메뉴 건너뛰기




Volumn 35, Issue 5, 2011, Pages 768-789

Metabolic regulation of antibiotic resistance

Author keywords

Bacterial metabolism; Biofilm; Fitness cost; Global regulation; Persister; Signal transduction

Indexed keywords

AMINOGLYCOSIDE; AMPICILLIN; ANTIBIOTIC AGENT; BACTERIAL PROTEIN; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CARBON; CBRA PROTEIN; CHLORAMPHENICOL; CIPROFLOXACIN; FOSFOMYCIN; IMIPENEM; ISONIAZID; METRONIDAZOLE; OUTER MEMBRANE PROTEIN C; OUTER MEMBRANE PROTEIN F; PENICILLIN BINDING PROTEIN; PENICILLIN G; POLYMYXIN; QUINOLONE DERIVATIVE; RNA BINDING PROTEIN; STREPTOMYCIN; TETRACYCLINE; TOBRAMYCIN; TUBERCULOSTATIC AGENT; TUNICAMYCIN; UNCLASSIFIED DRUG;

EID: 79960939536     PISSN: 01686445     EISSN: 15746976     Source Type: Journal    
DOI: 10.1111/j.1574-6976.2011.00282.x     Document Type: Review
Times cited : (214)

References (235)
  • 1
    • 64049116097 scopus 로고    scopus 로고
    • The molecular alarmone (p)ppGpp mediates stress responses, vancomycin tolerance, and virulence in Enterococcus faecalis
    • Abranches J, Martinez AR, Kajfasz JK, Chavez V, Garsin DA & Lemos JA (2009) The molecular alarmone (p)ppGpp mediates stress responses, vancomycin tolerance, and virulence in Enterococcus faecalis. J Bacteriol 191: 2248-2256.
    • (2009) J Bacteriol , vol.191 , pp. 2248-2256
    • Abranches, J.1    Martinez, A.R.2    Kajfasz, J.K.3    Chavez, V.4    Garsin, D.A.5    Lemos, J.A.6
  • 2
    • 0036667424 scopus 로고    scopus 로고
    • Characterization of a new efflux pump, MexGHI-OpmD, from Pseudomonas aeruginosa that confers resistance to vanadium
    • Aendekerk S, Ghysels B, Cornelis P & Baysse C (2002) Characterization of a new efflux pump, MexGHI-OpmD, from Pseudomonas aeruginosa that confers resistance to vanadium. Microbiology 148: 2371-2381.
    • (2002) Microbiology , vol.148 , pp. 2371-2381
    • Aendekerk, S.1    Ghysels, B.2    Cornelis, P.3    Baysse, C.4
  • 3
    • 17644369248 scopus 로고    scopus 로고
    • The MexGHI-OpmD multidrug efflux pump controls growth, antibiotic susceptibility and virulence in Pseudomonas aeruginosa via 4-quinolone-dependent cell-to-cell communication
    • Aendekerk S, Diggle SP, Song Z, Hoiby N, Cornelis P, Williams P & Camara M (2005) The MexGHI-OpmD multidrug efflux pump controls growth, antibiotic susceptibility and virulence in Pseudomonas aeruginosa via 4-quinolone-dependent cell-to-cell communication. Microbiology 151: 1113-1125.
    • (2005) Microbiology , vol.151 , pp. 1113-1125
    • Aendekerk, S.1    Diggle, S.P.2    Song, Z.3    Hoiby, N.4    Cornelis, P.5    Williams, P.6    Camara, M.7
  • 4
    • 0000148162 scopus 로고    scopus 로고
    • Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon
    • Alekshun MN & Levy SB (1997) Regulation of chromosomally mediated multiple antibiotic resistance: the mar regulon. Antimicrob Agents Ch 41: 2067-2075.
    • (1997) Antimicrob Agents Ch - , vol.41 , pp. 2067-2075
    • Alekshun, M.N.1    Levy, S.B.2
  • 5
    • 33947260230 scopus 로고    scopus 로고
    • Molecular mechanisms of antibacterial multidrug resistance
    • Alekshun MN & Levy SB (2007) Molecular mechanisms of antibacterial multidrug resistance. Cell 128: 1037-1050.
    • (2007) Cell , vol.128 , pp. 1037-1050
    • Alekshun, M.N.1    Levy, S.B.2
  • 6
    • 79955886933 scopus 로고    scopus 로고
    • Metabolite-enabled eradication of bacterial persisters by aminoglycosides
    • Allison KR, Brynildsen MP & Collins JJ (2011) Metabolite-enabled eradication of bacterial persisters by aminoglycosides. Nature 473: 216-220.
    • (2011) Nature , vol.473 , pp. 216-220
    • Allison, K.R.1    Brynildsen, M.P.2    Collins, J.J.3
  • 7
    • 0343683417 scopus 로고    scopus 로고
    • Multiple antibiotic resistance in Stenotrophomonas maltophilia
    • Alonso A & Martinez JL (1997) Multiple antibiotic resistance in Stenotrophomonas maltophilia. Antimicrob Agents Ch 41: 1140-1142.
    • (1997) Antimicrob Agents Ch , vol.41 , pp. 1140-1142
    • Alonso, A.1    Martinez, J.L.2
  • 8
    • 0033734699 scopus 로고    scopus 로고
    • Cloning and characterization of SmeDEF, a novel multidrug efflux pump from Stenotrophomonas maltophilia
    • Alonso A & Martinez JL (2000) Cloning and characterization of SmeDEF, a novel multidrug efflux pump from Stenotrophomonas maltophilia. Antimicrob Agents Ch 44: 3079-3086.
    • (2000) Antimicrob Agents Ch , vol.44 , pp. 3079-3086
    • Alonso, A.1    Martinez, J.L.2
  • 9
    • 0035010671 scopus 로고    scopus 로고
    • Expression of multidrug efflux pump SmeDEF by clinical isolates of Stenotrophomonas maltophilia
    • Alonso A & Martinez JL (2001) Expression of multidrug efflux pump SmeDEF by clinical isolates of Stenotrophomonas maltophilia. Antimicrob Agents Ch 45: 1879-1881.
    • (2001) Antimicrob Agents Ch , vol.45 , pp. 1879-1881
    • Alonso, A.1    Martinez, J.L.2
  • 10
    • 0033207021 scopus 로고    scopus 로고
    • Environmental and clinical isolates of Pseudomonas aeruginosa show pathogenic and biodegradative properties irrespective of their origin
    • Alonso A, Rojo F & Martinez JL (1999) Environmental and clinical isolates of Pseudomonas aeruginosa show pathogenic and biodegradative properties irrespective of their origin. Environ Microbiol 1: 421-430.
    • (1999) Environ Microbiol , vol.1 , pp. 421-430
    • Alonso, A.1    Rojo, F.2    Martinez, J.L.3
  • 12
    • 71249091793 scopus 로고    scopus 로고
    • The role of antibiotics and antibiotic resistance in nature
    • Aminov RI (2009) The role of antibiotics and antibiotic resistance in nature. Environ Microbiol 11: 2970-2988.
    • (2009) Environ Microbiol , vol.11 , pp. 2970-2988
    • Aminov, R.I.1
  • 13
    • 33748693294 scopus 로고    scopus 로고
    • The biological cost of mutational antibiotic resistance: any practical conclusions?
    • Andersson DI (2006) The biological cost of mutational antibiotic resistance: any practical conclusions? Curr Opin Microbiol 9: 461-465.
    • (2006) Curr Opin Microbiol - , vol.9 , pp. 461-465
    • Andersson, D.I.1
  • 14
    • 77949569493 scopus 로고    scopus 로고
    • Antibiotic resistance and its cost: is it possible to reverse resistance?
    • Andersson DI & Hughes D (2010) Antibiotic resistance and its cost: is it possible to reverse resistance? Nat Rev Microbiol 8: 260-271.
    • (2010) Nat Rev Microbiol - , vol.8 , pp. 260-271
    • Andersson, D.I.1    Hughes, D.2
  • 15
    • 0032870940 scopus 로고    scopus 로고
    • The biological cost of antibiotic resistance
    • Andersson DI & Levin BR (1999) The biological cost of antibiotic resistance. Curr Opin Microbiol 2: 489-493.
    • (1999) Curr Opin Microbiol , vol.2 , pp. 489-493
    • Andersson, D.I.1    Levin, B.R.2
  • 17
    • 40549112302 scopus 로고    scopus 로고
    • Fitness of Streptococcus pneumoniae fluoroquinolone-resistant strains with topoisomerase IV recombinant genes
    • Balsalobre L & de la Campa AG (2008) Fitness of Streptococcus pneumoniae fluoroquinolone-resistant strains with topoisomerase IV recombinant genes. Antimicrob Agents Ch 52: 822-830.
    • (2008) Antimicrob Agents Ch , vol.52 , pp. 822-830
    • Balsalobre, L.1    de la Campa, A.G.2
  • 19
    • 0029760688 scopus 로고    scopus 로고
    • The high amino-acid content of sputum from cystic fibrosis patients promotes growth of auxotrophic Pseudomonas aeruginosa
    • Barth AL & Pitt TL (1996) The high amino-acid content of sputum from cystic fibrosis patients promotes growth of auxotrophic Pseudomonas aeruginosa. J Med Microbiol 45: 110-119.
    • (1996) J Med Microbiol , vol.45 , pp. 110-119
    • Barth, A.L.1    Pitt, T.L.2
  • 20
    • 0038583506 scopus 로고    scopus 로고
    • Staphylococcus aureus menD and hemB mutants are as infective as the parent strains, but the menadione biosynthetic mutant persists within the kidney
    • Bates DM, von Eiff C, McNamara PJ, Peters G, Yeaman MR, Bayer AS & Proctor RA (2003) Staphylococcus aureus menD and hemB mutants are as infective as the parent strains, but the menadione biosynthetic mutant persists within the kidney. J Infect Dis 187: 1654-1661.
    • (2003) J Infect Dis , vol.187 , pp. 1654-1661
    • Bates, D.M.1    von Eiff, C.2    McNamara, P.J.3    Peters, G.4    Yeaman, M.R.5    Bayer, A.S.6    Proctor, R.A.7
  • 21
    • 63149156264 scopus 로고    scopus 로고
    • Modulation of cell wall structure and antimicrobial susceptibility by a Staphylococcus aureus eukaryote-like serine/threonine kinase and phosphatase
    • Beltramini AM, Mukhopadhyay CD & Pancholi V (2009) Modulation of cell wall structure and antimicrobial susceptibility by a Staphylococcus aureus eukaryote-like serine/threonine kinase and phosphatase. Infect Immun 77: 1406-1416.
    • (2009) Infect Immun , vol.77 , pp. 1406-1416
    • Beltramini, A.M.1    Mukhopadhyay, C.D.2    Pancholi, V.3
  • 22
    • 0242711908 scopus 로고
    • Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria
    • Benveniste R & Davies J (1973) Aminoglycoside antibiotic-inactivating enzymes in actinomycetes similar to those present in clinical isolates of antibiotic-resistant bacteria. P Natl Acad Sci USA 70: 2276-2280.
    • (1973) P Natl Acad Sci USA , vol.70 , pp. 2276-2280
    • Benveniste, R.1    Davies, J.2
  • 23
    • 0035083932 scopus 로고    scopus 로고
    • H-NS and H-NS-like proteins in Gram-negative bacteria and their multiple role in the regulation of bacterial metabolism
    • Bertin P, Hommais F, Krin E, Soutourina O, Tendeng C, Derzelle S & Danchin A (2001) H-NS and H-NS-like proteins in Gram-negative bacteria and their multiple role in the regulation of bacterial metabolism. Biochimie 83: 235-241.
    • (2001) Biochimie , vol.83 , pp. 235-241
    • Bertin, P.1    Hommais, F.2    Krin, E.3    Soutourina, O.4    Tendeng, C.5    Derzelle, S.6    Danchin, A.7
  • 24
    • 0042373060 scopus 로고    scopus 로고
    • Effects of environment on compensatory mutations to ameliorate costs of antibiotic resistance
    • Bjorkman J, Nagaev I, Berg OG, Hughes D & Andersson DI (2000) Effects of environment on compensatory mutations to ameliorate costs of antibiotic resistance. Science 287: 1479-1482.
    • (2000) Science , vol.287 , pp. 1479-1482
    • Bjorkman, J.1    Nagaev, I.2    Berg, O.G.3    Hughes, D.4    Andersson, D.I.5
  • 25
    • 57049167197 scopus 로고    scopus 로고
    • Complex ciprofloxacin resistome revealed by screening a Pseudomonas aeruginosa mutant library for altered susceptibility
    • Breidenstein EB, Khaira BK, Wiegand I, Overhage J & Hancock RE (2008) Complex ciprofloxacin resistome revealed by screening a Pseudomonas aeruginosa mutant library for altered susceptibility. Antimicrob Agents Ch 52: 4486-4491.
    • (2008) Antimicrob Agents Ch , vol.52 , pp. 4486-4491
    • Breidenstein, E.B.1    Khaira, B.K.2    Wiegand, I.3    Overhage, J.4    Hancock, R.E.5
  • 26
    • 0017644533 scopus 로고
    • Effects of membrane-energy mutations and cations on streptomycin and gentamicin accumulation by bacteria; a model for entry of streptomycin and gentamicin in susceptible and resistant bacteria
    • Bryan LE & Van Den Elzen HM (1977) Effects of membrane-energy mutations and cations on streptomycin and gentamicin accumulation by bacteria: a model for entry of streptomycin and gentamicin in susceptible and resistant bacteria. Antimicrob Agents Ch 12: 163-177.
    • (1977) Antimicrob Agents Ch - , vol.12 , pp. 163-177
    • Bryan, L.E.1    Van Den Elzen, H.M.2
  • 27
    • 3342927601 scopus 로고    scopus 로고
    • Dynamics of success and failure in phage and antibiotic therapy in experimental infections
    • Bull JJ, Levin BR, DeRouin T, Walker N & Bloch CA (2002) Dynamics of success and failure in phage and antibiotic therapy in experimental infections. BMC Microbiol 2: 35.
    • (2002) BMC Microbiol , vol.2 , pp. 35
    • Bull, J.J.1    Levin, B.R.2    DeRouin, T.3    Walker, N.4    Bloch, C.A.5
  • 28
    • 2342621395 scopus 로고    scopus 로고
    • NorM, an Erwinia amylovora multidrug efflux pump involved in in vitro competition with other epiphytic bacteria
    • Burse A, Weingart H & Ullrich MS (2004) NorM, an Erwinia amylovora multidrug efflux pump involved in in vitro competition with other epiphytic bacteria. Appl Environ Microb 70: 693-703.
    • (2004) Appl Environ Microb , vol.70 , pp. 693-703
    • Burse, A.1    Weingart, H.2    Ullrich, M.S.3
  • 29
    • 0037635296 scopus 로고    scopus 로고
    • Selection of small-colony variants of Salmonella enterica serovar typhimurium in nonphagocytic eucaryotic cells
    • Cano DA, Pucciarelli MG, Martinez-Moya M, Casadesus J & Garcia-del Portillo F (2003) Selection of small-colony variants of Salmonella enterica serovar typhimurium in nonphagocytic eucaryotic cells. Infect Immun 71: 3690-3698.
    • (2003) Infect Immun , vol.71 , pp. 3690-3698
    • Cano, D.A.1    Pucciarelli, M.G.2    Martinez-Moya, M.3    Casadesus, J.4    Garcia-del Portillo, F.5
  • 30
    • 70350457941 scopus 로고    scopus 로고
    • Glycerol-3-phosphate permease GlpT is the only fosfomycin transporter in Pseudomonas aeruginosa
    • Castaneda-Garcia A, Rodriguez-Rojas A, Guelfo JR & Blazquez J (2009) Glycerol-3-phosphate permease GlpT is the only fosfomycin transporter in Pseudomonas aeruginosa. J Bacteriol 191: 6968-6974.
    • (2009) J Bacteriol , vol.191 , pp. 6968-6974
    • Castaneda-Garcia, A.1    Rodriguez-Rojas, A.2    Guelfo, J.R.3    Blazquez, J.4
  • 31
    • 77957946456 scopus 로고    scopus 로고
    • Letting sleeping dos lie: does dormancy play a role in tuberculosis?
    • Chao MC & Rubin EJ (2010) Letting sleeping dos lie: does dormancy play a role in tuberculosis? Annu Rev Microbiol 64: 293-311.
    • (2010) Annu Rev Microbiol - , vol.64 , pp. 293-311
    • Chao, M.C.1    Rubin, E.J.2
  • 32
    • 33845370997 scopus 로고    scopus 로고
    • Analysis of the mechanisms of fluoroquinolone resistance in urinary tract pathogens
    • Chenia HY, Pillay B & Pillay D (2006) Analysis of the mechanisms of fluoroquinolone resistance in urinary tract pathogens. J Antimicrob Chemoth 58: 1274-1278.
    • (2006) J Antimicrob Chemoth , vol.58 , pp. 1274-1278
    • Chenia, H.Y.1    Pillay, B.2    Pillay, D.3
  • 34
    • 24644507805 scopus 로고    scopus 로고
    • Evidence of an intracellular reservoir in the nasal mucosa of patients with recurrent Staphylococcus aureus rhinosinusitis
    • Clement S, Vaudaux P, Francois P et al. (2005) Evidence of an intracellular reservoir in the nasal mucosa of patients with recurrent Staphylococcus aureus rhinosinusitis. J Infect Dis 192: 1023-1028.
    • (2005) J Infect Dis , vol.192 , pp. 1023-1028
    • Clement, S.1    Vaudaux, P.2    Francois, P.3
  • 35
    • 0032899044 scopus 로고    scopus 로고
    • CtaA of Staphylococcus aureus is required for starvation survival, recovery, and cytochrome biosynthesis
    • Clements MO, Watson SP, Poole RK & Foster SJ (1999) CtaA of Staphylococcus aureus is required for starvation survival, recovery, and cytochrome biosynthesis. J Bacteriol 181: 501-507.
    • (1999) J Bacteriol , vol.181 , pp. 501-507
    • Clements, M.O.1    Watson, S.P.2    Poole, R.K.3    Foster, S.J.4
  • 36
    • 0024400856 scopus 로고
    • Cross-resistance to fluoroquinolones in multiple-antibiotic-resistant (Mar) Escherichia coli selected by tetracycline or chloramphenicol: decreased drug accumulation associated with membrane changes in addition to OmpF reduction
    • Cohen SP, McMurry LM, Hooper DC, Wolfson JS & Levy SB (1989) Cross-resistance to fluoroquinolones in multiple-antibiotic-resistant (Mar) Escherichia coli selected by tetracycline or chloramphenicol: decreased drug accumulation associated with membrane changes in addition to OmpF reduction. Antimicrob Agents Ch 33: 1318-1325.
    • (1989) Antimicrob Agents Ch - , vol.33 , pp. 1318-1325
    • Cohen, S.P.1    McMurry, L.M.2    Hooper, D.C.3    Wolfson, J.S.4    Levy, S.B.5
  • 37
    • 0029843951 scopus 로고    scopus 로고
    • Catabolite repression control in the Pseudomonads
    • Collier DN, Hager PW & Phibbs PV Jr (1996) Catabolite repression control in the Pseudomonads. Res Microbiol 147: 551-561.
    • (1996) Res Microbiol , vol.147 , pp. 551-561
    • Collier, D.N.1    Hager, P.W.2    Phibbs Jr, P.V.3
  • 38
    • 0026779245 scopus 로고
    • Crystal structures explain functional properties of two E. coli porins
    • Cowan SW, Schirmer T, Rummel G et al. (1992) Crystal structures explain functional properties of two E. coli porins. Nature 358: 727-733.
    • (1992) Nature , vol.358 , pp. 727-733
    • Cowan, S.W.1    Schirmer, T.2    Rummel, G.3
  • 39
    • 0242636506 scopus 로고    scopus 로고
    • Survival of nonspecific porin-deficient mutants of Escherichia coli in black sea water
    • Darcan C, Ozkanca R & Flint KP (2003) Survival of nonspecific porin-deficient mutants of Escherichia coli in black sea water. Lett Appl Microbiol 37: 380-385.
    • (2003) Lett Appl Microbiol , vol.37 , pp. 380-385
    • Darcan, C.1    Ozkanca, R.2    Flint, K.P.3
  • 40
    • 34247333058 scopus 로고    scopus 로고
    • Growth phenotypes of Pseudomonas aeruginosalasR mutants adapted to the airways of cystic fibrosis patients
    • D'Argenio DA, Wu M, Hoffman LR et al. (2007) Growth phenotypes of Pseudomonas aeruginosalasR mutants adapted to the airways of cystic fibrosis patients. Mol Microbiol 64: 512-533.
    • (2007) Mol Microbiol , vol.64 , pp. 512-533
    • D'Argenio, D.A.1    Wu, M.2    Hoffman, L.R.3
  • 41
    • 32244443761 scopus 로고    scopus 로고
    • The serine/threonine kinase PknB of Mycobacterium tuberculosis phosphorylates PBPA, a penicillin-binding protein required for cell division
    • Dasgupta A, Datta P, Kundu M & Basu J (2006) The serine/threonine kinase PknB of Mycobacterium tuberculosis phosphorylates PBPA, a penicillin-binding protein required for cell division. Microbiology 152: 493-504.
    • (2006) Microbiology , vol.152 , pp. 493-504
    • Dasgupta, A.1    Datta, P.2    Kundu, M.3    Basu, J.4
  • 42
    • 0030633357 scopus 로고    scopus 로고
    • Origins, acquisition and dissemination of antibiotic resistance determinants
    • Davies JE (1997) Origins, acquisition and dissemination of antibiotic resistance determinants. Ciba F Symp 207: 15-27.
    • (1997) Ciba F Symp , vol.207 , pp. 15-27
    • Davies, J.E.1
  • 43
    • 64649088018 scopus 로고    scopus 로고
    • Outer membrane permeability and antibiotic resistance
    • Delcour AH (2009) Outer membrane permeability and antibiotic resistance. Biochim Biophys Acta 1794: 808-816.
    • (2009) Biochim Biophys Acta , vol.1794 , pp. 808-816
    • Delcour, A.H.1
  • 44
    • 67649401960 scopus 로고    scopus 로고
    • Transcriptome and functional analysis of the eukaryotic-type serine/threonine kinase PknB in Staphylococcus aureus
    • Donat S, Streker K, Schirmeister T et al. (2009) Transcriptome and functional analysis of the eukaryotic-type serine/threonine kinase PknB in Staphylococcus aureus. J Bacteriol 191: 4056-4069.
    • (2009) J Bacteriol , vol.191 , pp. 4056-4069
    • Donat, S.1    Streker, K.2    Schirmeister, T.3
  • 45
    • 67049109139 scopus 로고    scopus 로고
    • Genomewide identification of genetic determinants of antimicrobial drug resistance in Pseudomonas aeruginosa
    • Dotsch A, Becker T, Pommerenke C, Magnowska Z, Jansch L & Haussler S (2009) Genomewide identification of genetic determinants of antimicrobial drug resistance in Pseudomonas aeruginosa. Antimicrob Agents Ch 53: 2522-2531.
    • (2009) Antimicrob Agents Ch , vol.53 , pp. 2522-2531
    • Dotsch, A.1    Becker, T.2    Pommerenke, C.3    Magnowska, Z.4    Jansch, L.5    Haussler, S.6
  • 46
    • 62549121211 scopus 로고    scopus 로고
    • Molecular mechanisms disrupting porin expression in ertapenem-resistant Klebsiella and Enterobacter spp. clinical isolates from the UK
    • Doumith M, Ellington MJ, Livermore DM & Woodford N (2009) Molecular mechanisms disrupting porin expression in ertapenem-resistant Klebsiella and Enterobacter spp. clinical isolates from the UK. J Antimicrob Chemoth 63: 659-667.
    • (2009) J Antimicrob Chemoth , vol.63 , pp. 659-667
    • Doumith, M.1    Ellington, M.J.2    Livermore, D.M.3    Woodford, N.4
  • 47
    • 0006782265 scopus 로고
    • The effect of the size of the inoculum and the age of the infection on the curative dose of penicillin in experimental infections with streptococci, pneumococci, and Treponema pallidum
    • Eagle H (1949) The effect of the size of the inoculum and the age of the infection on the curative dose of penicillin in experimental infections with streptococci, pneumococci, and Treponema pallidum. J Exp Med 90: 595-607.
    • (1949) J Exp Med , vol.90 , pp. 595-607
    • Eagle, H.1
  • 48
    • 33748711686 scopus 로고    scopus 로고
    • Evidence of antibiotic resistance gene silencing in Escherichia coli
    • Enne VI, Delsol AA, Roe JM & Bennett PM (2006) Evidence of antibiotic resistance gene silencing in Escherichia coli. Antimicrob Agents Ch 50: 3003-3010.
    • (2006) Antimicrob Agents Ch , vol.50 , pp. 3003-3010
    • Enne, V.I.1    Delsol, A.A.2    Roe, J.M.3    Bennett, P.M.4
  • 49
    • 33748509721 scopus 로고    scopus 로고
    • H-NS controls metabolism and stress tolerance in Escherichia coli O157:H7 that influence mouse passage
    • Erol I, Jeong KC, Baumler DJ, Vykhodets B, Choi SH & Kaspar CW (2006) H-NS controls metabolism and stress tolerance in Escherichia coli O157:H7 that influence mouse passage. BMC Microbiol 6: 72.
    • (2006) BMC Microbiol , vol.6 , pp. 72
    • Erol, I.1    Jeong, K.C.2    Baumler, D.J.3    Vykhodets, B.4    Choi, S.H.5    Kaspar, C.W.6
  • 50
    • 0031661594 scopus 로고    scopus 로고
    • Influence of the MexAB-OprM multidrug efflux system on quorum sensing in Pseudomonas aeruginosa
    • Evans K, Passador L, Srikumar R, Tsang E, Nezezon J & Poole K (1998) Influence of the MexAB-OprM multidrug efflux system on quorum sensing in Pseudomonas aeruginosa. J Bacteriol 180: 5443-5447.
    • (1998) J Bacteriol , vol.180 , pp. 5443-5447
    • Evans, K.1    Passador, L.2    Srikumar, R.3    Tsang, E.4    Nezezon, J.5    Poole, K.6
  • 51
    • 42049120716 scopus 로고    scopus 로고
    • Antibiotics as signals that trigger specific bacterial responses
    • Fajardo A & Martinez JL (2008) Antibiotics as signals that trigger specific bacterial responses. Curr Opin Microbiol 11: 161-167.
    • (2008) Curr Opin Microbiol , vol.11 , pp. 161-167
    • Fajardo, A.1    Martinez, J.L.2
  • 52
    • 42049115532 scopus 로고    scopus 로고
    • The neglected intrinsic resistome of bacterial pathogens
    • Fajardo A, Martinez-Martin N, Mercadillo M et al. (2008) The neglected intrinsic resistome of bacterial pathogens. PLoS One 3: e1619.
    • (2008) PLoS One , vol.3
    • Fajardo, A.1    Martinez-Martin, N.2    Mercadillo, M.3
  • 53
    • 59649121412 scopus 로고    scopus 로고
    • Towards an ecological approach to antibiotics and antibiotic resistance genes
    • Fajardo A, Linares JF & Martinez JL (2009) Towards an ecological approach to antibiotics and antibiotic resistance genes. Clin Microbiol Infec 15 (suppl 1): 14-16.
    • (2009) Clin Microbiol Infec , vol.15 , Issue.SUPPL. 1 , pp. 14-16
    • Fajardo, A.1    Linares, J.F.2    Martinez, J.L.3
  • 55
    • 0030902203 scopus 로고    scopus 로고
    • Molecular DNA analysis for differentiation of persistence or relapse from recurrence in treatment failure of Streptococcus pyogenes pharyngitis
    • Fitoussi F, Cohen R, Brami G, Doit C, Brahimi N, de la Rocque F & Bingen E (1997) Molecular DNA analysis for differentiation of persistence or relapse from recurrence in treatment failure of Streptococcus pyogenes pharyngitis. Eur J Clin Microbiol 16: 233-237.
    • (1997) Eur J Clin Microbiol , vol.16 , pp. 233-237
    • Fitoussi, F.1    Cohen, R.2    Brami, G.3    Doit, C.4    Brahimi, N.5    de la Rocque, F.6    Bingen, E.7
  • 56
    • 0028128306 scopus 로고
    • Signal transduction by the EnvZ-OmpR phosphotransfer system in bacteria
    • Forst SA & Roberts DL (1994) Signal transduction by the EnvZ-OmpR phosphotransfer system in bacteria. Res Microbiol 145: 363-373.
    • (1994) Res Microbiol , vol.145 , pp. 363-373
    • Forst, S.A.1    Roberts, D.L.2
  • 57
    • 0020555349 scopus 로고
    • Gene in the major cotransduction gap of the Escherichia coli K-12 linkage map required for the expression of chromosomal resistance to tetracycline and other antibiotics
    • George AM & Levy SB (1983) Gene in the major cotransduction gap of the Escherichia coli K-12 linkage map required for the expression of chromosomal resistance to tetracycline and other antibiotics. J Bacteriol 155: 541-548.
    • (1983) J Bacteriol , vol.155 , pp. 541-548
    • George, A.M.1    Levy, S.B.2
  • 58
    • 33646353906 scopus 로고    scopus 로고
    • Role of the histone-like nucleoid structuring protein in colonization, motility, and bile-dependent repression of virulence gene expression in Vibrio cholerae
    • Ghosh A, Paul K & Chowdhury R (2006) Role of the histone-like nucleoid structuring protein in colonization, motility, and bile-dependent repression of virulence gene expression in Vibrio cholerae. Infect Immun 74: 3060-3064.
    • (2006) Infect Immun , vol.74 , pp. 3060-3064
    • Ghosh, A.1    Paul, K.2    Chowdhury, R.3
  • 59
    • 78449274705 scopus 로고    scopus 로고
    • Drugs in development for tuberculosis
    • Ginsberg AM (2010) Drugs in development for tuberculosis. Drugs 70: 2201-2214.
    • (2010) Drugs , vol.70 , pp. 2201-2214
    • Ginsberg, A.M.1
  • 60
    • 66249098133 scopus 로고    scopus 로고
    • Genetic architecture of intrinsic antibiotic susceptibility
    • Girgis HS, Hottes AK & Tavazoie S (2009) Genetic architecture of intrinsic antibiotic susceptibility. PLoS One 4: e5629.
    • (2009) PLoS One , vol.4
    • Girgis, H.S.1    Hottes, A.K.2    Tavazoie, S.3
  • 61
    • 33750580687 scopus 로고    scopus 로고
    • Genes involved in intrinsic antibiotic resistance of Acinetobacter baylyi
    • Gomez MJ & Neyfakh AA (2006) Genes involved in intrinsic antibiotic resistance of Acinetobacter baylyi. Antimicrob Agents Ch 50: 3562-3567.
    • (2006) Antimicrob Agents Ch , vol.50 , pp. 3562-3567
    • Gomez, M.J.1    Neyfakh, A.A.2
  • 62
    • 0030065921 scopus 로고    scopus 로고
    • Hns mutant unveils the presence of a latent haemolytic activity in Escherichia coli K-12
    • Gomez-Gomez JM, Blazquez J, Baquero F & Martinez JL (1996) Hns mutant unveils the presence of a latent haemolytic activity in Escherichia coli K-12. Mol Microbiol 19: 909-910.
    • (1996) Mol Microbiol , vol.19 , pp. 909-910
    • Gomez-Gomez, J.M.1    Blazquez, J.2    Baquero, F.3    Martinez, J.L.4
  • 63
    • 1842299280 scopus 로고    scopus 로고
    • H-NS and RpoS regulate emergence of Lac Ara+ mutants of Escherichia coli MCS2
    • Gomez-Gomez JM, Blazquez J, Baquero F & Martinez JL (1997) H-NS and RpoS regulate emergence of Lac Ara+ mutants of Escherichia coli MCS2. J Bacteriol 179: 4620-4622.
    • (1997) J Bacteriol , vol.179 , pp. 4620-4622
    • Gomez-Gomez, J.M.1    Blazquez, J.2    Baquero, F.3    Martinez, J.L.4
  • 64
    • 60149108120 scopus 로고    scopus 로고
    • Regulation of virulence and antibiotic resistance by two-component regulatory systems in Pseudomonas aeruginosa
    • Gooderham WJ & Hancock RE (2009) Regulation of virulence and antibiotic resistance by two-component regulatory systems in Pseudomonas aeruginosa. FEMS Microbiol Rev 33: 279-294.
    • (2009) FEMS Microbiol Rev , vol.33 , pp. 279-294
    • Gooderham, W.J.1    Hancock, R.E.2
  • 65
    • 64049100831 scopus 로고    scopus 로고
    • The sensor kinase PhoQ mediates virulence in Pseudomonas aeruginosa
    • Gooderham WJ, Gellatly SL, Sanschagrin F et al. (2009) The sensor kinase PhoQ mediates virulence in Pseudomonas aeruginosa. Microbiology 155: 699-711.
    • (2009) Microbiology , vol.155 , pp. 699-711
    • Gooderham, W.J.1    Gellatly, S.L.2    Sanschagrin, F.3
  • 66
    • 0029814366 scopus 로고    scopus 로고
    • Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia
    • Govan JR & Deretic V (1996) Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia. Microbiol Rev 60: 539-574.
    • (1996) Microbiol Rev - , vol.60 , pp. 539-574
    • Govan, J.R.1    Deretic, V.2
  • 67
    • 0026454655 scopus 로고
    • Microbiology of lung infection in cystic fibrosis
    • Govan JR & Nelson JW (1992) Microbiology of lung infection in cystic fibrosis. Brit Med Bull 48: 912-930.
    • (1992) Brit Med Bull , vol.48 , pp. 912-930
    • Govan, J.R.1    Nelson, J.W.2
  • 68
    • 0031888905 scopus 로고    scopus 로고
    • The ins and outs of virulence gene expression: Mg2+ as a regulatory signal
    • Groisman EA (1998) The ins and outs of virulence gene expression: Mg2+ as a regulatory signal. Bioessays 20: 96-101.
    • (1998) Bioessays - , vol.20 , pp. 96-101
    • Groisman, E.A.1
  • 69
    • 0035105303 scopus 로고    scopus 로고
    • The pleiotropic two-component regulatory system PhoP-PhoQ
    • Groisman EA (2001) The pleiotropic two-component regulatory system PhoP-PhoQ. J Bacteriol 183: 1835-1842.
    • (2001) J Bacteriol , vol.183 , pp. 1835-1842
    • Groisman, E.A.1
  • 70
    • 0030748655 scopus 로고    scopus 로고
    • Construction and properties of aconitase mutants of Escherichia coli
    • Gruer MJ, Bradbury AJ & Guest JR (1997) Construction and properties of aconitase mutants of Escherichia coli. Microbiology 143: 1837-1846.
    • (1997) Microbiology , vol.143 , pp. 1837-1846
    • Gruer, M.J.1    Bradbury, A.J.2    Guest, J.R.3
  • 71
    • 33746489505 scopus 로고    scopus 로고
    • Cost of cell-cell signalling in Pseudomonas aeruginosa: why it can pay to be signal-blind
    • Haas D (2006) Cost of cell-cell signalling in Pseudomonas aeruginosa: why it can pay to be signal-blind. Nat Rev Microbiol 4: 562; author reply 562.
    • (2006) Nat Rev Microbiol. author reply 562. , vol.4 , pp. 562
    • Haas, D.1
  • 72
    • 0028962716 scopus 로고
    • Mobile gene cassettes and integrons: capture and spread of genes by site-specific recombination
    • Hall RM & Collis CM (1995) Mobile gene cassettes and integrons: capture and spread of genes by site-specific recombination. Mol Microbiol 15: 593-600.
    • (1995) Mol Microbiol - , vol.15 , pp. 593-600
    • Hall, R.M.1    Collis, C.M.2
  • 73
    • 48749089081 scopus 로고    scopus 로고
    • Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli
    • Hansen S, Lewis K & Vulic M (2008) Role of global regulators and nucleotide metabolism in antibiotic tolerance in Escherichia coli. Antimicrob Agents Ch 52: 2718-2726.
    • (2008) Antimicrob Agents Ch , vol.52 , pp. 2718-2726
    • Hansen, S.1    Lewis, K.2    Vulic, M.3
  • 74
    • 0028309532 scopus 로고
    • Role of hns in the virulence phenotype of pathogenic salmonellae
    • Harrison JA, Pickard D, Higgins CF et al. (1994) Role of hns in the virulence phenotype of pathogenic salmonellae. Mol Microbiol 13: 133-140.
    • (1994) Mol Microbiol , vol.13 , pp. 133-140
    • Harrison, J.A.1    Pickard, D.2    Higgins, C.F.3
  • 75
    • 33644829256 scopus 로고    scopus 로고
    • In silico genome-scale reconstruction and validation of the Staphylococcus aureus metabolic network
    • Heinemann M, Kummel A, Ruinatscha R & Panke S (2005) In silico genome-scale reconstruction and validation of the Staphylococcus aureus metabolic network. Biotechnol Bioeng 92: 850-864.
    • (2005) Biotechnol Bioeng , vol.92 , pp. 850-864
    • Heinemann, M.1    Kummel, A.2    Ruinatscha, R.3    Panke, S.4
  • 76
    • 0015024317 scopus 로고
    • Nalidixic acid-resistant mutants of Escherichia coli deficient in isocitrate dehydrogenase
    • Helling RB & Kukora JS (1971) Nalidixic acid-resistant mutants of Escherichia coli deficient in isocitrate dehydrogenase. J Bacteriol 105: 1224-1226.
    • (1971) J Bacteriol , vol.105 , pp. 1224-1226
    • Helling, R.B.1    Kukora, J.S.2
  • 77
    • 0030884768 scopus 로고    scopus 로고
    • AmpC and AmpH, proteins related to the class C beta-lactamases, bind penicillin and contribute to the normal morphology of Escherichia coli
    • Henderson TA, Young KD, Denome SA & Elf PK (1997) AmpC and AmpH, proteins related to the class C beta-lactamases, bind penicillin and contribute to the normal morphology of Escherichia coli. J Bacteriol 179: 6112-6121.
    • (1997) J Bacteriol , vol.179 , pp. 6112-6121
    • Henderson, T.A.1    Young, K.D.2    Denome, S.A.3    Elf, P.K.4
  • 78
    • 0033967977 scopus 로고    scopus 로고
    • Crc is involved in catabolite repression control of the bkd operons of Pseudomonas putida and Pseudomonas aeruginosa
    • Hester KL, Lehman J, Najar F et al. (2000) Crc is involved in catabolite repression control of the bkd operons of Pseudomonas putida and Pseudomonas aeruginosa. J Bacteriol 182: 1144-1149.
    • (2000) J Bacteriol , vol.182 , pp. 1144-1149
    • Hester, K.L.1    Lehman, J.2    Najar, F.3
  • 79
    • 21844434177 scopus 로고    scopus 로고
    • Quorum-sensing-negative (lasR) mutants of Pseudomonas aeruginosa avoid cell lysis and death
    • Heurlier K, Denervaud V, Haenni M, Guy L, Krishnapillai V & Haas D (2005) Quorum-sensing-negative (lasR) mutants of Pseudomonas aeruginosa avoid cell lysis and death. J Bacteriol 187: 4875-4883.
    • (2005) J Bacteriol , vol.187 , pp. 4875-4883
    • Heurlier, K.1    Denervaud, V.2    Haenni, M.3    Guy, L.4    Krishnapillai, V.5    Haas, D.6
  • 80
    • 33644865643 scopus 로고    scopus 로고
    • Impact of quorum sensing on fitness of Pseudomonas aeruginosa
    • Heurlier K, Denervaud V & Haas D (2006) Impact of quorum sensing on fitness of Pseudomonas aeruginosa. Int J Med Microbiol 296: 93-102.
    • (2006) Int J Med Microbiol , vol.296 , pp. 93-102
    • Heurlier, K.1    Denervaud, V.2    Haas, D.3
  • 81
    • 0141928573 scopus 로고    scopus 로고
    • Beta-lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli
    • Hirakawa H, Nishino K, Yamada J, Hirata T & Yamaguchi A (2003) Beta-lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli. J Antimicrob Chemoth 52: 576-582.
    • (2003) J Antimicrob Chemoth , vol.52 , pp. 576-582
    • Hirakawa, H.1    Nishino, K.2    Yamada, J.3    Hirata, T.4    Yamaguchi, A.5
  • 83
    • 77649212763 scopus 로고    scopus 로고
    • Nutrient availability as a mechanism for selection of antibiotic tolerant Pseudomonas aeruginosa within the CF airway
    • Hoffman LR, Richardson AR, Houston LS et al. (2010) Nutrient availability as a mechanism for selection of antibiotic tolerant Pseudomonas aeruginosa within the CF airway. PLoS Pathog 6: e1000712.
    • (2010) PLoS Pathog , vol.6
    • Hoffman, L.R.1    Richardson, A.R.2    Houston, L.S.3
  • 84
    • 0036792119 scopus 로고    scopus 로고
    • Why are bacteria refractory to antimicrobials?
    • Hogan D & Kolter R (2002) Why are bacteria refractory to antimicrobials? Curr Opin Microbiol 5: 472-477.
    • (2002) Curr Opin Microbiol , vol.5 , pp. 472-477
    • Hogan, D.1    Kolter, R.2
  • 86
    • 0035047678 scopus 로고    scopus 로고
    • Large-scale monitoring of pleiotropic regulation of gene expression by the prokaryotic nucleoid-associated protein, H-NS
    • Hommais F, Krin E, Laurent-Winter C et al. (2001) Large-scale monitoring of pleiotropic regulation of gene expression by the prokaryotic nucleoid-associated protein, H-NS. Mol Microbiol 40: 20-36.
    • (2001) Mol Microbiol , vol.40 , pp. 20-36
    • Hommais, F.1    Krin, E.2    Laurent-Winter, C.3
  • 87
    • 0029035034 scopus 로고
    • Nonuniform spatial patterns of respiratory activity within biofilms during disinfection
    • Huang CT, Yu FP, McFeters GA & Stewart PS (1995) Nonuniform spatial patterns of respiratory activity within biofilms during disinfection. Appl Environ Microb 61: 2252-2256.
    • (1995) Appl Environ Microb , vol.61 , pp. 2252-2256
    • Huang, C.T.1    Yu, F.P.2    McFeters, G.A.3    Stewart, P.S.4
  • 88
    • 0028838971 scopus 로고
    • Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling
    • Hunter T (1995) Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 80: 225-236.
    • (1995) Cell - , vol.80 , pp. 225-236
    • Hunter, T.1
  • 89
    • 15544372331 scopus 로고    scopus 로고
    • Rat/MgrA, a regulator of autolysis, is a regulator of virulence genes in Staphylococcus aureus
    • Ingavale S, van Wamel W, Luong TT, Lee CY & Cheung AL (2005) Rat/MgrA, a regulator of autolysis, is a regulator of virulence genes in Staphylococcus aureus. Infect Immun 73: 1423-1431.
    • (2005) Infect Immun , vol.73 , pp. 1423-1431
    • Ingavale, S.1    van Wamel, W.2    Luong, T.T.3    Lee, C.Y.4    Cheung, A.L.5
  • 90
    • 33645060962 scopus 로고
    • Mitteilungen über einen variablen Typhusstamm (Bacterium typhi mutabile), sowie über eine eigentümliche hemmende Wirkung des gewöhnlichen agar, verursacht durch autoklavierung
    • Jacobsen KA (1910) Mitteilungen über einen variablen Typhusstamm (Bacterium typhi mutabile), sowie über eine eigentümliche hemmende Wirkung des gewöhnlichen agar, verursacht durch autoklavierung. Zentralbl Bakteriol [Orig A] 56: 208-216.
    • (1910) Zentralbl Bakteriol [Orig A] , vol.56 , pp. 208-216
    • Jacobsen, K.A.1
  • 91
    • 33646824923 scopus 로고    scopus 로고
    • ppGpp: stringent response and survival
    • Jain V, Kumar M & Chatterji D (2006) ppGpp: stringent response and survival. J Microbiol 44: 1-10.
    • (2006) J Microbiol - , vol.44 , pp. 1-10
    • Jain, V.1    Kumar, M.2    Chatterji, D.3
  • 92
    • 30744447972 scopus 로고    scopus 로고
    • Identification of Listeria monocytogenes genes contributing to intracellular replication by expression profiling and mutant screening
    • Joseph B, Przybilla K, Stuhler C, Schauer K, Slaghuis J, Fuchs TM & Goebel W (2006) Identification of Listeria monocytogenes genes contributing to intracellular replication by expression profiling and mutant screening. J Bacteriol 188: 556-568.
    • (2006) J Bacteriol , vol.188 , pp. 556-568
    • Joseph, B.1    Przybilla, K.2    Stuhler, C.3    Schauer, K.4    Slaghuis, J.5    Fuchs, T.M.6    Goebel, W.7
  • 93
    • 70349763429 scopus 로고    scopus 로고
    • Interplay of efflux, impermeability, and AmpC activity contributes to cefuroxime resistance in clinical, non-ESBL-producing isolates of Escherichia coli
    • Kallman O, Giske CG, Samuelsen O, Wretlind B, Kalin M & Olsson-Liljequist B (2009) Interplay of efflux, impermeability, and AmpC activity contributes to cefuroxime resistance in clinical, non-ESBL-producing isolates of Escherichia coli. Microb Drug Resist 15: 91-95.
    • (2009) Microb Drug Resist , vol.15 , pp. 91-95
    • Kallman, O.1    Giske, C.G.2    Samuelsen, O.3    Wretlind, B.4    Kalin, M.5    Olsson-Liljequist, B.6
  • 94
    • 23044488472 scopus 로고    scopus 로고
    • The Mycobacterium tuberculosis serine/threonine kinases PknA and PknB: substrate identification and regulation of cell shape
    • Kang CM, Abbott DW, Park ST, Dascher CC, Cantley LC & Husson RN (2005) The Mycobacterium tuberculosis serine/threonine kinases PknA and PknB: substrate identification and regulation of cell shape. Gene Dev 19: 1692-1704.
    • (2005) Gene Dev - , vol.19 , pp. 1692-1704
    • Kang, C.M.1    Abbott, D.W.2    Park, S.T.3    Dascher, C.C.4    Cantley, L.C.5    Husson, R.N.6
  • 95
    • 10044266575 scopus 로고    scopus 로고
    • Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli
    • Keren I, Shah D, Spoering A, Kaldalu N & Lewis K (2004) Specialized persister cells and the mechanism of multidrug tolerance in Escherichia coli. J Bacteriol 186: 8172-8180.
    • (2004) J Bacteriol , vol.186 , pp. 8172-8180
    • Keren, I.1    Shah, D.2    Spoering, A.3    Kaldalu, N.4    Lewis, K.5
  • 96
    • 0347930793 scopus 로고    scopus 로고
    • Swarming populations of Salmonella represent a unique physiological state coupled to multiple mechanisms of antibiotic resistance
    • Kim W & Surette MG (2003) Swarming populations of Salmonella represent a unique physiological state coupled to multiple mechanisms of antibiotic resistance. Biol Proced Online 5: 189-196.
    • (2003) Biol Proced Online , vol.5 , pp. 189-196
    • Kim, W.1    Surette, M.G.2
  • 97
    • 0038643291 scopus 로고    scopus 로고
    • Swarm-cell differentiation in Salmonella enterica serovar typhimurium results in elevated resistance to multiple antibiotics
    • Kim W, Killam T, Sood V & Surette MG (2003) Swarm-cell differentiation in Salmonella enterica serovar typhimurium results in elevated resistance to multiple antibiotics. J Bacteriol 185: 3111-3117.
    • (2003) J Bacteriol , vol.185 , pp. 3111-3117
    • Kim, W.1    Killam, T.2    Sood, V.3    Surette, M.G.4
  • 98
    • 34548213103 scopus 로고    scopus 로고
    • A common mechanism of cellular death induced by bactericidal antibiotics
    • Kohanski MA, Dwyer DJ, Hayete B, Lawrence CA & Collins JJ (2007) A common mechanism of cellular death induced by bactericidal antibiotics. Cell 130: 797-810.
    • (2007) Cell , vol.130 , pp. 797-810
    • Kohanski, M.A.1    Dwyer, D.J.2    Hayete, B.3    Lawrence, C.A.4    Collins, J.J.5
  • 99
    • 55449126342 scopus 로고    scopus 로고
    • Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death
    • Kohanski MA, Dwyer DJ, Wierzbowski J, Cottarel G & Collins JJ (2008) Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death. Cell 135: 679-690.
    • (2008) Cell , vol.135 , pp. 679-690
    • Kohanski, M.A.1    Dwyer, D.J.2    Wierzbowski, J.3    Cottarel, G.4    Collins, J.J.5
  • 100
  • 101
    • 0034871821 scopus 로고    scopus 로고
    • Overexpression of the MexEF-OprN multidrug efflux system affects cell-to-cell signaling in Pseudomonas aeruginosa
    • Kohler T, van Delden C, Curty LK, Hamzehpour MM & Pechere JC (2001) Overexpression of the MexEF-OprN multidrug efflux system affects cell-to-cell signaling in Pseudomonas aeruginosa. J Bacteriol 183: 5213-5222.
    • (2001) J Bacteriol , vol.183 , pp. 5213-5222
    • Kohler, T.1    van Delden, C.2    Curty, L.K.3    Hamzehpour, M.M.4    Pechere, J.C.5
  • 103
    • 18844368812 scopus 로고    scopus 로고
    • Bacterial persistence: a model of survival in changing environments
    • Kussell E, Kishony R, Balaban NQ & Leibler S (2005) Bacterial persistence: a model of survival in changing environments. Genetics 169: 1807-1814.
    • (2005) Genetics - , vol.169 , pp. 1807-1814
    • Kussell, E.1    Kishony, R.2    Balaban, N.Q.3    Leibler, S.4
  • 104
    • 0030983671 scopus 로고    scopus 로고
    • Role of Escherichia coli histone-like nucleoid-structuring protein in bacterial metabolism and stress response - identification of targets by two-dimensional electrophoresis
    • Laurent-Winter C, Ngo S, Danchin A & Bertin P (1997) Role of Escherichia coli histone-like nucleoid-structuring protein in bacterial metabolism and stress response - identification of targets by two-dimensional electrophoresis. Eur J Biochem 244: 767-773.
    • (1997) Eur J Biochem , vol.244 , pp. 767-773
    • Laurent-Winter, C.1    Ngo, S.2    Danchin, A.3    Bertin, P.4
  • 105
    • 0032782869 scopus 로고    scopus 로고
    • The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids
    • Lee EH & Shafer WM (1999) The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids. Mol Microbiol 33: 839-845.
    • (1999) Mol Microbiol , vol.33 , pp. 839-845
    • Lee, E.H.1    Shafer, W.M.2
  • 106
    • 0344666702 scopus 로고    scopus 로고
    • FarR regulates the farAB-encoded efflux pump of Neisseria gonorrhoeae via an MtrR regulatory mechanism
    • Lee EH, Rouquette-Loughlin C, Folster JP & Shafer WM (2003) FarR regulates the farAB-encoded efflux pump of Neisseria gonorrhoeae via an MtrR regulatory mechanism. J Bacteriol 185: 7145-7152.
    • (2003) J Bacteriol , vol.185 , pp. 7145-7152
    • Lee, E.H.1    Rouquette-Loughlin, C.2    Folster, J.P.3    Shafer, W.M.4
  • 107
    • 33745192359 scopus 로고
    • Mode of action of penicillin: I. Bacterial growth and penicillin activity-Staphylococcus aureus FDA
    • Lee SW, Foley EJ & Epstein JA (1944) Mode of action of penicillin: I. Bacterial growth and penicillin activity-Staphylococcus aureus FDA. J Bacteriol 48: 393-399.
    • (1944) J Bacteriol - , vol.48 , pp. 393-399
    • Lee, S.W.1    Foley, E.J.2    Epstein, J.A.3
  • 108
    • 0025015538 scopus 로고
    • Identification of a gene that positively regulates expression of listeriolysin, the major virulence factor of Listeria monocytogenes
    • Leimeister-Wachter M, Haffner C, Domann E, Goebel W & Chakraborty T (1990) Identification of a gene that positively regulates expression of listeriolysin, the major virulence factor of Listeria monocytogenes. P Natl Acad Sci USA 87: 8336-8340.
    • (1990) P Natl Acad Sci USA , vol.87 , pp. 8336-8340
    • Leimeister-Wachter, M.1    Haffner, C.2    Domann, E.3    Goebel, W.4    Chakraborty, T.5
  • 109
    • 33745189789 scopus 로고    scopus 로고
    • Non-inherited antibiotic resistance
    • Levin BR & Rozen DE (2006) Non-inherited antibiotic resistance. Nat Rev Microbiol 4: 556-562.
    • (2006) Nat Rev Microbiol , vol.4 , pp. 556-562
    • Levin, B.R.1    Rozen, D.E.2
  • 110
    • 77955628762 scopus 로고    scopus 로고
    • Persister cells
    • Lewis K (2010) Persister cells. Annu Rev Microbiol 64: 357-372.
    • (2010) Annu Rev Microbiol , vol.64 , pp. 357-372
    • Lewis, K.1
  • 111
    • 34547614085 scopus 로고    scopus 로고
    • Regulation of carbon and nitrogen utilization by CbrAB and NtrBC two-component systems in Pseudomonas aeruginosa
    • Li W & Lu CD (2007) Regulation of carbon and nitrogen utilization by CbrAB and NtrBC two-component systems in Pseudomonas aeruginosa. J Bacteriol 189: 5413-5420.
    • (2007) J Bacteriol , vol.189 , pp. 5413-5420
    • Li, W.1    Lu, C.D.2
  • 112
    • 0037395820 scopus 로고    scopus 로고
    • Role of the acetyltransferase AAC(6')-Iz modifying enzyme in aminoglycoside resistance in Stenotrophomonas maltophilia
    • Li XZ, Zhang L, McKay GA & Poole K (2003) Role of the acetyltransferase AAC(6')-Iz modifying enzyme in aminoglycoside resistance in Stenotrophomonas maltophilia. J Antimicrob Chemoth 51: 803-811.
    • (2003) J Antimicrob Chemoth , vol.51 , pp. 803-811
    • Li, X.Z.1    Zhang, L.2    McKay, G.A.3    Poole, K.4
  • 113
    • 14544300496 scopus 로고    scopus 로고
    • Overexpression of the multidrug efflux pumps MexCD-OprJ and MexEF-OprN is associated with a reduction of type III secretion in Pseudomonas aeruginosa
    • Linares JF, Lopez JA, Camafeita E, Albar JP, Rojo F & Martinez JL (2005) Overexpression of the multidrug efflux pumps MexCD-OprJ and MexEF-OprN is associated with a reduction of type III secretion in Pseudomonas aeruginosa. J Bacteriol 187: 1384-1391.
    • (2005) J Bacteriol , vol.187 , pp. 1384-1391
    • Linares, J.F.1    Lopez, J.A.2    Camafeita, E.3    Albar, J.P.4    Rojo, F.5    Martinez, J.L.6
  • 116
    • 0000297348 scopus 로고
    • Contribution of chromosomal beta-lactamases to beta-lactam resistance in enterobacteria
    • Lindberg F & Normark S (1986) Contribution of chromosomal beta-lactamases to beta-lactam resistance in enterobacteria. Rev Infect Dis 8 (suppl 3): S292-S304.
    • (1986) Rev Infect Dis , vol.8 , Issue.SUPPL. 3
    • Lindberg, F.1    Normark, S.2
  • 118
    • 14144252921 scopus 로고    scopus 로고
    • Enhanced in vivo fitness of fluoroquinolone-resistant Campylobacter jejuni in the absence of antibiotic selection pressure
    • Luo N, Pereira S, Sahin O, Lin J, Huang S, Michel L & Zhang Q (2005) Enhanced in vivo fitness of fluoroquinolone-resistant Campylobacter jejuni in the absence of antibiotic selection pressure. P Natl Acad Sci USA 102: 541-546.
    • (2005) P Natl Acad Sci USA , vol.102 , pp. 541-546
    • Luo, N.1    Pereira, S.2    Sahin, O.3    Lin, J.4    Huang, S.5    Michel, L.6    Zhang, Q.7
  • 119
    • 33644755944 scopus 로고    scopus 로고
    • Transcription profiling of the mgrA regulon in Staphylococcus aureus
    • Luong TT, Dunman PM, Murphy E, Projan SJ & Lee CY (2006) Transcription profiling of the mgrA regulon in Staphylococcus aureus. J Bacteriol 188: 1899-1910.
    • (2006) J Bacteriol , vol.188 , pp. 1899-1910
    • Luong, T.T.1    Dunman, P.M.2    Murphy, E.3    Projan, S.J.4    Lee, C.Y.5
  • 120
  • 121
    • 39749166860 scopus 로고    scopus 로고
    • Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation
    • Macek B, Gnad F, Soufi B, Kumar C, Olsen JV, Mijakovic I & Mann M (2008) Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation. Mol Cell Proteomics 7: 299-307.
    • (2008) Mol Cell Proteomics , vol.7 , pp. 299-307
    • Macek, B.1    Gnad, F.2    Soufi, B.3    Kumar, C.4    Olsen, J.V.5    Mijakovic, I.6    Mann, M.7
  • 122
    • 0033759942 scopus 로고    scopus 로고
    • Role of Pseudomonas aeruginosa PhoP-PhoQ in resistance to antimicrobial cationic peptides and aminoglycosides
    • Macfarlane EL, Kwasnicka A & Hancock RE (2000) Role of Pseudomonas aeruginosa PhoP-PhoQ in resistance to antimicrobial cationic peptides and aminoglycosides. Microbiology 146: 2543-2554.
    • (2000) Microbiology , vol.146 , pp. 2543-2554
    • Macfarlane, E.L.1    Kwasnicka, A.2    Hancock, R.E.3
  • 123
    • 0025790176 scopus 로고
    • Cloning of a catabolite repression control (crc) gene from Pseudomonas aeruginosa, expression of the gene in Escherichia coli, and identification of the gene product in Pseudomonas aeruginosa
    • MacGregor CH, Wolff JA, Arora SK & Phibbs PV Jr (1991) Cloning of a catabolite repression control (crc) gene from Pseudomonas aeruginosa, expression of the gene in Escherichia coli, and identification of the gene product in Pseudomonas aeruginosa. J Bacteriol 173: 7204-7212.
    • (1991) J Bacteriol , vol.173 , pp. 7204-7212
    • MacGregor, C.H.1    Wolff, J.A.2    Arora, S.K.3    Phibbs Jr, P.V.4
  • 124
    • 0029796309 scopus 로고    scopus 로고
    • The nucleotide sequence of the Pseudomonas aeruginosa pyrE-crc-rph region and the purification of the crc gene product
    • MacGregor CH, Arora SK, Hager PW, Dail MB & Phibbs PV Jr (1996) The nucleotide sequence of the Pseudomonas aeruginosa pyrE-crc-rph region and the purification of the crc gene product. J Bacteriol 178: 5627-5635.
    • (1996) J Bacteriol , vol.178 , pp. 5627-5635
    • MacGregor, C.H.1    Arora, S.K.2    Hager, P.W.3    Dail, M.B.4    Phibbs Jr, P.V.5
  • 125
    • 0033074395 scopus 로고    scopus 로고
    • The chromosomal 2'-N-acetyltransferase of Providencia stuartii: physiological functions and genetic regulation
    • Macinga DR & Rather PN (1999) The chromosomal 2'-N-acetyltransferase of Providencia stuartii: physiological functions and genetic regulation. Front Biosci 4: D132-D140.
    • (1999) Front Biosci - , vol.4
    • Macinga, D.R.1    Rather, P.N.2
  • 127
    • 47749155981 scopus 로고    scopus 로고
    • Antibiotics and antibiotic resistance genes in natural environments
    • Martinez JL (2008) Antibiotics and antibiotic resistance genes in natural environments. Science 321: 365-367.
    • (2008) Science , vol.321 , pp. 365-367
    • Martinez, J.L.1
  • 128
    • 0033936567 scopus 로고    scopus 로고
    • Mutation frequencies and antibiotic resistance
    • Martinez JL & Baquero F (2000) Mutation frequencies and antibiotic resistance. Antimicrob Agents Ch 44: 1771-1777.
    • (2000) Antimicrob Agents Ch , vol.44 , pp. 1771-1777
    • Martinez, J.L.1    Baquero, F.2
  • 129
    • 0036782279 scopus 로고    scopus 로고
    • Interactions among strategies associated with bacterial infection; pathogenicity, epidemicity, and antibiotic resistance
    • Martinez JL & Baquero F (2002) Interactions among strategies associated with bacterial infection: pathogenicity, epidemicity, and antibiotic resistance. Clin Microbiol Rev 15: 647-679.
    • (2002) Clin Microbiol Rev - , vol.15 , pp. 647-679
    • Martinez, J.L.1    Baquero, F.2
  • 134
    • 0031973490 scopus 로고    scopus 로고
    • Kinship and diversification of bacterial penicillin-binding proteins and beta-lactamases
    • Massova I & Mobashery S (1998) Kinship and diversification of bacterial penicillin-binding proteins and beta-lactamases. Antimicrob Agents Ch 42: 1-17.
    • (1998) Antimicrob Agents Ch , vol.42 , pp. 1-17
    • Massova, I.1    Mobashery, S.2
  • 135
    • 0000164959 scopus 로고
    • Fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. I. The persistence of drug-susceptible tubercle bacilli in the tissues despite prolonged antimicrobial therapy
    • McCune RM Jr & Tompsett R (1956) Fate of Mycobacterium tuberculosis in mouse tissues as determined by the microbial enumeration technique. I. The persistence of drug-susceptible tubercle bacilli in the tissues despite prolonged antimicrobial therapy. J Exp Med 104: 737-762.
    • (1956) J Exp Med , vol.104 , pp. 737-762
    • McCune Jr, R.M.1    Tompsett, R.2
  • 136
    • 0001580409 scopus 로고
    • Microbial persistence
    • Mc Dermott W (1958) Microbial persistence. Yale J Biol Med 30: 257-291.
    • (1958) Yale J Biol Med , vol.30 , pp. 257-291
    • Mc Dermott, W.1
  • 137
    • 57349088170 scopus 로고    scopus 로고
    • Genetic adaptation of Pseudomonas aeruginosa to the airways of cystic fibrosis patients is catalyzed by hypermutation
    • Mena A, Smith EE, Burns JL, Speert DP, Moskowitz SM, Perez JL & Oliver A (2008) Genetic adaptation of Pseudomonas aeruginosa to the airways of cystic fibrosis patients is catalyzed by hypermutation. J Bacteriol 190: 7910-7917.
    • (2008) J Bacteriol , vol.190 , pp. 7910-7917
    • Mena, A.1    Smith, E.E.2    Burns, J.L.3    Speert, D.P.4    Moskowitz, S.M.5    Perez, J.L.6    Oliver, A.7
  • 138
    • 0043127209 scopus 로고    scopus 로고
    • Structural aspects for evolution of beta-lactamases from penicillin-binding proteins
    • Meroueh SO, Minasov G, Lee W, Shoichet BK & Mobashery S (2003) Structural aspects for evolution of beta-lactamases from penicillin-binding proteins. J Am Chem Soc 125: 9612-9618.
    • (2003) J Am Chem Soc , vol.125 , pp. 9612-9618
    • Meroueh, S.O.1    Minasov, G.2    Lee, W.3    Shoichet, B.K.4    Mobashery, S.5
  • 139
    • 0025140705 scopus 로고
    • Signal transduction and gene regulation through the phosphorylation of two regulatory components: the molecular basis for the osmotic regulation of the porin genes
    • Mizuno T & Mizushima S (1990) Signal transduction and gene regulation through the phosphorylation of two regulatory components: the molecular basis for the osmotic regulation of the porin genes. Mol Microbiol 4: 1077-1082.
    • (1990) Mol Microbiol - , vol.4 , pp. 1077-1082
    • Mizuno, T.1    Mizushima, S.2
  • 140
    • 70350668611 scopus 로고    scopus 로고
    • 2+ concentrations, and is highly interconnected with a wide variety of cellular processes
    • 2+ concentrations, and is highly interconnected with a wide variety of cellular processes. Biochem J 424: 129-141.
    • (2009) Biochem J , vol.424 , pp. 129-141
    • Montero, M.1    Eydallin, G.2    Viale, A.M.3
  • 141
    • 1342346618 scopus 로고    scopus 로고
    • The Pseudomonas putida Crc global regulator controls the expression of genes from several chromosomal catabolic pathways for aromatic compounds
    • Morales G, Linares JF, Beloso A, Albar JP, Martinez JL & Rojo F (2004a) The Pseudomonas putida Crc global regulator controls the expression of genes from several chromosomal catabolic pathways for aromatic compounds. J Bacteriol 186: 1337-1344.
    • (2004) J Bacteriol , vol.186 , pp. 1337-1344
    • Morales, G.1    Linares, J.F.2    Beloso, A.3    Albar, J.P.4    Martinez, J.L.5    Rojo, F.6
  • 142
    • 3042610184 scopus 로고    scopus 로고
    • Structure of Pseudomonas aeruginosa populations analyzed by single nucleotide polymorphism and pulsed-field gel electrophoresis genotyping
    • Morales G, Wiehlmann L, Gudowius P, van Delden C, Tummler B, Martinez JL & Rojo F (2004b) Structure of Pseudomonas aeruginosa populations analyzed by single nucleotide polymorphism and pulsed-field gel electrophoresis genotyping. J Bacteriol 186: 4228-4237.
    • (2004) J Bacteriol , vol.186 , pp. 4228-4237
    • Morales, G.1    Wiehlmann, L.2    Gudowius, P.3    van Delden, C.4    Tummler, B.5    Martinez, J.L.6    Rojo, F.7
  • 143
    • 39749101662 scopus 로고    scopus 로고
    • The target for the Pseudomonas putida Crc global regulator in the benzoate degradation pathway is the BenR transcriptional regulator
    • Moreno R & Rojo F (2008) The target for the Pseudomonas putida Crc global regulator in the benzoate degradation pathway is the BenR transcriptional regulator. J Bacteriol 190: 1539-1545.
    • (2008) J Bacteriol , vol.190 , pp. 1539-1545
    • Moreno, R.1    Rojo, F.2
  • 144
    • 34247509259 scopus 로고    scopus 로고
    • The Pseudomonas putida Crc global regulator is an RNA binding protein that inhibits translation of the AlkS transcriptional regulator
    • Moreno R, Ruiz-Manzano A, Yuste L & Rojo F (2007) The Pseudomonas putida Crc global regulator is an RNA binding protein that inhibits translation of the AlkS transcriptional regulator. Mol Microbiol 64: 665-675.
    • (2007) Mol Microbiol , vol.64 , pp. 665-675
    • Moreno, R.1    Ruiz-Manzano, A.2    Yuste, L.3    Rojo, F.4
  • 145
    • 67649201763 scopus 로고    scopus 로고
    • The Pseudomonas putida Crc global regulator controls the hierarchical assimilation of amino acids in a complete medium; evidence from proteomic and genomic analyses
    • Moreno R, Martinez-Gomariz M, Yuste L, Gil C & Rojo F (2009a) The Pseudomonas putida Crc global regulator controls the hierarchical assimilation of amino acids in a complete medium: evidence from proteomic and genomic analyses. Proteomics 9: 2910-2928.
    • (2009) Proteomics - , vol.9 , pp. 2910-2928
    • Moreno, R.1    Martinez-Gomariz, M.2    Yuste, L.3    Gil, C.4    Rojo, F.5
  • 146
    • 75649099354 scopus 로고    scopus 로고
    • The Crc global regulator binds to an unpaired A-rich motif at the Pseudomonas putida alkS mRNA coding sequence and inhibits translation initiation
    • Moreno R, Marzi S, Romby P & Rojo F (2009b) The Crc global regulator binds to an unpaired A-rich motif at the Pseudomonas putida alkS mRNA coding sequence and inhibits translation initiation. Nucleic Acids Res 37: 7678-7690.
    • (2009) Nucleic Acids Res , vol.37 , pp. 7678-7690
    • Moreno, R.1    Marzi, S.2    Romby, P.3    Rojo, F.4
  • 148
    • 0027202616 scopus 로고
    • The accumulation of five antibacterial agents in porin-deficient mutants of Escherichia coli
    • Mortimer PG & Piddock LJ (1993) The accumulation of five antibacterial agents in porin-deficient mutants of Escherichia coli. J Antimicrob Chemoth 32: 195-213.
    • (1993) J Antimicrob Chemoth , vol.32 , pp. 195-213
    • Mortimer, P.G.1    Piddock, L.J.2
  • 149
    • 57149111485 scopus 로고    scopus 로고
    • Extracellular DNA chelates cations and induces antibiotic resistance in Pseudomonas aeruginosa biofilms
    • Mulcahy H, Charron-Mazenod L & Lewenza S (2008) Extracellular DNA chelates cations and induces antibiotic resistance in Pseudomonas aeruginosa biofilms. PLoS Pathog 4: e1000213.
    • (2008) PLoS Pathog , vol.4
    • Mulcahy, H.1    Charron-Mazenod, L.2    Lewenza, S.3
  • 150
    • 79952348328 scopus 로고    scopus 로고
    • A two-component regulatory system interconnects resistance to polymyxins, aminoglycosides, fluoroquinolones, and beta-lactams in Pseudomonas aeruginosa
    • Muller C, Plesiat P & Jeannot K (2011) A two-component regulatory system interconnects resistance to polymyxins, aminoglycosides, fluoroquinolones, and beta-lactams in Pseudomonas aeruginosa. Antimicrob Agents Ch 55: 1211-1221.
    • (2011) Antimicrob Agents Ch , vol.55 , pp. 1211-1221
    • Muller, C.1    Plesiat, P.2    Jeannot, K.3
  • 151
    • 33746629034 scopus 로고    scopus 로고
    • Role of histone-like proteins H-NS and StpA in expression of virulence determinants of uropathogenic Escherichia coli
    • Muller CM, Dobrindt U, Nagy G, Emody L, Uhlin BE & Hacker J (2006) Role of histone-like proteins H-NS and StpA in expression of virulence determinants of uropathogenic Escherichia coli. J Bacteriol 188: 5428-5438.
    • (2006) J Bacteriol , vol.188 , pp. 5428-5438
    • Muller, C.M.1    Dobrindt, U.2    Nagy, G.3    Emody, L.4    Uhlin, B.E.5    Hacker, J.6
  • 152
    • 0035180389 scopus 로고    scopus 로고
    • Role of the nucleoid-associated protein H-NS in the synthesis of virulence factors in the phytopathogenic bacterium Erwinia chrysanthemi
    • Nasser W, Faelen M, Hugouvieux-Cotte-Pattat N & Reverchon S (2001) Role of the nucleoid-associated protein H-NS in the synthesis of virulence factors in the phytopathogenic bacterium Erwinia chrysanthemi. Mol Plant Microbe In 14: 10-20.
    • (2001) Mol Plant Microbe In , vol.14 , pp. 10-20
    • Nasser, W.1    Faelen, M.2    Hugouvieux-Cotte-Pattat, N.3    Reverchon, S.4
  • 154
    • 0032173598 scopus 로고    scopus 로고
    • Multiple antibiotic resistance and efflux
    • Nikaido H (1998) Multiple antibiotic resistance and efflux. Curr Opin Microbiol 1: 516-523.
    • (1998) Curr Opin Microbiol , vol.1 , pp. 516-523
    • Nikaido, H.1
  • 155
    • 1342346607 scopus 로고    scopus 로고
    • Role of histone-like protein H-NS in multidrug resistance of Escherichia coli
    • Nishino K & Yamaguchi A (2004) Role of histone-like protein H-NS in multidrug resistance of Escherichia coli. J Bacteriol 186: 1423-1429.
    • (2004) J Bacteriol , vol.186 , pp. 1423-1429
    • Nishino, K.1    Yamaguchi, A.2
  • 156
    • 67749088409 scopus 로고    scopus 로고
    • H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF
    • Nishino K, Hayashi-Nishino M & Yamaguchi A (2009) H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF. Antimicrob Agents Ch 53: 3541-3543.
    • (2009) Antimicrob Agents Ch , vol.53 , pp. 3541-3543
    • Nishino, K.1    Hayashi-Nishino, M.2    Yamaguchi, A.3
  • 157
    • 0034962534 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa reveals high intrinsic resistance to penem antibiotics; penem resistance mechanisms and their interplay
    • Okamoto K, Gotoh N & Nishino T (2001) Pseudomonas aeruginosa reveals high intrinsic resistance to penem antibiotics: penem resistance mechanisms and their interplay. Antimicrob Agents Ch 45: 1964-1971.
    • (2001) Antimicrob Agents Ch - , vol.45 , pp. 1964-1971
    • Okamoto, K.1    Gotoh, N.2    Nishino, T.3
  • 158
    • 34948824379 scopus 로고    scopus 로고
    • Role of nucleoid-associated proteins Hha and H-NS in expression of Salmonella enterica activators HilD, HilC, and RtsA required for cell invasion
    • Olekhnovich IN & Kadner RJ (2007) Role of nucleoid-associated proteins Hha and H-NS in expression of Salmonella enterica activators HilD, HilC, and RtsA required for cell invasion. J Bacteriol 189: 6882-6890.
    • (2007) J Bacteriol , vol.189 , pp. 6882-6890
    • Olekhnovich, I.N.1    Kadner, R.J.2
  • 159
    • 33947401483 scopus 로고    scopus 로고
    • Identification of genes involved in swarming motility using a Pseudomonas aeruginosa PAO1 mini-Tn5-lux mutant library
    • Overhage J, Lewenza S, Marr AK & Hancock RE (2007) Identification of genes involved in swarming motility using a Pseudomonas aeruginosa PAO1 mini-Tn5-lux mutant library. J Bacteriol 189: 2164-2169.
    • (2007) J Bacteriol , vol.189 , pp. 2164-2169
    • Overhage, J.1    Lewenza, S.2    Marr, A.K.3    Hancock, R.E.4
  • 160
    • 41949114474 scopus 로고    scopus 로고
    • Swarming of Pseudomonas aeruginosa is a complex adaptation leading to increased production of virulence factors and antibiotic resistance
    • Overhage J, Bains M, Brazas MD & Hancock RE (2008) Swarming of Pseudomonas aeruginosa is a complex adaptation leading to increased production of virulence factors and antibiotic resistance. J Bacteriol 190: 2671-2679.
    • (2008) J Bacteriol , vol.190 , pp. 2671-2679
    • Overhage, J.1    Bains, M.2    Brazas, M.D.3    Hancock, R.E.4
  • 161
  • 162
    • 33748484297 scopus 로고    scopus 로고
    • Co-regulation of motility, exoenzyme and antibiotic production by the EnvZ-OmpR-FlhDC-FliA pathway in Xenorhabdus nematophila
    • Park D & Forst S (2006) Co-regulation of motility, exoenzyme and antibiotic production by the EnvZ-OmpR-FlhDC-FliA pathway in Xenorhabdus nematophila. Mol Microbiol 61: 1397-1412.
    • (2006) Mol Microbiol , vol.61 , pp. 1397-1412
    • Park, D.1    Forst, S.2
  • 163
    • 38649112604 scopus 로고    scopus 로고
    • Uncovering new metabolic capabilities of Bacillus subtilis using phenotype profiling of rifampin-resistant rpoB mutants
    • Perkins AE & Nicholson WL (2008) Uncovering new metabolic capabilities of Bacillus subtilis using phenotype profiling of rifampin-resistant rpoB mutants. J Bacteriol 190: 807-814.
    • (2008) J Bacteriol , vol.190 , pp. 807-814
    • Perkins, A.E.1    Nicholson, W.L.2
  • 164
    • 63749115101 scopus 로고    scopus 로고
    • Bacterial nucleotide-based second messengers
    • Pesavento C & Hengge R (2009) Bacterial nucleotide-based second messengers. Curr Opin Microbiol 12: 170-176.
    • (2009) Curr Opin Microbiol , vol.12 , pp. 170-176
    • Pesavento, C.1    Hengge, R.2
  • 165
    • 79251537963 scopus 로고    scopus 로고
    • A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy
    • Pethe K, Sequeira PC, Agarwalla S et al. (2010) A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy. Nat Commun 1: 1-8.
    • (2010) Nat Commun , vol.1 , pp. 1-8
    • Pethe, K.1    Sequeira, P.C.2    Agarwalla, S.3
  • 166
    • 33747154459 scopus 로고    scopus 로고
    • Multidrug-resistance efflux pumps - not just for resistance
    • Piddock LJ (2006) Multidrug-resistance efflux pumps - not just for resistance. Nat Rev Microbiol 4: 629-636.
    • (2006) Nat Rev Microbiol , vol.4 , pp. 629-636
    • Piddock, L.J.1
  • 167
    • 48749128095 scopus 로고    scopus 로고
    • Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2
    • Pranting M, Negrea A, Rhen M & Andersson DI (2008) Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2. Antimicrob Agents Ch 52: 2734-2741.
    • (2008) Antimicrob Agents Ch , vol.52 , pp. 2734-2741
    • Pranting, M.1    Negrea, A.2    Rhen, M.3    Andersson, D.I.4
  • 168
    • 0028870651 scopus 로고
    • Persistent and relapsing infections associated with small-colony variants of Staphylococcus aureus
    • Proctor RA, van Langevelde P, Kristjansson M, Maslow JN & Arbeit RD (1995) Persistent and relapsing infections associated with small-colony variants of Staphylococcus aureus. Clin Infect Dis 20: 95-102.
    • (1995) Clin Infect Dis , vol.20 , pp. 95-102
    • Proctor, R.A.1    van Langevelde, P.2    Kristjansson, M.3    Maslow, J.N.4    Arbeit, R.D.5
  • 170
    • 34249794867 scopus 로고    scopus 로고
    • Spatial patterns of DNA replication, protein synthesis, and oxygen concentration within bacterial biofilms reveal diverse physiological states
    • Rani SA, Pitts B, Beyenal H et al. (2007) Spatial patterns of DNA replication, protein synthesis, and oxygen concentration within bacterial biofilms reveal diverse physiological states. J Bacteriol 189: 4223-4233.
    • (2007) J Bacteriol , vol.189 , pp. 4223-4233
    • Rani, S.A.1    Pitts, B.2    Beyenal, H.3
  • 171
    • 77954645140 scopus 로고    scopus 로고
    • Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts
    • Rau MH, Hansen SK, Johansen HK et al. (2010) Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts. Environ Microbiol 12: 1643-1658.
    • (2010) Environ Microbiol , vol.12 , pp. 1643-1658
    • Rau, M.H.1    Hansen, S.K.2    Johansen, H.K.3
  • 172
    • 0025869458 scopus 로고
    • Factors determining resistance to beta-lactam combined with beta-lactamase inhibitors in Escherichia coli
    • Reguera JA, Baquero F, Perez-Diaz JC & Martinez JL (1991) Factors determining resistance to beta-lactam combined with beta-lactamase inhibitors in Escherichia coli. J Antimicrob Chemoth 27: 569-575.
    • (1991) J Antimicrob Chemoth , vol.27 , pp. 569-575
    • Reguera, J.A.1    Baquero, F.2    Perez-Diaz, J.C.3    Martinez, J.L.4
  • 173
    • 0030778201 scopus 로고    scopus 로고
    • Glucose-1-phosphate utilization by Listeria monocytogenes is PrfA dependent and coordinately expressed with virulence factors
    • Ripio MT, Brehm K, Lara M, Suarez M & Vazquez-Boland JA (1997) Glucose-1-phosphate utilization by Listeria monocytogenes is PrfA dependent and coordinately expressed with virulence factors. J Bacteriol 179: 7174-7180.
    • (1997) J Bacteriol , vol.179 , pp. 7174-7180
    • Ripio, M.T.1    Brehm, K.2    Lara, M.3    Suarez, M.4    Vazquez-Boland, J.A.5
  • 174
    • 77955132055 scopus 로고    scopus 로고
    • Carbon catabolite repression in Pseudomonas: optimizing metabolic versatility and interactions with the environment
    • Rojo F (2010) Carbon catabolite repression in Pseudomonas: optimizing metabolic versatility and interactions with the environment. FEMS Microbiol Rev 34: 658-684.
    • (2010) FEMS Microbiol Rev - , vol.34 , pp. 658-684
    • Rojo, F.1
  • 176
    • 73849139244 scopus 로고    scopus 로고
    • SmQnr contributes to intrinsic resistance to quinolones in Stenotrophomonas maltophilia
    • Sanchez MB & Martinez JL (2010) SmQnr contributes to intrinsic resistance to quinolones in Stenotrophomonas maltophilia. Antimicrob Agents Ch 54: 580-581.
    • (2010) Antimicrob Agents Ch , vol.54 , pp. 580-581
    • Sanchez, M.B.1    Martinez, J.L.2
  • 177
    • 52949122901 scopus 로고    scopus 로고
    • Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants
    • Sanchez MB, Hernandez A, Rodriguez-Martinez JM, Martinez-Martinez L & Martinez JL (2008) Predictive analysis of transmissible quinolone resistance indicates Stenotrophomonas maltophilia as a potential source of a novel family of Qnr determinants. BMC Microbiol 8: 148.
    • (2008) BMC Microbiol , vol.8 , pp. 148
    • Sanchez, M.B.1    Hernandez, A.2    Rodriguez-Martinez, J.M.3    Martinez-Martinez, L.4    Martinez, J.L.5
  • 179
    • 0036841344 scopus 로고    scopus 로고
    • Cloning and characterization of SmeT, a repressor of the Stenotrophomonas maltophilia multidrug efflux pump SmeDEF
    • Sanchez P, Alonso A & Martinez JL (2002a) Cloning and characterization of SmeT, a repressor of the Stenotrophomonas maltophilia multidrug efflux pump SmeDEF. Antimicrob Agents Ch 46: 3386-3393.
    • (2002) Antimicrob Agents Ch , vol.46 , pp. 3386-3393
    • Sanchez, P.1    Alonso, A.2    Martinez, J.L.3
  • 182
    • 35648980556 scopus 로고    scopus 로고
    • Social cheating in Pseudomonas aeruginosa quorum sensing
    • Sandoz KM, Mitzimberg SM & Schuster M (2007) Social cheating in Pseudomonas aeruginosa quorum sensing. P Natl Acad Sci USA 104: 15876-15881.
    • (2007) P Natl Acad Sci USA , vol.104 , pp. 15876-15881
    • Sandoz, K.M.1    Mitzimberg, S.M.2    Schuster, M.3
  • 183
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Schlessinger J (2000) Cell signaling by receptor tyrosine kinases. Cell 103: 211-225.
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 185
    • 33646576218 scopus 로고    scopus 로고
    • Coexpression of virulence and fosfomycin susceptibility in Listeria: molecular basis of an antimicrobial in vitro-in vivo paradox
    • Scortti M, Lacharme-Lora L, Wagner M, Chico-Calero I, Losito P & Vazquez-Boland JA (2006) Coexpression of virulence and fosfomycin susceptibility in Listeria: molecular basis of an antimicrobial in vitro-in vivo paradox. Nat Med 12: 515-517.
    • (2006) Nat Med - , vol.12 , pp. 515-517
    • Scortti, M.1    Lacharme-Lora, L.2    Wagner, M.3    Chico-Calero, I.4    Losito, P.5    Vazquez-Boland, J.A.6
  • 186
    • 33751116307 scopus 로고    scopus 로고
    • Reporter metabolite analysis of transcriptional profiles of a Staphylococcus aureus strain with normal phenotype and its isogenic hemB mutant displaying the small-colony-variant phenotype
    • Seggewiss J, Becker K, Kotte O et al. (2006) Reporter metabolite analysis of transcriptional profiles of a Staphylococcus aureus strain with normal phenotype and its isogenic hemB mutant displaying the small-colony-variant phenotype. J Bacteriol 188: 7765-7777.
    • (2006) J Bacteriol , vol.188 , pp. 7765-7777
    • Seggewiss, J.1    Becker, K.2    Kotte, O.3
  • 187
    • 77955362067 scopus 로고    scopus 로고
    • Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis
    • Shcherbakov D, Akbergenov R, Matt T, Sander P, Andersson DI & Bottger EC (2010) Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis. Mol Microbiol 77: 830-840.
    • (2010) Mol Microbiol , vol.77 , pp. 830-840
    • Shcherbakov, D.1    Akbergenov, R.2    Matt, T.3    Sander, P.4    Andersson, D.I.5    Bottger, E.C.6
  • 188
    • 24944480029 scopus 로고    scopus 로고
    • Antibiotic resistance; a survival strategy
    • Sheldon AT Jr (2005) Antibiotic resistance: a survival strategy. Clin Lab Sci 18: 170-180.
    • (2005) Clin Lab Sci - , vol.18 , pp. 170-180
    • Sheldon Jr, A.T.1
  • 189
    • 0029130181 scopus 로고
    • Modulation of flagellar expression in Escherichia coli by acetyl phosphate and the osmoregulator OmpR
    • Shin S & Park C (1995) Modulation of flagellar expression in Escherichia coli by acetyl phosphate and the osmoregulator OmpR. J Bacteriol 177: 4696-4702.
    • (1995) J Bacteriol , vol.177 , pp. 4696-4702
    • Shin, S.1    Park, C.2
  • 190
    • 36148993342 scopus 로고    scopus 로고
    • Roles of the DNA binding proteins H-NS and StpA in homologous recombination and repair of bleomycin-induced damage in Escherichia coli
    • Shiraishi K, Ogata Y, Hanada K, Kano Y & Ikeda H (2007) Roles of the DNA binding proteins H-NS and StpA in homologous recombination and repair of bleomycin-induced damage in Escherichia coli. Genes Genet Syst 82: 433-439.
    • (2007) Genes Genet Syst , vol.82 , pp. 433-439
    • Shiraishi, K.1    Ogata, Y.2    Hanada, K.3    Kano, Y.4    Ikeda, H.5
  • 191
    • 27744562615 scopus 로고    scopus 로고
    • Adaptations of Pseudomonas aeruginosa to the cystic fibrosis lung environment can include deregulation of zwf, encoding glucose-6-phosphate dehydrogenase
    • Silo-Suh L, Suh SJ, Phibbs PV & Ohman DE (2005) Adaptations of Pseudomonas aeruginosa to the cystic fibrosis lung environment can include deregulation of zwf, encoding glucose-6-phosphate dehydrogenase. J Bacteriol 187: 7561-7568.
    • (2005) J Bacteriol , vol.187 , pp. 7561-7568
    • Silo-Suh, L.1    Suh, S.J.2    Phibbs, P.V.3    Ohman, D.E.4
  • 192
    • 33744814106 scopus 로고    scopus 로고
    • Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients
    • Smith EE, Buckley DG, Wu Z et al. (2006) Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. P Natl Acad Sci USA 103: 8487-8492.
    • (2006) P Natl Acad Sci USA , vol.103 , pp. 8487-8492
    • Smith, E.E.1    Buckley, D.G.2    Wu, Z.3
  • 193
    • 0020024790 scopus 로고
    • Successful treatment of experimental Escherichia coli infections in mice using phage: its general superiority over antibiotics
    • Smith HW & Huggins MB (1982) Successful treatment of experimental Escherichia coli infections in mice using phage: its general superiority over antibiotics. J Gen Microbiol 128: 307-318.
    • (1982) J Gen Microbiol - , vol.128 , pp. 307-318
    • Smith, H.W.1    Huggins, M.B.2
  • 194
    • 76049120271 scopus 로고    scopus 로고
    • Small RNA as global regulator of carbon catabolite repression in Pseudomonas aeruginosa
    • Sonnleitner E, Abdou L & Haas D (2009) Small RNA as global regulator of carbon catabolite repression in Pseudomonas aeruginosa. P Natl Acad Sci USA 106: 21866-21871.
    • (2009) P Natl Acad Sci USA , vol.106 , pp. 21866-21871
    • Sonnleitner, E.1    Abdou, L.2    Haas, D.3
  • 195
    • 42149158392 scopus 로고    scopus 로고
    • Control of bacterial transcription, translation and replication by (p)ppGpp
    • Srivatsan A & Wang JD (2008) Control of bacterial transcription, translation and replication by (p)ppGpp. Curr Opin Microbiol 11: 100-105.
    • (2008) Curr Opin Microbiol , vol.11 , pp. 100-105
    • Srivatsan, A.1    Wang, J.D.2
  • 197
    • 77954596827 scopus 로고    scopus 로고
    • Mutation of nfxB causes global changes in the physiology and metabolism of Pseudomonas aeruginosa
    • Stickland HG, Davenport PW, Lilley KS, Griffin JL & Welch M (2010) Mutation of nfxB causes global changes in the physiology and metabolism of Pseudomonas aeruginosa. J Proteome Res 9: 2957-2967.
    • (2010) J Proteome Res , vol.9 , pp. 2957-2967
    • Stickland, H.G.1    Davenport, P.W.2    Lilley, K.S.3    Griffin, J.L.4    Welch, M.5
  • 199
    • 0024805974 scopus 로고
    • A novel family of potentially mobile DNA elements encoding site-specific gene-integration functions: integrons
    • Stokes HW & Hall RM (1989) A novel family of potentially mobile DNA elements encoding site-specific gene-integration functions: integrons. Mol Microbiol 3: 1669-1683.
    • (1989) Mol Microbiol - , vol.3 , pp. 1669-1683
    • Stokes, H.W.1    Hall, R.M.2
  • 200
    • 0027254703 scopus 로고
    • Genome macrorestriction analysis of diversity and variability of Pseudomonas aeruginosa strains infecting cystic fibrosis patients
    • Struelens MJ, Schwam V, Deplano A & Baran D (1993) Genome macrorestriction analysis of diversity and variability of Pseudomonas aeruginosa strains infecting cystic fibrosis patients. J Clin Microbiol 31: 2320-2326.
    • (1993) J Clin Microbiol , vol.31 , pp. 2320-2326
    • Struelens, M.J.1    Schwam, V.2    Deplano, A.3    Baran, D.4
  • 201
    • 0028102175 scopus 로고
    • Investigation of ciprofloxacin penetration into Pseudomonas aeruginosa biofilms
    • Suci PA, Mittelman MW, Yu FP & Geesey GG (1994) Investigation of ciprofloxacin penetration into Pseudomonas aeruginosa biofilms. Antimicrob Agents Ch 38: 2125-2133.
    • (1994) Antimicrob Agents Ch , vol.38 , pp. 2125-2133
    • Suci, P.A.1    Mittelman, M.W.2    Yu, F.P.3    Geesey, G.G.4
  • 202
    • 73649133664 scopus 로고    scopus 로고
    • Phosphoproteomic analysis reveals the multiple roles of phosphorylation in pathogenic bacterium Streptococcus pneumoniae
    • Sun X, Ge F, Xiao CL, Yin XF, Ge R, Zhang LH & He QY (2009) Phosphoproteomic analysis reveals the multiple roles of phosphorylation in pathogenic bacterium Streptococcus pneumoniae. J Proteome Res 9: 275-282.
    • (2009) J Proteome Res , vol.9 , pp. 275-282
    • Sun, X.1    Ge, F.2    Xiao, C.L.3    Yin, X.F.4    Ge, R.5    Zhang, L.H.6    He, Q.Y.7
  • 203
    • 50249172242 scopus 로고    scopus 로고
    • Determination of antibiotic hypersensitivity among 4,000 single-gene-knockout mutants of Escherichia coli
    • Tamae C, Liu A, Kim K et al. (2008) Determination of antibiotic hypersensitivity among 4, 000 single-gene-knockout mutants of Escherichia coli. J Bacteriol 190: 5981-5988.
    • (2008) J Bacteriol , vol.190 , pp. 5981-5988
    • Tamae, C.1    Liu, A.2    Kim, K.3
  • 204
    • 77955293898 scopus 로고    scopus 로고
    • Role of PknB kinase in antibiotic resistance and virulence in community-acquired methicillin-resistant Staphylococcus aureus strain USA300
    • Tamber S, Schwartzman J & Cheung AL (2010) Role of PknB kinase in antibiotic resistance and virulence in community-acquired methicillin-resistant Staphylococcus aureus strain USA300. Infect Immun 78: 3637-3646.
    • (2010) Infect Immun , vol.78 , pp. 3637-3646
    • Tamber, S.1    Schwartzman, J.2    Cheung, A.L.3
  • 205
    • 0038323991 scopus 로고    scopus 로고
    • Mutation or overexpression of a terminal oxidase leads to a cell division defect and multiple antibiotic sensitivity in Pseudomonas aeruginosa
    • Tavankar GR, Mossialos D & Williams HD (2003) Mutation or overexpression of a terminal oxidase leads to a cell division defect and multiple antibiotic sensitivity in Pseudomonas aeruginosa. J Biol Chem 278: 4524-4530.
    • (2003) J Biol Chem , vol.278 , pp. 4524-4530
    • Tavankar, G.R.1    Mossialos, D.2    Williams, H.D.3
  • 206
    • 34250630499 scopus 로고    scopus 로고
    • Phenotypic characterization of clonal and nonclonal Pseudomonas aeruginosa strains isolated from lungs of adults with cystic fibrosis
    • Tingpej P, Smith L, Rose B et al. (2007) Phenotypic characterization of clonal and nonclonal Pseudomonas aeruginosa strains isolated from lungs of adults with cystic fibrosis. J Clin Microbiol 45: 1697-1704.
    • (2007) J Clin Microbiol , vol.45 , pp. 1697-1704
    • Tingpej, P.1    Smith, L.2    Rose, B.3
  • 207
    • 33745125702 scopus 로고    scopus 로고
    • ISCR elements: novel gene-capturing systems of the 21st century?
    • Toleman MA, Bennett PM & Walsh TR (2006) ISCR elements: novel gene-capturing systems of the 21st century? Microbiol Mol Biol R 70: 296-316.
    • (2006) Microbiol Mol Biol R - , vol.70 , pp. 296-316
    • Toleman, M.A.1    Bennett, P.M.2    Walsh, T.R.3
  • 208
    • 0019403305 scopus 로고
    • Bacterial persistence in leprosy
    • Toman K (1981) Bacterial persistence in leprosy. Int J Leprosy 49: 205-217.
    • (1981) Int J Leprosy , vol.49 , pp. 205-217
    • Toman, K.1
  • 209
    • 0038643232 scopus 로고    scopus 로고
    • Characterization of NorR protein, a multifunctional regulator of norA expression in Staphylococcus aureus
    • Truong-Bolduc QC, Zhang X & Hooper DC (2003) Characterization of NorR protein, a multifunctional regulator of norA expression in Staphylococcus aureus. J Bacteriol 185: 3127-3138.
    • (2003) J Bacteriol , vol.185 , pp. 3127-3138
    • Truong-Bolduc, Q.C.1    Zhang, X.2    Hooper, D.C.3
  • 211
    • 79952079593 scopus 로고    scopus 로고
    • Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection
    • Tuchscherr L, Medina E, Hussain M et al. (2011) Staphylococcus aureus phenotype switching: an effective bacterial strategy to escape host immune response and establish a chronic infection. EMBO Mol Med 3: 129-141.
    • (2011) EMBO Mol Med - , vol.3 , pp. 129-141
    • Tuchscherr, L.1    Medina, E.2    Hussain, M.3
  • 212
    • 0030065793 scopus 로고    scopus 로고
    • Staphylococcus aureus small colony variants are induced by the endothelial cell intracellular milieu
    • Vesga O, Groeschel MC, Otten MF, Brar DW, Vann JM & Proctor RA (1996) Staphylococcus aureus small colony variants are induced by the endothelial cell intracellular milieu. J Infect Dis 173: 739-742.
    • (1996) J Infect Dis , vol.173 , pp. 739-742
    • Vesga, O.1    Groeschel, M.C.2    Otten, M.F.3    Brar, D.W.4    Vann, J.M.5    Proctor, R.A.6
  • 213
    • 52449130017 scopus 로고    scopus 로고
    • Clinical impact of the over-expression of efflux pump in nonfermentative gram-negative bacilli, development of efflux pump inhibitors
    • Vila J & Martinez JL (2008) Clinical impact of the over-expression of efflux pump in nonfermentative gram-negative bacilli, development of efflux pump inhibitors. Curr Drug Targets 9: 797-807.
    • (2008) Curr Drug Targets , vol.9 , pp. 797-807
    • Vila, J.1    Martinez, J.L.2
  • 214
    • 0030872427 scopus 로고    scopus 로고
    • A site-directed Staphylococcus aureus hemB mutant is a small-colony variant which persists intracellularly
    • von Eiff C, Heilmann C, Proctor RA, Woltz C, Peters G & Gotz F (1997) A site-directed Staphylococcus aureus hemB mutant is a small-colony variant which persists intracellularly. J Bacteriol 179: 4706-4712.
    • (1997) J Bacteriol , vol.179 , pp. 4706-4712
    • von Eiff, C.1    Heilmann, C.2    Proctor, R.A.3    Woltz, C.4    Peters, G.5    Gotz, F.6
  • 215
    • 30744475750 scopus 로고    scopus 로고
    • Phenotype microarray profiling of Staphylococcus aureus menD and hemB mutants with the small-colony-variant phenotype
    • von Eiff C, McNamara P, Becker K et al. (2006) Phenotype microarray profiling of Staphylococcus aureus menD and hemB mutants with the small-colony-variant phenotype. J Bacteriol 188: 687-693.
    • (2006) J Bacteriol , vol.188 , pp. 687-693
    • von Eiff, C.1    McNamara, P.2    Becker, K.3
  • 216
    • 26444526660 scopus 로고
    • The soil as a source of microorganisms antagonistic to disease-producing bacteria
    • Waksman SA & Woodruff HB (1940) The soil as a source of microorganisms antagonistic to disease-producing bacteria. J Bacteriol 40: 581-600.
    • (1940) J Bacteriol , vol.40 , pp. 581-600
    • Waksman, S.A.1    Woodruff, H.B.2
  • 217
    • 33746493349 scopus 로고    scopus 로고
    • Tuberculosis chemotherapy: the influence of bacillary stress and damage response pathways on drug efficacy
    • Warner DF & Mizrahi V (2006) Tuberculosis chemotherapy: the influence of bacillary stress and damage response pathways on drug efficacy. Clin Microbiol Rev 19: 558-570.
    • (2006) Clin Microbiol Rev - , vol.19 , pp. 558-570
    • Warner, D.F.1    Mizrahi, V.2
  • 218
    • 39149112789 scopus 로고    scopus 로고
    • Regulation of the MtrC-MtrD-MtrE efflux-pump system modulates the in vivo fitness of Neisseria gonorrhoeae
    • Warner DM, Folster JP, Shafer WM & Jerse AE (2007) Regulation of the MtrC-MtrD-MtrE efflux-pump system modulates the in vivo fitness of Neisseria gonorrhoeae. J Infect Dis 196: 1804-1812.
    • (2007) J Infect Dis , vol.196 , pp. 1804-1812
    • Warner, D.M.1    Folster, J.P.2    Shafer, W.M.3    Jerse, A.E.4
  • 219
    • 0041894685 scopus 로고    scopus 로고
    • beta-Lactamase induction and cell wall recycling in gram-negative bacteria
    • Wiedemann B, Pfeifle D, Wiegand I & Janas E (1998) beta-Lactamase induction and cell wall recycling in gram-negative bacteria. Drug Resist Update 1: 223-226.
    • (1998) Drug Resist Update , vol.1 , pp. 223-226
    • Wiedemann, B.1    Pfeifle, D.2    Wiegand, I.3    Janas, E.4
  • 220
    • 7644241959 scopus 로고    scopus 로고
    • The role of H-NS in silencing F transfer gene expression during entry into stationary phase
    • Will WR, Lu J & Frost LS (2004) The role of H-NS in silencing F transfer gene expression during entry into stationary phase. Mol Microbiol 54: 769-782.
    • (2004) Mol Microbiol , vol.54 , pp. 769-782
    • Will, W.R.1    Lu, J.2    Frost, L.S.3
  • 221
    • 63749104134 scopus 로고    scopus 로고
    • Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules
    • Williams P & Camara M (2009) Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules. Curr Opin Microbiol 12: 182-191.
    • (2009) Curr Opin Microbiol - , vol.12 , pp. 182-191
    • Williams, P.1    Camara, M.2
  • 222
    • 0025815884 scopus 로고
    • Isolation and characterization of catabolite repression control mutants of Pseudomonas aeruginosa PAO
    • Wolff JA, MacGregor CH, Eisenberg RC & Phibbs PV Jr (1991) Isolation and characterization of catabolite repression control mutants of Pseudomonas aeruginosa PAO. J Bacteriol 173: 4700-4706.
    • (1991) J Bacteriol , vol.173 , pp. 4700-4706
    • Wolff, J.A.1    MacGregor, C.H.2    Eisenberg, R.C.3    Phibbs Jr, P.V.4
  • 223
    • 77953631468 scopus 로고    scopus 로고
    • (p)ppGpp and drug resistance
    • Wu J, Long Q & Xie J (2010) (p)ppGpp and drug resistance. J Cell Physiol 224: 300-304.
    • (2010) J Cell Physiol , vol.224 , pp. 300-304
    • Wu, J.1    Long, Q.2    Xie, J.3
  • 224
  • 225
    • 77954609311 scopus 로고    scopus 로고
    • Iron homeostasis affects antibiotic-mediated cell death in Pseudomonas species
    • Yeom J, Imlay JA & Park W (2010) Iron homeostasis affects antibiotic-mediated cell death in Pseudomonas species. J Biol Chem 285: 22689-22695.
    • (2010) J Biol Chem , vol.285 , pp. 22689-22695
    • Yeom, J.1    Imlay, J.A.2    Park, W.3
  • 226
    • 77955953679 scopus 로고    scopus 로고
    • Meta-transcriptomic analysis of the response of river biofilms to pharmaceutical products using anonymous DNA microarrays
    • Yergeau E, Lawrence JR, Waiser MJ, Korber DR & Greer CW (2010) Meta-transcriptomic analysis of the response of river biofilms to pharmaceutical products using anonymous DNA microarrays. Appl Environ Microb 26: 5432-5439.
    • (2010) Appl Environ Microb , vol.26 , pp. 5432-5439
    • Yergeau, E.1    Lawrence, J.R.2    Waiser, M.J.3    Korber, D.R.4    Greer, C.W.5
  • 227
    • 69949111853 scopus 로고    scopus 로고
    • Swarming of Pseudomonas aeruginosa is controlled by a broad spectrum of transcriptional regulators, including MetR
    • Yeung AT, Torfs EC, Jamshidi F, Bains M, Wiegand I, Hancock RE & Overhage J (2009) Swarming of Pseudomonas aeruginosa is controlled by a broad spectrum of transcriptional regulators, including MetR. J Bacteriol 191: 5592-5602.
    • (2009) J Bacteriol , vol.191 , pp. 5592-5602
    • Yeung, A.T.1    Torfs, E.C.2    Jamshidi, F.3    Bains, M.4    Wiegand, I.5    Hancock, R.E.6    Overhage, J.7
  • 228
    • 79551494258 scopus 로고    scopus 로고
    • The sensor kinase CbrA is a global regulator that modulates metabolism, virulence, and antibiotic resistance in Pseudomonas aeruginosa
    • Yeung AT, Bains M & Hancock RE (2011) The sensor kinase CbrA is a global regulator that modulates metabolism, virulence, and antibiotic resistance in Pseudomonas aeruginosa. J Bacteriol 193: 918-931.
    • (2011) J Bacteriol , vol.193 , pp. 918-931
    • Yeung, A.T.1    Bains, M.2    Hancock, R.E.3
  • 230
    • 34447571924 scopus 로고    scopus 로고
    • Antibiotics as signalling molecules
    • Yim G, Wang HH & Davies J (2007) Antibiotics as signalling molecules. Philos T R Soc B 362: 1195-1200.
    • (2007) Philos T R Soc B , vol.362 , pp. 1195-1200
    • Yim, G.1    Wang, H.H.2    Davies, J.3
  • 231
    • 0027488699 scopus 로고
    • Mechanism of efficient elimination of protein D2 in outer membrane of imipenem-resistant Pseudomonas aeruginosa
    • Yoneyama H & Nakae T (1993) Mechanism of efficient elimination of protein D2 in outer membrane of imipenem-resistant Pseudomonas aeruginosa. Antimicrob Agents Ch 37: 2385-2390.
    • (1993) Antimicrob Agents Ch , vol.37 , pp. 2385-2390
    • Yoneyama, H.1    Nakae, T.2
  • 232
    • 0035682220 scopus 로고    scopus 로고
    • Role of the crc gene in catabolic repression of the Pseudomonas putida GPo1 alkane degradation pathway
    • Yuste L & Rojo F (2001) Role of the crc gene in catabolic repression of the Pseudomonas putida GPo1 alkane degradation pathway. J Bacteriol 183: 6197-6206.
    • (2001) J Bacteriol , vol.183 , pp. 6197-6206
    • Yuste, L.1    Rojo, F.2
  • 233
    • 46049083393 scopus 로고    scopus 로고
    • Involvement of a novel efflux system in biofilm-specific resistance to antibiotics
    • Zhang L & Mah TF (2008) Involvement of a novel efflux system in biofilm-specific resistance to antibiotics. J Bacteriol 190: 4447-4452.
    • (2008) J Bacteriol , vol.190 , pp. 4447-4452
    • Zhang, L.1    Mah, T.F.2
  • 234
    • 0029616734 scopus 로고
    • Cystic fibrosis; genotypic and phenotypic variations
    • Zielenski J & Tsui LC (1995) Cystic fibrosis: genotypic and phenotypic variations. Annu Rev Genet 29: 777-807.
    • (1995) Annu Rev Genet - , vol.29 , pp. 777-807
    • Zielenski, J.1    Tsui, L.C.2
  • 235
    • 65249143794 scopus 로고    scopus 로고
    • Role of Acinetobacter baylyi Crc in catabolite repression of enzymes for aromatic compound catabolism
    • Zimmermann T, Sorg T, Siehler SY & Gerischer U (2009) Role of Acinetobacter baylyi Crc in catabolite repression of enzymes for aromatic compound catabolism. J Bacteriol 191: 2834-2842.
    • (2009) J Bacteriol , vol.191 , pp. 2834-2842
    • Zimmermann, T.1    Sorg, T.2    Siehler, S.Y.3    Gerischer, U.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.