Deletion of peptide amidation enzymatic activity leads to edema and embryonic lethality in the mouse

Developmental Biology

Volumn 287, Issue 2, 2005, Pages 301-313

  Czyzyk, Traci A ^a,c   Ning, Yun ^a   Hsu, Ming Sing ^a   Peng, Bonnie ^a   Mains, Richard E ^b   Eipper, Betty A ^b   Pintar, John E ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Adrenomedullin; Cardiovascular; Edema; Glucose tolerance test; Knockout mouse; PACAP; PAM; Peptide amidation

Indexed keywords

ADRENOMEDULLIN; ALPHA AMIDATING ENZYME; PEPTIDE HORMONE;

ALLELE; AMIDATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA; ARTERY DISEASE; ARTICLE; CARDIOVASCULAR DISEASE; CAROTID ARTERY; CATALYSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DELETION MUTANT; EDEMA; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; FEMALE; GENE FUNCTION; GLUCOSE INTOLERANCE; HETEROZYGOSITY; MALE; MOLECULAR DYNAMICS; MOUSE; NEUROBLAST; NONHUMAN; OBESITY; PERIKARYON; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; TERMINAL SEQUENCE;

ANIMALIA; RODENTIA;

EID: 27744573043     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2005.09.001     Document Type: Article

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