.3    Liu, S.4    Wang, F.5    Chen, X.6
  • 34
    • 11144228601 scopus 로고    scopus 로고
    • Preparation and biological evaluation of copper-64-labeled tyr3-octreotate using a cross-bridged macrocyclic chelator
    • 1:CAS:528:DC%2BD2cXhtFGjsL7F 10.1158/1078-0432.CCR-04-1084 15623652
    • JE Sprague Y Peng X Sun GR Weisman EH Wong S Achilefu CJ Anderson 2004 Preparation and biological evaluation of copper-64-labeled tyr3-octreotate using a cross-bridged macrocyclic chelator Clin Cancer Res 10 8674 8682 1:CAS:528:DC%2BD2cXhtFGjsL7F 10.1158/1078-0432.CCR-04-1084 15623652
    • (2004) Clin Cancer Res , vol.10 , pp. 8674-8682
    • Sprague, J.E.1    Peng, Y.2    Sun, X.3    Weisman, G.R.4    Wong, E.H.5    Achilefu, S.6    Anderson, C.J.7
  • 35
    • 34547630542 scopus 로고    scopus 로고
    • [64Cu-NOTA-8-Aoc-BBN(7-14)NH2] targeting vector for positron-emission tomography imaging of gastrin-releasing peptide receptor-expressing tissues
    • 1:CAS:528:DC%2BD2sXos1ehtLw%3D 10.1073/pnas.0705347104 17626788
    • AF Prasanphanich PK Nanda TL Rold L Ma MR Lewis JC Garrison TJ Hoffman GL Sieckman SD Figueroa CJ Smith 2007 [64Cu-NOTA-8-Aoc-BBN(7-14)NH2] targeting vector for positron-emission tomography imaging of gastrin-releasing peptide receptor-expressing tissues Proc Natl Acad Sci U S A 104 12462 12467 1:CAS:528:DC%2BD2sXos1ehtLw%3D 10.1073/pnas.0705347104 17626788
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 12462-12467
    • Prasanphanich, A.F.1    Nanda, P.K.2    Rold, T.L.3    Ma, L.4    Lewis, M.R.5    Garrison, J.C.6    Hoffman, T.J.7    Sieckman, G.L.8    Figueroa, S.D.9    Smith, C.J.10
  • 36
    • 0029846478 scopus 로고    scopus 로고
    • Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors
    • 1:CAS:528:DyaK28XnsVakur8%3D 10.1097/00005072-199611000-00005 8939197
    • CL Gladson 1996 Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors J Neuropathol Exp Neurol 55 1143 1149 1:CAS:528:DyaK28XnsVakur8%3D 10.1097/00005072-199611000-00005 8939197
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 1143-1149
    • Gladson, C.L.1
  • 37
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
    • 1:CAS:528:DC%2BD3MXmtlekt7k%3D 10.1016/S0065-2571(00)00013-3 11384745
    • H Maeda 2001 The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting Adv Enzyme Regul 41 189 207 1:CAS:528:DC%2BD3MXmtlekt7k%3D 10.1016/S0065- 2571(00)00013-3 11384745
    • (2001) Adv Enzyme Regul , vol.41 , pp. 189-207
    • Maeda, H.1
  • 38
    • 58249105735 scopus 로고    scopus 로고
    • Disparity between in vivo EGFR expression and 89Zr-labeled cetuximab uptake assessed with PET
    • 1:CAS:528:DC%2BD1MXhvFCjt7g%3D 10.2967/jnumed.108.054312 19091906
    • HJ Aerts L Dubois L Perk P Vermaelen GA van Dongen BG Wouters P Lambin 2009 Disparity between in vivo EGFR expression and 89Zr-labeled cetuximab uptake assessed with PET J Nucl Med 50 123 131 1:CAS:528:DC%2BD1MXhvFCjt7g%3D 10.2967/jnumed.108.054312 19091906
    • (2009) J Nucl Med , vol.50 , pp. 123-131
    • Aerts, H.J.1    Dubois, L.2    Perk, L.3    Vermaelen, P.4    Van Dongen, G.A.5    Wouters, B.G.6    Lambin, P.7
  • 39
    • 57249094344 scopus 로고    scopus 로고
    • Associations between the uptake of 111In-DTPA-trastuzumab, HER2 density and response to trastuzumab (Herceptin) in athymic mice bearing subcutaneous human tumour xenografts
    • 1:CAS:528:DC%2BD1cXhsVGqurzK 10.1007/s00259-008-0923-x 18712381
    • K McLarty B Cornelissen DA Scollard SJ Done K Chun RM Reilly 2009 Associations between the uptake of 111In-DTPA-trastuzumab, HER2 density and response to trastuzumab (Herceptin) in athymic mice bearing subcutaneous human tumour xenografts Eur J Nucl Med Mol Imaging 36 81 93 1:CAS:528: DC%2BD1cXhsVGqurzK 10.1007/s00259-008-0923-x 18712381
    • (2009) Eur J Nucl Med Mol Imaging , vol.36 , pp. 81-93
    • McLarty, K.1    Cornelissen, B.2    Scollard, D.A.3    Done, S.J.4    Chun, K.5    Reilly, R.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.