Enhanced dentate gyrus synaptic plasticity but reduced neurogenesis in a mouse model of amyloidosis

Neurobiology of Disease

Volumn 40, Issue 2, 2010, Pages 386-393

  Poirier, Raphaël ^a   Veltman, Inge ^a   Pflimlin, Marie Claire ^a   Knoflach, Frédéric ^a   Metzger, Friedrich ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Alzheimer; APP; BDNF; Dentate gyrus; IGF; LTP; Neurogenesis; Potentiation; Presenilin; PS2

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PICROTOXIN; PRESENILIN 2; SOMATOMEDIN C; VASCULOTROPIN;

ALZHEIMER DISEASE; AMYLOIDOSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE GYRUS; DISEASE ASSOCIATION; DISEASE MODEL; LONG TERM POTENTIATION; MALE; MOUSE; NERVE CELL PLASTICITY; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; SENILE PLAQUE; TRANSGENIC MOUSE;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOIDOSIS; ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; CELL SURVIVAL; DENTATE GYRUS; DISEASE MODELS, ANIMAL; LONG-TERM POTENTIATION; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURAL STEM CELLS; NEUROGENESIS; NEURONAL PLASTICITY; PLAQUE, AMYLOID; PRESENILIN-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SYNAPSES;

EID: 80052582895     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2010.06.014     Document Type: Article

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