Inhibition of the function of trpv1-expressing nociceptive sensory neu rons by somatostatin 4 receptor agonism: Mechanism and therapeutica implications

Current Topics in Medicinal Chemistry

Volumn 11, Issue 17, 2011, Pages 2253-2263

  Szolcsányi, János ^a   Pintér, Erika ^a   Helyes, Zsuzsanna ^a   Petho, Gábor ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Antiinflammatory effect; Antinociception; Capsaicin; Sensocrine effect; Somatostatin; Trpa1; Trpv1

Indexed keywords

ANALGESIC AGENT; ANTIINFLAMMATORY AGENT; CORTISTATIN; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLLYSYLCYSTEINYLTHREONINAMIDE 2,6 DISULFIDE; DICLOFENAC; J 2156; L 803087; MELOXICAM; MERCAPTAMINE; OCTREOTIDE; SOMATOSTATIN; SOMATOSTATIN ANTIBODY; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR 1; SOMATOSTATIN RECEPTOR 4; SOMATOSTATIN RECEPTOR 4 AGONIST; TT 250; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1;

ALLODYNIA; ANALGESIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; DORSAL ROOT; DRUG EFFECT; DRUG TARGETING; GENE DELETION; GENE EXPRESSION; GUINEA PIG; HUMAN; HYPERALGESIA; IMMUNOREACTIVITY; IN VITRO STUDY; INFLAMMATION; KNOCKOUT MOUSE; NEUROPATHY; NOCICEPTION; NONHUMAN; RECEPTOR BLOCKING; REGULATORY MECHANISM; REVIEW; SEIZURE; SENSORY NERVE CELL; SOMATOSTATIN RELEASE; TRACHEA;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; HUMANS; RECEPTORS, SOMATOSTATIN; SENSORY RECEPTOR CELLS; STRUCTURE-ACTIVITY RELATIONSHIP; TRPV CATION CHANNELS;

EID: 80052235371     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/156802611796904852     Document Type: Review

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