Bioluminescent imaging of Cdk2 inhibition in vivo

Nature Medicine

Volumn 10, Issue 6, 2004, Pages 643-648

  Zhang, Guo Jun ^a,f   Safran, Michal ^a   Wei, Wenyi ^a   Sorensen, Erik ^b   Lassota, Peter ^b   Zhelev, Nikolai ^c,d   Neuberg, Donna S ^e   Shapiro, Geoffrey ^a   Kaelin Jr , William G ^a,f  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^c CYCLACEL LTD   (United Kingdom)

^d UNIVERSITY OF ABERTAY DUNDEE   (United Kingdom)

^e DANA FARBER CANCER INSTITUTE   (United States)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR; F BOX PROTEIN; FLAVOPIRIDOL; LUCIFERASE; PROTEIN P27; ROSCOVITINE; S PHASE KINASE ASSOCIATED PROTEIN 2; SMALL INTERFERING RNA; THREONINE; UBIQUITIN PROTEIN LIGASE;

ARTICLE; BINDING SITE; BIOLUMINESCENCE; CELL CYCLE; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMAGING; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; UBIQUITINATION;

ANIMALS; CDC2-CDC28 KINASES; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CELL TRANSPLANTATION; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DIAGNOSTIC IMAGING; ENZYME INHIBITORS; GENES, REPORTER; HUMANS; LUCIFERASES; LUMINESCENT MEASUREMENTS; MICE; MICE, NUDE; RECOMBINANT FUSION PROTEINS; S-PHASE KINASE-ASSOCIATED PROTEINS; TUMOR SUPPRESSOR PROTEINS;

STAPHYLOCOCCUS PHAGE 187;

EID: 2942755714     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1047     Document Type: Article

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