Converging Free Energy Estimates: MM-PB(GB)SA Studies on the Protein-Protein Complex Ras-Raf

Journal of Computational Chemistry

Volumn 25, Issue 2, 2004, Pages 238-250

  Gohlke, Holger ^a   Case, David A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Absolute binding free energy; Entropy; Generalized Born model; Protein protein interactions; Ras

Indexed keywords

ABSOLUTE BINDING FREE ENERGY; GENERALIZED BORN MODEL; MUTATIONS; PROTEIN-PROTEIN INTERACTIONS;

ANTIBODIES; COMPUTER SIMULATION; ENTROPY; ENZYMES; HORMONES; MOLECULAR BIOLOGY; POISSON EQUATION; VAN DER WAALS FORCES;

FREE ENERGY;

RAB PROTEIN; RAS PROTEIN; SOLVENT;

ARTICLE; CALORIMETRY; CHEMISTRY; COMPUTER SIMULATION; ENTROPY; SOLUTION AND SOLUBILITY; THERMODYNAMICS;

CALORIMETRY; COMPUTER SIMULATION; ENTROPY; RAB GTP-BINDING PROTEINS; RAS PROTEINS; SOLUTIONS; SOLVENTS; THERMODYNAMICS;

EID: 0347602124     PISSN: 01928651     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcc.10379     Document Type: Article

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