Nonpeptide somatostatin agonists with sst4 selectivity: Synthesis and structure-activity relationships of thioureas

Journal of Medicinal Chemistry

Volumn 41, Issue 24, 1998, Pages 4693-4705

  Liu, Shenquan ^a   Tang, Cheng ^a   Ho, Bin ^a   Ankersen, Michael ^b   Stidsen, Carsten E ^b   Crider, A Michael ^a  

^a UNIVERSITY OF LOUISIANA AT MONROE   (United States)

^b NOVO NORDISK A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

1 [3 [N (5 BROMO 2 PYRIDYL) N (3,4 DICHLOROBENZYL)AMINO]PROPYL] 3 [3 (4 IMIDAZOLYL)PROPYL]THIOUREA; 3 [3 (1H IMIDAZOL 4 YL)PROPYL] 1 [2 [N (5 BROMOPYRID 2 YL) N (3,4 DICHLOROBENZYL)AMINO]ETHYL]UREA; 3 [3 (1H IMIDAZOL 4 YL)PROPYL] 1 [3 [N (5 BROMOPYRID 2 YL) N (NAPHTH 1 YLMETHYL)AMINO]PROPYL]THIOUREA; CYCLIC AMP; FORSKOLIN; ISOBUTYLMETHYLXANTHINE; LYSINE; PHENYLALANINE; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR; THIOUREA DERIVATIVE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG SELECTIVITY; DRUG SYNTHESIS; GLAUCOMA; HUMAN; HUMAN CELL; NONHUMAN; STRUCTURE ACTIVITY RELATION;

AMINOPYRIDINES; ANIMALS; CELL LINE; CRICETINAE; GLAUCOMA; HUMANS; MEMBRANE PROTEINS; RADIOLIGAND ASSAY; RECEPTORS, SOMATOSTATIN; SOMATOSTATIN; STRUCTURE-ACTIVITY RELATIONSHIP; THIOUREA;

EID: 0032548003     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980118e     Document Type: Article

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