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Volumn 83, Issue 2, 2008, Pages 349-353

The role of molecular imaging in drug discovery and development

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; IBRITUMOMAB TIUXETAN; TOSITUMOMAB I 131; TRACER;

EID: 38349095953     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/sj.clpt.6100467     Document Type: Review
Times cited : (124)

References (25)
  • 1
    • 0142089831 scopus 로고    scopus 로고
    • A path to improved pharmaceutical productivity
    • Cohen, C.M. A path to improved pharmaceutical productivity. Nat. Rev. Drug Discov. 2, 751-753 (2003).
    • (2003) Nat. Rev. Drug Discov , vol.2 , pp. 751-753
    • Cohen, C.M.1
  • 2
    • 0038004636 scopus 로고    scopus 로고
    • Clinical biomarkers in drug discovery and development
    • Frank, R. & Hargreaves, R. Clinical biomarkers in drug discovery and development. Nat. Rev. Drug Discov. 2, 566-580 (2003).
    • (2003) Nat. Rev. Drug Discov , vol.2 , pp. 566-580
    • Frank, R.1    Hargreaves, R.2
  • 3
    • 0037313516 scopus 로고    scopus 로고
    • Molecular imaging in drug discovery and development
    • Rudin, M. & Weissleder, R. Molecular imaging in drug discovery and development. Nat. Rev. Drug Discov. 2, 123-131 (2003).
    • (2003) Nat. Rev. Drug Discov , vol.2 , pp. 123-131
    • Rudin, M.1    Weissleder, R.2
  • 4
    • 34247562186 scopus 로고    scopus 로고
    • Integrating non-invasive molecular imaging into molecular medicine - an evolving paradigm
    • Massoud, T.F. & Gambhir, S.S. Integrating non-invasive molecular imaging into molecular medicine - an evolving paradigm. Trends Mol. Med. 13, 183-191 (2007).
    • (2007) Trends Mol. Med , vol.13 , pp. 183-191
    • Massoud, T.F.1    Gambhir, S.S.2
  • 6
    • 12344300543 scopus 로고    scopus 로고
    • Spying on cancer - molecular imaging in vivo with genetically encoded reporters
    • Gross, S. & Piwnica-Worms, D. Spying on cancer - molecular imaging in vivo with genetically encoded reporters. Cancer Cell 7, 5-15 (2005).
    • (2005) Cancer Cell , vol.7 , pp. 5-15
    • Gross, S.1    Piwnica-Worms, D.2
  • 7
    • 34547606190 scopus 로고    scopus 로고
    • The opportunities and challenges of developing imaging biomarkers to study lung function and disease
    • Schuster, D.P. The opportunities and challenges of developing imaging biomarkers to study lung function and disease. Am. J. Respir. Crit. Care Med. 176, 224-230 (2007).
    • (2007) Am. J. Respir. Crit. Care Med , vol.176 , pp. 224-230
    • Schuster, D.P.1
  • 8
    • 33847720312 scopus 로고    scopus 로고
    • In vivo imaging of siRNA delivery and silencing in tumors
    • Medarova, Z., Pham, W., Farrar, C., Petkova, V. & Moore, A. In vivo imaging of siRNA delivery and silencing in tumors. Nat. Med. 13, 372-377 (2007).
    • (2007) Nat. Med , vol.13 , pp. 372-377
    • Medarova, Z.1    Pham, W.2    Farrar, C.3    Petkova, V.4    Moore, A.5
  • 11
    • 24944566857 scopus 로고    scopus 로고
    • Small animal imaging in drug development
    • Pomper, M.G. & Lee, J.S. Small animal imaging in drug development. Current Pharmaceutical Design 11, 3247-3272 (2005).
    • (2005) Current Pharmaceutical Design , vol.11 , pp. 3247-3272
    • Pomper, M.G.1    Lee, J.S.2
  • 12
    • 34047218964 scopus 로고    scopus 로고
    • Multimodality imaging of tumor xenografts and metastases in mice with combined small-animal PET, small-animal CT and bioluminesence imaging
    • Deroose, C.M. et al. Multimodality imaging of tumor xenografts and metastases in mice with combined small-animal PET, small-animal CT and bioluminesence imaging. J. Nuc. Med. 48, 295-303 (2007).
    • (2007) J. Nuc. Med , vol.48 , pp. 295-303
    • Deroose, C.M.1
  • 13
    • 34447559466 scopus 로고    scopus 로고
    • Role of in vivo imaging of the central nervous system for developing novel drugs
    • Rueger, M.A. et al. Role of in vivo imaging of the central nervous system for developing novel drugs. Q. J. Nucl. Med. Mol. Imaging 51, 164-181 (2007).
    • (2007) Q. J. Nucl. Med. Mol. Imaging , vol.51 , pp. 164-181
    • Rueger, M.A.1
  • 14
    • 34548695230 scopus 로고    scopus 로고
    • Molecular neuroimaging: From conventional to emerging techniques
    • Hammoud, D.A., Hoffman J.M. & Pomper, M. Molecular neuroimaging: from conventional to emerging techniques. Radiology 245, 21-42 (2007).
    • (2007) Radiology , vol.245 , pp. 21-42
    • Hammoud, D.A.1    Hoffman, J.M.2    Pomper, M.3
  • 15
    • 34547411013 scopus 로고    scopus 로고
    • 18F]MK-9470, a positron emission tomography (PET)tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor
    • Burns, H.D. et al. [18F]MK-9470, a positron emission tomography (PET)tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor. Proc. Natl. Acad. Sci. USA 104, 9800-9805 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 9800-9805
    • Burns, H.D.1
  • 17
    • 33748920715 scopus 로고    scopus 로고
    • Neuropeptide Y5 receptor antagonism does not induce clinically meaningful weight loss in overweight and obese adults
    • Erondu, N. et al. Neuropeptide Y5 receptor antagonism does not induce clinically meaningful weight loss in overweight and obese adults. Cell Metab. 4, 275-282 (2006).
    • (2006) Cell Metab , vol.4 , pp. 275-282
    • Erondu, N.1
  • 18
    • 2342483811 scopus 로고    scopus 로고
    • Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant
    • Bergström, M. et al. Human positron emission tomography studies of brain neurokinin 1 receptor occupancy by aprepitant. Biol. Psychiatry 55, 1007-1012 (2004).
    • (2004) Biol. Psychiatry , vol.55 , pp. 1007-1012
    • Bergström, M.1
  • 19
    • 32144442187 scopus 로고    scopus 로고
    • Lack of efficacy of the substance P (neurokinin 1 receptor) antagonist aprepitant in the treatment of major depressive disorder
    • Keller, M. et al. Lack of efficacy of the substance P (neurokinin 1 receptor) antagonist aprepitant in the treatment of major depressive disorder. Biol. Psychiatry 59, 216-223 (2006).
    • (2006) Biol. Psychiatry , vol.59 , pp. 216-223
    • Keller, M.1
  • 20
    • 34548587491 scopus 로고    scopus 로고
    • Overview of early response assessment in lymphoma with FDG-PET
    • MacManus, M.P. et al. Overview of early response assessment in lymphoma with FDG-PET. Cancer Imaging 7, 10-18 (2007).
    • (2007) Cancer Imaging , vol.7 , pp. 10-18
    • MacManus, M.P.1
  • 21
    • 38349118845 scopus 로고    scopus 로고
    • fNIH lung and lymphoma [18F] FDG consortia. 〈http://www. biomarkersconsortium.org/index.php?option=com_content&task=view&id= 93&Itemid=143〉 (2007).
    • fNIH lung and lymphoma [18F] FDG consortia. 〈http://www. biomarkersconsortium.org/index.php?option=com_content&task=view&id= 93&Itemid=143〉 (2007).
  • 22
    • 34249747744 scopus 로고    scopus 로고
    • Imaging as a biomarker for decision making in drug development
    • ed. Beckmann, N, Ch. 3, Taylor & Francis, New York
    • Hargreaves, R. & Wagner, J. Imaging as a biomarker for decision making in drug development. In In Vivo MR Techniques in Drug Discovery and Development (ed. Beckmann, N.) Ch. 3, 31-46 (Taylor & Francis, New York, 2006).
    • (2006) In Vivo MR Techniques in Drug Discovery and Development , pp. 31-46
    • Hargreaves, R.1    Wagner, J.2
  • 23
    • 34548230533 scopus 로고    scopus 로고
    • Molecular Imaging of cardiovascular disease
    • Jaffer, F.A., Libby, P. & Weissleder, R. Molecular Imaging of cardiovascular disease. Circulation 116, 1052-1061 (2007).
    • (2007) Circulation , vol.116 , pp. 1052-1061
    • Jaffer, F.A.1    Libby, P.2    Weissleder, R.3
  • 25
    • 0034614637 scopus 로고    scopus 로고
    • Hallmarks of cancer
    • Hanahan, D. & Weinberg, R.A. Hallmarks of cancer. Cell 100, 57-70 (2000).
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.