Identification and pharmacological characterization of somatostatin receptors in rat lung

British Journal of Pharmacology

Volumn 121, Issue 5, 1997, Pages 963-971

  Schloos, Jürgen ^a,b   Raulf, Friedrich ^a   Hoyer, Daniel ^a   Bruns, Christian ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b BEIERSDORF AG   (Germany)

Author keywords

Rat lung; Somatostatin; Somatostatin receptors; SRIF analogues; sst4 receptor subtype

Indexed keywords

ANGIOPEPTIN; CGP 23996; DEXTRO PHENYLALANYLPHENYLALANYLTYROSYL DEXTRO TRYPTOPHYLLYSYLVALYLPHENYLALANYL DEXTRO [3 (2 NAPHTHYL)ALANINAMIDE]; MEMBRANE PROTEIN; MESSENGER RNA; OCTREOTIDE; SEGLITIDE; SOMATOSTATIN DERIVATIVE; SOMATOSTATIN RECEPTOR; VAPREOTIDE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; CELL MEMBRANE; CHO CELL; CONTROLLED STUDY; DISSOCIATION CONSTANT; HALF LIFE TIME; LIGAND BINDING; LUNG PARENCHYMA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR DENSITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; AUTORADIOGRAPHY; CELL MEMBRANE; CHO CELLS; CRICETINAE; HUMANS; LUNG; MALE; MEMBRANES; POLYMERASE CHAIN REACTION; PROTEINS; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SOMATOSTATIN; RNA, MESSENGER;

EID: 0031008488     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701205     Document Type: Article

References (48)

1. BALAGUER, L., ROMANO, J. & RUIZ PESINI, P. (1992). Localization of serotonin, cholecystokinin and somatostatin immunoreactivity in the lower respiratory tract of embryonic, foetal and postnatal sheep. Histol. Histopathol., 7, 703-708.
2. BARRIOS, V., FERNANDEZ IRIARTE, M.C., MORCILLO, E., PRIETO, J.C. & ARILLA, E. (1987). Effect of sensitization on somatostatin concentration and binding in cytosol from guinea pig airways. Reg. Peptides, 19, 161-168.
3. BELL, G.I. & REISINE, T. (1993). Molecular biology of somatostatin receptors. Trends Neurosci., 16, 34-38.
4. BRADFORD, M. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
5. BRAZEAU, P., VALE, W., BURGUS, R., LING, N., BUTCHER, M., RIVIER, J. & GUILLEMIN, R. (1973). Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormones. Science, 179, 77-79.
6. BRUNO, J.F., XU, Y., SONG, J. & BERELOWITZ, M. (1993). Tissue distribution of somatostatin receptor subtype messenger ribonucleic acid in the rat. Endocrinology, 133, 2561-2567.
7. BRUNS, C., DIETL, M.M., PALACIOS, J.M. & PLESS, J. (1990). Identification and characterization of somatostatin receptors in neonatal rat long bones. Biochem. J., 265, 39-44.
8. BRUNS, C., RAULF, F., HOYER, D., SCHLOOS, J., LÜBBERT, H. & WECKBECKER, G. (1996). Binding properties of somatostatin receptor subtypes. Metabolism, 45, 17-20.
9. BRUNS, C., WECKBECKER, G., RAULF, F., KAUPMANN, K., SCHOEFFTER, P., HOYER, D. & LUEBBERT, H. (1994). Molecular pharmacology of somatostatin receptor subtypes. Ann. N. Y. Acad. Sci., 733, 138-146.
10. BRUNS, C., WECKBECKER, G., RAULF, F., LUEBBERT, H.P. & HOYER, D. (1995). Characterization of somatostatin receptor subtypes. Ciba Foundation Symposium, 190, 89-101.
11. -) cells. Br. J. Pharmacol., 117, 639-646.
12. DAYER, A.M., DE MEY, J. & WILL, J.A. (1985). Localization of somatostatin-, bombesin-, and serotonin-like immunoreactivity in the lung of the fetal Rhesus monkey. Cell Tissue Res., 239, 621-625.
13. EPELBAUM, J. (1986). Somatostatin in the central nervous system: physiology and pathological modifications. Prog. Neurobiol., 27, 63-100.
14. GHATEI, M.A., SHEPPARD, N., O'SHAUGNESSY, D.J., ADRIAN, T.E., MCGREGOR, G.P., POLAK, J.M. & BLOOM, S.R. (1982). Regulatory peptides in the mammalian respiratory tract. Endocrinology, 111, 1248-1254.
15. HOYER, D., BELL, G.I . BERELOWITZ, M., EPELBAUM, J., FENIUK, W., HUMPHREY, P.P.A., O'CARROLL, A.M., PATEL, Y.C., SCHONBRUNN, A., TAYLOR, J.E. & REISINE, T. (1995). Classification and nomenclature of somatostatin receptors. Trends Pharmacol. Sci., 16, 86-88.
16. 131I-labelled human growth hormone of high specific radioactivity. Biochem. J., 89, 114-123.
17. KAUPMANN, K., BRUNS, C., HOYER, D., SEUWEN, K. & LÜBBERT, H. (1993). Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain. FEBS Lett., 331, 53-59.
18. KLUXEN, F.W., BRUNS, C. & LÜBBERT, H. (1992). Expression cloning of a rat brain somatostatin receptor cDNA. Proc. Natl. Acad. Sci. U.S.A., 89, 4618-4622.
19. KROWKA, M.J., DICKSON, E.R. & CORTESE, D.A. (1993). Hepatopulmonary syndrome. Clinical observations and lack of therapeutic response to somatostatin analogue. Chest, 104, 515-521.
20. O'CARROLL, A.M., LOLAIT, S.J., KONIG, M. & MAHAN, L.C. (1992). Molecular cloning and expression of a pituitary somatostatin receptor with preferential affinity for somatostatin-28. Mol. Pharmacol., 42, 939-946.
21. PATEL, Y.C., GREENWOOD, M.T., WARSZYNSKA, A., PANETTA, R. & SRIKANT, C.B. (1994a). All five cloned human somatostatin receptors (hSSTR1-5) are functionally coupled to adenylyl cyclase. Biochem. Biophys. Res. Commun., 198, 605-612.
22. PATEL, Y.C., PANETTA, R., ESCHER, E., GREENWOOD, M. & SRIKANT, C.B. (1994b). Expression of multiple somatostatin receptor genes in AtT-20 cells. Evidence for a novel somatostatin-28 selective receptor subtype. J. Biol. Chem., 269, 1506-1509.
23. PERKS, A.M., KWOK, Y.N., MCINTOSH, C.H., RUIZ, T. & KINDLER, P.M. (1992). Changes in somatostatin-like immunoreactivity in lungs from perinatal guinea pigs and the effects of somatostatin-14 on lung liquid production. J. Dev. Physiol., 18, 151-159.
24. PERKS, A.M. & CASSIN, S. (1987). Hormonal influences on fetal and perinatal water metabolism. In Endocrinology and Physiology of Reproduction. ed. Leung, P.C.K., Armstrong, D.T., Ruf, K.B., Moger, W.H. & Friesen, H.G. pp. 303-330. New York: Plenum Publisher Co.
25. RAYNOR, K., MURPHY, W.A., COY, D.H., TAYLOR, J.E., MOREAU, J.P., YASUDA, K., BELL, G.I. & REISINE, T. (1993a). Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides. Mol. Pharmacol., 43, 838-844.
26. RAYNOR, K., O'CARROLL, A.M., KONG, H., YASUDA, K., MAHAN, L.C., BELL, G.I. & REISINE, T. (1993b). Characterization of cloned somatostatin receptors SSTR4 and SSTR5. Mol. Pharmacol., 44, 385-392.
27. REICHLIN, S. (1983). Somatostatin. N. Engl. J. Med., 309, 1459-1501.
28. REUBI, J., LAMBERTS, S.W.J. & MAURER, R. (1988). Somatostatin receptors in normal and tumoral tissue. Horm. Res., 29, 65-69.
29. ROHRER, L., RAULF, F., BRUNS, C., BUETTNER, R., HOFSTAEDTER, F. & SCHÜLE, R. (1993). Cloning and characterization of a fourth human somatostatin receptor. Proc. Natl. Acad. Sci. U.S.A., 90, 4196-4200.
30. RUGGERE, M.D. & PATEL, Y.C. (1985). Somatostatin metabolism by the isolated rat lung. Endocrinology, 117, 1870-1873.
31. SAKAI, A. & VOELKEL, F. (1988). Dibutyryl cyclic adenosine monophosphate inhibits pulmonary vasoconstriction. Lung, 166, 221-231.
32. SAMBROCK, J., FRITSCH, E.F. & MANIATIS, T. (1989). Molecular cloning: A Laboratory Manual. 2nd Ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
33. SCATCHARD, G. (1949). The attraction of proteins for small molecules and ions. Ann. New York Acad. Sci., 51, 660-672.
34. SCHEUERMANN, D.W., ADRIAENSEN, D., TIMMERMANS, J.P. & DE GROODT LASSEEL, M.H. (1992). Comparative histological overview of the chemical coding of the pulmonary neuroepithelial endocrine system in health and disease. Eur. J. Morphol., 30, 101-112.
35. 3H-UK-14,304: regulation by Gpp(NH)p and cations. Naunyn-Schmiedeberg's Arch. Pharmacol., 336, 48-59.
36. SCHLOOS, J., RAULF, F., HOYER, D., ENGEL, G. & BRUNS, C. (1995). Identification and characterization of somatostatin receptors expressed in rat lung tissue. Br. J. Pharmacol., 114, 49P.
37. SCHONBRUNN, A. & TASHJIAN, J.A. (1978). Characterization of functional receptors for somatostatin in rat pituitary cells in culture. J. Biol. Chem., 253, 6473-6483.
38. SEKIZAWA, K., GRAF, P.D. & NADEL, J.A. (1989). Somatostatin potentiates cholinergic neurotransmission in ferret trachea. J. Appl. Physiol., 67, 2397-2400.
39. TAMAOKI, J., TAGAYA, E., YAMAUCHI, F., CHIYOTANI, A & KONNO, K. (1994). Pertussis toxin-sensitive airway beta-adrenergic dysfunction by somatostatin. Respir. Physiol., 95, 99-108.
40. TOMIOKA, M., GOTO, T., LEE, T.D., BIENENSTOCK, J. & BEFUS, A.D. (1989). Isolation and characterization of lung mast cells from rats with bleomycin-induced pulmonary fibrosis. Immunology, 66, 439-444.
41. TRAN, V.T., BEAL, M.F. & MARTIN, J.B. (1985). Two types of somatostatin receptors differentiated by cyclic somatostatin analogs. Science, 228, 492-495.
42. WAGNER, U., FEHMANN, H.C., BREDENBRÖCKER, D., YU, F., BARTH, P.J. & VON WICHERT, P. (1995a). Galanin and somatostatin inhibition of neurokinin A and B induced airway mucus secretion in the rat. Life Sci., 57, 283-289.
43. WAGNER, U., FEHMANN, H.C. BREDENBRÖCKER, D., YU, F., BARTH, P.J. & VON WICHERT, P. (1995b). Galanin and somatostatin inhibition of substance P-induced airway mucus secretion in the rat. Neuropeptides, 28, 59-64.
44. WECKBECKER, G., RAULF, F., STOLZ, B. & BRUNS, C. (1993). Somatostatin analogs for diagnosis and treatment of cancer. Pharmacol. Ther., 60, 245-264.
45. YAMADA, T. & CHIBA, T. (1989). Somatostatin. In Handbook of Physiology, Sect 6, Vol II. ed. Marlouf, G. pp. 431-453. Bethesda, MD: American Physiological Society.
46. YAMADA, Y., POST, S.R., WANG, K., TAGER, H.S., BELL, G.I. & SEINO, S. (1992a). Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract and kidney. Proc. Natl. Acad. Sci. U.S.A., 89, 251-255.
47. YAMADA, Y., REISINE, T., LAW, S.F., IHARA, Y., KUBOTA, A., KAGIMOTO, S., SEINO, M., SEINO, Y., BELL, G.I. & SEINO, S. (1992b). Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase. Mol. Endocrinol., 6, 2136-2142.
48. YASUDA, K., RENS DOMIANO, S., BREDER, C.D., LAW, S.F., SAPER, C.B., REISINE, T. & BELL, G.I. (1992). Cloning of a novel somatostatin receptor, SSTR3, coupled to adenylylcyclase. J. Biol. Chem., 267, 20422-20428.