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Volumn 31, Issue 16, 2011, Pages 3457-3471

Cdc25A regulates matrix metalloprotease 1 through Foxo1 and mediates metastasis of breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

CDC25A PROTEIN; CDC25A PROTEIN ANTIBODY; CYCLIN DEPENDENT KINASE 2; INTERSTITIAL COLLAGENASE; PROTEIN ANTIBODY; PROTEIN TYROSINE PHOSPHATASE; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

EID: 79961137121     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.05523-11     Document Type: Article
Times cited : (61)

References (57)
  • 1
    • 33847026354 scopus 로고    scopus 로고
    • Autophagy delays apoptotic death in breast cancer cells following DNA damage
    • Abedin, M. J., D. Wang, M. A. McDonnell, U. Lehmann, and A. Kelekar. 2007. Autophagy delays apoptotic death in breast cancer cells following DNA damage. Cell Death Differ. 14:500-510.
    • (2007) Cell Death Differ , vol.14 , pp. 500-510
    • Abedin, M.J.1    Wang, D.2    McDonnell, M.A.3    Lehmann, U.4    Kelekar, A.5
  • 2
    • 33846294435 scopus 로고    scopus 로고
    • FoxOs in tumor suppression and stem cell maintenance
    • Arden, K. C. 2007. FoxOs in tumor suppression and stem cell maintenance. Cell 128:235-237.
    • (2007) Cell , vol.128 , pp. 235-237
    • Arden, K.C.1
  • 3
    • 41849101660 scopus 로고    scopus 로고
    • Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NFkappaB
    • Bachmeier, B. E., et al. 2008. Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NFkappaB. Carcinogenesis 29:779-789.
    • (2008) Carcinogenesis , vol.29 , pp. 779-789
    • Bachmeier, B.E.1
  • 4
    • 0032766844 scopus 로고    scopus 로고
    • Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin Eand cyclin A-dependent kinases
    • Blomberg, I., and I. Hoffmann. 1999. Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin Eand cyclin A-dependent kinases. Mol. Cell. Biol. 19:6183-6194.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 6183-6194
    • Blomberg, I.1    Hoffmann, I.2
  • 5
    • 34250865564 scopus 로고    scopus 로고
    • CDC25 phosphatases in cancer cells: key players? Good targets?
    • Boutros, R., V. Lobjois, and B. Ducommun. 2007. CDC25 phosphatases in cancer cells: key players? Good targets? Nat. Rev. Cancer 7:495-507.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 495-507
    • Boutros, R.1    Lobjois, V.2    Ducommun, B.3
  • 6
    • 65549158779 scopus 로고    scopus 로고
    • Matrix metalloproteinase 1.3 and 12 polymorphisms and esophageal adenocarcinoma risk and prognosis
    • Bradbury, P. A., et al. 2009. Matrix metalloproteinase 1, 3 and 12 polymorphisms and esophageal adenocarcinoma risk and prognosis. Carcinogenesis 30:793-798.
    • (2009) Carcinogenesis , vol.30 , pp. 793-798
    • Bradbury, P.A.1
  • 7
    • 0242497228 scopus 로고    scopus 로고
    • Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage
    • Busino, L., et al. 2003. Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage. Nature 426:87-91.
    • (2003) Nature , vol.426 , pp. 87-91
    • Busino, L.1
  • 8
    • 0033796031 scopus 로고    scopus 로고
    • Role of the Cdc25A phosphatase in human breast cancer
    • Cangi, M. G., et al. 2000. Role of the Cdc25A phosphatase in human breast cancer. J. Clin. Invest. 106:753-761.
    • (2000) J. Clin. Invest. , vol.106 , pp. 753-761
    • Cangi, M.G.1
  • 9
    • 44449173164 scopus 로고    scopus 로고
    • Membrane type 1 matrix metalloproteinase induces epithelial-to-mesenchymal transition in prostate cancer
    • Cao, J., et al. 2008. Membrane type 1 matrix metalloproteinase induces epithelial-to-mesenchymal transition in prostate cancer. J. Biol. Chem. 283: 6232-6240.
    • (2008) J. Biol. Chem. , vol.283 , pp. 6232-6240
    • Cao, J.1
  • 12
    • 0142027900 scopus 로고    scopus 로고
    • Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding
    • Chen, M. S., C. E. Ryan, and H. Piwnica-Worms. 2003. Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding. Mol. Cell. Biol. 23:7488-7497.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 7488-7497
    • Chen, M.S.1    Ryan, C.E.2    Piwnica-Worms, H.3
  • 13
    • 41149165903 scopus 로고    scopus 로고
    • High MMP-1 mRNA expression is a risk factor for disease-free and overall survivals in patients with invasive breast carcinoma
    • Cheng, S., et al. 2008. High MMP-1 mRNA expression is a risk factor for disease-free and overall survivals in patients with invasive breast carcinoma. J. Surg. Res. 146:104-109.
    • (2008) J. Surg. Res. , vol.146 , pp. 104-109
    • Cheng, S.1
  • 14
    • 58149102321 scopus 로고    scopus 로고
    • Molecular basis of metastasis
    • Chiang, A. C., and J. Massague. 2008. Molecular basis of metastasis. N. Engl. J. Med. 359:2814-2823.
    • (2008) N. Engl. J. Med. , vol.359 , pp. 2814-2823
    • Chiang, A.C.1    Massague, J.2
  • 15
    • 58149085157 scopus 로고    scopus 로고
    • CDC25A functions as a novel Ar corepressor in prostate cancer cells
    • Chiu, Y. T., et al. 2009. CDC25A functions as a novel Ar corepressor in prostate cancer cells. J. Mol. Biol. 385:446-456.
    • (2009) J. Mol. Biol. , vol.385 , pp. 446-456
    • Chiu, Y.T.1
  • 16
    • 70349737813 scopus 로고    scopus 로고
    • Confounding effects in "a sixgene signature predicting breast cancer lung metastasis"
    • Culhane, A. C., and J. Quackenbush. 2009. Confounding effects in "a sixgene signature predicting breast cancer lung metastasis". Cancer Res. 69: 7480-7485.
    • (2009) Cancer Res. , vol.69 , pp. 7480-7485
    • Culhane, A.C.1    Quackenbush, J.2
  • 17
    • 0037040901 scopus 로고    scopus 로고
    • A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells
    • Dhawan, P., and A. Richmond. 2002. A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells. J. Biol. Chem. 277:7920-7928.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7920-7928
    • Dhawan, P.1    Richmond, A.2
  • 18
    • 15044365805 scopus 로고    scopus 로고
    • Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases
    • Ferguson, A. M., L. S. White, P. J. Donovan, and H. Piwnica-Worms. 2005. Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases. Mol. Cell. Biol. 25:2853-2860.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 2853-2860
    • Ferguson, A.M.1    White, L.S.2    Donovan, P.J.3    Piwnica-Worms, H.4
  • 19
    • 0026319225 scopus 로고
    • Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins
    • Galaktionov, K., and D. Beach. 1991. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins. Cell 67:1181-1194.
    • (1991) Cell , vol.67 , pp. 1181-1194
    • Galaktionov, K.1    Beach, D.2
  • 20
    • 0029119560 scopus 로고
    • CDC25 phosphatases as potential human oncogenes
    • Galaktionov, K., et al. 1995. CDC25 phosphatases as potential human oncogenes. Science 269:1575-1577.
    • (1995) Science , vol.269 , pp. 1575-1577
    • Galaktionov, K.1
  • 21
    • 0030972853 scopus 로고    scopus 로고
    • Overexpression of CDC25A and CDC25B in head and neck cancers
    • Gasparotto, D., et al. 1997. Overexpression of CDC25A and CDC25B in head and neck cancers. Cancer Res. 57:2366-2368.
    • (1997) Cancer Res , vol.57 , pp. 2366-2368
    • Gasparotto, D.1
  • 22
    • 0029789811 scopus 로고    scopus 로고
    • Long-term follow-up of patients with complete remission following combination chemotherapy for metastatic breast cancer
    • Greenberg, P. A., et al. 1996. Long-term follow-up of patients with complete remission following combination chemotherapy for metastatic breast cancer. J. Clin. Oncol. 14:2197-2205.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 2197-2205
    • Greenberg, P.A.1
  • 23
    • 33750032892 scopus 로고    scopus 로고
    • CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage
    • Huang, H., K. M. Regan, Z. Lou, J. Chen, and D. J. Tindall. 2006. CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage. Science 314:294-297.
    • (2006) Science , vol.314 , pp. 294-297
    • Huang, H.1    Regan, K.M.2    Lou, Z.3    Chen, J.4    Tindall, D.J.5
  • 24
    • 34548289502 scopus 로고    scopus 로고
    • Dynamic FoxO transcription factors
    • Huang, H., and D. J. Tindall. 2007. Dynamic FoxO transcription factors. J. Cell Sci. 120:2479-2487.
    • (2007) J. Cell Sci. , vol.120 , pp. 2479-2487
    • Huang, H.1    Tindall, D.J.2
  • 25
    • 16644385490 scopus 로고    scopus 로고
    • Expression of cdc25A and cdc25B phosphatase in breast carcinoma
    • Ito, Y., et al. 2004. Expression of cdc25A and cdc25B phosphatase in breast carcinoma. Breast Cancer 11:295-300.
    • (2004) Breast Cancer , vol.11 , pp. 295-300
    • Ito, Y.1
  • 26
    • 66949174829 scopus 로고    scopus 로고
    • The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers
    • Jeffery, N., M. H. McLean, E. M. El-Omar, and G. I. Murray. 2009. The matrix metalloproteinase/tissue inhibitor of matrix metalloproteinase profile in colorectal polyp cancers. Histopathology 54:820-828.
    • (2009) Histopathology , vol.54 , pp. 820-828
    • Jeffery, N.1    McLean, M.H.2    El-Omar, E.M.3    Murray, G.I.4
  • 27
    • 0028314952 scopus 로고
    • Cdc25A is a novel phosphatase functioning early in the cell cycle
    • Jinno, S., et al. 1994. Cdc25A is a novel phosphatase functioning early in the cell cycle. EMBO J. 13:1549-1556.
    • (1994) EMBO J. , vol.13 , pp. 1549-1556
    • Jinno, S.1
  • 28
    • 37349094929 scopus 로고    scopus 로고
    • GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers
    • Kang, T., et al. 2008. GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers. Cancer Cell 13:36-47.
    • (2008) Cancer Cell , vol.13 , pp. 36-47
    • Kang, T.1
  • 29
    • 78449252760 scopus 로고    scopus 로고
    • CDC 25A gene 263C/T, -350C/T, and -51C/G polymorphisms in breast carcinoma
    • Karagoz, I. D., et al. 2010. CDC 25A gene 263C/T, -350C/T, and -51C/G polymorphisms in breast carcinoma. Tumour Biol. 31:597-604.
    • (2010) Tumour Biol. , vol.31 , pp. 597-604
    • Karagoz, I.D.1
  • 30
    • 61849135725 scopus 로고    scopus 로고
    • A comparative review of thermography as a breast cancer screening technique
    • Kennedy, D. A., T. Lee, and D. Seely. 2009. A comparative review of thermography as a breast cancer screening technique. Integr. Cancer Ther. 8:9-16.
    • (2009) Integr. Cancer Ther. , vol.8 , pp. 9-16
    • Kennedy, D.A.1    Lee, T.2    Seely, D.3
  • 31
    • 72249093615 scopus 로고    scopus 로고
    • Tumor self-seeding by circulating cancer cells
    • Kim, M. Y., et al. 2009. Tumor self-seeding by circulating cancer cells. Cell 139:1315-1326.
    • (2009) Cell , vol.139 , pp. 1315-1326
    • Kim, M.Y.1
  • 32
    • 0030063315 scopus 로고    scopus 로고
    • Hypoxia arrests ovarian carcinoma cell cycle progression, but invasion is unaffected
    • Krtolica, A., and J. W. Ludlow. 1996. Hypoxia arrests ovarian carcinoma cell cycle progression, but invasion is unaffected. Cancer Res. 56:1168-1173.
    • (1996) Cancer Res. , vol.56 , pp. 1168-1173
    • Krtolica, A.1    Ludlow, J.W.2
  • 33
    • 34250857019 scopus 로고    scopus 로고
    • Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis
    • Langley, R. R., and I. J. Fidler. 2007. Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis. Endocr. Rev. 28:297-321.
    • (2007) Endocr. Rev. , vol.28 , pp. 297-321
    • Langley, R.R.1    Fidler, I.J.2
  • 34
    • 0036544855 scopus 로고    scopus 로고
    • Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation
    • Lincoln, A. J., et al. 2002. Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation. Nat. Genet. 30:446-449.
    • (2002) Nat. Genet. , vol.30 , pp. 446-449
    • Lincoln, A.J.1
  • 35
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma, L., J. Teruya-Feldstein, and R. A. Weinberg. 2007. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449:682-688.
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 36
    • 13444268127 scopus 로고    scopus 로고
    • Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors
    • Minn, A. J., et al. 2005. Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors. J. Clin. Invest. 115:44-55.
    • (2005) J. Clin. Invest. , vol.115 , pp. 44-55
    • Minn, A.J.1
  • 37
    • 34848881584 scopus 로고    scopus 로고
    • A review of lapatinib ditosylate in the treatment of refractory or advanced breast cancer
    • Nelson, M. H., and C. R. Dolder. 2007. A review of lapatinib ditosylate in the treatment of refractory or advanced breast cancer. Ther. Clin. Risk Manag. 3:665-673.
    • (2007) Ther. Clin. Risk Manag. , vol.3 , pp. 665-673
    • Nelson, M.H.1    Dolder, C.R.2
  • 38
    • 0033629383 scopus 로고    scopus 로고
    • Cell cycle regulation by the Cdc25 phosphatase family
    • Nilsson, I., and I. Hoffmann. 2000. Cell cycle regulation by the Cdc25 phosphatase family. Prog. Cell Cycle Res. 4:107-114.
    • (2000) Prog. Cell Cycle Res. , vol.4 , pp. 107-114
    • Nilsson, I.1    Hoffmann, I.2
  • 39
    • 62049086102 scopus 로고    scopus 로고
    • An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance
    • Ouyang, W., O. Beckett, R. A. Flavell, and M. O. Li. 2009. An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance. Immunity 30:358-371.
    • (2009) Immunity , vol.30 , pp. 358-371
    • Ouyang, W.1    Beckett, O.2    Flavell, R.A.3    Li, M.O.4
  • 40
    • 18844421896 scopus 로고    scopus 로고
    • Identification of MMP-1 as a putative breast cancer predictive marker by global gene expression analysis
    • Poola, I., et al. 2005. Identification of MMP-1 as a putative breast cancer predictive marker by global gene expression analysis. Nat. Med. 11:481-483.
    • (2005) Nat. Med. , vol.11 , pp. 481-483
    • Poola, I.1
  • 41
    • 33845213347 scopus 로고    scopus 로고
    • Therapeutic intervention of experimental breast cancer bone metastasis by indole-3-carbinol in SCID-human mouse model
    • Rahman, K. M., et al. 2006. Therapeutic intervention of experimental breast cancer bone metastasis by indole-3-carbinol in SCID-human mouse model. Mol. Cancer Ther. 5:2747-2756.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 2747-2756
    • Rahman, K.M.1
  • 42
    • 20144389585 scopus 로고    scopus 로고
    • Transforming growth factor beta facilitates beta-TrCPmediated degradation of Cdc25A in a Smad3-dependent manner
    • Ray, D., et al. 2005. Transforming growth factor beta facilitates beta-TrCPmediated degradation of Cdc25A in a Smad3-dependent manner. Mol. Cell. Biol. 25:3338-3347.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 3338-3347
    • Ray, D.1
  • 43
    • 34547107624 scopus 로고    scopus 로고
    • Hemizygous disruption of Cdc25A inhibits cellular transformation and mammary tumorigenesis in mice
    • Ray, D., et al. 2007. Hemizygous disruption of Cdc25A inhibits cellular transformation and mammary tumorigenesis in mice. Cancer Res. 67:6605-6611.
    • (2007) Cancer Res. , vol.67 , pp. 6605-6611
    • Ray, D.1
  • 44
    • 33847308224 scopus 로고    scopus 로고
    • Inhibiting transient protein-protein interactions: lessons from the Cdc25 protein tyrosine phosphatases
    • Rudolph, J. 2007. Inhibiting transient protein-protein interactions: lessons from the Cdc25 protein tyrosine phosphatases. Nat. Rev. Cancer 7:202-211.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 202-211
    • Rudolph, J.1
  • 45
    • 52649133982 scopus 로고    scopus 로고
    • Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer
    • Sauter, W., et al. 2008. Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer. Cancer Epidemiol. Biomarkers Prev. 17:1127-1135.
    • (2008) Cancer Epidemiol. Biomarkers Prev. , vol.17 , pp. 1127-1135
    • Sauter, W.1
  • 46
    • 64249129547 scopus 로고    scopus 로고
    • Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site
    • Trivedi, V., et al. 2009. Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site. Cell 137:332-343.
    • (2009) Cell , vol.137 , pp. 332-343
    • Trivedi, V.1
  • 47
    • 34249281690 scopus 로고    scopus 로고
    • Stressing the role of FoxO proteins in lifespan and disease
    • van der Horst, A., and B. M. Burgering. 2007. Stressing the role of FoxO proteins in lifespan and disease. Nat. Rev. Mol. Cell Biol. 8:440-450.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 440-450
    • van der Horst, A.1    Burgering, B.M.2
  • 48
    • 58149214374 scopus 로고    scopus 로고
    • Aberrant Polo-like kinase 1-Cdc25A pathway in metastatic hepatocellular carcinoma
    • Wang, X. Q., et al. 2008. Aberrant Polo-like kinase 1-Cdc25A pathway in metastatic hepatocellular carcinoma. Clin. Cancer Res. 14:6813-6820.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 6813-6820
    • Wang, X.Q.1
  • 49
    • 33845383712 scopus 로고    scopus 로고
    • Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis
    • Wen, R., et al. 2006. Essential role of phospholipase C gamma 2 in early B-cell development and Myc-mediated lymphomagenesis. Mol. Cell. Biol. 26:9364-9376.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 9364-9376
    • Wen, R.1
  • 50
    • 0032530140 scopus 로고    scopus 로고
    • Overexpression of cdc25A and cdc25B is frequent in primary non-small cell lung cancer but is not associated with overexpression of c-myc
    • Wu, W., Y. H. Fan, B. L. Kemp, G. Walsh, and L. Mao. 1998. Overexpression of cdc25A and cdc25B is frequent in primary non-small cell lung cancer but is not associated with overexpression of c-myc. Cancer Res. 58:4082-4085.
    • (1998) Cancer Res. , vol.58 , pp. 4082-4085
    • Wu, W.1    Fan, Y.H.2    Kemp, B.L.3    Walsh, G.4    Mao, L.5
  • 51
    • 77954708496 scopus 로고    scopus 로고
    • A novel mechanism of indole-3-carbinol effects on breast carcinogenesis involves induction of Cdc25A degradation
    • Wu, Y., et al. 2010. A novel mechanism of indole-3-carbinol effects on breast carcinogenesis involves induction of Cdc25A degradation. Cancer Prev. Res. 3:818-828.
    • (2010) Cancer Prev. Res. , vol.3 , pp. 818-828
    • Wu, Y.1
  • 52
    • 53949087832 scopus 로고    scopus 로고
    • Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt
    • Yamagata, K., et al. 2008. Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt. Mol. Cell 32:221-231.
    • (2008) Mol. Cell , vol.32 , pp. 221-231
    • Yamagata, K.1
  • 53
    • 68049143326 scopus 로고    scopus 로고
    • Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis
    • Yang, E., et al. 2009. Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis. Cancer Res. 69:6223-6231.
    • (2009) Cancer Res. , vol.69 , pp. 6223-6231
    • Yang, E.1
  • 54
    • 41149160386 scopus 로고    scopus 로고
    • Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons
    • Yuan, Z., et al. 2008. Activation of FOXO1 by Cdk1 in cycling cells and postmitotic neurons. Science 319:1665-1668.
    • (2008) Science , vol.319 , pp. 1665-1668
    • Yuan, Z.1
  • 55
    • 0037069326 scopus 로고    scopus 로고
    • Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints
    • Zhao, H., J. L. Watkins, and H. Piwnica-Worms. 2002. Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints. Proc. Natl. Acad. Sci. U. S. A. 99: 14795-14800.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 14795-14800
    • Zhao, H.1    Watkins, J.L.2    Piwnica-Worms, H.3
  • 56
    • 0037112178 scopus 로고    scopus 로고
    • Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence
    • Zou, X., et al. 2002. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence. Genes Dev. 16:2923-2934.
    • (2002) Genes Dev. , vol.16 , pp. 2923-2934
    • Zou, X.1
  • 57
    • 0034949255 scopus 로고    scopus 로고
    • The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1
    • Zou, X., et al. 2001. The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1. Mol. Cell. Biol. 21:4818-4828.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4818-4828
    • Zou, X.1


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