메뉴 건너뛰기




Volumn 118, Issue 8, 2008, Pages 2747-2757

Multidrug resistance-associated protein 4 regulates cAMP-dependent signaling pathways and controls human and rat SMC proliferation

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYCLIC GMP; MULTIDRUG RESISTANCE PROTEIN 4;

EID: 48749083091     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI35067     Document Type: Article
Times cited : (103)

References (57)
  • 1
    • 33751241720 scopus 로고    scopus 로고
    • Epac proteins: Multi-purpose cAMP targets
    • Bos, J.L. 2006. Epac proteins: multi-purpose cAMP targets. Trends Biochem. Sci. 31:680-686.
    • (2006) Trends Biochem. Sci , vol.31 , pp. 680-686
    • Bos, J.L.1
  • 2
    • 0036301043 scopus 로고    scopus 로고
    • Cyclic nucleotide-gated ion channels
    • Kaupp, U.B., and Seifert, R. 2002. Cyclic nucleotide-gated ion channels. Physiol. Rev. 82:769-824.
    • (2002) Physiol. Rev , vol.82 , pp. 769-824
    • Kaupp, U.B.1    Seifert, R.2
  • 3
    • 0042859823 scopus 로고    scopus 로고
    • Cyclic GMP phosphodiesterases and regulation of smooth muscle function
    • Rybalkin, S.D., Yan, C., Bornfeldt, K.E., and Beavo, J.A. 2003. Cyclic GMP phosphodiesterases and regulation of smooth muscle function. Circ. Res. 93:280-291.
    • (2003) Circ. Res , vol.93 , pp. 280-291
    • Rybalkin, S.D.1    Yan, C.2    Bornfeldt, K.E.3    Beavo, J.A.4
  • 4
    • 33749665081 scopus 로고    scopus 로고
    • Compartmentation of cyclic nucleotide signaling in the heart: The role of cyclic nucleotide phosphodiesterases
    • Fischmeister, R., et al. 2006. Compartmentation of cyclic nucleotide signaling in the heart: the role of cyclic nucleotide phosphodiesterases. Circ. Res. 99:816-828.
    • (2006) Circ. Res , vol.99 , pp. 816-828
    • Fischmeister, R.1
  • 5
    • 34247105883 scopus 로고    scopus 로고
    • cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: A molecular toolbox for generating compartmentalized cAMP signaling
    • Houslay, M.D., Baillie, G.S., and Maurice, D.H. 2007. cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling. Circ. Res. 100:950-966.
    • (2007) Circ. Res , vol.100 , pp. 950-966
    • Houslay, M.D.1    Baillie, G.S.2    Maurice, D.H.3
  • 6
    • 20044363270 scopus 로고    scopus 로고
    • Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
    • Takimoto, E., et al. 2005. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat. Med. 11:214-222.
    • (2005) Nat. Med , vol.11 , pp. 214-222
    • Takimoto, E.1
  • 7
    • 0035032342 scopus 로고    scopus 로고
    • Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A
    • Osinski, M.T., Rauch, B.H., and Schror, K. 2001. Antimitogenic actions of organic nitrates are potentiated by sildenafil and mediated via activation of protein kinase A. Mol. Pharmacol. 59:1044-1050.
    • (2001) Mol. Pharmacol , vol.59 , pp. 1044-1050
    • Osinski, M.T.1    Rauch, B.H.2    Schror, K.3
  • 8
    • 27344449614 scopus 로고    scopus 로고
    • Keynote review: Phosphodiesterase-4 as a therapeutic target
    • Houslay, M.D., Schafer, P., and Zhang, K.Y. 2005. Keynote review: phosphodiesterase-4 as a therapeutic target. Drug Discov. Today. 10:1503-1519.
    • (2005) Drug Discov. Today , vol.10 , pp. 1503-1519
    • Houslay, M.D.1    Schafer, P.2    Zhang, K.Y.3
  • 9
    • 0024316058 scopus 로고
    • Atrial natriuretic factor-induced egression of cyclic guanosine 3′:5′-monophosphate in cultured vascular smooth muscle and endothelial cells
    • Hamet, P., Pang, S.C., and Tremblay, J. 1989. Atrial natriuretic factor-induced egression of cyclic guanosine 3′:5′-monophosphate in cultured vascular smooth muscle and endothelial cells. J. Biol. Chem. 264:12364-12369.
    • (1989) J. Biol. Chem , vol.264 , pp. 12364-12369
    • Hamet, P.1    Pang, S.C.2    Tremblay, J.3
  • 10
    • 0017376034 scopus 로고
    • Hormone-induced cyclic guanosine monophosphate secretion from guinea pig pancreatic lobules
    • Kapoor, C.L., and Krishna, G. 1977. Hormone-induced cyclic guanosine monophosphate secretion from guinea pig pancreatic lobules. Science. 196:1003-1005.
    • (1977) Science , vol.196 , pp. 1003-1005
    • Kapoor, C.L.1    Krishna, G.2
  • 11
    • 0036451578 scopus 로고    scopus 로고
    • Role of MRP4 and MRP5 in biology and chemotherapy
    • Sampath, J., et al. 2002. Role of MRP4 and MRP5 in biology and chemotherapy. AAPS PharmSci. 4:E14.
    • (2002) AAPS PharmSci , vol.4
    • Sampath, J.1
  • 12
    • 33846681607 scopus 로고    scopus 로고
    • Multidrug resistance-associated proteins 3, 4, and 5
    • Borst, P., de Wolf, C., and van de Wetering, K. 2007. Multidrug resistance-associated proteins 3, 4, and 5. Pflugers Arch. 453:661-673.
    • (2007) Pflugers Arch , vol.453 , pp. 661-673
    • Borst, P.1    de Wolf, C.2    van de Wetering, K.3
  • 13
    • 13844275028 scopus 로고    scopus 로고
    • Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5)
    • Ritter, C.A., et al. 2005. Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5). Drug Metab. Rev. 37:253-278.
    • (2005) Drug Metab. Rev , vol.37 , pp. 253-278
    • Ritter, C.A.1
  • 14
    • 0141648388 scopus 로고    scopus 로고
    • Expression and localization of the multidrug resistance protein 5 (MRP5/ABCC5), a cellular export pump for cyclic nucleotides, in human heart
    • Dazert, P., et al. 2003. Expression and localization of the multidrug resistance protein 5 (MRP5/ABCC5), a cellular export pump for cyclic nucleotides, in human heart. Am. J. Pathol. 163:1567-1577.
    • (2003) Am. J. Pathol , vol.163 , pp. 1567-1577
    • Dazert, P.1
  • 15
    • 0037432640 scopus 로고    scopus 로고
    • Expression of multidrug resistance protein 4 and 5 in the porcine coronary and pulmonary arteries
    • Mitani, A., Nakahara, T., Sakamoto, K., and Ishii, K. 2003. Expression of multidrug resistance protein 4 and 5 in the porcine coronary and pulmonary arteries. Eur. J. Pharmacol. 466:223-224.
    • (2003) Eur. J. Pharmacol , vol.466 , pp. 223-224
    • Mitani, A.1    Nakahara, T.2    Sakamoto, K.3    Ishii, K.4
  • 16
    • 0036229673 scopus 로고    scopus 로고
    • Immunolocalization of multidrug resistance protein 5 in the human genitourinary system
    • Nies, A.T., Spring, H., Thon, W.F., Keppler, D., and Jedlitschky, G. 2002. Immunolocalization of multidrug resistance protein 5 in the human genitourinary system. J. Urol. 167:2271-2275.
    • (2002) J. Urol , vol.167 , pp. 2271-2275
    • Nies, A.T.1    Spring, H.2    Thon, W.F.3    Keppler, D.4    Jedlitschky, G.5
  • 17
    • 0036893815 scopus 로고    scopus 로고
    • Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells
    • Wielinga, P.R., et al. 2002. Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells. Mol. Pharmacol. 62:1321-1331.
    • (2002) Mol. Pharmacol , vol.62 , pp. 1321-1331
    • Wielinga, P.R.1
  • 18
    • 4444377903 scopus 로고    scopus 로고
    • Novel single chain cAMP sensors for receptor-induced signal propagation
    • Nikolaev, V.O., Bunemann, M., Hein, L., Hannawacker, A., and Lohse, M.J. 2004. Novel single chain cAMP sensors for receptor-induced signal propagation. J. Biol. Chem. 279:37215-37218.
    • (2004) J. Biol. Chem , vol.279 , pp. 37215-37218
    • Nikolaev, V.O.1    Bunemann, M.2    Hein, L.3    Hannawacker, A.4    Lohse, M.J.5
  • 19
    • 0035824538 scopus 로고    scopus 로고
    • cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration
    • Klemm, D.J., et al. 2001. cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration. J. Biol. Chem. 276:46132-46141.
    • (2001) J. Biol. Chem , vol.276 , pp. 46132-46141
    • Klemm, D.J.1
  • 20
    • 33745835398 scopus 로고    scopus 로고
    • Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins
    • Deeley, R.G., Westlake, C., and Cole, S.P. 2006. Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins. Physiol. Rev. 86:849-899.
    • (2006) Physiol. Rev , vol.86 , pp. 849-899
    • Deeley, R.G.1    Westlake, C.2    Cole, S.P.3
  • 21
    • 12144257103 scopus 로고    scopus 로고
    • Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites
    • Van Aubel, R.A., Smeets, P.H., van den Heuvel, J.J., and Russel, F.G. 2005. Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites. Am. J. Physiol. Renal Physiol. 288:F327-F333.
    • (2005) Am. J. Physiol. Renal Physiol , vol.288
    • Van Aubel, R.A.1    Smeets, P.H.2    van den Heuvel, J.J.3    Russel, F.G.4
  • 22
    • 0035823559 scopus 로고    scopus 로고
    • Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine
    • Chen, Z.S., Lee, K., and Kruh, G.D. 2001. Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine. J. Biol. Chem. 276:33747-33754.
    • (2001) J. Biol. Chem , vol.276 , pp. 33747-33754
    • Chen, Z.S.1    Lee, K.2    Kruh, G.D.3
  • 23
    • 0036186107 scopus 로고    scopus 로고
    • The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: Putative efflux pump for urinary cAMP and cGMP
    • van Aubel, R.A., Smeets, P.H., Peters, J.G., Bindels, R.J., and Russel, F.G. 2002. The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP. J. Am. Soc. Nephrol. 13:595-603.
    • (2002) J. Am. Soc. Nephrol , vol.13 , pp. 595-603
    • van Aubel, R.A.1    Smeets, P.H.2    Peters, J.G.3    Bindels, R.J.4    Russel, F.G.5
  • 24
    • 0037705377 scopus 로고    scopus 로고
    • Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells
    • Wielinga, P.R., et al. 2003. Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells. J. Biol. Chem. 278:17664-17671.
    • (2003) J. Biol. Chem , vol.278 , pp. 17664-17671
    • Wielinga, P.R.1
  • 25
    • 36249009070 scopus 로고    scopus 로고
    • Spatiotemporal Coupling of cAMP Transporter to CFTR Chloride Channel Function in the Gut Epithelia
    • Li, C., et al. 2007. Spatiotemporal Coupling of cAMP Transporter to CFTR Chloride Channel Function in the Gut Epithelia. Cell. 131:940-951.
    • (2007) Cell , vol.131 , pp. 940-951
    • Li, C.1
  • 26
    • 0038752694 scopus 로고    scopus 로고
    • Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5
    • Reid, G., et al. 2003. Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5. Mol. Pharmacol. 63:1094-1103.
    • (2003) Mol. Pharmacol , vol.63 , pp. 1094-1103
    • Reid, G.1
  • 27
    • 0032879904 scopus 로고    scopus 로고
    • MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs
    • Schuetz, J.D., et al. 1999. MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs. Nat. Med. 5:1048-1051.
    • (1999) Nat. Med , vol.5 , pp. 1048-1051
    • Schuetz, J.D.1
  • 28
    • 33846420624 scopus 로고    scopus 로고
    • Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir
    • Imaoka, T., et al. 2007. Functional involvement of multidrug resistance-associated protein 4 (MRP4/ABCC4) in the renal elimination of the antiviral drugs adefovir and tenofovir. Mol. Pharmacol. 71:619-627.
    • (2007) Mol. Pharmacol , vol.71 , pp. 619-627
    • Imaoka, T.1
  • 29
    • 9444248147 scopus 로고    scopus 로고
    • The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage
    • Jedlitschky, G., et al. 2004. The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage. Blood. 104:3603-3610.
    • (2004) Blood , vol.104 , pp. 3603-3610
    • Jedlitschky, G.1
  • 30
    • 25644452031 scopus 로고    scopus 로고
    • The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways
    • Dodge-Kafka, K.L., et al. 2005. The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways. Nature. 437:574-578.
    • (2005) Nature , vol.437 , pp. 574-578
    • Dodge-Kafka, K.L.1
  • 31
    • 33645743686 scopus 로고    scopus 로고
    • Role of nuclear Ca2+/calmodulin-stimulated phosphodiesterase 1A in vascular smooth muscle cell growth and survival
    • Nagel, D.J., et al. 2006. Role of nuclear Ca2+/calmodulin-stimulated phosphodiesterase 1A in vascular smooth muscle cell growth and survival. Circ. Res. 98:777-784.
    • (2006) Circ. Res , vol.98 , pp. 777-784
    • Nagel, D.J.1
  • 32
    • 0036839744 scopus 로고    scopus 로고
    • Localization of adenylyl cyclase isoforms and G protein-coupled receptors in vascular smooth muscle cells: Expression in caveolin-rich and noncaveolin domains
    • Ostrom, R.S., et al. 2002. Localization of adenylyl cyclase isoforms and G protein-coupled receptors in vascular smooth muscle cells: expression in caveolin-rich and noncaveolin domains. Mol. Pharmacol. 62:983-992.
    • (2002) Mol. Pharmacol , vol.62 , pp. 983-992
    • Ostrom, R.S.1
  • 33
    • 23044496663 scopus 로고    scopus 로고
    • Dynamic association of nitric oxide downstream signaling molecules with endothelial caveolin-1 in rat aorta
    • Linder, A.E., McCluskey, L.P., Cole, K.R., 3rd, Lanning, K.M., and Webb, R.C. 2005. Dynamic association of nitric oxide downstream signaling molecules with endothelial caveolin-1 in rat aorta. J. Pharmacol. Exp. Ther. 314:9-15.
    • (2005) J. Pharmacol. Exp. Ther , vol.314 , pp. 9-15
    • Linder, A.E.1    McCluskey, L.P.2    Cole 3rd, K.R.3    Lanning, K.M.4    Webb, R.C.5
  • 34
    • 0030835725 scopus 로고    scopus 로고
    • Activation of cAMP-PKA signaling in vivo inhibits smooth muscle cell proliferation induced by vascular injury
    • Indolfi, C., et al. 1997. Activation of cAMP-PKA signaling in vivo inhibits smooth muscle cell proliferation induced by vascular injury. Nat. Med. 3:775-779.
    • (1997) Nat. Med , vol.3 , pp. 775-779
    • Indolfi, C.1
  • 35
    • 0026472158 scopus 로고
    • Inhibition of proliferation, but not of Ca2+ mobilization, by cyclic AMP and GMP in rabbit aortic smooth-muscle cells
    • Assender, J.W., Southgate, K.M., Hallett, M.B., and Newby, A.C. 1992. Inhibition of proliferation, but not of Ca2+ mobilization, by cyclic AMP and GMP in rabbit aortic smooth-muscle cells. Biochem. J. 288:527-532.
    • (1992) Biochem. J , vol.288 , pp. 527-532
    • Assender, J.W.1    Southgate, K.M.2    Hallett, M.B.3    Newby, A.C.4
  • 36
    • 0025340170 scopus 로고
    • Serum-induced proliferation of rabbit aortic smooth muscle cells from the contractile state is inhibited by 8-Br-cAMP but not 8-Br-cGMP
    • Southgate, K., and Newby, A.C. 1990. Serum-induced proliferation of rabbit aortic smooth muscle cells from the contractile state is inhibited by 8-Br-cAMP but not 8-Br-cGMP. Atherosclerosis. 82:113-123.
    • (1990) Atherosclerosis , vol.82 , pp. 113-123
    • Southgate, K.1    Newby, A.C.2
  • 37
    • 0037129906 scopus 로고    scopus 로고
    • Overexpression of a constitutively active protein kinase G mutant reduces neointima formation and in-stent restenosis
    • Sinnaeve, P., et al. 2002. Overexpression of a constitutively active protein kinase G mutant reduces neointima formation and in-stent restenosis. Circulation. 105:2911-2916.
    • (2002) Circulation , vol.105 , pp. 2911-2916
    • Sinnaeve, P.1
  • 38
    • 0027986509 scopus 로고
    • Inhibition of smooth muscle cell growth by nitric oxide and activation of cAMP-dependent protein kinase by cGMP
    • Cornwell, T.L., Arnold, E., Boerth, N.J., and Lincoln, T.M. 1994. Inhibition of smooth muscle cell growth by nitric oxide and activation of cAMP-dependent protein kinase by cGMP. Am. J. Physiol. 267:C1405-C1413.
    • (1994) Am. J. Physiol , vol.267
    • Cornwell, T.L.1    Arnold, E.2    Boerth, N.J.3    Lincoln, T.M.4
  • 39
    • 33745050483 scopus 로고    scopus 로고
    • Altered S-phase kinase-associated protein-2 levels are a major mediator of cyclic nucleotide-induced inhibition of vascular smooth muscle cell proliferation
    • Wu, Y.J., Bond, M., Sala-Newby, G.B., and Newby, A.C. 2006. Altered S-phase kinase-associated protein-2 levels are a major mediator of cyclic nucleotide-induced inhibition of vascular smooth muscle cell proliferation. Circ. Res. 98:1141-1150.
    • (2006) Circ. Res , vol.98 , pp. 1141-1150
    • Wu, Y.J.1    Bond, M.2    Sala-Newby, G.B.3    Newby, A.C.4
  • 40
    • 0041414284 scopus 로고    scopus 로고
    • Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells
    • Aizawa, T., et al. 2003. Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells. Circ. Res. 93:406-413.
    • (2003) Circ. Res , vol.93 , pp. 406-413
    • Aizawa, T.1
  • 41
    • 2942685631 scopus 로고    scopus 로고
    • Caveolae and caveolins in the cardiovascular system
    • Gratton, J.P., Bernatchez, P., and Sessa, W.C. 2004. Caveolae and caveolins in the cardiovascular system. Circ. Res. 94:1408-1417.
    • (2004) Circ. Res , vol.94 , pp. 1408-1417
    • Gratton, J.P.1    Bernatchez, P.2    Sessa, W.C.3
  • 43
    • 36349015332 scopus 로고    scopus 로고
    • Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway
    • Maher, J.M., et al. 2007. Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway. Hepatology. 46:1597-1610.
    • (2007) Hepatology , vol.46 , pp. 1597-1610
    • Maher, J.M.1
  • 44
    • 0037421504 scopus 로고    scopus 로고
    • Clinical results with AGI-1067: A novel antioxidant vascular protectant
    • Tardif, J.C. 2003. Clinical results with AGI-1067: a novel antioxidant vascular protectant. Am. J. Cardiol. 91:41A-49A.
    • (2003) Am. J. Cardiol , vol.91
    • Tardif, J.C.1
  • 45
    • 34247618157 scopus 로고    scopus 로고
    • Phosphorylation of the cyclic AMP response element binding protein mediates transforming growth factor beta-induced downregulation of cyclin A in vascular smooth muscle cells
    • Kamiya, K., et al. 2007. Phosphorylation of the cyclic AMP response element binding protein mediates transforming growth factor beta-induced downregulation of cyclin A in vascular smooth muscle cells. Mol. Cell. Biol. 27:3489-3498.
    • (2007) Mol. Cell. Biol , vol.27 , pp. 3489-3498
    • Kamiya, K.1
  • 46
    • 0043268711 scopus 로고    scopus 로고
    • Cyclic AMP response element-binding protein mediates reactive oxygen species-induced c-fos expression
    • Ichiki, T., et al. 2003. Cyclic AMP response element-binding protein mediates reactive oxygen species-induced c-fos expression. Hypertension. 42:177-183.
    • (2003) Hypertension , vol.42 , pp. 177-183
    • Ichiki, T.1
  • 47
    • 0035824659 scopus 로고    scopus 로고
    • Diabetes-related changes in cAMP response element-binding protein content enhance smooth muscle cell proliferation and migration
    • Watson, P.A., Nesterova, A., Burant, C.F., Klemm, D.J., and Reusch, J.E. 2001. Diabetes-related changes in cAMP response element-binding protein content enhance smooth muscle cell proliferation and migration. J. Biol. Chem. 276:46142-46150.
    • (2001) J. Biol. Chem , vol.276 , pp. 46142-46150
    • Watson, P.A.1    Nesterova, A.2    Burant, C.F.3    Klemm, D.J.4    Reusch, J.E.5
  • 48
    • 2642560209 scopus 로고    scopus 로고
    • Store-operated Ca2+ entry activates the CREB transcription factor in vascular smooth muscle
    • Pulver, R.A., Rose-Curtis, P., Roe, M.W., Wellman, G.C., and Lounsbury, K.M. 2004. Store-operated Ca2+ entry activates the CREB transcription factor in vascular smooth muscle. Circ. Res. 94:1351-1358.
    • (2004) Circ. Res , vol.94 , pp. 1351-1358
    • Pulver, R.A.1    Rose-Curtis, P.2    Roe, M.W.3    Wellman, G.C.4    Lounsbury, K.M.5
  • 49
    • 0038390084 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and calcium-activated transcription pathways are required for VLDL-induced smooth muscle cell proliferation
    • Lipskaia, L., et al. 2003. Phosphatidylinositol 3-kinase and calcium-activated transcription pathways are required for VLDL-induced smooth muscle cell proliferation. Circ. Res. 92:1115-1122.
    • (2003) Circ. Res , vol.92 , pp. 1115-1122
    • Lipskaia, L.1
  • 50
    • 0042531890 scopus 로고    scopus 로고
    • MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2′,3′-dideoxycytidine and 9′-(2′-phosphonylmethoxyethyl) adenine
    • Guo, Y., et al. 2003. MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2′,3′-dideoxycytidine and 9′-(2′-phosphonylmethoxyethyl) adenine. J. Biol. Chem. 278:29509-29514.
    • (2003) J. Biol. Chem , vol.278 , pp. 29509-29514
    • Guo, Y.1
  • 51
    • 0036851826 scopus 로고    scopus 로고
    • Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies
    • Dzau, V.J., Braun-Dullaeus, R.C., and Sedding, D.G. 2002. Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies. Nat. Med. 8:1249-1256.
    • (2002) Nat. Med , vol.8 , pp. 1249-1256
    • Dzau, V.J.1    Braun-Dullaeus, R.C.2    Sedding, D.G.3
  • 52
    • 0031670934 scopus 로고    scopus 로고
    • Cardiovascular disease increasing in developing countries
    • Novak, K. 1998. Cardiovascular disease increasing in developing countries. Nat. Med. 4:989-990.
    • (1998) Nat. Med , vol.4 , pp. 989-990
    • Novak, K.1
  • 53
    • 4644290657 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension
    • Humbert, M., Sitbon, O., and Simonneau, G. 2004. Treatment of pulmonary arterial hypertension. N. Engl. J. Med. 351:1425-1436.
    • (2004) N. Engl. J. Med , vol.351 , pp. 1425-1436
    • Humbert, M.1    Sitbon, O.2    Simonneau, G.3
  • 54
    • 4344632950 scopus 로고    scopus 로고
    • Mrp4 confers resistance to topotecan and protects the brain from chemotherapy
    • Leggas, M., et al. 2004. Mrp4 confers resistance to topotecan and protects the brain from chemotherapy. Mol. Cell. Biol. 24:7612-7621.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 7612-7621
    • Leggas, M.1
  • 55
    • 0032861251 scopus 로고    scopus 로고
    • Expression of PKA inhibitor (PKI) gene abolishes cAMP-mediated protection to endothelial barrier dysfunction
    • Lum, H., et al. 1999. Expression of PKA inhibitor (PKI) gene abolishes cAMP-mediated protection to endothelial barrier dysfunction. Am. J. Physiol. 277:C580-C588.
    • (1999) Am. J. Physiol , vol.277
    • Lum, H.1
  • 56
    • 24744448691 scopus 로고    scopus 로고
    • Sarco/endoplasmic reticulum Ca2+-ATPase gene transfer reduces vascular smooth muscle cell proliferation and neointima formation in the rat
    • Lipskaia, L., et al. 2005. Sarco/endoplasmic reticulum Ca2+-ATPase gene transfer reduces vascular smooth muscle cell proliferation and neointima formation in the rat. Circ. Res. 97:488-495.
    • (2005) Circ. Res , vol.97 , pp. 488-495
    • Lipskaia, L.1
  • 57
    • 0034023214 scopus 로고    scopus 로고
    • Intracellular Ca(2+) handling in vascular smooth muscle cells is affected by proliferation
    • Vallot, O., et al. 2000. Intracellular Ca(2+) handling in vascular smooth muscle cells is affected by proliferation. Arterioscler. Thromb. Vasc. Biol. 20:1225-1235.
    • (2000) Arterioscler. Thromb. Vasc. Biol , vol.20 , pp. 1225-1235
    • Vallot, O.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.