CDC 25A gene 263C/T, -350C/T, and -51C/G polymorphisms in breast carcinoma

Tumor Biology

Volumn 31, Issue 6, 2010, Pages 597-604

  Karagoz, Isik Didem ^a   Ozaslan, Mehmet ^a   Cengiz, Beyhan ^a   Kalender, Mehmet Emin ^a   Kilic, Ibrahim Halil ^a   Oztuzcu, Serdar ^a   Gogebakan, Bulent ^a   Demiryurek, Abdullah Tuncay ^a  

^a GAZIANTEP UNIVERSITY   (Turkey)

Author keywords

Breast cancer; CDC25A; Cell cycle; Polymorphism

Indexed keywords

ANTINEOPLASTIC AGENT; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE A; UNCLASSIFIED DRUG;

ADULT; AGE DISTRIBUTION; ARTICLE; BONE METASTASIS; BRAIN METASTASIS; BREAST CANCER; BREAST CARCINOMA; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CDC25A GENE; CONTROLLED STUDY; EXON; FAMILY HISTORY; FEMALE; GENE FREQUENCY; GENOTYPE; HISTOPATHOLOGY; HOMOZYGOSITY; HORMONE SUBSTITUTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER METASTASIS; LUNG METASTASIS; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; METASTASIS POTENTIAL; NUCLEOTIDE SEQUENCE; ONCOGENE; PLEURA METASTASIS; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 78449252760     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-010-0075-z     Document Type: Article

References (21)

1. Gürtunç E: Meme Kanserli Hastalarda CYP19 Geni Kodon 39 Trp/Arg Polimorfizminin ve Genotip DaǧIlImInIn AraştIrIlmasI. Yüksek Lisans Tezi. Çukurova Üniv SaǧlIk Bilimleri Ens TIbbi Biyoloji ABD 2007.
2. YIldIz Y: Meme Kanserli Hastalarda TNF ile İlişkili Apoptoz UyarIcI Ligand ve Bcl-2 ile İlişkili X-Protein Gen Polimorfizmlerinin AraştIrIlmasI. Yüksek Lisans Tezi. İstanbul Üniv SaǧlIk Bilimleri Ens Moleküler TIp ABD 2008.
3. H Ma Z Hu X Zhai S Wang X Wang J Qin, et al. 2006 Polymorphisms in the MDM2 promoter and risk of breast cancer: a case-control analysis in a Chinese population Cancer Lett 240 261 7 1:CAS:528:DC%2BD28XntlGjurs%3D 10.1016/j.canlet.2005.09.019 16288830
4. Hossfeld DK, Sherman CD, Love RR, Bosch FX: Klinik Onkoloji. UluslararasI Kanserle Savaş Birliǧi 1992; 5th edition, p 25.
5. R Boutros V Lobjois B Ducommun 2007 CDC25 phosphatases in cancer cells: key players? good targets? Nat Rev Cancer 7 495 507 1:CAS:528: DC%2BD2sXmvVakurg%3D 10.1038/nrc2169 17568790
6. MG Cangi B Cukor P Soung S Signoretti G Moreira Jr M Ranashinge, et al. 2000 Role of the CDC25A phosphatase in human breast cancer J Clin Invest 106 753 61 1:CAS:528:DC%2BD3cXms1Cgsbo%3D 10.1172/JCI9174 10995786
7. S Jinno K Suto A Nagata M Igarashi Y Kanaoka H Nojima, et al. 1994 CDC25A is a novel phosphatase functioning early in the cell cycle EMBO J 13 1549 56 1:CAS:528:DyaK2cXkt1ymtLo%3D 8156993
8. 1/S transition EMBO J 13 4302 10 1:CAS:528:DyaK2cXmslOmsrw%3D 7523110
9. R Boutros C Dozier B Ducommun 2006 The when and wheres of CDC25 phosphatases Curr Opin Cell Biol 18 185 91 1:CAS:528:DC%2BD28Xit1Chsbk%3D 10.1016/j.ceb.2006.02.003 16488126
10. M Molinari C Mercurio J Dominguez F Goubin GF Draetta 2000 Human CDC25A inactivation in response to S time inhibition and its role in preventing premature mitosis EMBO Rep 1 71 9 1:CAS:528:DC%2BD3cXmtl2ns7o%3D 10.1093/embo-reports/kvd018 11256629
11. D Gasparotto R Maestro S Piccinin T Vukosavljevic L Barzan S Sulfaro, et al. 1997 Overexpression of CDC25A and CDC25B in head and neck cancers Cancer Res 57 2366 8 1:CAS:528:DyaK2sXjvFKit7Y%3D 9192810
12. S Hernandez L Hernandez S Bea M Cazorla PL Fernandez A Nadal, et al. 1998 CDC25 cell cycle-activating phosphatases and c-myc expression in human non-Hodgkin's lymphomas Cancer Res 58 1762 7 1:CAS:528:DyaK1cXisleru70%3D 9563496
13. Y Kudo W Yasui T Ue S Yamamoto H Yokozaki H Nikai, et al. 1997 Overexpression of cyclin-dependent kinase-activating CDC25B phosphatase in human gastric carcinomas Jpn J Cancer Res 88 947 52 1:CAS:528:DyaK2sXnt1Cqu7s%3D 9414655
14. W Wu Y Fan B Kemp G Walsh L Mao 1998 Overexpression of CDC25A and CDC25B is frequent in primary non-small cell lung cancer but is not associated with overexpression of c-myc Cancer Res 58 4082 5 1:CAS:528:DyaK1cXmtlCksrY%3D 9751615
15. G Moreira Jr GWB Colleoni MG Cangi M Murphy B Sherburne, et al. 2003 Reciprocal CDC25A and p27 expression in B-cell non-Hodgkin lymphomas Diagn Mol Pathol 12 3 128 32
16. S Hernandez X Bessa S Bea L Hernandez A Nadal C Mallofre, et al. 2001 Differential expression of CDC25 cell-cycle-activating phosphatases in human colorectal carcinoma Lab Invest 81 465 73 1:CAS:528:DC%2BD3MXjsFSis7o%3D 11304565
17. D Ray H Kiyokama 2008 CDC25A phosphatase: a rate-limiting oncogene that determines genomic stability Cancer Res 68 5 1251 3 1:CAS:528: DC%2BD1cXislagtLk%3D 10.1158/0008-5472.CAN-07-5983 18316586
18. MG Cangi S Piccinin L Pecciarini A Talarico ED Cin S Grassi, et al. 2008 Constitutive overexpression of CDC25A in primary human mammary epithelial cells results in both defective DNA damage response and chromosomal breaks at fragile sites Int J Cancer 123 1466 71 1:CAS:528:DC%2BD1cXhtVCltLrJ 10.1002/ijc.23659 18566993
19. http://atlasgeneticsoncology.org/Genes/CDC25AID40004ch3p21.html (access date:18 May 2010)
20. D Cozma L Lukes J Rouse TH Qiu ET Liu KW Hunter 2002 A bioinformatics-based strategy identifies c-Myc and CDC25A as candidates for the Apmt mammary tumour latency modifiers Genome Res 12 969 75 1:CAS:528: DC%2BD38Xks12hs7w%3D 10.1101/gr.210502 12045150
21. Y Ito H Yoshida T Uruno Y Takamura A Miya K Kuma, et al. 2004 Expression of CDC25A and CDC25B phosphatase in breast carcinoma Breast Cancer 11 295 300 10.1007/BF02984552 15550849