Abdominal surgery performed under general anesthesia increases somatostatin-like immunoreactivity in human serum

NeuroImmunoModulation

Volumn 15, Issue 3, 2008, Pages 153-156

  Antal, Andras ^a   Nemeth, Jozsef ^b   Szolcsányi, Janos ^b   Pozsgai, Gabor ^b   Pinter, Erika ^b  

^a General Hospital Nagyatad   (Hungary)

^b UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Abdominal surgery; Radioimmunoassay; Sensory nerves; Somatostatin like immunoreactivity

Indexed keywords

ATROPINE; FENTANYL; MIDAZOLAM; PETHIDINE; PROPOFOL; SOMATOSTATIN;

ABDOMINAL SURGERY; ABDOMINAL WALL HERNIA; ADULT; ANTINOCICEPTION; ARTICLE; BLOOD SAMPLING; CHOLECYSTECTOMY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENERAL ANESTHESIA; HUMAN; IMMUNOREACTIVITY; INGUINAL HERNIA; MALE; PRIORITY JOURNAL; RADIOIMMUNOASSAY;

ABDOMINAL WALL; AGED; ANESTHETICS, GENERAL; ANTI-INFLAMMATORY AGENTS; CHOLECYSTECTOMY, LAPAROSCOPIC; FEEDBACK; FEMALE; HERNIA, INGUINAL; HUMANS; MALE; MIDDLE AGED; NERVE FIBERS, UNMYELINATED; NOCICEPTORS; PAIN; RADIOIMMUNOASSAY; SENSORY RECEPTOR CELLS; SOMATOSTATIN; UP-REGULATION;

EID: 49849084321     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000151528     Document Type: Article

References (19)

1. Pintér E, Szolcsányi J: Plasma extravasation in the skin and pelvic organs evoked by antidromic stimulation of the lumbosacral dorsal roots in the rat. Neuroscience 1995;68:603-614.
2. Szolcsanyi J, Helyes Z, Oroszi G, Nemeth J, Pinter E: Release of somatostatin and its role in the mediation of the anti-inflammatory effect induced by antidromic stimulation of sensory fibres of rat sciatic nerve. Br J Pharmacol 1998;123:936-942.
3. Maggi CA: Tachykinins and calcitonin gene-related peptide as co-transmitters released from peripheral endings of sensory nerves. Prog Neurobiol 1995;45:1-98.
4. Patel YC: Somatostatin and its receptor family. Front Neuroendocrinol 1999;20:157-198.
5. Szolcsanyi J, Pinter E, Helyes Z, Oroszi G, Nemeth J: Systemic anti-inflammatory effect induced by counter-irritation through a local release of somatostatin from nociceptors. Br J Pharmacol 1998;125:916-922.
6. Green PG, Basbaum AI, Levine JD: Sensory neuropeptide interactions in the production of plasma extravasation in the rat. Neuroscience 1992;50:745-749.
7. Selmer I, Schindler M, Allen JP, Humphrey PP, Emson PC: Advances in understanding neuronal somatostatin receptors. Regul Pept 2000;90:1-18.
8. Than M, Nemeth J, Szilvassy Z, Pinter E, Helyes Z, Szolcsanyi J: Systemic anti-inflammatory effect of somatostatin released from capsaicin-sensitive vagal and sciatic sensory fibres of the rat and guinea-pig. Eur J Pharmacol 2000;399:251-258.
9. Pinter E, Helyes Z, Szolcsanyi J: Inhibitory effect of somatostatin on inflammation and nociception. Pharmacol Ther 2006;112:440-456.
10. Ten Bokum AM, Hofland LJ, van Hagen PM: Somatostatin and somatostatin receptors in the immune system: a review. Eur Cytokine Netw 2000;11:161-176.
11. Karalis K, Mastorakos G, Chrousos GP, Tolis G: Somatostatin analogues suppress the inflammatory reaction in vivo. J Clin Invest 1994;93:2000-2006.
12. Helyes Z, Pintér E, Németh J, Kéri Gy, Thán M, Oroszi G, Horváth A, Szolcsányi J: Anti-inflammatory effect of synthetic somatostatin analogues in the rat. Br J Pharmacol 2001;134:1571-1579.
13. Pinter E, Helyes Z, Nemeth J, Porszasz R, Petho G, Than M, Keri G, Horvath A, Jakab B, Szolcsanyi J: Pharmacological characterisation of the somatostatin analogue TT-232: effects on neurogenic and non-neurogenic inflammation and neuropathic hyperalgesia. Naunyn Schmiedebergs Arch Pharmacol 2002;366:142-150.
14. Németh J, Helyes Z, Görcs T, Gardi J, Pintér E, Szolcsányi J: Development of somatostatin radioimmunoassay for the measurement of plasma and tissue contents of hormone. Acta Physiol Hung 1996;84:313-315.
15. Tsuda K, Sakurai H, Seino Y, Seino S, Tanigawa K, Kuzuya H, Imura H: Somatostatin-like immunoreactivity in human peripheral plasma measured by radioimmunoassay following affinity chromatography. Diabetes 1981;30:471-474.
16. Helyes Z, Pinter E, Nemeth J, Szolcsanyi J: Pharmacological targets for the inhibition of neurogenic inflammation. Curr Med Chem Anti-Inflammatory Anti-Allergy Agents 2003;2:191-218.
17. Robinson TN, Stiegmann GV: Minimal invasive surgery. Endoscopy 2004;36:48-51.
18. Demchyshyn LL, Srikant CB, Sunahara RK, Kent G, Seeman P, Van Tol HH, Panetta R, Patel YC, Niznik HB: Cloning and expression of human somatostatin -14-selective receptor variant (somatostatin receptor 4) located on chromosome 20. Mol Pharmacol 1993;43:894-901.
19. Yamada Y, Kagimoto S, Kubota A, Yasuda K, Masuda K, Someya Y, Ihara Y, Li Q, Imura H, Seino S, Seino Y: Cloning, functional expression and pharmacological characterization of fourth (hSSTR4) and fifth (hSSTR5) human somatostatin receptor subtype. Biochem Biophys Res Commun 1993;195:844-852.