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Volumn 47, Issue 9, 1999, Pages 1101-1109

Cytochemical methods for the detection of apoptosis

Author keywords

Annexin V; Apoptosis; Blebbing; Caspases; Cell death; DNA cytochemistry; DNA fragmentation; In situ end labeling; ISEL; ISNT; Mitochondria; Time lapse microscopy; TUNEL

Indexed keywords

APOPTOSIS; CELL DEATH; CELL STRUCTURE; CELL SURFACE; CYTOCHEMISTRY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DNA STRAND BREAKAGE; IN SITU HYBRIDIZATION; MICROSCOPY; NOMENCLATURE; PRIORITY JOURNAL; REVIEW;

EID: 0032870081     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549904700901     Document Type: Review
Times cited : (283)

References (54)
  • 1
    • 0030757751 scopus 로고    scopus 로고
    • Morphological and biochemical characterization and analysis of apoptosis
    • Allen RT, Hunter WJ, Agrawal DK (1997) Morphological and biochemical characterization and analysis of apoptosis. J Pharmacol Toxicol Methods 37:215-228
    • (1997) J Pharmacol Toxicol Methods , vol.37 , pp. 215-228
    • Allen, R.T.1    Hunter, W.J.2    Agrawal, D.K.3
  • 2
    • 0027191429 scopus 로고
    • In situ end labeling detects DNA strand breaks in apoptosis and other physiological and pathological states
    • Ansari B, Coates BD, Greenstein BD, Hall PA (1993) In situ end labeling detects DNA strand breaks in apoptosis and other physiological and pathological states. J Pathol 170:1-8
    • (1993) J Pathol , vol.170 , pp. 1-8
    • Ansari, B.1    Coates, B.D.2    Greenstein, B.D.3    Hall, P.A.4
  • 3
    • 0030015307 scopus 로고    scopus 로고
    • Quantification of apoptotic cells with fluorescein isothiocyanate-labeled annexin V in Chinese hamster ovary cell cultures treated with cisplatin
    • Boersma AW, Nooter K, Oostrum RG, Stoter G (1996) Quantification of apoptotic cells with fluorescein isothiocyanate-labeled annexin V in Chinese hamster ovary cell cultures treated with cisplatin. Cytometry 24:123-130
    • (1996) Cytometry , vol.24 , pp. 123-130
    • Boersma, A.W.1    Nooter, K.2    Oostrum, R.G.3    Stoter, G.4
  • 5
    • 85038141392 scopus 로고    scopus 로고
    • Induction of apoptosis by gemcitabine in BG-1 human ovarian cancer cells compared with induction by staurosporine, paclitaxel and cisplatin
    • (in press)
    • Cartee L, Kucera GL, Willingham MC (in press) Induction of apoptosis by gemcitabine in BG-1 human ovarian cancer cells compared with induction by staurosporine, paclitaxel and cisplatin. Apoptosis
    • Apoptosis
    • Cartee, L.1    Kucera, G.L.2    Willingham, M.C.3
  • 9
    • 0031922060 scopus 로고    scopus 로고
    • Biotin-labeled hairpin oligonucleotides: Probes to detect double-strand breaks in DNA in apoptotic cells
    • Didenko W, Tunstead JR, Hornsby PJ (1998) Biotin-labeled hairpin oligonucleotides: probes to detect double-strand breaks in DNA in apoptotic cells. Am J Pathol 152:897-902
    • (1998) Am J Pathol , vol.152 , pp. 897-902
    • Didenko, W.1    Tunstead, J.R.2    Hornsby, P.J.3
  • 13
    • 0030219916 scopus 로고    scopus 로고
    • Monoclonal antibody to a single-stranded DNA is a specific and sensitive cellular marker of apoptosis
    • Frankfurt OS, Robb JA, Sugarbaker EV, Villa L (1996a) Monoclonal antibody to a single-stranded DNA is a specific and sensitive cellular marker of apoptosis. Exp Cell Res 226:387-397
    • (1996) Exp Cell Res , vol.226 , pp. 387-397
    • Frankfurt, O.S.1    Robb, J.A.2    Sugarbaker, E.V.3    Villa, L.4
  • 14
    • 0029783628 scopus 로고    scopus 로고
    • Apoptosis in human breast and gastrointestinal carcinomas. Detection in histological sections with monoclonal antibody to single-stranded DNA
    • Frankfurt OS, Robb JA, Sugarbaker EV, Villa L (1996b) Apoptosis in human breast and gastrointestinal carcinomas. Detection in histological sections with monoclonal antibody to single-stranded DNA. Anticancer Res 16:1979-1988
    • (1996) Anticancer Res , vol.16 , pp. 1979-1988
    • Frankfurt, O.S.1    Robb, J.A.2    Sugarbaker, E.V.3    Villa, L.4
  • 15
    • 0031422897 scopus 로고    scopus 로고
    • Quantitative comparison of in situ methods for detecting apoptosis induced by X-ray irradiation in mouse thymus
    • Fujita K, Ohyama H, Yamada T (1997) Quantitative comparison of in situ methods for detecting apoptosis induced by X-ray irradiation in mouse thymus. Histochem J 29:823-830
    • (1997) Histochem J , vol.29 , pp. 823-830
    • Fujita, K.1    Ohyama, H.2    Yamada, T.3
  • 16
    • 0031855798 scopus 로고    scopus 로고
    • Comparison of annexin V and calcein-AM as early vital markers of apoptosis in adherent cells by confocal laser microscopy
    • Gatti R, Belletti S, Orlandini G, Bussolati O, Dall'Asta V, Gazzola GC (1998) Comparison of annexin V and calcein-AM as early vital markers of apoptosis in adherent cells by confocal laser microscopy. J Histochem Cytochem 46:895-900
    • (1998) J Histochem Cytochem , vol.46 , pp. 895-900
    • Gatti, R.1    Belletti, S.2    Orlandini, G.3    Bussolati, O.4    Dall'Asta, V.5    Gazzola, G.C.6
  • 17
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493-501
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 18
    • 0028589378 scopus 로고
    • Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis
    • Hall PA, Coates PJ, Ansari B, Hopwood D (1994) Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis. J Cell Sci 107:3569-3577
    • (1994) J Cell Sci , vol.107 , pp. 3569-3577
    • Hall, P.A.1    Coates, P.J.2    Ansari, B.3    Hopwood, D.4
  • 19
    • 0030763234 scopus 로고    scopus 로고
    • Separation of germ cell apoptosis from toxin-induced cell death by necrosis using in situ end-labeling histochemistry after glutaraldehyde fixation
    • Hikim AO, Lue Y, Swerdloff RS (1997) Separation of germ cell apoptosis from toxin-induced cell death by necrosis using in situ end-labeling histochemistry after glutaraldehyde fixation. Tissue Cell 29:487-493
    • (1997) Tissue Cell , vol.29 , pp. 487-493
    • Hikim, A.O.1    Lue, Y.2    Swerdloff, R.S.3
  • 20
    • 0033596909 scopus 로고    scopus 로고
    • A conformational change in cytochrome c of apoptotic and necrotic cells is detected by monoclonal antibody binding and mimicked by association of the native antigen with synthetic phospholipid vesicles
    • Jemmerson R, Liu J, Hausauer D, Kong-Peng L, Mondino A, Nelson RD (1999) A conformational change in cytochrome c of apoptotic and necrotic cells is detected by monoclonal antibody binding and mimicked by association of the native antigen with synthetic phospholipid vesicles. Biochemistry 38:3599-3609
    • (1999) Biochemistry , vol.38 , pp. 3599-3609
    • Jemmerson, R.1    Liu, J.2    Hausauer, D.3    Kong-Peng, L.4    Mondino, A.5    Nelson, R.D.6
  • 21
    • 0031001008 scopus 로고    scopus 로고
    • Immunohistochemical study on tissue transglutaminase and copper-zinc superoxide dismutase in human myocardium: Its relevance to apoptosis detected by the nick end labelling method
    • Kashima K, Yokoyama S, Daa T, Nakayama I, Iwaki T (1997) Immunohistochemical study on tissue transglutaminase and copper-zinc superoxide dismutase in human myocardium: its relevance to apoptosis detected by the nick end labelling method. Virchows Arch 430:333-338
    • (1997) Virchows Arch , vol.430 , pp. 333-338
    • Kashima, K.1    Yokoyama, S.2    Daa, T.3    Nakayama, I.4    Iwaki, T.5
  • 22
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JFR, Wyllie AH, Currie AR (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 23
    • 0031922432 scopus 로고    scopus 로고
    • RNA synthesis and splicing interferes with DNA in situ end labeling techniques used to detect apoptosis
    • Kockx MM, Muhring J, Knaapen MWM, deMeyer GRY (1998) RNA synthesis and splicing interferes with DNA in situ end labeling techniques used to detect apoptosis. Am J Pathol 152: 885-888
    • (1998) Am J Pathol , vol.152 , pp. 885-888
    • Kockx, M.M.1    Muhring, J.2    Knaapen, M.W.M.3    DeMeyer, G.R.Y.4
  • 24
    • 0031434775 scopus 로고    scopus 로고
    • Monitoring early cellular responses in apoptosis is aided by the mitochondrial membrane protein-specific monoclonal antibody APO2.7
    • Koester SK, Roth P, Mikulka WR, Schlossman SF, Zhang C, Bolton WE (1997) Monitoring early cellular responses in apoptosis is aided by the mitochondrial membrane protein-specific monoclonal antibody APO2.7. Cytometry 29:306-312
    • (1997) Cytometry , vol.29 , pp. 306-312
    • Koester, S.K.1    Roth, P.2    Mikulka, W.R.3    Schlossman, S.F.4    Zhang, C.5    Bolton, W.E.6
  • 25
    • 0027989808 scopus 로고
    • Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis
    • Koopman G, Reutelingsperger CP, Kuijten GA, Keehnen RM, Pasla ST, van Oers MH (1994) Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84:1415-1420
    • (1994) Blood , vol.84 , pp. 1415-1420
    • Koopman, G.1    Reutelingsperger, C.P.2    Kuijten, G.A.3    Keehnen, R.M.4    Pasla, S.T.5    Van Oers, M.H.6
  • 27
    • 0029891890 scopus 로고    scopus 로고
    • Bleb formation and f-actin distribution during mitosis and tumor necrosis factor-induced apoptosis
    • Laster SM, Mackenzie JM (1996) Bleb formation and F-actin distribution during mitosis and tumor necrosis factor-induced apoptosis. Microsc Res Tech 34:272-280
    • (1996) Microsc Res Tech , vol.34 , pp. 272-280
    • Laster, S.M.1    Mackenzie, J.M.2
  • 28
    • 0031440380 scopus 로고    scopus 로고
    • Strategies for phenotyping apoptotic peripheral human lymphocytes comparing ISNT, annexin-V and 7-AAD cytofluorometric staining methods
    • Lecoeur H, Ledru E, Prevost MC, Pougeon ML (1997) Strategies for phenotyping apoptotic peripheral human lymphocytes comparing ISNT, annexin-V and 7-AAD cytofluorometric staining methods. J Immunol Methods 209:111-123
    • (1997) J Immunol Methods , vol.209 , pp. 111-123
    • Lecoeur, H.1    Ledru, E.2    Prevost, M.C.3    Pougeon, M.L.4
  • 30
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
    • Martin SJ, Reutelingsperger CP, McGahon AJ, Rader JA, van Schie RC, LaFace DM, Green DR (1995) Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J Exp Med 182:1545-1556
    • (1995) J Exp Med , vol.182 , pp. 1545-1556
    • Martin, S.J.1    Reutelingsperger, C.P.2    McGahon, A.J.3    Rader, J.A.4    Van Schie, R.C.5    LaFace, D.M.6    Green, D.R.7
  • 32
    • 0014861959 scopus 로고
    • Terminal lens cell differentiation
    • Modak SP, Bollum FJ (1970) Terminal lens cell differentiation. Exp Cell Res 62:421-432
    • (1970) Exp Cell Res , vol.62 , pp. 421-432
    • Modak, S.P.1    Bollum, F.J.2
  • 33
    • 0015452611 scopus 로고
    • Detection and measurement of single-stranded breaks in nuclear DNA in fixed lens sections
    • Modak SP, Bollum FJ (1972) Detection and measurement of single-stranded breaks in nuclear DNA in fixed lens sections. Exp Cell Res 75:307-313
    • (1972) Exp Cell Res , vol.75 , pp. 307-313
    • Modak, S.P.1    Bollum, F.J.2
  • 35
    • 0028219709 scopus 로고
    • Antibody against single-stranded DNA detects both programmed cell death and drug-induced apoptosis
    • Naruse I, Keino H, Kawarada Y (1994) Antibody against single-stranded DNA detects both programmed cell death and drug-induced apoptosis. Histochemistry 101:73-78
    • (1994) Histochemistry , vol.101 , pp. 73-78
    • Naruse, I.1    Keino, H.2    Kawarada, Y.3
  • 37
    • 0030966323 scopus 로고    scopus 로고
    • Annexin-V and TUNEL used in monitoring the progression of apoptosis in plants
    • O'Brien IE, Reutelingsperger CP, Holdaway KM (1997) Annexin-V and TUNEL used in monitoring the progression of apoptosis in plants. Cytometry 29:28-33
    • (1997) Cytometry , vol.29 , pp. 28-33
    • O'Brien, I.E.1    Reutelingsperger, C.P.2    Holdaway, K.M.3
  • 38
    • 0029883542 scopus 로고    scopus 로고
    • Paclitaxel-induced apoptotic changes followed by time-lapse video microscopy in cell lines established from head and neck cancer
    • Pulkkinen JO, Elomaa L, Joensuu H, Martikainen P, Servomaa K, Grenman R (1996) Paclitaxel-induced apoptotic changes followed by time-lapse video microscopy in cell lines established from head and neck cancer. J Cancer Res Clin Oncol 122:214-218
    • (1996) J Cancer Res Clin Oncol , vol.122 , pp. 214-218
    • Pulkkinen, J.O.1    Elomaa, L.2    Joensuu, H.3    Martikainen, P.4    Servomaa, K.5    Grenman, R.6
  • 39
    • 0031007673 scopus 로고    scopus 로고
    • Increased surface phosphatidylserine is an early marker of neuronal apoptosis
    • Rimon G, Bazenet CE, Philpott KL, Rubin LL (1997) Increased surface phosphatidylserine is an early marker of neuronal apoptosis. J Neurosci Res 48:563-570
    • (1997) J Neurosci Res , vol.48 , pp. 563-570
    • Rimon, G.1    Bazenet, C.E.2    Philpott, K.L.3    Rubin, L.L.4
  • 40
    • 0030771250 scopus 로고    scopus 로고
    • Methods for detecting apoptotic cells in tissues
    • Sanders EJ (1997) Methods for detecting apoptotic cells in tissues. Histol Histopathol 12:1169-1177
    • (1997) Histol Histopathol , vol.12 , pp. 1169-1177
    • Sanders, E.J.1
  • 41
    • 0027994239 scopus 로고
    • Cell nucleus and DNA fragmentation are not required for apoptosis
    • Schulze-Osthoff K, Walczak H, Droge W, Krammer PH (1994) Cell nucleus and DNA fragmentation are not required for apoptosis. J Cell Biol 127:15-20
    • (1994) J Cell Biol , vol.127 , pp. 15-20
    • Schulze-Osthoff, K.1    Walczak, H.2    Droge, W.3    Krammer, P.H.4
  • 43
    • 0031918971 scopus 로고    scopus 로고
    • Effects of prefixation and fixation times on apoptosis detection by in situ end-labeling of fragmented DNA
    • Tateyama H, Tada T, Hattori H, Murase T, Li W-X, Eimoto T (1998) Effects of prefixation and fixation times on apoptosis detection by in situ end-labeling of fragmented DNA. Arch Pathol Lab Med 122:252-255
    • (1998) Arch Pathol Lab Med , vol.122 , pp. 252-255
    • Tateyama, H.1    Tada, T.2    Hattori, H.3    Murase, T.4    Li, W.-X.5    Eimoto, T.6
  • 44
    • 0031696403 scopus 로고    scopus 로고
    • A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease
    • Tatton NA, Maclean-Fraser A, Tatton WG, Perl DP, Olanow CW (1998) A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease. Ann Neurol 44: S142-148
    • (1998) Ann Neurol , vol.44
    • Tatton, N.A.1    Maclean-Fraser, A.2    Tatton, W.G.3    Perl, D.P.4    Olanow, C.W.5
  • 46
    • 0031985647 scopus 로고    scopus 로고
    • Annexin V-affinity assay: A review on an apoptosis detection system based on phosphatidylserine exposure
    • van Engeland M, Nieland LJ, Ramaekers FC, Schutte B, Reutelingsperger CP (1998) Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure. Cytometry 31:1-9
    • (1998) Cytometry , vol.31 , pp. 1-9
    • Van Engeland, M.1    Nieland, L.J.2    Ramaekers, F.C.3    Schutte, B.4    Reutelingsperger, C.P.5
  • 47
    • 0033593791 scopus 로고    scopus 로고
    • Altered cytochrome c display precedes apoptotic cell death in Drosophila
    • Varkey J, Chen P, Jemmerson R, Abrams JM (1999) Altered cytochrome c display precedes apoptotic cell death in Drosophila. J Cell Biol 144:701-710
    • (1999) J Cell Biol , vol.144 , pp. 701-710
    • Varkey, J.1    Chen, P.2    Jemmerson, R.3    Abrams, J.M.4
  • 48
    • 0026670335 scopus 로고
    • Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: An overview
    • Wyllie AH (1992) Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview. Cancer Metast Rev 11:95-103
    • (1992) Cancer Metast Rev , vol.11 , pp. 95-103
    • Wyllie, A.H.1
  • 51
    • 0031930313 scopus 로고    scopus 로고
    • Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease
    • Yang F, Sun X, Beech W, Teter B, Wu S, Sigel J, Vinters HV, Frautschy SA, Cole GM (1998) Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease. Am J Pathol 152:379-389
    • (1998) Am J Pathol , vol.152 , pp. 379-389
    • Yang, F.1    Sun, X.2    Beech, W.3    Teter, B.4    Wu, S.5    Sigel, J.6    Vinters, H.V.7    Frautschy, S.A.8    Cole, G.M.9
  • 52
    • 0030294374 scopus 로고    scopus 로고
    • A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells
    • Zhang C, Ao Z, Seth A, Schlossman SF (1996) A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells. J Immunol 157:3980-3987
    • (1996) J Immunol , vol.157 , pp. 3980-3987
    • Zhang, C.1    Ao, Z.2    Seth, A.3    Schlossman, S.F.4
  • 53
    • 0030883765 scopus 로고    scopus 로고
    • Early detection of apoptosis using a fluorescent conjugate of annexin V
    • Zhang G, Gurtu V, Kain SR, Yan G (1997) Early detection of apoptosis using a fluorescent conjugate of annexin V. Biotechniques 23:525-531
    • (1997) Biotechniques , vol.23 , pp. 525-531
    • Zhang, G.1    Gurtu, V.2    Kain, S.R.3    Yan, G.4


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