Disruption of Bcr-Abl coiled coil oligomerization by design

Journal of Biological Chemistry

Volumn 286, Issue 31, 2011, Pages 27751-27760

  Dixon, Andrew S ^a   Pendley, Scott S ^a   Bruno, Benjamin J ^a   Woessner, David W ^a   Shimpi, Adrian A ^b   Cheatham III, Thomas E ^a   Lim, Carol S ^a  

^a UNIVERSITY OF UTAH   (United States)

^b Juan Diego Catholic High School   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE-3; CHARGE-CHARGE REPULSION; COILED COIL; COILED-COIL DOMAINS; IN-VITRO; K562 CELLS; KINASE ACTIVITY; OLIGOMERIC STATE; ONCOPROTEINS; OPTIMAL MUTATION; PATHOGENIC PROTEINS; REGULATORY MECHANISM; SALT BRIDGES; SMALL MOLECULE INHIBITOR; THERAPEUTIC INTERVENTION; WILD TYPES;

CELL PROLIFERATION; OLIGOMERIZATION; OPTIMIZATION; PHOSPHORYLATION;

OLIGOMERS;

BCR ABL PROTEIN; CASPASE 3; CASPASE 7; PHOSPHOTRANSFERASE;

ARTICLE; CELL PROLIFERATION; CELL STRAIN COS7; CELL STRAIN K 562; COILED COIL DOMAIN; COMPUTER MODEL; COMPUTER SIMULATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; GENE MUTATION; INHIBITION KINETICS; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; WILD TYPE;

ANIMALS; BIOPOLYMERS; BLOTTING, WESTERN; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; COMPUTER SIMULATION; COS CELLS; FUSION PROTEINS, BCR-ABL; HUMANS; HYDROGEN BONDING; K562 CELLS; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MUTAGENESIS; PLASMIDS; PROTEIN BINDING; THERMODYNAMICS; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 79961002781     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.264903     Document Type: Article

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