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Volumn 80, Issue 5, 2006, Pages 1067-1075

The glutamate-glutamine cycle as an inducible, protective face of macrophage activation

Author keywords

Aids; Inflammation; Microglia; Neuroprotection; Neurotoxicity; TSE

Indexed keywords

AMINO ACID; CYSTINE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; VIRUS PROTEIN;

EID: 33750481898     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0306153     Document Type: Review
Times cited : (62)

References (127)
  • 1
    • 0035912198 scopus 로고    scopus 로고
    • Pathways to neuronal injury and apoptosis in HIV-associated dementia
    • Kaul, M., Garden, G. A., Lipton, S. A. (2001) Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410, 988-994.
    • (2001) Nature , vol.410 , pp. 988-994
    • Kaul, M.1    Garden, G.A.2    Lipton, S.A.3
  • 2
    • 22744455058 scopus 로고    scopus 로고
    • HIV-1 infection and AIDS: Consequences for the central nervous system
    • Kaul, M., Zheng, J., Okamoto, S., Gendelman, H. E., Lipton, S. A. (2005) HIV-1 infection and AIDS: consequences for the central nervous system. Cell Death Differ. 12 (Suppl. 1), 878-892.
    • (2005) Cell Death Differ. , vol.12 , Issue.SUPPL. 1 , pp. 878-892
    • Kaul, M.1    Zheng, J.2    Okamoto, S.3    Gendelman, H.E.4    Lipton, S.A.5
  • 4
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurologic disorders
    • Lipton, S. A., Rosenberg, P. A. (1994) Excitatory amino acids as a final common pathway for neurologic disorders. N. Engl. J. Med. 330, 613-622.
    • (1994) N. Engl. J. Med. , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 5
    • 0029897979 scopus 로고    scopus 로고
    • Investigation on the expression of major histocompatibility complex class II and cytokines and detection of HIV-1 DNA within brains of asymptomatic and symptomatic HIV-1-positive patients
    • An, S. F., Ciardi, A., Giometto, B., Scaravilli, T., Gray, F., Scaravilli, F. (1996) Investigation on the expression of major histocompatibility complex class II and cytokines and detection of HIV-1 DNA within brains of asymptomatic and symptomatic HIV-1-positive patients. Acta Neuropathol. (Berl.) 91, 494-503.
    • (1996) Acta Neuropathol. (Berl.) , vol.91 , pp. 494-503
    • An, S.F.1    Ciardi, A.2    Giometto, B.3    Scaravilli, T.4    Gray, F.5    Scaravilli, F.6
  • 6
    • 0027976315 scopus 로고
    • Immunohistochemical changes and PCR detection of HIV provirus DNA in brains of asymptomatic HIV-positive patients
    • Sinclair, E., Gray, F., Ciardi, A., Scaravilli, F. (1994) Immunohistochemical changes and PCR detection of HIV provirus DNA in brains of asymptomatic HIV-positive patients. J. Neuropathol. Exp. Neurol. 53, 43-50.
    • (1994) J. Neuropathol. Exp. Neurol. , vol.53 , pp. 43-50
    • Sinclair, E.1    Gray, F.2    Ciardi, A.3    Scaravilli, F.4
  • 7
    • 0027360522 scopus 로고
    • A review of neuronal damage in human immunodeficiency virus infection: Its assessment, possible mechanism and relationship to dementia
    • Everall, I., Luthert, P., Lantos, P. (1993) A review of neuronal damage in human immunodeficiency virus infection: its assessment, possible mechanism and relationship to dementia. J. Neuropathol. Exp. Neurol. 52, 561-566.
    • (1993) J. Neuropathol. Exp. Neurol. , vol.52 , pp. 561-566
    • Everall, I.1    Luthert, P.2    Lantos, P.3
  • 8
    • 0021330769 scopus 로고
    • Glutamate: A neurotransmitter in mammalian brain
    • Fonnum, F. (1984) Glutamate: a neurotransmitter in mammalian brain. J. Neurochem. 42, 1-11.
    • (1984) J. Neurochem. , vol.42 , pp. 1-11
    • Fonnum, F.1
  • 9
    • 0028841367 scopus 로고
    • Physiological release of excitatory amino acids
    • Fillenz, M. (1995) Physiological release of excitatory amino acids. Behav. Brain Res. 71, 51-67.
    • (1995) Behav. Brain Res. , vol.71 , pp. 51-67
    • Fillenz, M.1
  • 10
    • 0021031723 scopus 로고
    • Quinolinic acid evokes [3H]acetylcholine release in striatal slices: Mediation by NMDA-type excitatory amino acid receptors
    • Lehmann, J., Schaefer, P., Ferkany, J. W., Coyle, J, T. (1983) Quinolinic acid evokes [3H]acetylcholine release in striatal slices: mediation by NMDA-type excitatory amino acid receptors. Eur. J. Pharmacol. 96, 111-115.
    • (1983) Eur. J. Pharmacol. , vol.96 , pp. 111-115
    • Lehmann, J.1    Schaefer, P.2    Ferkany, J.W.3    Coyle, J.T.4
  • 11
    • 0021125414 scopus 로고
    • Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death
    • Rothman, S. (1984) Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death. J. Neurosci. 4, 1884-1891.
    • (1984) J. Neurosci. , vol.4 , pp. 1884-1891
    • Rothman, S.1
  • 12
    • 0021880922 scopus 로고
    • The neurotoxicity of excitatory amino acids is produced by passive chloride influx
    • Rothman, S. M. (1985) The neurotoxicity of excitatory amino acids is produced by passive chloride influx. J. Neurosci. 5, 1483-1489.
    • (1985) J. Neurosci. , vol.5 , pp. 1483-1489
    • Rothman, S.M.1
  • 13
    • 0026544324 scopus 로고
    • Metabolic compartmentation of glutamate and glutamine: Morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum
    • Ottersen, O. P., Zhang, N., Walberg, F. (1992) Metabolic compartmentation of glutamate and glutamine: morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum. Neuroscience 46, 519-534.
    • (1992) Neuroscience , vol.46 , pp. 519-534
    • Ottersen, O.P.1    Zhang, N.2    Walberg, F.3
  • 14
    • 0027483397 scopus 로고
    • Expression cloning of a rat glutamate transporter
    • Tanaka, K. (1993) Expression cloning of a rat glutamate transporter. Neurosci. Res. 16, 149-153.
    • (1993) Neurosci. Res. , vol.16 , pp. 149-153
    • Tanaka, K.1
  • 15
    • 0026489330 scopus 로고
    • Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain
    • Storck, T., Schulte, S., Hofmann, K., Stoffel, W. (1992) Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain. Proc. Natl. Acad. Sci. USA 89, 10955-10959.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 10955-10959
    • Storck, T.1    Schulte, S.2    Hofmann, K.3    Stoffel, W.4
  • 17
    • 0026458124 scopus 로고
    • Primary structure and functional characterization of a high-affinity glutamate transporter
    • Kanai, Y., Hediger, M. A. (1992) Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360, 467-471.
    • (1992) Nature , vol.360 , pp. 467-471
    • Kanai, Y.1    Hediger, M.A.2
  • 18
    • 0029076899 scopus 로고
    • An excitatory amino-acid transporter with properties of a ligand-gated chloride channel
    • Fairman, W. A., Vandenberg, R. J., Arriza, J. L., Kavanaugh, M. P., Amara, S. G. (1995) An excitatory amino-acid transporter with properties of a ligand-gated chloride channel. Nature 375, 599-603.
    • (1995) Nature , vol.375 , pp. 599-603
    • Fairman, W.A.1    Vandenberg, R.J.2    Arriza, J.L.3    Kavanaugh, M.P.4    Amara, S.G.5
  • 19
    • 0030932152 scopus 로고    scopus 로고
    • Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance
    • Arriza, J. L., Eliasof, S., Kavanaugh, M. P., Amara, S. G. (1997) Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance. Proc. Natl. Acad. Sci. USA 94, 4155-4160.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 4155-4160
    • Arriza, J.L.1    Eliasof, S.2    Kavanaugh, M.P.3    Amara, S.G.4
  • 21
    • 0030840881 scopus 로고    scopus 로고
    • High affinity glutamate transporters: Regulation of expression and activity
    • Gegelashvili, G., Schousboe, A. (1997) High affinity glutamate transporters: regulation of expression and activity. Mol. Pharmacol. 52, 6-15.
    • (1997) Mol. Pharmacol. , vol.52 , pp. 6-15
    • Gegelashvili, G.1    Schousboe, A.2
  • 24
    • 0027376769 scopus 로고
    • Nonvesicular release of neurotransmitter
    • Attwell, D., Barbour, B., Szatkowski, M. (1993) Nonvesicular release of neurotransmitter. Neuron 11, 401-407.
    • (1993) Neuron , vol.11 , pp. 401-407
    • Attwell, D.1    Barbour, B.2    Szatkowski, M.3
  • 25
    • 0017622252 scopus 로고
    • Muller cell localization of glutamine synthetase in rat retina
    • Riepe, R. E., Norenburg, M. D. (1977) Muller cell localization of glutamine synthetase in rat retina. Nature 268, 654-655.
    • (1977) Nature , vol.268 , pp. 654-655
    • Riepe, R.E.1    Norenburg, M.D.2
  • 26
    • 0017579832 scopus 로고
    • Glutamine synthetase: Glial localization in brain
    • Martinez-Hernandez, A., Bell, K. P., Norenberg, M. D. (1977) Glutamine synthetase: glial localization in brain. Science 195, 1356-1358.
    • (1977) Science , vol.195 , pp. 1356-1358
    • Martinez-Hernandez, A.1    Bell, K.P.2    Norenberg, M.D.3
  • 27
    • 0018776955 scopus 로고
    • Distribution of glutamine synthetase in the rat central nervous system
    • Norenberg, M. D. (1979) Distribution of glutamine synthetase in the rat central nervous system. J. Histochem. Cytochem. 27, 756-762.
    • (1979) J. Histochem. Cytochem. , vol.27 , pp. 756-762
    • Norenberg, M.D.1
  • 28
    • 0018382256 scopus 로고
    • Fine structural localization of glutamine synthetase in astrocytes of rat brain
    • Norenberg, M. D., Martinez-Hernandez, A. (1979) Fine structural localization of glutamine synthetase in astrocytes of rat brain. Brain Res. 161, 303-310.
    • (1979) Brain Res. , vol.161 , pp. 303-310
    • Norenberg, M.D.1    Martinez-Hernandez, A.2
  • 29
    • 0025878379 scopus 로고
    • Astroglial processes around identified glutamatergic synapses contain glutamine synthetase: Evidence for transmitter degradation
    • Derouiche, A., Frotscher, M. (1991) Astroglial processes around identified glutamatergic synapses contain glutamine synthetase: evidence for transmitter degradation. Brain Res. 552, 346-350.
    • (1991) Brain Res. , vol.552 , pp. 346-350
    • Derouiche, A.1    Frotscher, M.2
  • 30
    • 0029859733 scopus 로고    scopus 로고
    • Spatial relationship of lectin-labeled extracellular matrix and glutamine synthetase-immunoreactive astrocytes in rat cortical forebrain regions
    • Derouiche, A., Hartig, W., Brauer, K., Bruckner, G. (1996) Spatial relationship of lectin-labeled extracellular matrix and glutamine synthetase-immunoreactive astrocytes in rat cortical forebrain regions. J. Anat. 189, 363-372.
    • (1996) J. Anat. , vol.189 , pp. 363-372
    • Derouiche, A.1    Hartig, W.2    Brauer, K.3    Bruckner, G.4
  • 31
    • 0029120602 scopus 로고
    • Coincidence of L-glutamate/L-aspartate transporter (GLAST) and glutamine synthetase (GS) immunoreactions in retinal glia: Evidence for coupling of GLAST and GS in transmitter clearance
    • Derouiche, A., Rauen, T. (1995) Coincidence of L-glutamate/L-aspartate transporter (GLAST) and glutamine synthetase (GS) immunoreactions in retinal glia: evidence for coupling of GLAST and GS in transmitter clearance. J. Neurosci. Res. 42, 131-143.
    • (1995) J. Neurosci. Res. , vol.42 , pp. 131-143
    • Derouiche, A.1    Rauen, T.2
  • 32
    • 0033598956 scopus 로고    scopus 로고
    • Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission
    • Chaudhry, F. A., Reimer, R. J., Krizaj, D., Barber, D., Storm-Mathisen, J., Copenhagen, D. R., Edwards, R. H. (1999) Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission. Cell 99, 769-780.
    • (1999) Cell , vol.99 , pp. 769-780
    • Chaudhry, F.A.1    Reimer, R.J.2    Krizaj, D.3    Barber, D.4    Storm-Mathisen, J.5    Copenhagen, D.R.6    Edwards, R.H.7
  • 33
    • 0034724370 scopus 로고    scopus 로고
    • Identification and characterization of an amino acid transporter expressed differentially in liver
    • Gu, S., Roderick, H. L., Camacho, P., Jiang, J. X. (2000) Identification and characterization of an amino acid transporter expressed differentially in liver. Proc. Natl. Acad. Sci. USA 97, 3230-3235.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 3230-3235
    • Gu, S.1    Roderick, H.L.2    Camacho, P.3    Jiang, J.X.4
  • 35
    • 0034635496 scopus 로고    scopus 로고
    • Cloning and functional identification of a neuronal glutamine transporter
    • Varoqui, H., Zhu, H., Yao, D., Ming, H., Erickson, J. D. (2000) Cloning and functional identification of a neuronal glutamine transporter. J. Biol. Chem. 275, 4049-4054.
    • (2000) J. Biol. Chem. , vol.275 , pp. 4049-4054
    • Varoqui, H.1    Zhu, H.2    Yao, D.3    Ming, H.4    Erickson, J.D.5
  • 36
    • 0038469628 scopus 로고    scopus 로고
    • Transfer of glutamine between astrocytes and neurons
    • Broer, S., Brookes, N. (2001) Transfer of glutamine between astrocytes and neurons. J. Neurochem. 77, 705-719.
    • (2001) J. Neurochem. , vol.77 , pp. 705-719
    • Broer, S.1    Brookes, N.2
  • 37
    • 0034019630 scopus 로고    scopus 로고
    • Compartmentation of brain glutamate metabolism in neurons and glia
    • Daikhin, Y., Yudkoff, M. (2000) Compartmentation of brain glutamate metabolism in neurons and glia. J. Nutr. 130, 1026S-1031S.
    • (2000) J. Nutr. , vol.130
    • Daikhin, Y.1    Yudkoff, M.2
  • 39
    • 0034648770 scopus 로고    scopus 로고
    • Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons
    • Takamori, S., Rhee, J. S., Rosenmund, C., Jahn, R. (2000) Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons. Nature 407, 189-194.
    • (2000) Nature , vol.407 , pp. 189-194
    • Takamori, S.1    Rhee, J.S.2    Rosenmund, C.3    Jahn, R.4
  • 40
    • 0027463358 scopus 로고
    • Brain glia release factors with opposing actions upon neuronal survival
    • Giulian, D., Vaca, K., Corpuz, M. (1993) Brain glia release factors with opposing actions upon neuronal survival. J. Neurosci. 13, 29-37.
    • (1993) J. Neurosci. , vol.13 , pp. 29-37
    • Giulian, D.1    Vaca, K.2    Corpuz, M.3
  • 42
    • 0035449358 scopus 로고    scopus 로고
    • Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity
    • Bal-Price, A., Brown, G. C. (2001) Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity. J. Neurosci. 21, 6480-6491.
    • (2001) J. Neurosci. , vol.21 , pp. 6480-6491
    • Bal-Price, A.1    Brown, G.C.2
  • 43
    • 14944385354 scopus 로고    scopus 로고
    • β-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor α and NMDA receptors
    • Floden, A. M., Li, S., Combs, C. K. (2005) β-Amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor α and NMDA receptors. J. Neurosci. 25, 2566-2575.
    • (2005) J. Neurosci. , vol.25 , pp. 2566-2575
    • Floden, A.M.1    Li, S.2    Combs, C.K.3
  • 44
    • 15444363122 scopus 로고    scopus 로고
    • Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport
    • Takeuchi, H., Mizuno, T., Zhang, G., Wang, J., Kawanokuchi, J., Kuno, R., Suzumura, A. (2005) Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport. J. Biol. Chem. 280, 10444-10454.
    • (2005) J. Biol. Chem. , vol.280 , pp. 10444-10454
    • Takeuchi, H.1    Mizuno, T.2    Zhang, G.3    Wang, J.4    Kawanokuchi, J.5    Kuno, R.6    Suzumura, A.7
  • 45
    • 0025609978 scopus 로고
    • Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1
    • Giulian, D., Vaca, K., Noonan, C. A. (1990) Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science 250, 1593-1596.
    • (1990) Science , vol.250 , pp. 1593-1596
    • Giulian, D.1    Vaca, K.2    Noonan, C.A.3
  • 46
    • 0032801853 scopus 로고    scopus 로고
    • Monocytic cells secrete factors that evoke excitatory synaptic activity in rat hippocampal cultures
    • Hegg, C. C., Thayer, S. A. (1999) Monocytic cells secrete factors that evoke excitatory synaptic activity in rat hippocampal cultures. Eur. J. Pharmacol. 385, 231-237.
    • (1999) Eur. J. Pharmacol. , vol.385 , pp. 231-237
    • Hegg, C.C.1    Thayer, S.A.2
  • 47
    • 0037426561 scopus 로고    scopus 로고
    • Activation of NR1a/NR2B receptors by monocyte-derived macrophage secretory products: Implications for human immunodeficiency virus type one-associated dementia
    • Xiong, H., McCabe, L., Skifter, D., Monaghan, D. T., Gendelman, H. E. (2003) Activation of NR1a/NR2B receptors by monocyte-derived macrophage secretory products: implications for human immunodeficiency virus type one-associated dementia. Neurosci. Lett. 341, 246-250.
    • (2003) Neurosci. Lett. , vol.341 , pp. 246-250
    • Xiong, H.1    McCabe, L.2    Skifter, D.3    Monaghan, D.T.4    Gendelman, H.E.5
  • 49
    • 0035162001 scopus 로고    scopus 로고
    • HIV-1 infected and immune competent mononuclear phagocytes induce quantitative alterations in neuronal dendritic arbor: Relevance for HIV-1-associated dementia
    • Zheng, J., Thylin, M. R., Cotter, R. L., Lopez, A. L., Ghorpade, A., Persidsky, Y., Xiong, H., Leisman, G. B., Che, M. H., Gendelman, H. E. (2001) HIV-1 infected and immune competent mononuclear phagocytes induce quantitative alterations in neuronal dendritic arbor: relevance for HIV-1-associated dementia. Neurotox. Res. 3, 443-459.
    • (2001) Neurotox. Res. , vol.3 , pp. 443-459
    • Zheng, J.1    Thylin, M.R.2    Cotter, R.L.3    Lopez, A.L.4    Ghorpade, A.5    Persidsky, Y.6    Xiong, H.7    Leisman, G.B.8    Che, M.H.9    Gendelman, H.E.10
  • 51
    • 0346102601 scopus 로고    scopus 로고
    • Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: Linkage to HIV-1 associated dementia
    • Zhao, J., Lopez, A. L., Erichsen, D., Herek, S., Cotter, R. L., Curthoys, N. P., Zheng, J. (2004) Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: linkage to HIV-1 associated dementia. J. Neurochem. 88, 169-180.
    • (2004) J. Neurochem. , vol.88 , pp. 169-180
    • Zhao, J.1    Lopez, A.L.2    Erichsen, D.3    Herek, S.4    Cotter, R.L.5    Curthoys, N.P.6    Zheng, J.7
  • 52
    • 0034652701 scopus 로고    scopus 로고
    • Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro
    • Flavin, M. P., Zhao, G., Ho, L. T. (2000) Microglial tissue plasminogen activator (tPA) triggers neuronal apoptosis in vitro. Glia 29, 347-354.
    • (2000) Glia , vol.29 , pp. 347-354
    • Flavin, M.P.1    Zhao, G.2    Ho, L.T.3
  • 54
    • 0038348526 scopus 로고    scopus 로고
    • Microglial functions and proteases
    • Nakanishi, H. (2003) Microglial functions and proteases. Mol. Neurobiol. 27, 163-176.
    • (2003) Mol. Neurobiol. , vol.27 , pp. 163-176
    • Nakanishi, H.1
  • 55
    • 0042039559 scopus 로고    scopus 로고
    • Microglial proteases: Strategic targets for neuroprotective agents
    • Nakanishi, H. (2003) Microglial proteases: strategic targets for neuroprotective agents. Curr. Neuropharmacol. 1, 99-108.
    • (2003) Curr. Neuropharmacol. , vol.1 , pp. 99-108
    • Nakanishi, H.1
  • 56
    • 13844262664 scopus 로고    scopus 로고
    • Interleukin-1β enhances NMDA receptor-mediated current but inhibits excitatory synaptic transmission
    • Yang, S., Liu, Z. W., Wen, L., Qiao, H. F., Zhou, W. X., Zhang, Y. X. (2005) Interleukin-1β enhances NMDA receptor-mediated current but inhibits excitatory synaptic transmission. Brain Res. 1034, 172-179.
    • (2005) Brain Res. , vol.1034 , pp. 172-179
    • Yang, S.1    Liu, Z.W.2    Wen, L.3    Qiao, H.F.4    Zhou, W.X.5    Zhang, Y.X.6
  • 57
    • 0035896439 scopus 로고    scopus 로고
    • Interleukin-2 modulates N-methyl-D-aspartate receptors of native mesolimbic neurons
    • Ye, J. H., Tao, L., Zalcman, S. S. (2001) Interleukin-2 modulates N-methyl-D-aspartate receptors of native mesolimbic neurons. Brain Res. 894, 241-248.
    • (2001) Brain Res. , vol.894 , pp. 241-248
    • Ye, J.H.1    Tao, L.2    Zalcman, S.S.3
  • 58
    • 33645979933 scopus 로고    scopus 로고
    • Potentiation of the NMDA receptor-mediated responses through the activation of the glycine site by microglia secreting soluble factors
    • Hayashi, Y., Ishibashi, H., Hashimoto, K., Nakanishi, H. (2006) Potentiation of the NMDA receptor-mediated responses through the activation of the glycine site by microglia secreting soluble factors. Glia 53, 660-668.
    • (2006) Glia , vol.53 , pp. 660-668
    • Hayashi, Y.1    Ishibashi, H.2    Hashimoto, K.3    Nakanishi, H.4
  • 59
    • 0025992743 scopus 로고
    • Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome
    • Heyes, M. P., Brew, B., Martin, A., Markey, S. P., Price, R. W., Bhalla, R. B., Salazar, A. (1991) Cerebrospinal fluid quinolinic acid concentrations are increased in acquired immune deficiency syndrome. Adv. Exp. Med. Biol. 294, 687-690.
    • (1991) Adv. Exp. Med. Biol. , vol.294 , pp. 687-690
    • Heyes, M.P.1    Brew, B.2    Martin, A.3    Markey, S.P.4    Price, R.W.5    Bhalla, R.B.6    Salazar, A.7
  • 60
    • 1042302739 scopus 로고    scopus 로고
    • Expression of the kynurenine pathway enzymes in human microglia and macrophages
    • Guillemin, G. J., Smith, D. G., Smythe, G. A., Armati, P. J., Brew, B. J. (2003) Expression of the kynurenine pathway enzymes in human microglia and macrophages. Adv. Exp. Med. Biol. 527, 105-112.
    • (2003) Adv. Exp. Med. Biol. , vol.527 , pp. 105-112
    • Guillemin, G.J.1    Smith, D.G.2    Smythe, G.A.3    Armati, P.J.4    Brew, B.J.5
  • 63
    • 0033006151 scopus 로고    scopus 로고
    • Glutamate release from microglia via glutamate transporter is enhanced by amyloid-β peptide
    • Noda, M., Nakanishi, H., Akaike, N. (1999) Glutamate release from microglia via glutamate transporter is enhanced by amyloid-β peptide. Neuroscience 92, 1465-1474.
    • (1999) Neuroscience , vol.92 , pp. 1465-1474
    • Noda, M.1    Nakanishi, H.2    Akaike, N.3
  • 64
    • 0034728639 scopus 로고    scopus 로고
    • Glutamate transporter GLT-1 is highly expressed in activated microglia following facial nerve axotomy
    • Lopez-Redondo, F., Nakajima, K., Honda, S., Kohsaka, S. (2000) Glutamate transporter GLT-1 is highly expressed in activated microglia following facial nerve axotomy. Brain Res. Mol. Brain Res. 76, 429-435.
    • (2000) Brain Res. Mol. Brain Res. , vol.76 , pp. 429-435
    • Lopez-Redondo, F.1    Nakajima, K.2    Honda, S.3    Kohsaka, S.4
  • 69
    • 0028958939 scopus 로고
    • Differential expression of two glial glutamate transporters in the rat brain: Quantitative and immunocytochemical observations
    • Lehre, K. P., Levy, L. M., Ottersen, O. P., Storm-Mathisen, J., Danbolt, N. C. (1995) Differential expression of two glial glutamate transporters in the rat brain: quantitative and immunocytochemical observations. J. Neurosci. 15, 1835-1853.
    • (1995) J. Neurosci. , vol.15 , pp. 1835-1853
    • Lehre, K.P.1    Levy, L.M.2    Ottersen, O.P.3    Storm-Mathisen, J.4    Danbolt, N.C.5
  • 70
    • 18344403959 scopus 로고    scopus 로고
    • Expression of excitatory amino acid transporter-1 in brain macrophages and microglia of HIV-infected patients. A neuroprotective role for activated microglia?
    • Vallat-Decouvelaere, A. V., Chretien, F., Gras, G., Le Pavec, G., Dormont, D., Gray, F. (2003) Expression of excitatory amino acid transporter-1 in brain macrophages and microglia of HIV-infected patients. A neuroprotective role for activated microglia? J. Neuropathol. Exp. Neurol. 62, 475-485.
    • (2003) J. Neuropathol. Exp. Neurol. , vol.62 , pp. 475-485
    • Vallat-Decouvelaere, A.V.1    Chretien, F.2    Gras, G.3    Le Pavec, G.4    Dormont, D.5    Gray, F.6
  • 71
    • 0035111243 scopus 로고    scopus 로고
    • Absence of detectable IL-1β production in murine prion disease: A model of chronic neurodegeneration
    • Walsh, D. T., Betmouni, S., Perry, V. H. (2001) Absence of detectable IL-1β production in murine prion disease: a model of chronic neurodegeneration. J. Neuropathol. Exp. Neurol. 60, 173-182.
    • (2001) J. Neuropathol. Exp. Neurol. , vol.60 , pp. 173-182
    • Walsh, D.T.1    Betmouni, S.2    Perry, V.H.3
  • 74
    • 3142694174 scopus 로고    scopus 로고
    • Atypical anti-inflammatory activation of microglia induced by apoptotic neurons: Possible role of phosphatidylserine-phosphatidylserine receptor interaction
    • De Simone, R., Ajmone-Cat, M. A., Minghetti, L. (2004) Atypical anti-inflammatory activation of microglia induced by apoptotic neurons: possible role of phosphatidylserine-phosphatidylserine receptor interaction. Mol. Neurobiol. 29, 197-212.
    • (2004) Mol. Neurobiol. , vol.29 , pp. 197-212
    • De Simone, R.1    Ajmone-Cat, M.A.2    Minghetti, L.3
  • 76
    • 0033899176 scopus 로고    scopus 로고
    • Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species
    • Dringen, R., Gutterer, J. M., Hirrlinger, J. (2000) Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species. Eur. J. Biochem. 267, 4912-4916.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 4912-4916
    • Dringen, R.1    Gutterer, J.M.2    Hirrlinger, J.3
  • 77
  • 78
    • 0022969399 scopus 로고
    • Exchange of cystine and glutamate across plasma membrane of human fibroblasts
    • Bannai, S. (1986) Exchange of cystine and glutamate across plasma membrane of human fibroblasts. J. Biol. Chem. 261, 2256-2263.
    • (1986) J. Biol. Chem. , vol.261 , pp. 2256-2263
    • Bannai, S.1
  • 79
    • 0025570260 scopus 로고
    • Uptake of glutamate and cysteine in C-6 glioma cells and in cultured astrocytes
    • Cho, Y., Bannai, S. (1990) Uptake of glutamate and cysteine in C-6 glioma cells and in cultured astrocytes. J. Neurochem. 55, 2091-2097.
    • (1990) J. Neurochem. , vol.55 , pp. 2091-2097
    • Cho, Y.1    Bannai, S.2
  • 80
    • 0026637624 scopus 로고
    • A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion
    • Kato, S., Negishi, K., Mawatari, K., Kuo, C. H. (1992) A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion. Neuroscience 48, 903-914.
    • (1992) Neuroscience , vol.48 , pp. 903-914
    • Kato, S.1    Negishi, K.2    Mawatari, K.3    Kuo, C.H.4
  • 81
    • 0024210681 scopus 로고
    • A novel function of glutamine in cell culture: Utilization of glutamine for the uptake of cystine in human fibroblasts
    • Bannai, S., Ishii, T. (1988) A novel function of glutamine in cell culture: utilization of glutamine for the uptake of cystine in human fibroblasts. J. Cell. Physiol. 137, 360-366.
    • (1988) J. Cell. Physiol. , vol.137 , pp. 360-366
    • Bannai, S.1    Ishii, T.2
  • 83
    • 33746577349 scopus 로고    scopus 로고
    • Stimulation of cystine uptake by nitric oxide: Regulation of endothelial cell glutathione levels
    • Li, H., Marshall, Z. M., Whorton, A. R. (1999) Stimulation of cystine uptake by nitric oxide: regulation of endothelial cell glutathione levels. Am. J. Physiol. 276, C803-C811.
    • (1999) Am. J. Physiol. , vol.276
    • Li, H.1    Marshall, Z.M.2    Whorton, A.R.3
  • 84
    • 0033680064 scopus 로고    scopus 로고
    • Adaptive responses to peroxynitrite: Increased glutathione levels and cystine uptake in vascular cells
    • Buckley, B. J., Whorton, A. R. (2000) Adaptive responses to peroxynitrite: increased glutathione levels and cystine uptake in vascular cells. Am. J. Physiol. Cell Physiol. 279, C1168-C1176.
    • (2000) Am. J. Physiol. Cell Physiol. , vol.279
    • Buckley, B.J.1    Whorton, A.R.2
  • 85
    • 0020402139 scopus 로고
    • Adaptive enhancement of cystine and glutamate uptake in human diploid fibroblasts in culture
    • Bannai, S., Kitamura, E. (1982) Adaptive enhancement of cystine and glutamate uptake in human diploid fibroblasts in culture. Biochim. Biophys. Acta 721, 1-10.
    • (1982) Biochim. Biophys. Acta , vol.721 , pp. 1-10
    • Bannai, S.1    Kitamura, E.2
  • 86
    • 0019971177 scopus 로고
    • Transport of cystine and cysteine and cell growth in cultured human diploid fibroblasts: Effect of glutamate and homocysteate
    • Bannai, S., Ishii, T. (1982) Transport of cystine and cysteine and cell growth in cultured human diploid fibroblasts: effect of glutamate and homocysteate. J. Cell. Physiol. 112, 265-272.
    • (1982) J. Cell. Physiol. , vol.112 , pp. 265-272
    • Bannai, S.1    Ishii, T.2
  • 87
    • 0033822531 scopus 로고    scopus 로고
    • Gliotoxic action of glutamate on cultured astrocytes
    • Chen, C. J., Liao, S. L., Kuo, J. S. (2000) Gliotoxic action of glutamate on cultured astrocytes. J. Neurochem. 75, 1557-1565.
    • (2000) J. Neurochem. , vol.75 , pp. 1557-1565
    • Chen, C.J.1    Liao, S.L.2    Kuo, J.S.3
  • 88
    • 0030927533 scopus 로고    scopus 로고
    • Role of glutathione metabolism in the glutamate-induced programmed cell death of neuronal-like PC12 cells
    • Froissard, P., Monrocq, H., Duval, D. (1997) Role of glutathione metabolism in the glutamate-induced programmed cell death of neuronal-like PC12 cells. Eur. J. Pharmacol. 326, 93-99.
    • (1997) Eur. J. Pharmacol. , vol.326 , pp. 93-99
    • Froissard, P.1    Monrocq, H.2    Duval, D.3
  • 89
    • 0030707678 scopus 로고    scopus 로고
    • Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants
    • Han, D., Sen, C. K., Roy, S., Kobayashi, M. S., Tritschler, H. J., Packer, L. (1997) Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants. Am. J. Physiol. 273, R1771-R1778.
    • (1997) Am. J. Physiol. , vol.273
    • Han, D.1    Sen, C.K.2    Roy, S.3    Kobayashi, M.S.4    Tritschler, H.J.5    Packer, L.6
  • 90
    • 6744248662 scopus 로고    scopus 로고
    • The Na+-dependent glutamate and aspartate transporter supports glutathione maintenance and survival of CHO-K1 cells
    • Igo Jr., R. P., Ash, J. F. (1998) The Na+-dependent glutamate and aspartate transporter supports glutathione maintenance and survival of CHO-K1 cells. Somat. Cell Mol. Genet. 24, 341-352.
    • (1998) Somat. Cell Mol. Genet. , vol.24 , pp. 341-352
    • Igo Jr., R.P.1    Ash, J.F.2
  • 91
    • 0029844831 scopus 로고    scopus 로고
    • The role of monoamine metabolism in oxidative glutamate toxicity
    • Maher, P., Davis, J. B. (1996) The role of monoamine metabolism in oxidative glutamate toxicity. J. Neurosci. 16, 6394-6401.
    • (1996) J. Neurosci. , vol.16 , pp. 6394-6401
    • Maher, P.1    Davis, J.B.2
  • 92
    • 0024678458 scopus 로고
    • Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress
    • Murphy, T. H., Miyamoto, M., Sastre, A., Schnaar, R. L., Coyle, J. T. (1989) Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2, 1547-1558.
    • (1989) Neuron , vol.2 , pp. 1547-1558
    • Murphy, T.H.1    Miyamoto, M.2    Sastre, A.3    Schnaar, R.L.4    Coyle, J.T.5
  • 93
    • 0035478598 scopus 로고    scopus 로고
    • Oxidative glutamate toxicity can be a component of the excitotoxicity cascade
    • Schubert, D., Piasecki, D. (2001) Oxidative glutamate toxicity can be a component of the excitotoxicity cascade. J. Neurosci. 21, 7455-7462.
    • (2001) J. Neurosci. , vol.21 , pp. 7455-7462
    • Schubert, D.1    Piasecki, D.2
  • 94
    • 0030973631 scopus 로고    scopus 로고
    • The glutathione level of retinal Muller glial cells is dependent on the high-affinity sodium-dependent uptake of glutamate
    • Reichelt, W., Stabel-Burow, J., Pannicke, T., Weichert, H., Heinemann, U. (1997) The glutathione level of retinal Muller glial cells is dependent on the high-affinity sodium-dependent uptake of glutamate. Neuroscience 77, 1213-1224.
    • (1997) Neuroscience , vol.77 , pp. 1213-1224
    • Reichelt, W.1    Stabel-Burow, J.2    Pannicke, T.3    Weichert, H.4    Heinemann, U.5
  • 95
    • 0029891464 scopus 로고    scopus 로고
    • Interaction of L-cysteine with a human excitatory amino acid transporter
    • Zerangue, N., Kavanaugh, M. P. (1996) Interaction of L-cysteine with a human excitatory amino acid transporter. J. Physiol. 493, 419-423.
    • (1996) J. Physiol. , vol.493 , pp. 419-423
    • Zerangue, N.1    Kavanaugh, M.P.2
  • 96
    • 0034256935 scopus 로고    scopus 로고
    • Characterization of cystine uptake in cultured astrocytes
    • Bender, A. S., Reichelt, W., Norenberg, M. D. (2000) Characterization of cystine uptake in cultured astrocytes. Neurochem. Int. 37, 269-276.
    • (2000) Neurochem. Int. , vol.37 , pp. 269-276
    • Bender, A.S.1    Reichelt, W.2    Norenberg, M.D.3
  • 97
    • 0035206385 scopus 로고    scopus 로고
    • Molecular mechanisms of cystine transport
    • McBean, G. J., Flynn, J. (2001) Molecular mechanisms of cystine transport. Biochem. Soc. Trans. 29, 717-722.
    • (2001) Biochem. Soc. Trans. , vol.29 , pp. 717-722
    • McBean, G.J.1    Flynn, J.2
  • 98
    • 0033982706 scopus 로고    scopus 로고
    • Kinetic and pharmacological analysis of L-[35S]cystine transport into rat brain synaptosomes
    • Flynn, J., McBean, G. J. (2000) Kinetic and pharmacological analysis of L-[35S]cystine transport into rat brain synaptosomes. Neurochem. Int. 36, 513-521.
    • (2000) Neurochem. Int. , vol.36 , pp. 513-521
    • Flynn, J.1    McBean, G.J.2
  • 99
    • 18144388980 scopus 로고    scopus 로고
    • Transport of L-[14C]cystine and L-[14C]cysteine by subtypes of high affinity glutamate transporters over-expressed in HEK cells
    • Hayes, D., Wiessner, M., Rauen, T., McBean, G. J. (2005) Transport of L-[14C]cystine and L-[14C]cysteine by subtypes of high affinity glutamate transporters over-expressed in HEK cells. Neurochem. Int. 46, 585-594.
    • (2005) Neurochem. Int. , vol.46 , pp. 585-594
    • Hayes, D.1    Wiessner, M.2    Rauen, T.3    McBean, G.J.4
  • 100
    • 29444459269 scopus 로고    scopus 로고
    • Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse
    • Aoyama, K., Suh, S. W., Hamby, A. M., Liu, J., Chan, W. Y., Chen, Y., Swanson, R. A. (2006) Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse. Nat. Neurosci. 9, 119-126.
    • (2006) Nat. Neurosci. , vol.9 , pp. 119-126
    • Aoyama, K.1    Suh, S.W.2    Hamby, A.M.3    Liu, J.4    Chan, W.Y.5    Chen, Y.6    Swanson, R.A.7
  • 101
    • 0033534361 scopus 로고    scopus 로고
    • N-acetylcysteine, but not methionine or 2-oxothiazolidine-4-carboxylate, serves as cysteine donor for the synthesis of glutathione in cultured neurons derived from embryonal rat brain
    • Dringen, R., Hamprecht, B. (1999) N-acetylcysteine, but not methionine or 2-oxothiazolidine-4-carboxylate, serves as cysteine donor for the synthesis of glutathione in cultured neurons derived from embryonal rat brain. Neurosci. Lett. 259, 79-82.
    • (1999) Neurosci. Lett. , vol.259 , pp. 79-82
    • Dringen, R.1    Hamprecht, B.2
  • 102
    • 0035577287 scopus 로고    scopus 로고
    • Aminopeptidase N mediates the utilization of the GSH precursor CysGly by cultured neurons
    • Dringen, R., Gutterer, J. M., Gros, C., Hirrlinger, J. (2001) Aminopeptidase N mediates the utilization of the GSH precursor CysGly by cultured neurons. J. Neurosci. Res. 66, 1003-1008.
    • (2001) J. Neurosci. Res. , vol.66 , pp. 1003-1008
    • Dringen, R.1    Gutterer, J.M.2    Gros, C.3    Hirrlinger, J.4
  • 103
    • 0035856880 scopus 로고    scopus 로고
    • Na+ dependent glutamate transporters (EAAT1, EAAT2, and EAAT3) in primary astrocyte cultures: Effect of oxidative stress
    • Miralles, V. J., Martinez-Lopez, I., Zaragoza, R., Borras, E., Garcia, C., Pallardo, F. V., Vina, J. R. (2001) Na+ dependent glutamate transporters (EAAT1, EAAT2, and EAAT3) in primary astrocyte cultures: effect of oxidative stress. Brain Res. 922, 21-29.
    • (2001) Brain Res. , vol.922 , pp. 21-29
    • Miralles, V.J.1    Martinez-Lopez, I.2    Zaragoza, R.3    Borras, E.4    Garcia, C.5    Pallardo, F.V.6    Vina, J.R.7
  • 104
    • 0032033864 scopus 로고    scopus 로고
    • Free radicals and glutamate uptake in the retina
    • Muller, A., Maurin, L., Bonne, C. (1998) Free radicals and glutamate uptake in the retina. Gen. Pharmacol. 30, 315-318.
    • (1998) Gen. Pharmacol. , vol.30 , pp. 315-318
    • Muller, A.1    Maurin, L.2    Bonne, C.3
  • 105
    • 0035108931 scopus 로고    scopus 로고
    • Effects of L-glutamate, D-aspartate, and monensin on glycolytic and oxidative glucose metabolism in mouse astrocyte cultures: Further evidence that glutamate uptake is metabolically driven by oxidative metabolism
    • Peng, L., Swanson, R. A., Hertz, L. (2001) Effects of L-glutamate, D-aspartate, and monensin on glycolytic and oxidative glucose metabolism in mouse astrocyte cultures: further evidence that glutamate uptake is metabolically driven by oxidative metabolism. Neurochem. Int. 38, 437-443.
    • (2001) Neurochem. Int. , vol.38 , pp. 437-443
    • Peng, L.1    Swanson, R.A.2    Hertz, L.3
  • 107
    • 9444252293 scopus 로고    scopus 로고
    • Increased internalization and degradation of GLT-1 glial glutamate transporter in a cell model for familial amyotrophic lateral sclerosis (ALS)
    • Vanoni, C., Massari, S., Losa, M., Carrega, P., Perego, C., Conforti, L., Pietrini, G. (2004) Increased internalization and degradation of GLT-1 glial glutamate transporter in a cell model for familial amyotrophic lateral sclerosis (ALS). J. Cell Sci. 117, 5417-5426.
    • (2004) J. Cell Sci. , vol.117 , pp. 5417-5426
    • Vanoni, C.1    Massari, S.2    Losa, M.3    Carrega, P.4    Perego, C.5    Conforti, L.6    Pietrini, G.7
  • 110
    • 0031029223 scopus 로고    scopus 로고
    • Elevated glutamate in the cerebrospinal fluid of patients with HIV dementia
    • Ferrarese, C., Riva, R., Dolara, A., De Micheli, A., Frattola, L. (1997) Elevated glutamate in the cerebrospinal fluid of patients with HIV dementia. JAMA 277, 630.
    • (1997) JAMA , vol.277 , pp. 630
    • Ferrarese, C.1    Riva, R.2    Dolara, A.3    De Micheli, A.4    Frattola, L.5
  • 111
    • 1042289648 scopus 로고    scopus 로고
    • Up-regulation of glutamate concentration in the putamen and in the prefrontal cortex of asymptomatic SIVmac251-infected macaques without major brain involvement
    • Bossuet, C., Vaufrey, F., Conde, F., Chretien, F., Pichon, J., Hantraye, P., Le Grand, R., Dormont, D., Gras, G. (2004) Up-regulation of glutamate concentration in the putamen and in the prefrontal cortex of asymptomatic SIVmac251-infected macaques without major brain involvement. J. Neurochem. 88, 928-938.
    • (2004) J. Neurochem. , vol.88 , pp. 928-938
    • Bossuet, C.1    Vaufrey, F.2    Conde, F.3    Chretien, F.4    Pichon, J.5    Hantraye, P.6    Le Grand, R.7    Dormont, D.8    Gras, G.9
  • 113
    • 0028847323 scopus 로고
    • The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid
    • Dreyer, E. B., Lipton, S. A. (1995) The coat protein gp120 of HIV-1 inhibits astrocyte uptake of excitatory amino acids via macrophage arachidonic acid. Eur. J. Neurosci. 7, 2502-2507.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 2502-2507
    • Dreyer, E.B.1    Lipton, S.A.2
  • 114
    • 0029943301 scopus 로고    scopus 로고
    • Tumor necrosis factor α inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia
    • Fine, S. M., Angel, R. A., Perry, S. W., Epstein, L. G., Rothstein, J. D., Dewhurst, S., Gelbard, H. A. (1996) Tumor necrosis factor α inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia. J. Biol. Chem. 271, 15303-15306.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15303-15306
    • Fine, S.M.1    Angel, R.A.2    Perry, S.W.3    Epstein, L.G.4    Rothstein, J.D.5    Dewhurst, S.6    Gelbard, H.A.7
  • 115
    • 0032505644 scopus 로고    scopus 로고
    • Impairment of excitatory amino acid transport in astroglial cells infected with the human immunodeficiency virus type 1
    • Kort, J. J. (1998) Impairment of excitatory amino acid transport in astroglial cells infected with the human immunodeficiency virus type 1. AIDS Res. Hum. Retroviruses 14, 1329-1339.
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , pp. 1329-1339
    • Kort, J.J.1
  • 116
    • 0033826013 scopus 로고    scopus 로고
    • Gp120-induced alterations of human astrocyte function: Na(+)/H(+) exchange, K(+) conductance, and glutamate flux
    • Patton, H. K., Zhou, Z. H., Bubien, J. K., Benveniste, E. N., Benos, D. J. (2000) gp120-induced alterations of human astrocyte function: Na(+)/H(+) exchange, K(+) conductance, and glutamate flux. Am. J. Physiol. Cell Physiol. 279, C700-C708.
    • (2000) Am. J. Physiol. Cell Physiol. , vol.279
    • Patton, H.K.1    Zhou, Z.H.2    Bubien, J.K.3    Benveniste, E.N.4    Benos, D.J.5
  • 117
    • 0030818670 scopus 로고    scopus 로고
    • HIV-1 gp120 glycoprotein affects the astrocyte control of extracellular glutamate by both inhibiting the uptake and stimulating the release of the amino acid
    • Vesce, S., Bezzi, P., Rossi, D., Meldolesi, J., Volterra, A. (1997) HIV-1 gp120 glycoprotein affects the astrocyte control of extracellular glutamate by both inhibiting the uptake and stimulating the release of the amino acid. FEBS Lett, 411, 107-109.
    • (1997) FEBS Lett , vol.411 , pp. 107-109
    • Vesce, S.1    Bezzi, P.2    Rossi, D.3    Meldolesi, J.4    Volterra, A.5
  • 118
    • 8744257812 scopus 로고    scopus 로고
    • Endothelins negatively regulate glial glutamate transporter expression
    • Rozyczka, J., Figiel, M., Engele, J. (2004) Endothelins negatively regulate glial glutamate transporter expression. Brain Pathol. 14, 406-414.
    • (2004) Brain Pathol. , vol.14 , pp. 406-414
    • Rozyczka, J.1    Figiel, M.2    Engele, J.3
  • 119
    • 14844316278 scopus 로고    scopus 로고
    • Positive and negative regulation of EAAT2 by NF-κB: A role for N-myc in TNFα-controlled repression
    • Sitcheran, R., Gupta, P., Fisher, P. B., Baldwin, A. S. (2005) Positive and negative regulation of EAAT2 by NF-κB: a role for N-myc in TNFα-controlled repression. EMBO J. 24, 510-520.
    • (2005) EMBO J. , vol.24 , pp. 510-520
    • Sitcheran, R.1    Gupta, P.2    Fisher, P.B.3    Baldwin, A.S.4
  • 120
    • 21044434245 scopus 로고    scopus 로고
    • Modulation of Na(+)-dependent glutamate transporter of murine astrocytes by inflammatory mediators
    • Okada, K., Yamashita, U., Tsuji, S. (2005) Modulation of Na(+)-dependent glutamate transporter of murine astrocytes by inflammatory mediators. J. UOEH 27, 161-170.
    • (2005) J. UOEH , vol.27 , pp. 161-170
    • Okada, K.1    Yamashita, U.2    Tsuji, S.3
  • 121
    • 20444389341 scopus 로고    scopus 로고
    • Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1
    • Kang, D. C., Su, Z. Z., Sarkar, D., Emdad, L., Volsky, D. J., Fisher, P. B. (2005) Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1. Gene 353, 8-15.
    • (2005) Gene , vol.353 , pp. 8-15
    • Kang, D.C.1    Su, Z.Z.2    Sarkar, D.3    Emdad, L.4    Volsky, D.J.5    Fisher, P.B.6
  • 122
    • 33645871603 scopus 로고    scopus 로고
    • Corticosterone inhibits expression of the microglial glutamate transporter GLT-1 in vitro
    • Jacobsson, J., Persson, M., Hansson, E., Ronnback, L. (2006) Corticosterone inhibits expression of the microglial glutamate transporter GLT-1 in vitro. Neuroscience 139, 475-483.
    • (2006) Neuroscience , vol.139 , pp. 475-483
    • Jacobsson, J.1    Persson, M.2    Hansson, E.3    Ronnback, L.4
  • 123
    • 20144381062 scopus 로고    scopus 로고
    • Lipopolysaccharide increases microglial GLT-1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF-α
    • Persson, M., Brantefjord, M., Hansson, E., Ronnback, L. (2005) Lipopolysaccharide increases microglial GLT-1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF-α. Glia 51, 111-120.
    • (2005) Glia , vol.51 , pp. 111-120
    • Persson, M.1    Brantefjord, M.2    Hansson, E.3    Ronnback, L.4
  • 124
    • 0034726019 scopus 로고    scopus 로고
    • Protective effect of microglial conditioning medium on neuronal damage induced by glutamate
    • Watanabe, H., Abe, H., Takeuchi, S., Tanaka, R. (2000) Protective effect of microglial conditioning medium on neuronal damage induced by glutamate. Neurosci. Lett. 289, 53-56.
    • (2000) Neurosci. Lett. , vol.289 , pp. 53-56
    • Watanabe, H.1    Abe, H.2    Takeuchi, S.3    Tanaka, R.4
  • 125
    • 14844309321 scopus 로고    scopus 로고
    • Protective autoimmunity: Interferon-γ enables microglia to remove glutamate without evoking inflammatory mediators
    • Shaked, I., Tchoresh, D., Gersner, R., Meiri, G., Mordechai, S., Xiao, X., Hart, R. P., Schwartz, M. (2005) Protective autoimmunity: interferon-γ enables microglia to remove glutamate without evoking inflammatory mediators. J. Neurochem. 92, 997-1009.
    • (2005) J. Neurochem. , vol.92 , pp. 997-1009
    • Shaked, I.1    Tchoresh, D.2    Gersner, R.3    Meiri, G.4    Mordechai, S.5    Xiao, X.6    Hart, R.P.7    Schwartz, M.8
  • 126
    • 0037449150 scopus 로고    scopus 로고
    • Effects of glucocorticoids in the gp120-induced inhibition of glutamate uptake in hippocampal cultures
    • Brooke, S. M., Sapolsky, R. M. (2003) Effects of glucocorticoids in the gp120-induced inhibition of glutamate uptake in hippocampal cultures. Brain Res. 972, 137-141.
    • (2003) Brain Res. , vol.972 , pp. 137-141
    • Brooke, S.M.1    Sapolsky, R.M.2
  • 127
    • 0037452698 scopus 로고    scopus 로고
    • Insights into glutamate transport regulation in human astrocytes: Cloning of the promoter for excitatory amino acid transporter 2 (EAAT2)
    • Su, Z. Z., Leszczyniecka, M., Kang, D. C., Sarkar, D., Chao, W., Volsky, D. J., Fisher, P. B. (2003) Insights into glutamate transport regulation in human astrocytes: cloning of the promoter for excitatory amino acid transporter 2 (EAAT2). Proc. Natl. Acad. Sci. USA 100, 1955-1960.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1955-1960
    • Su, Z.Z.1    Leszczyniecka, M.2    Kang, D.C.3    Sarkar, D.4    Chao, W.5    Volsky, D.J.6    Fisher, P.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.