The detection and quantification of lorazepam and its 3-O-glucuronide in fingerprint deposits by LC-MS/MS

Journal of Separation Science

Volumn 32, Issue 13, 2009, Pages 2266-2272

  Goucher, Edward ^a   Kicman, Andrew ^a   Smith, Norman ^a   Jickells, Sue ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Fingerprint deposits; HILIC MS MS; Lorazepam glucuronide; Quantitative analysis

Indexed keywords

ANALYTICAL TOXICOLOGY; BIOLOGICAL MATRIXES; DRUG ADMINISTRATION; FINGERPRINT DEPOSITS; GLASS COVERS; GLUCURONIDES; HILIC-MS/MS; HYDROPHILIC INTERACTION; INTERNAL STANDARDS; LC-MS/MS; LORAZEPAM; LORAZEPAM GLUCURONIDE; MOBILE PHASE; ORAL ADMINISTRATION; QUANTITATIVE ANALYSIS;

CHROMATOGRAPHIC ANALYSIS; DEPOSITS; DISSOLUTION; HYDROPHILICITY; LIQUID CHROMATOGRAPHY; TOXICITY;

COLUMN CHROMATOGRAPHY;

CREATININE; DICHLOROMETHANE; DRUG METABOLITE; LORAZEPAM; LORAZEPAM 3 O GLUCURONIDE; METHANOL; UNCLASSIFIED DRUG; ANXIOLYTIC AGENT; DRUG DERIVATIVE; LORAZEPAM GLUCURONIDE;

ADULT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DETERMINATION; DRUG METABOLISM; DRUG STRUCTURE; DRUG TISSUE LEVEL; FEMALE; FINGER DERMATOGLYPHICS; HUMAN; HUMAN EXPERIMENT; HYDROPHILICITY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; METABOLITE; NORMAL HUMAN; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SINGLE DRUG DOSE; CHEMICAL STRUCTURE; CHEMISTRY; DERMATOGLYPHICS; EVALUATION; INSTRUMENTATION; METABOLISM; METHODOLOGY; SECRETION; SKIN; TANDEM MASS SPECTROMETRY;

ADULT; ANTI-ANXIETY AGENTS; CHROMATOGRAPHY, LIQUID; CREATININE; DERMATOGLYPHICS; FEMALE; HUMANS; LORAZEPAM; MALE; MOLECULAR STRUCTURE; SKIN; TANDEM MASS SPECTROMETRY; YOUNG ADULT;

EID: 70149119530     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200900097     Document Type: Article

References (31)

1. Karch, S., Drugs Abuse Handbook, Chapter (10) 5.2-3, 2nd Edn., CRC Press, Boca Raton, FL 2007.
2. Balikova, M., Biomed. Pap. Med. Fac. Univ. Palacky. Olomouc Czech Repub. 2005, 149, 199-207.
3. Oiestad, E. L., Johansen, U., Christophersen, A. S., Clin. Chem. 2007, 53, 300-309.
4. Dams, R., Choo, R. E., Lambert, W. E., Jones, H., Huestis, M. A., Drug Alcohol Depend. 2007, 87, 258-267.
5. Caplan, Y. H., Goldberger, B. A., J. Anal. Toxicol. 2001, 25, 396-399.
6. Kidwell, D. A., Holland, J. C., Athanaselis, S., J. Chromatogr. B: Biomed. Sci. Appl. 1998, 713, 111-135.
7. Johnson, H. L., Maibach, H. I., J. Invest. Dermatol. 1971, 56, 182-188.
8. George, S., Occup. Med. (Lond) 2005, 55, 69-71.
9. Schutz, H., Z. Rechtsmed. 1988, 100, 19-37.
10. Kintz, P., Villain, M., Cirimele, V., Pepin, G., Ludes, B., Forensic Sci. Int. 2004, 145, 131-135.
11. Kidwell, D. A., Kidwell, J. D., Shinohara, F., Harper, C., Roarty, K., Bernadt, K., McCaulley, R. A., Smith, F. P., Forensic Sci. Int. 2003, 133, 63-78.
12. Kidwell, D. A., Smith, F. P., Forensic Sci. Int. 2001, 116, 89-106.
13. Russell, D. A., Angew. Chem., Int. Ed. 2007, 46, 4100-4103.
14. Ifa, D. R., Manicke, N. E., Dill, A. L., Cooks, R. G., Science 2008, 321, 805.
15. Day, J. S., Edwards, H. G., Dobrowski, S. A., Voice, A. M., Spectrochim. Acta A Mol. Biomol. Spectrosc. 2004, 60, 1725-1730.
16. Day, J. S., Edwards, H. G., Dobrowski, S. A., Voice, A. M., Spectrochim. Acta A Mol. Biomol. Spectrosc. 2004, 60, 563-568.
17. West, M. J., Went, M. J., Spectrochim. Acta A Mol. Biomol. Spectrosc. 2008, 71, 1984-1988.
18. Jacob, S., Jickells, S., Wolff, K., Smith, N., Drug Metab. Lett. 2008, 2, 245-247.
19. Hazarika, P., Jickells, S. M., Wolff, K., Russell, D. A., Angew. Chem., Int. Ed. 2008, 47, 10167-10170.
20. Funderburk, F. R., Griffiths, R. R., McLeod, D. R., Bigelow, G. E., Mackenzie, A., Liebson, I. A., Nemeth-Coslett, R., Drug Alcohol Depend. 1988, 22, 215-222.
21. Orzack, M. H., Friedman, L., Dessain, E., Bird, M., Beake, B., McEachern, J., Cole, J. O., Int. J. Addict. 1988, 23, 449-467.
22. Ayadi, N., Neifar, S., Maalej, M., Therapie 1998, 53, 596-598.
23. Bratzke, H., Klug, E., Arch. Kriminol. 1988, 181, 33-40.
24. Baldacci, A., Thormann, W., J. Sep. Sci. 2006, 29, 153-163.
25. Elliott, H. W., Br. J. Anaesth. 1976, 48, 1017-1023.
26. Greenblatt, D. J., Shader, R. I., Franke, K., MacLaughlin, D. S., Harmatz, J. S., Allen,M. D., Werner, A., Woo, E., J. Pharm. Sci. 1979, 68, 57-63.
27. Archer, N. E., Charles, Y., Elliott, J. A., Jickells, S., Forensic Sci. Int. 2005, 154, 224-239.
28. Baselt, R. C., in: Disposition of Toxic Drugs and Chemicals in Man, 7th Edn., Vol. 7, Biomedical Publications, Foster City, CA 2004.
29. Emrich, H. M., Stoll, E., Friolet, B., Colombo, J. P., Richterich, R., Rossi, E., Pediatr. Res. 1968, 2, 464-478.
30. Justes, D. R., Talaty, N., Cotte-Rodriguez, I., Cooks, R. G., Chem. Commun. (Camb.) 2007, 2142-2144.
31. Schummer, C., Appenzeller, B. M., Wennig, R., Ther. Drug Monit. 2008, 30, 536-539.