Analyses of benzodiazepines and their metabolites in various biological matrices by LC-MS(/MS)

Biomedical Chromatography

Volumn 25, Issue 12, 2011, Pages 1283-1307

  Nakamura, Mitsuhiro ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Benzodiazepines; Liquid chromatography; Liquid liquid extraction; Solid phase extraction; Tandem mass spectrometry

Indexed keywords

BIOMOLECULES; BODY FLUIDS; FORENSIC SCIENCE; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHASE SEPARATION; SOLVENT EXTRACTION;

ANTIEPILEPTICS; BENZODIAZEPINES; BIOLOGICAL MATRIXES; LC-MS-MS; LIQUID-LIQUID EXTRACTION; MUSCLE RELAXANTS; PROPERTY; SOLID-PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; TANDEM-MASS SPECTROMETRY;

METABOLITES;

7 ACETAMIDO 1,3 DIHYDRO 5 PHENYL 2H 1,4 BENZODIAZEPIN 2 ONE; 7 AMINO 1,3 DIHYDRO 5 PHENYL 2H 1,4 BENZODIAZEPIN 2 ONE; 7 AMINOCLONAZEPAM; 7 AMINOFLUNITRAZEPAM; ALPHA HYDROXYALPRAZOLAM; ALPHA HYDROXYETHYLFLURAZEPAM; ALPHA HYDROXYTRIAZOLAM; ALPRAZOLAM; BENZODIAZEPINE DERIVATIVE; BROMAZEPAM; BROTIZOLAM; CHLORDIAZEPOXIDE; CLOBAZAM; CLONAZEPAM; DIAZEPAM; DRUG METABOLITE; ESTAZOLAM; FLUDIAZEPAM; FLUNITRAZEPAM; FLURAZEPAM; LORAZEPAM; NITRAZEPAM; NORCLOBAZAM; NORDAZEPAM; OXAZEPAM; PRAZEPAM; QUAZEPAM; TEMAZEPAM; TRIAZOLAM; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANALYTIC METHOD; BODY FLUID; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STRUCTURE; DRUG URINE LEVEL; HUMAN; LIQUID CHROMATOGRAPHY; QUANTITATIVE ASSAY; REVIEW; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY; TECHNIQUE;

EID: 79961129312     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1598     Document Type: Review

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