68Ga-labeled cyclic RGD dimers with Gly3 and PEG 4 linkers: Promising agents for tumor integrin α vβ3 PET imaging

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 36, Issue 6, 2009, Pages 947-957

  Liu, Zhaofei ^a,b   Niu, Gang ^a   Shi, Jiyun ^b,c   Liu, Shuanglong ^a   Wang, Fan ^b   Liu, Shuang ^c   Chen, Xiaoyuan ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PEKING UNIVERSITY   (China)

^c PURDUE UNIVERSITY   (United States)

Author keywords

68Ga; Angiogenesis molecular imaging targeting; Bivalency; Integrin v 3; PET tracer; Small animal PET

Indexed keywords

1,4,7 TRIAZACYCLONONANETRIACETIC ACID; 1,4,7 TRIAZACYCLONONANETRIACETIC ACID 15 AMINO 4,7,10,13 TETRAOXAPENTADECANOIC ACID GA 68; 1,4,7 TRIAZACYCLONONANETRIACETIC ACID ARGINYLGLYCYLASPARTIC ACID GA 68; 1,4,7 TRIAZACYCLONONANETRIACETIC ACID GLYCYLGLYCYLGLYCYLARGINYLGLYCYLASPARTIC ACID GA 68; ACETIC ACID DERIVATIVE; ARGINYLGLYCYLASPARTIC ACID; GALLIUM 68; GLYCINE DERIVATIVE; TRACER; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; COST CONTROL; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG STRUCTURE; EARLY DIAGNOSIS; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VIVO STUDY; ISOTOPE LABELING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR IMAGING; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; RADIOCHEMISTRY; XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; DIMERIZATION; FEMALE; GALLIUM RADIOISOTOPES; GLYCINE; HUMANS; INTEGRIN ALPHAVBETA3; MICE; NEOPLASMS; PEPTIDES, CYCLIC; POLYETHYLENE GLYCOLS; POSITRON-EMISSION TOMOGRAPHY; RADIOCHEMISTRY; STAINING AND LABELING; TISSUE DISTRIBUTION;

EID: 67349145987     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-008-1045-1     Document Type: Article

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