18F-labeled galacto and PEGylated RGD dimers for PET imaging of αvβ3 integrin expression

Molecular Imaging and Biology

Volumn 12, Issue 5, 2010, Pages 530-538

  Liu, Shuanglong ^a   Liu, Zhaofei ^a   Chen, Kai ^a   Yan, Yongjun ^a   Watzlowik, Petra ^b   Wester, Hans Jürgen ^b   Chin, Frederick T ^a   Chen, Xiaoyuan ^a  

^a STANFORD UNIVERSITY   (United States)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Integrin v 3; Polyvalency; RGD dimer; Small animal PET

Indexed keywords

2 FLUOROPROPIONATE PEGYLATED ARGINYLGLYCYLASPARTIC ACID F 18; 2 FLUOROPROPIONATE SUGAR AMINO ACID ARGINYLGLYCYLASPARTIC ACID F 18; 4 NITROPHENYL 2 FLUOROPROPIONATE F 18; DIMER; FLUORINE GALACTO ARGINYLGLYCYLASPARTIC ACID F 18; MONOMER; N SUCCINIMIDYL 4 FLUOROBENZOATE F 18; RADIOPHARMACEUTICAL AGENT; TRACER; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR; ARGINYL-GLYCYL-ASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID; FLUORINE; GALACTOSE; MACROGOL DERIVATIVE; OLIGOPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CELL KINETICS; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DISEASE MODEL; DRUG DISTRIBUTION; DRUG LABELING; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG UPTAKE; GLIOBLASTOMA; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR IMAGING; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR XENOGRAFT; ANIMAL; CHEMISTRY; DIMERIZATION; METABOLISM; TISSUE DISTRIBUTION; TUMOR CELL LINE; XENOGRAFT;

ANIMALIA;

ANIMALS; CELL LINE, TUMOR; DIMERIZATION; FLUORINE RADIOISOTOPES; GALACTOSE; HUMANS; INTEGRIN ALPHAVBETA3; OLIGOPEPTIDES; POLYETHYLENE GLYCOLS; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 77956264376     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-009-0284-2     Document Type: Article

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