메뉴 건너뛰기




Volumn 55, Issue 4-5, 2011, Pages 483-494

Molecular mechanisms of lymphangiogenesis in development and cancer

Author keywords

Angiogenesis; Cancer; Development; Lymphangiogenesis; Metastasis; Signaling

Indexed keywords

VASCULOTROPIN C; VASCULOTROPIN D; VASCULOTROPIN RECEPTOR 3;

EID: 79961004610     PISSN: 02146282     EISSN: None     Source Type: Journal    
DOI: 10.1387/ijdb.103226ia     Document Type: Article
Times cited : (61)

References (135)
  • 2
    • 24344451690 scopus 로고    scopus 로고
    • The effects of interleukin-7 on the lymphangiogenic properties of human endothelial cells
    • AL-RAWI MA, WATKINS G, MANSEL RE, JIANG WG (2005). The effects of interleukin-7 on the lymphangiogenic properties of human endothelial cells. Int J Oncol 27: 721-730.
    • (2005) Int J Oncol , vol.27 , pp. 721-730
    • Al-Rawi, M.A.1    Watkins, G.2    Mansel, R.E.3    Jiang, W.G.4
  • 4
    • 60749096085 scopus 로고    scopus 로고
    • Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system
    • AUGUSTIN HG, KOH GY, THURSTON G, ALITALO K (2009). Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Nat Rev Mol Cell Biol 10: 165-177.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 165-177
    • Augustin, H.G.1    Koh, G.Y.2    Thurston, G.3    Alitalo, K.4
  • 7
    • 0033593793 scopus 로고    scopus 로고
    • LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan
    • BANERJI S, NI J, WANG SX, CLASPER S, SU J, TAMMI R, JONES M, JACKSON DG (1999). LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J Cell Biol 144: 789-801.
    • (1999) J Cell Biol , vol.144 , pp. 789-801
    • Banerji, S.1    Ni, J.2    Wang, S.X.3    Clasper, S.4    Su, J.5    Tammi, R.6    Jones, M.7    Jackson, D.G.8
  • 11
    • 27144524895 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-a promotes peritumoral lymphangiogenesis and lymphatic metastasis
    • BJORNDAHL MA, CAO R, BURTON JB, BRAKENHIELM E, RELIGA P, GALTER D, WU L, CAO Y (2005b). Vascular endothelial growth factor-a promotes peritumoral lymphangiogenesis and lymphatic metastasis. Cancer Res 65: 9261-9268.
    • (2005) Cancer Res , vol.65 , pp. 9261-9268
    • Bjorndahl, M.A.1    Cao, R.2    Burton, J.B.3    Brakenhielm, E.4    Religa, P.5    Galter, D.6    Wu, L.7    Cao, Y.8
  • 15
    • 43549094221 scopus 로고    scopus 로고
    • Proliferating mesodermal cells in murine embryos exhibiting macrophage and lymphendothelial characteristics
    • BUTTLER K, EZAKI T, WILTING J (2008). Proliferating mesodermal cells in murine embryos exhibiting macrophage and lymphendothelial characteristics. BMC Dev Biol 8: 43.
    • (2008) BMC Dev Biol , vol.8 , pp. 43
    • Buttler, K.1    Ezaki, T.2    Wilting, J.3
  • 26
    • 27744573043 scopus 로고    scopus 로고
    • Deletion of peptide amidation enzymatic activity leads to edema and embryonic lethality in the mouse
    • CZYZYK TA, NING Y, HSU MS, PENG B, MAINS RE, EIPPER BA, PINTAR JE (2005). Deletion of peptide amidation enzymatic activity leads to edema and embryonic lethality in the mouse. Dev Biol 287: 301-313.
    • (2005) Dev Biol , vol.287 , pp. 301-313
    • Czyzyk, T.A.1    Ning, Y.2    Hsu, M.S.3    Peng, B.4    Mains, R.E.5    Eipper, B.A.6    Pintar, J.E.7
  • 29
    • 46049111407 scopus 로고    scopus 로고
    • Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice
    • DELLINGER M, HUNTER R, BERNAS M, GALE N, YANCOPOULOS G, ERICKSON R, WITTE M (2008). Defective remodeling and maturation of the lymphatic vasculature in Angiopoietin-2 deficient mice. Dev Biol 319: 309-320.
    • (2008) Dev Biol , vol.319 , pp. 309-320
    • Dellinger, M.1    Hunter, R.2    Bernas, M.3    Gale, N.4    Yancopoulos, G.5    Erickson, R.6    Witte, M.7
  • 33
    • 0033646615 scopus 로고    scopus 로고
    • Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome
    • FANG J, DAGENAIS SL, ERICKSON RP, ARLT MF, GLYNN MW, GORSKI JL, SEAVER LH, GLOVER TW (2000). Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome. Am J Hum Genet 67: 1382-1388.
    • (2000) Am J Hum Genet , vol.67 , pp. 1382-1388
    • Fang, J.1    Dagenais, S.L.2    Erickson, R.P.3    Arlt, M.F.4    Glynn, M.W.5    Gorski, J.L.6    Seaver, L.H.7    Glover, T.W.8
  • 36
    • 38149064606 scopus 로고    scopus 로고
    • Adrenomedullin signaling is necessary for murine lymphatic vascular development
    • FRITZ-SIX KL, DUNWORTH WP, LI M, CARON KM (2008). Adrenomedullin signaling is necessary for murine lymphatic vascular development. J Clin Invest 118: 40-50.
    • (2008) J Clin Invest , vol.118 , pp. 40-50
    • Fritz-Six, K.L.1    Dunworth, W.P.2    Li, M.3    Caron, K.M.4
  • 40
    • 33947494918 scopus 로고    scopus 로고
    • Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis
    • HARRELL MI, IRITANI BM, RUDDELL A (2007). Tumor-induced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis. Am J Pathol 170: 774-786.
    • (2007) Am J Pathol , vol.170 , pp. 774-786
    • Harrell, M.I.1    Iritani, B.M.2    Ruddell, A.3
  • 41
    • 0037024472 scopus 로고    scopus 로고
    • Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling
    • HE Y, KOZAKI K, KARPANEN T, KOSHIKAWA K, YLA-HERTTUALA S, TAKAHASHI T, ALITALO K (2002). Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling. J Natl Cancer Inst 94: 819-825.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 819-825
    • He, Y.1    Kozaki, K.2    Karpanen, T.3    Koshikawa, K.4    Yla-Herttuala, S.5    Takahashi, T.6    Alitalo, K.7
  • 42
    • 2542512275 scopus 로고    scopus 로고
    • Preexisting lymphatic endothelium but not endothelial progenitor cells are essential for tumor lymphangiogenesis and lymphatic metastasis
    • HE Y, RAJANTIE I, ILMONEN M, MAKINEN T, KARKKAINEN MJ, HAIKO P, SALVEN P, ALITALO K (2004). Preexisting lymphatic endothelium but not endothelial progenitor cells are essential for tumor lymphangiogenesis and lymphatic metastasis. Cancer Res 64: 3737-3740.
    • (2004) Cancer Res , vol.64 , pp. 3737-3740
    • He, Y.1    Rajantie, I.2    Ilmonen, M.3    Makinen, T.4    Karkkainen, M.J.5    Haiko, P.6    Salven, P.7    Alitalo, K.8
  • 43
    • 33846857321 scopus 로고    scopus 로고
    • VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites
    • HIRAKAWA S, BROWN LF, KODAMA S, PAAVONEN K, ALITALO K, DETMAR M (2007). VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites. Blood 109: 1010-1017.
    • (2007) Blood , vol.109 , pp. 1010-1017
    • Hirakawa, S.1    Brown, L.F.2    Kodama, S.3    Paavonen, K.4    Alitalo, K.5    Detmar, M.6
  • 45
    • 0037331713 scopus 로고    scopus 로고
    • Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells
    • HIRAKAWA S, HONG YK, HARVEY N, SCHACHT V, MATSUDA K, LIBERMANN T, DETMAR M (2003). Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells. Am J Pathol 162: 575-586.
    • (2003) Am J Pathol , vol.162 , pp. 575-586
    • Hirakawa, S.1    Hong, Y.K.2    Harvey, N.3    Schacht, V.4    Matsuda, K.5    Libermann, T.6    Detmar, M.7
  • 46
    • 17144402207 scopus 로고    scopus 로고
    • VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis
    • HIRAKAWA S, KODAMA S, KUNSTFELD R, KAJIYA K, BROWN LF, DETMAR M (2005). VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis. J Exp Med 201: 1089-1099.
    • (2005) J Exp Med , vol.201 , pp. 1089-1099
    • Hirakawa, S.1    Kodama, S.2    Kunstfeld, R.3    Kajiya, K.4    Brown, L.F.5    Detmar, M.6
  • 47
  • 50
    • 0036840138 scopus 로고    scopus 로고
    • Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate
    • HONG YK, HARVEY N, NOH YH, SCHACHT V, HIRAKAWA S, DETMAR M, OLIVER G (2002). Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate. Dev Dyn 225: 351-357.
    • (2002) Dev Dyn , vol.225 , pp. 351-357
    • Hong, Y.K.1    Harvey, N.2    Noh, Y.H.3    Schacht, V.4    Hirakawa, S.5    Detmar, M.6    Oliver, G.7
  • 51
    • 42749085069 scopus 로고    scopus 로고
    • Intratumoral lymphatics and lymphatic invasion are associated with tumor aggressiveness and poor prognosis in renal cell carcinoma
    • HORIGUCHI A, ITO K, SUMITOMO M, KIMURA F, ASANO T, HAYAKAWA M (2008). Intratumoral lymphatics and lymphatic invasion are associated with tumor aggressiveness and poor prognosis in renal cell carcinoma. Urology 71: 928-932.
    • (2008) Urology , vol.71 , pp. 928-932
    • Horiguchi, A.1    Ito, K.2    Sumitomo, M.3    Kimura, F.4    Asano, T.5    Hayakawa, M.6
  • 52
    • 33748075460 scopus 로고    scopus 로고
    • Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: Therapeutic implications
    • HOSHIDA T, ISAKA N, HAGENDOORN J, DI TOMASO E, CHEN YL, PYTOWSKI B, FUKUMURA D, PADERA TP, JAIN RK (2006). Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications. Cancer Res 66: 8065-8075.
    • (2006) Cancer Res , vol.66 , pp. 8065-8075
    • Hoshida, T.1    Isaka, N.2    Hagendoorn, J.3    Di Tomaso, E.4    Chen, Y.L.5    Pytowski, B.6    Fukumura, D.7    Padera, T.P.8    Jain, R.K.9
  • 53
    • 84979135129 scopus 로고
    • The anatomy and development of the jugular lymph sacs in the domestic cat (Felis domestica)
    • HUNTINGTON GS, MCCLURE CFW (1908). The anatomy and development of the jugular lymph sacs in the domestic cat (Felis domestica). Anat Rec 2: 1-18.
    • (1908) Anat Rec , vol.2 , pp. 1-18
    • Huntington, G.S.1    McClure, C.F.W.2
  • 54
    • 62349108155 scopus 로고    scopus 로고
    • Phospholipase Cgamma2 is necessary for separation of blood and lymphatic vasculature in mice
    • ICHISE H, ICHISE T, OHTANI O, YOSHIDA N (2009). Phospholipase Cgamma2 is necessary for separation of blood and lymphatic vasculature in mice. Development 136: 191-195.
    • (2009) Development , vol.136 , pp. 191-195
    • Ichise, H.1    Ichise, T.2    Ohtani, O.3    Yoshida, N.4
  • 55
    • 34249650289 scopus 로고    scopus 로고
    • Hypoxia alters the adhesive properties of lymphatic endothelial cells. A transcriptional and functional study
    • IRIGOYEN M, ANSO E, MARTINEZ E, GARAYOA M, MARTINEZ-IRUJO JJ, ROUZAUT A (2007). Hypoxia alters the adhesive properties of lymphatic endothelial cells. A transcriptional and functional study. Biochim Biophys Acta 1773: 880-890.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 880-890
    • Irigoyen, M.1    Anso, E.2    Martinez, E.3    Garayoa, M.4    Martinez-Irujo, J.J.5    Rouzaut, A.6
  • 56
    • 0043136701 scopus 로고    scopus 로고
    • Mannose receptor (MR) and common lymphatic endothelial and vascular endothelial receptor (CLEVER)-1 direct the binding of cancer cells to the lymph vessel endothelium
    • IRJALA H, ALANEN K, GRENMAN R, HEIKKILA P, JOENSUU H, JALKANEN S (2003). Mannose receptor (MR) and common lymphatic endothelial and vascular endothelial receptor (CLEVER)-1 direct the binding of cancer cells to the lymph vessel endothelium. Cancer Res 63: 4671-4676.
    • (2003) Cancer Res , vol.63 , pp. 4671-4676
    • Irjala, H.1    Alanen, K.2    Grenman, R.3    Heikkila, P.4    Joensuu, H.5    Jalkanen, S.6
  • 57
    • 0033862310 scopus 로고    scopus 로고
    • Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase
    • IRRTHUM A, KARKKAINEN MJ, DEVRIENDT K, ALITALO K, VIKKULA M (2000). Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase. Am J Hum Genet 67: 295-301.
    • (2000) Am J Hum Genet , vol.67 , pp. 295-301
    • Irrthum, A.1    Karkkainen, M.J.2    Devriendt, K.3    Alitalo, K.4    Vikkula, M.5
  • 58
    • 58249124355 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-C and C-C chemokine receptor 7 in tumor cell-lymphatic cross-talk promote invasive phenotype
    • ISSA A, LE TX, SHOUSHTARI AN, SHIELDS JD, SWARTZ MA (2009). Vascular endothelial growth factor-C and C-C chemokine receptor 7 in tumor cell-lymphatic cross-talk promote invasive phenotype. Cancer Res 69: 349-357.
    • (2009) Cancer Res , vol.69 , pp. 349-357
    • Issa, A.1    Le, T.X.2    Shoushtari, A.N.3    Shields, J.D.4    Swartz, M.A.5
  • 62
    • 56549093824 scopus 로고    scopus 로고
    • Adrenomedullin induces lymphangiogenesis and ameliorates secondary lymphoedema
    • JIN D, HARADA K, OHNISHI S, YAMAHARA K, KANGAWA K, NAGAYA N (2008). Adrenomedullin induces lymphangiogenesis and ameliorates secondary lymphoedema. Cardiovasc Res 80: 339-345.
    • (2008) Cardiovasc Res , vol.80 , pp. 339-345
    • Jin, D.1    Harada, K.2    Ohnishi, S.3    Yamahara, K.4    Kangawa, K.5    Nagaya, N.6
  • 64
    • 30544452034 scopus 로고    scopus 로고
    • Hepatocyte growth factor promotes lymphatic vessel formation and function
    • KAJIYA K, HIRAKAWA S, MA B, DRINNENBERG I, DETMAR M (2005). Hepatocyte growth factor promotes lymphatic vessel formation and function. EMBO J 24: 2885-2895.
    • (2005) EMBO J , vol.24 , pp. 2885-2895
    • Kajiya, K.1    Hirakawa, S.2    Ma, B.3    Drinnenberg, I.4    Detmar, M.5
  • 73
    • 0037172970 scopus 로고    scopus 로고
    • Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea
    • KUBO H, CAO R, BRAKENHIELM E, MAKINEN T, CAO Y, ALITALO K (2002). Blockade of vascular endothelial growth factor receptor-3 signaling inhibits fibroblast growth factor-2-induced lymphangiogenesis in mouse cornea. Proc Natl Acad Sci USA 99: 8868-8873.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8868-8873
    • Kubo, H.1    Cao, R.2    Brakenhielm, E.3    Makinen, T.4    Cao, Y.5    Alitalo, K.6
  • 75
    • 74649086696 scopus 로고    scopus 로고
    • Increased intratumoral lymphatic vessel density correlates with lymph node metastasis in early gastric carcinoma
    • LEE K, PARK DO J, CHOE G, KIM HH, KIM WH, LEE HS (2010). Increased intratumoral lymphatic vessel density correlates with lymph node metastasis in early gastric carcinoma. Ann Surg Oncol 17: 73-80.
    • (2010) Ann Surg Oncol , vol.17 , pp. 73-80
    • Lee, K.1    Park, D.J.2    Choe, G.3    Kim, H.H.4    Kim, W.H.5    Lee, H.S.6
  • 76
    • 61849097153 scopus 로고    scopus 로고
    • Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate
    • LEE S, KANG J, YOO J, GANESAN SK, COOK SC, AGUILAR B, RAMU S, LEE J, HONG YK (2009). Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate. Blood 113: 1856-1859.
    • (2009) Blood , vol.113 , pp. 1856-1859
    • Lee, S.1    Kang, J.2    Yoo, J.3    Ganesan, S.K.4    Cook, S.C.5    Aguilar, B.6    Ramu, S.7    Lee, J.8    Hong, Y.K.9
  • 77
    • 65549110445 scopus 로고    scopus 로고
    • Vascular endothelial growth factor D and intratumoral lymphatics as independent prognostic factors in epithelial ovarian carcinoma
    • LI L, LIU B, LI X, YANG S, XIAO J, CHEN M, ZHANG Y, MA J (2009). Vascular endothelial growth factor D and intratumoral lymphatics as independent prognostic factors in epithelial ovarian carcinoma. Anat Rec (Hoboken) 292: 562-569.
    • (2009) Anat Rec (Hoboken) , vol.292 , pp. 562-569
    • Li, L.1    Liu, B.2    Li, X.3    Yang, S.4    Xiao, J.5    Chen, M.6    Zhang, Y.7    Ma, J.8
  • 78
    • 77951847278 scopus 로고    scopus 로고
    • Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development
    • LIN FJ, CHEN X, QIN J, HONG YK, TSAI MJ, TSAI SY (2010). Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development. J Clin Invest 120: 1694-1707.
    • (2010) J Clin Invest , vol.120 , pp. 1694-1707
    • Lin, F.J.1    Chen, X.2    Qin, J.3    Hong, Y.K.4    Tsai, M.J.5    Tsai, S.Y.6
  • 79
    • 63749125392 scopus 로고    scopus 로고
    • VEGFs and receptors involved in angiogenesis versus lymphangiogenesis
    • LOHELA M, BRY M, TAMMELA T, ALITALO K (2009). VEGFs and receptors involved in angiogenesis versus lymphangiogenesis. Curr Opin Cell Biol 21: 154-165.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 154-165
    • Lohela, M.1    Bry, M.2    Tammela, T.3    Alitalo, K.4
  • 85
    • 0037093242 scopus 로고    scopus 로고
    • Expression of chemokine receptor CCR7 is associated with lymph node metastasis of gastric carcinoma
    • MASHINO K, SADANAGA N, YAMAGUCHI H, TANAKA F, OHTA M, SHIBUTA K, INOUE H, MORI M (2002). Expression of chemokine receptor CCR7 is associated with lymph node metastasis of gastric carcinoma. Cancer Res 62: 2937-2941.
    • (2002) Cancer Res , vol.62 , pp. 2937-2941
    • Mashino, K.1    Sadanaga, N.2    Yamaguchi, H.3    Tanaka, F.4    Ohta, M.5    Shibuta, K.6    Inoue, H.7    Mori, M.8
  • 88
    • 0038825157 scopus 로고    scopus 로고
    • Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan
    • MURO AF, CHAUHAN AK, GAJOVIC S, IACONCIG A, PORRO F, STANTA G, BARALLE FE (2003). Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan. J Cell Biol 162: 149-160.
    • (2003) J Cell Biol , vol.162 , pp. 149-160
    • Muro, A.F.1    Chauhan, A.K.2    Gajovic, S.3    Iaconcig, A.4    Porro, F.5    Stanta, G.6    Baralle, F.E.7
  • 90
    • 46249101229 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 expression correlates with lymph node metastasis in pancreatic cancer
    • NAKATA B, FUKUNAGA S, NODA E, AMANO R, YAMADA N, HIRAKAWA K (2008). Chemokine receptor CCR7 expression correlates with lymph node metastasis in pancreatic cancer. Oncology 74: 69-75.
    • (2008) Oncology , vol.74 , pp. 69-75
    • Nakata, B.1    Fukunaga, S.2    Noda, E.3    Amano, R.4    Yamada, N.5    Hirakawa, K.6
  • 91
    • 37149014854 scopus 로고    scopus 로고
    • Differential gene expression of primary cultured lymphatic and blood vascular endothelial cells
    • NELSON GM, PADERA TP, GARKAVTSEV I, SHIODA T, JAIN RK (2007). Differential gene expression of primary cultured lymphatic and blood vascular endothelial cells. Neoplasia 9: 1038-1045.
    • (2007) Neoplasia , vol.9 , pp. 1038-1045
    • Nelson, G.M.1    Padera, T.P.2    Garkavtsev, I.3    Shioda, T.4    Jain, R.K.5
  • 92
    • 77949898210 scopus 로고    scopus 로고
    • ALK1 signaling regulates early postnatal lymphatic vessel development
    • NIESSEN K, ZHANG G, RIDGWAY JB, CHEN H, YAN M (2010). ALK1 signaling regulates early postnatal lymphatic vessel development. Blood 115: 1654-1661.
    • (2010) Blood , vol.115 , pp. 1654-1661
    • Niessen, K.1    Zhang, G.2    Ridgway, J.B.3    Chen, H.4    Yan, M.5
  • 93
    • 63649101806 scopus 로고    scopus 로고
    • A mechanism of sialylation functionally silences the hyaluronan receptor LYVE-1 in lymphatic endothelium
    • NIGHTINGALE TD, FRAYNE ME, CLASPER S, BANERJI S, JACKSON DG (2009). A mechanism of sialylation functionally silences the hyaluronan receptor LYVE-1 in lymphatic endothelium. J Biol Chem 284: 3935-3945.
    • (2009) J Biol Chem , vol.284 , pp. 3935-3945
    • Nightingale, T.D.1    Frayne, M.E.2    Clasper, S.3    Banerji, S.4    Jackson, D.G.5
  • 101
    • 0028867704 scopus 로고
    • The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells
    • PURI MC, ROSSANT J, ALITALO K, BERNSTEIN A, PARTANEN J (1995). The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells. EMBO J 14: 5884-5891.
    • (1995) EMBO J , vol.14 , pp. 5884-5891
    • Puri, M.C.1    Rossant, J.2    Alitalo, K.3    Bernstein, A.4    Partanen, J.5
  • 102
    • 28844505689 scopus 로고    scopus 로고
    • Presence of bone marrow-derived circulating progenitor endothelial cells in the newly formed lymphatic vessels
    • RELIGA P, CAO R, BJORNDAHL M, ZHOU Z, ZHU Z, CAO Y (2005). Presence of bone marrow-derived circulating progenitor endothelial cells in the newly formed lymphatic vessels. Blood 106: 4184-4190.
    • (2005) Blood , vol.106 , pp. 4184-4190
    • Religa, P.1    Cao, R.2    Bjorndahl, M.3    Zhou, Z.4    Zhu, Z.5    Cao, Y.6
  • 103
    • 33645046619 scopus 로고    scopus 로고
    • Inhibition of VEGFR-3 activation with the antagonistic antibody more potently suppresses lymph node and distant metastases than inactivation of VEGFR-2
    • ROBERTS N, KLOOS B, CASSELLA M, PODGRABINSKA S, PERSAUD K, WU Y, PYTOWSKI B, SKOBE M (2006). Inhibition of VEGFR-3 activation with the antagonistic antibody more potently suppresses lymph node and distant metastases than inactivation of VEGFR-2. Cancer Res 66: 2650-2657.
    • (2006) Cancer Res , vol.66 , pp. 2650-2657
    • Roberts, N.1    Kloos, B.2    Cassella, M.3    Podgrabinska, S.4    Persaud, K.5    Wu, Y.6    Pytowski, B.7    Skobe, M.8
  • 105
    • 43749106257 scopus 로고    scopus 로고
    • P19/Arf and p53 suppress sentinel lymph node lymphangiogenesis and carcinoma metastasis
    • RUDDELL A, KELLY-SPRATT KS, FURUYA M, PARGHI SS, KEMP CJ (2008b). p19/Arf and p53 suppress sentinel lymph node lymphangiogenesis and carcinoma metastasis. Oncogene 27: 3145-3155.
    • (2008) Oncogene , vol.27 , pp. 3145-3155
    • Ruddell, A.1    Kelly-Spratt, K.S.2    Furuya, M.3    Parghi, S.S.4    Kemp, C.J.5
  • 106
    • 84981813798 scopus 로고
    • On the origin of the lymphatic system from the veins and the development of the lymph hearts and thoracic duct in the pig
    • SABIN FR (1902). On the origin of the lymphatic system from the veins and the development of the lymph hearts and thoracic duct in the pig. Am J Anat 1: 367-389.
    • (1902) Am J Anat , vol.1 , pp. 367-389
    • Sabin, F.R.1
  • 109
    • 58149521991 scopus 로고    scopus 로고
    • Differential effects of the vascular endothelial growth factor receptor inhibitor PTK787/ZK222584 on tumor angiogenesis and tumor lymphangiogenesis
    • SCHOMBER T, ZUMSTEG A, STRITTMATTER K, CRNIC I, ANTONIADIS H, LITTLEWOOD-EVANS A, WOOD J, CHRISTOFORI G (2009). Differential effects of the vascular endothelial growth factor receptor inhibitor PTK787/ZK222584 on tumor angiogenesis and tumor lymphangiogenesis. Mol Cancer Ther 8: 55-63.
    • (2009) Mol Cancer Ther , vol.8 , pp. 55-63
    • Schomber, T.1    Zumsteg, A.2    Strittmatter, K.3    Crnic, I.4    Antoniadis, H.5    Littlewood-Evans, A.6    Wood, J.7    Christofori, G.8
  • 110
    • 56049097901 scopus 로고    scopus 로고
    • Combination therapy with short interfering RNA vectors against VEGF-C and VEGF-A suppresses lymph node and lung metastasis in a mouse immunocompetent mammary cancer model
    • SHIBATA MA, MORIMOTO J, SHIBATA E, OTSUKI Y (2008). Combination therapy with short interfering RNA vectors against VEGF-C and VEGF-A suppresses lymph node and lung metastasis in a mouse immunocompetent mammary cancer model. Cancer Gene Ther 15: 776-786.
    • (2008) Cancer Gene Ther , vol.15 , pp. 776-786
    • Shibata, M.A.1    Morimoto, J.2    Shibata, E.3    Otsuki, Y.4
  • 112
    • 34249774277 scopus 로고    scopus 로고
    • Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling
    • SHIELDS JD, FLEURY ME, YONG C, TOMEI AA, RANDOLPH GJ, SWARTZ MA (2007b). Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell 11: 526-538.
    • (2007) Cancer Cell , vol.11 , pp. 526-538
    • Shields, J.D.1    Fleury, M.E.2    Yong, C.3    Tomei, A.A.4    Randolph, G.J.5    Swartz, M.A.6
  • 113
    • 33947393171 scopus 로고    scopus 로고
    • Abnormal recruitment of periendothelial cells to lymphatic capillaries in digestive organs of angiopoietin-2-deficient mice
    • SHIMODA H, BERNAS MJ, WITTE MH, GALE NW, YANCOPOULOS GD, KATO S (2007). Abnormal recruitment of periendothelial cells to lymphatic capillaries in digestive organs of angiopoietin-2-deficient mice. Cell Tissue Res 328: 329-337.
    • (2007) Cell Tissue Res , vol.328 , pp. 329-337
    • Shimoda, H.1    Bernas, M.J.2    Witte, M.H.3    Gale, N.W.4    Yancopoulos, G.D.5    Kato, S.6
  • 114
    • 31944443701 scopus 로고    scopus 로고
    • Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: A role for FGF signaling in lymphangiogenesis
    • SHIN JW, MIN M, LARRIEU-LAHARGUE F, CANRON X, KUNSTFELD R, NGUYEN L, HENDERSON JE, BIKFALVI A, DETMAR M, HONG YK (2006). Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis. Mol Biol Cell 17: 576-584.
    • (2006) Mol Biol Cell , vol.17 , pp. 576-584
    • Shin, J.W.1    Min, M.2    Larrieu-Lahargue, F.3    Canron, X.4    Kunstfeld, R.5    Nguyen, L.6    Henderson, J.E.7    Bikfalvi, A.8    Detmar, M.9    Hong, Y.K.10
  • 120
    • 0037431546 scopus 로고    scopus 로고
    • Overexpression of CCR7 mRNA in nonsmall cell lung cancer: Correlation with lymph node metastasis
    • TAKANAMI I (2003). Overexpression of CCR7 mRNA in nonsmall cell lung cancer: correlation with lymph node metastasis. Int J Cancer 105: 186-189.
    • (2003) Int J Cancer , vol.105 , pp. 186-189
    • Takanami, I.1
  • 121
    • 76749083490 scopus 로고    scopus 로고
    • Lymphangiogenesis: Molecular mechanisms and future promise
    • TAMMELA T, ALITALO K (2010). Lymphangiogenesis: Molecular mechanisms and future promise. Cell 140: 460-476.
    • (2010) Cell , vol.140 , pp. 460-476
    • Tammela, T.1    Alitalo, K.2
  • 126
    • 0033578853 scopus 로고    scopus 로고
    • Prox1 function is required for the development of the murine lymphatic system
    • WIGLE JT, OLIVER G (1999). Prox1 function is required for the development of the murine lymphatic system. Cell 98: 769-778.
    • (1999) Cell , vol.98 , pp. 769-778
    • Wigle, J.T.1    Oliver, G.2
  • 127
    • 0035824083 scopus 로고    scopus 로고
    • Expression of CC chemokine receptor-7 and regional lymph node metastasis of B16 murine melanoma
    • WILEY HE, GONZALEZ EB, MAKI W, WU MT, HWANG ST (2001). Expression of CC chemokine receptor-7 and regional lymph node metastasis of B16 murine melanoma. J Natl Cancer Inst 93: 1638-1643.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1638-1643
    • Wiley, H.E.1    Gonzalez, E.B.2    Maki, W.3    Wu, M.T.4    Hwang, S.T.5
  • 129
    • 77951651923 scopus 로고    scopus 로고
    • Development and characterization of a novel method for the analysis of gene expression patterns in lymphatic endothelial cells derived from primary breast tissues
    • WU M, HAN L, SHI Y, XU G, WEI J, YOU L, CHEN Y, ZHU T, LI Q, LI S, MENG L, LU Y, ZHOU J, WANG S, MA D (2010). Development and characterization of a novel method for the analysis of gene expression patterns in lymphatic endothelial cells derived from primary breast tissues. J Cancer Res Clin Oncol 136: 863-872.
    • (2010) J Cancer Res Clin Oncol , vol.136 , pp. 863-872
    • Wu, M.1    Han, L.2    Shi, Y.3    Xu, G.4    Wei, J.5    You, L.6    Chen, Y.7    Zhu, T.8    Li, Q.9    Li, S.10    Meng, L.11    Lu, Y.12    Zhou, J.13    Wang, S.14    Ma, D.15
  • 131
    • 61449109981 scopus 로고    scopus 로고
    • COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction
    • YAMAZAKI T, YOSHIMATSU Y, MORISHITA Y, MIYAZONO K, WATABE T (2009). COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction. Genes Cells 14: 425-434.
    • (2009) Genes Cells , vol.14 , pp. 425-434
    • Yamazaki, T.1    Yoshimatsu, Y.2    Morishita, Y.3    Miyazono, K.4    Watabe, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.