-
1
-
-
77954244776
-
Endothelial activation and circulating markers of endothelial activation in kidney disease
-
Rabelink, T. J., de Boer, H. C., and, van Zonneveld, A. J., (2010) Endothelial activation and circulating markers of endothelial activation in kidney disease. Nat. Rev. Nephrol. 6, 404-414.
-
(2010)
Nat. Rev. Nephrol.
, vol.6
, pp. 404-414
-
-
Rabelink, T.J.1
De Boer, H.C.2
Van Zonneveld, A.J.3
-
2
-
-
34748914299
-
Evolving functions of endothelial cells in inflammation
-
DOI 10.1038/nri2171, PII NRI2171
-
Pober, J. S., and, Sessa, W. C., (2007) Evolving functions of endothelial cells in inflammation. Nat. Rev. Immunol. 7, 803-815. (Pubitemid 47480307)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.10
, pp. 803-815
-
-
Pober, J.S.1
Sessa, W.C.2
-
3
-
-
79960822733
-
-
In Progress in Inflamation Research, vol. (Parnharm, M., ed.). pp., Springer, Basel
-
Molema, G., (2010) Endothelial dysfunction and inflammation. In Progress in Inflamation Research, vol. 2 (, Parnharm, M., ed.). pp. 14-35, Springer, Basel.
-
(2010)
Endothelial Dysfunction and Inflammation
, vol.2
, pp. 14-35
-
-
Molema, G.1
-
4
-
-
33846798106
-
Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms
-
DOI 10.1161/01.RES.0000255691.76142.4a, PII 0000301220070202000004
-
Aird, W. C., (2007) Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. Circ. Res. 100, 158-173. (Pubitemid 46208717)
-
(2007)
Circulation Research
, vol.100
, Issue.2
, pp. 158-173
-
-
Aird, W.C.1
-
5
-
-
33846849237
-
Phenotypic heterogeneity of the endothelium: II
-
Aird, W. C., (2007) Phenotypic heterogeneity of the endothelium: II. Representative vascular beds. Circ. Res. 100, 174-190.
-
(2007)
Representative Vascular Beds. Circ. Res.
, vol.100
, pp. 174-190
-
-
Aird, W.C.1
-
6
-
-
77953234568
-
Heterogeneity in endothelial responsiveness to cytokines, molecular causes, and pharmacological consequences
-
Molema, G., (2010) Heterogeneity in endothelial responsiveness to cytokines, molecular causes, and pharmacological consequences. Semin. Thromb. Hemost. 36, 246-264.
-
(2010)
Semin. Thromb. Hemost.
, vol.36
, pp. 246-264
-
-
Molema, G.1
-
7
-
-
42049090782
-
Regulation of arterial-venous differences in tumor necrosis factor responsiveness of endothelial cells by anatomic context
-
DOI 10.2353/ajpath.2008.070603
-
Liu, M., Kluger, M. S., D'Alessio, A., Garcia-Cardena, G., and, Pober, J. S., (2008) Regulation of arterial-venous differences in tumor necrosis factor responsiveness of endothelial cells by anatomic context. Am. J. Pathol. 172, 1088-1099. (Pubitemid 351520005)
-
(2008)
American Journal of Pathology
, vol.172
, Issue.4
, pp. 1088-1099
-
-
Liu, M.1
Kluger, M.S.2
D'Alessio, A.3
Garcia-Cardena, G.4
Pober, J.S.5
-
8
-
-
57749202435
-
Microvascular endothelial cell heterogeneity: General concepts and pharmacological consequences for anti-angiogenic therapy of cancer
-
Langenkamp, E., and, Molema, G., (2009) Microvascular endothelial cell heterogeneity: general concepts and pharmacological consequences for anti-angiogenic therapy of cancer. Cell Tissue Res. 335, 205-222.
-
(2009)
Cell Tissue Res.
, vol.335
, pp. 205-222
-
-
Langenkamp, E.1
Molema, G.2
-
9
-
-
11844270511
-
Molecular pathways of endothelial cell activation for (targeted) pharmacological intervention of chronic inflammatory diseases
-
DOI 10.2174/1570161052773898
-
Kuldo, J. M., Ogawara, K. I., Werner, N., Asgeirsdottir, S. A., Kamps, J. A., et al. (2005) Molecular pathways of endothelial cell activation for (targeted) pharmacological intervention of chronic inflammatory diseases. Curr. Vasc. Pharmacol. 3, 11-39. (Pubitemid 40089525)
-
(2005)
Current Vascular Pharmacology
, vol.3
, Issue.1
, pp. 11-39
-
-
Kuldo, J.M.1
Ogawara, K.I.2
Werner, N.3
Asgeirsdottir, S.A.4
Kamps, J.A.A.M.5
Kok, R.J.6
Molema, G.7
-
10
-
-
78049338489
-
Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery (review)
-
Huang, R. B., Mocherla, S., Heslinga, M. J., Charoenphol, P., and, Eniola-Adefeso, O., (2010) Dynamic and cellular interactions of nanoparticles in vascular-targeted drug delivery (review). Mol. Membr. Biol. 27, 190-205.
-
(2010)
Mol. Membr. Biol.
, vol.27
, pp. 190-205
-
-
Huang, R.B.1
Mocherla, S.2
Heslinga, M.J.3
Charoenphol, P.4
Eniola-Adefeso, O.5
-
11
-
-
79960205109
-
Targeted drug delivery to the tumor neovasculature: Concepts, advances, and challenges
-
In, Chapter 25 (Figg, W. D. and Folkman, J., eds). pp., Springer Verlarg, New York
-
Molema, G., (2008) Targeted drug delivery to the tumor neovasculature: concepts, advances, and challenges. In Angiogenesis: An Integrative Approach From Science to Medicine, Chapter 25 (, Figg, W. D., and, Folkman, J., eds). pp. 283-297, Springer Verlarg, New York.
-
(2008)
Angiogenesis: An Integrative Approach from Science to Medicine
, pp. 283-297
-
-
Molema, G.1
-
12
-
-
77953289569
-
-
In Liposome Technology, vol. (Gregoriadis, G., ed). pp., Informa Healthcare, New York
-
Kamps, J. A. A. M., and, Molema, G., (2007) Targeting liposomes to endothelial cells in inflammatory diseases. In Liposome Technology, vol. 3 (, Gregoriadis, G., ed). pp. 127-150, Informa Healthcare, New York.
-
(2007)
Targeting Liposomes to Endothelial Cells in Inflammatory Diseases
, vol.3
, pp. 127-150
-
-
Kamps, J.A.A.M.1
Molema, G.2
-
13
-
-
68049110523
-
Shock-induced stress induces loss of microvascular endothelial Tie2 in the kidney which is not associated with reduced glomerular barrier function
-
van Meurs, M., Kurniati, N. F., Wulfert, F. M., Asgeirsdottir, S. A., de Graaf, I. A., et al. (2009) Shock-induced stress induces loss of microvascular endothelial Tie2 in the kidney which is not associated with reduced glomerular barrier function. Am. J. Physiol. Renal Physiol. 297, F272-281.
-
(2009)
Am. J. Physiol. Renal Physiol.
, vol.297
-
-
Van Meurs, M.1
Kurniati, N.F.2
Wulfert, F.M.3
Asgeirsdottir, S.A.4
De Graaf, I.A.5
-
14
-
-
51649085622
-
Polymeric particles conjugated with a ligand to VCAM-1 exhibit selective, avid, and focal adhesion to sites of atherosclerosis
-
Deosarkar, S. P., Malgor, R., Fu, J., Kohn, L. D., Hanes, J., et al. (2008) Polymeric particles conjugated with a ligand to VCAM-1 exhibit selective, avid, and focal adhesion to sites of atherosclerosis. Biotechnol. Bioeng. 101, 400-407.
-
(2008)
Biotechnol. Bioeng.
, vol.101
, pp. 400-407
-
-
Deosarkar, S.P.1
Malgor, R.2
Fu, J.3
Kohn, L.D.4
Hanes, J.5
-
15
-
-
33947159556
-
Targeted delivery of antibody conjugated liposomal drug carriers to rat myocardial infarction
-
DOI 10.1002/bit.21233
-
Scott, R. C., Wang, B., Nallamothu, R., Pattillo, C. B., Perez-Liz, G., et al. (2007) Targeted delivery of antibody conjugated liposomal drug carriers to rat myocardial infarction. Biotechnol. Bioeng. 96, 795-802. (Pubitemid 46395947)
-
(2007)
Biotechnology and Bioengineering
, vol.96
, Issue.4
, pp. 795-802
-
-
Scott, R.C.1
Wang, B.2
Nallamothu, R.3
Pattillo, C.B.4
Perez-Liz, G.5
Issekutz, A.6
Del Valle, L.7
Wood, G.C.8
Kiani, M.F.9
-
16
-
-
34347211015
-
Site-specific inhibition of glomerulonephritis progression by targeted delivery of dexamethasone to glomerular endothelium
-
DOI 10.1124/mol.107.034140
-
Asgeirsdottir, S. A., Kamps, J. A., Bakker, H. I., Zwiers, P. J., Heeringa, P., et al. (2007) Site-specific inhibition of glomerulonephritis progression by targeted delivery of dexamethasone to glomerular endothelium. Mol. Pharmacol. 72, 121-131. (Pubitemid 46998531)
-
(2007)
Molecular Pharmacology
, vol.72
, Issue.1
, pp. 121-131
-
-
Asgeirsdottir, S.A.1
Kamps, J.A.A.M.2
Bakker, H.I.3
Zwiers, P.J.4
Heeringa, P.5
Van Der Weide, K.6
Van Goor, H.7
Petersen, A.H.8
Morselt, H.9
Moorlag, H.E.10
Steenbergen, E.11
Kallenberg, C.G.12
Molema, G.13
-
17
-
-
33646381864
-
Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis
-
DOI 10.1002/art.21719
-
Koning, G. A., Schiffelers, R. M., Wauben, M. H., Kok, R. J., Mastrobattista, E., et al. (2006) Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis. Arthritis Rheum. 54, 1198-1208. (Pubitemid 43672932)
-
(2006)
Arthritis and Rheumatism
, vol.54
, Issue.4
, pp. 1198-1208
-
-
Koning, G.A.1
Schiffelers, R.M.2
Wauben, M.H.M.3
Kok, R.J.4
Mastrobattista, E.5
Molema, G.6
Ten Hagen, T.L.M.7
Storm, G.8
-
18
-
-
33846025384
-
Accumulation of liposome with Sialyl Lewis X to inflammation and tumor region: Application to in vivo bio-imaging
-
DOI 10.1016/j.bbrc.2006.12.060, PII S0006291X06026805
-
Hirai, M., Minematsu, H., Kondo, N., Oie, K., Igarashi, K., et al. (2007) Accumulation of liposome with Sialyl Lewis X to inflammation and tumor region: application to in vivo bio-imaging. Biochem. Biophys. Res. Commun. 353, 553-558. (Pubitemid 46048704)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.353
, Issue.3
, pp. 553-558
-
-
Hirai, M.1
Minematsu, H.2
Kondo, N.3
Oie, K.4
Igarashi, K.5
Yamazaki, N.6
-
19
-
-
0035984573
-
Lipid-mediated delivery of oligonucleotide to pulmonary endothelium
-
Ma, Z., Zhang, J., Alber, S., Dileo, J., Negishi, Y., et al. (2002) Lipid-mediated delivery of oligonucleotide to pulmonary endothelium. Am. J. Respir. Cell Mol. Biol. 27, 151-159. (Pubitemid 34780794)
-
(2002)
American Journal of Respiratory Cell and Molecular Biology
, vol.27
, Issue.2
, pp. 151-159
-
-
Ma, Z.1
Zhang, J.2
Alber, S.3
Dileo, J.4
Negishi, Y.5
Stolz, D.6
Watkins, S.7
Huang, L.8
Pitt, B.9
Li, S.10
-
20
-
-
38349094193
-
Early organ-specific endothelial activation during hemorrhagic shock and resuscitation
-
van Meurs, M., Wulfert, F. M., Knol, A. J., De Haes, A., Houwertjes, M., et al. (2008) Early organ-specific endothelial activation during hemorrhagic shock and resuscitation. Shock. 29, 291-299.
-
(2008)
Shock
, vol.29
, pp. 291-299
-
-
Van Meurs, M.1
Wulfert, F.M.2
Knol, A.J.3
De Haes, A.4
Houwertjes, M.5
-
21
-
-
0036846648
-
Cellular handling of a dexamethasone-anti-E-selectin immunoconjugate by activated endothelial cells: Comparison with free dexamethasone
-
DOI 10.1023/A:1020769716288
-
Kok, R. J., Everts, M., Asgeirsdottir, S. A., Meijer, D. K., and, Molema, G., (2002) Cellular handling of a dexamethasone-anti-E-selectin immunoconjugate by activated endothelial cells: comparison with free dexamethasone. Pharm. Res. 19, 1730-1735. (Pubitemid 35305526)
-
(2002)
Pharmaceutical Research
, vol.19
, Issue.11
, pp. 1730-1735
-
-
Kok, R.J.1
Everts, M.2
Asgeirsdottir, S.A.3
Meijer, D.K.F.4
Molema, G.5
-
22
-
-
0037080027
-
Selective intracellular delivery of dexamethasone into activated endothelial cells using an E-selectin-directed immunoconjugate
-
Everts, M., Kok, R. J., Asgeirsdottir, S. A., Melgert, B. N., Moolenaar, T. J., et al. (2002) Selective intracellular delivery of dexamethasone into activated endothelial cells using an E-selectin-directed immunoconjugate. J. Immunol. 168, 883-889. (Pubitemid 34049592)
-
(2002)
Journal of Immunology
, vol.168
, Issue.2
, pp. 883-889
-
-
Everts, M.1
Kok, R.J.2
Asgeirsdottir, S.A.3
Melgert, B.N.4
Moolenaar, T.J.M.5
Koning, G.A.6
Van Luyn, M.J.A.7
Meijer, D.K.F.8
Molema, G.9
-
23
-
-
0037261231
-
In vitro cellular handling and in vivo targeting of E-selectin-directed immunoconjugates and immunoliposomes used for drug delivery to inflamed endothelium
-
DOI 10.1023/A:1022298725165
-
Everts, M., Koning, G. A., Kok, R. J., Asgeirsdottir, S. A., Vestweber, D., et al. (2003) In vitro cellular handling and in vivo targeting of E-selectin-directed immunoconjugates and immunoliposomes used for drug delivery to inflamed endothelium. Pharm. Res. 20, 64-72. (Pubitemid 36152919)
-
(2003)
Pharmaceutical Research
, vol.20
, Issue.1
, pp. 64-72
-
-
Everts, M.1
Koning, G.A.2
Kok, R.J.3
Asgeirsdottir, S.A.4
Vestweber, D.5
Meijer, D.K.F.6
Storm, G.7
Molema, G.8
-
24
-
-
84928854056
-
Adhesion molecule-1 and vascular cell adhesion molecule-1
-
In (Aird, W., ed.). pp., Cambridge University press, New York
-
Muro, S., (2007) Adhesion molecule-1 and vascular cell adhesion molecule-1. In Endothelial Biomedicine (, Aird, W., ed.). pp. 1058-1070, Cambridge University press, New York.
-
(2007)
Endothelial Biomedicine
, pp. 1058-1070
-
-
Muro, S.1
-
25
-
-
0034644684
-
Expression of antisense to integrin subunit beta 3 inhibits microvascular endothelial cell capillary tube formation in fibrin
-
Dallabrida, S. M., De Sousa, M. A., and, Farrell, D. H., (2000) Expression of antisense to integrin subunit beta 3 inhibits microvascular endothelial cell capillary tube formation in fibrin. J. Biol. Chem. 275, 32281-32288.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 32281-32288
-
-
Dallabrida, S.M.1
De Sousa, M.A.2
Farrell, D.H.3
-
26
-
-
0028362876
-
Requirement of vascular integrin alpha v beta 3 for angiogenesis
-
Brooks, P. C., Clark, R. A., and, Cheresh, D. A., (1994) Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science. 264, 569-571.
-
(1994)
Science.
, vol.264
, pp. 569-571
-
-
Brooks, P.C.1
Clark, R.A.2
Cheresh, D.A.3
-
27
-
-
0346311614
-
Development of vasculature targeting strategies for the treatment of cancer and chronic inflammatory diseases
-
DOI 10.1016/S1387-2656(02)08007-9
-
Schraa, A. J., Everts, M., Kok, R. J., Asgeirsdottir, S. A., Meijer, D. K., et al. (2002) Development of vasculature targeting strategies for the treatment of cancer and chronic inflammatory diseases. Biotechnol. Annu. Rev. 8, 133-165. (Pubitemid 41081519)
-
(2002)
Biotechnology Annual Review
, vol.8
, pp. 133-165
-
-
Schraa, A.J.1
Everts, M.2
Kok, R.J.3
Asgeirsdottir, S.A.4
Meijer, D.K.F.5
De Leij, L.F.M.H.6
Molema, G.7
-
28
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel, D. P., (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 116, 281-297.
-
(2004)
Cell.
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
29
-
-
77957361864
-
Targeting microRNAs in cancer: Rationale, strategies and challenges
-
Garzon, R., Marcucci, G., and, Croce, C. M., (2010) Targeting microRNAs in cancer: rationale, strategies and challenges. Nat. Rev. Drug. Discov. 9, 775-789.
-
(2010)
Nat. Rev. Drug. Discov.
, vol.9
, pp. 775-789
-
-
Garzon, R.1
Marcucci, G.2
Croce, C.M.3
-
30
-
-
65749088084
-
SiRNA vs. shRNA: Similarities and differences
-
Rao, D. D., Vorhies, J. S., Senzer, N., and, Nemunaitis, J., (2009) siRNA vs. shRNA: similarities and differences. Adv. Drug Deliv. Rev. 61, 746-759.
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, pp. 746-759
-
-
Rao, D.D.1
Vorhies, J.S.2
Senzer, N.3
Nemunaitis, J.4
-
31
-
-
58749104364
-
The promises and pitfalls of RNA-interference-based therapeutics
-
Castanotto, D., and, Rossi, J. J., (2009) The promises and pitfalls of RNA-interference-based therapeutics. Nature. 457, 426-433.
-
(2009)
Nature.
, vol.457
, pp. 426-433
-
-
Castanotto, D.1
Rossi, J.J.2
-
32
-
-
77955419350
-
RNA interference for therapy in the vascular endothelium
-
Kaufmann, J., Ahrens, K., and, Santel, A., (2010) RNA interference for therapy in the vascular endothelium. Microvasc. Res. 80, 286-293.
-
(2010)
Microvasc. Res.
, vol.80
, pp. 286-293
-
-
Kaufmann, J.1
Ahrens, K.2
Santel, A.3
-
33
-
-
38449100230
-
A protocol for designing siRNAs with high functionality and specificity
-
DOI 10.1038/nprot.2007.278, PII NPROT.2007.278
-
Birmingham, A., Anderson, E., Sullivan, K., Reynolds, A., Boese, Q., et al. (2007) A protocol for designing siRNAs with high functionality and specificity. Nat. Protoc. 2, 2068-2078. (Pubitemid 351565844)
-
(2007)
Nature Protocols
, vol.2
, Issue.9
, pp. 2068-2078
-
-
Birmingham, A.1
Anderson, E.2
Sullivan, K.3
Reynolds, A.4
Boese, Q.5
Leake, D.6
Karpilow, J.7
Khvorova, A.8
-
34
-
-
35348911812
-
Brothers in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies
-
DOI 10.2353/ajpath.2007.070120
-
Bhindi, R., Fahmy, R. G., Lowe, H. C., Chesterman, C. N., Dass, C. R., et al. (2007) Brothers in arms: DNA enzymes, short interfering RNA, and the emerging wave of small-molecule nucleic acid-based gene-silencing strategies. Am. J. Pathol. 171, 1079-1088. (Pubitemid 47582883)
-
(2007)
American Journal of Pathology
, vol.171
, Issue.4
, pp. 1079-1088
-
-
Bhindi, R.1
Fahmy, R.G.2
Lowe, H.C.3
Chesterman, C.N.4
Dass, C.R.5
Cairns, M.J.6
Saravolac, E.G.7
Sun, L.-Q.8
Khachigian, L.M.9
-
35
-
-
77956453939
-
Cancer therapy via modulation of micro RNA levels: A promising future
-
Kota, S. K., and, Balasubramanian, S., (2010) Cancer therapy via modulation of micro RNA levels: a promising future. Drug. Discov. Today. 15, 733-740.
-
(2010)
Drug. Discov. Today.
, vol.15
, pp. 733-740
-
-
Kota, S.K.1
Balasubramanian, S.2
-
36
-
-
77955384669
-
MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis
-
Anand, S., Majeti, B. K., Acevedo, L. M., Murphy, E. A., Mukthavaram, R., et al. (2010) MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Nat. Med. 16, 909-914.
-
(2010)
Nat. Med.
, vol.16
, pp. 909-914
-
-
Anand, S.1
Majeti, B.K.2
Acevedo, L.M.3
Murphy, E.A.4
Mukthavaram, R.5
-
37
-
-
0031042534
-
Tumor vascular endothelium: Barrier or target in tumor directed drug delivery and immunotherapy
-
DOI 10.1023/A:1012038930172
-
Molema, G., de Leij, L. F., and, Meijer, D. K., (1997) Tumor vascular endothelium: barrier or target in tumor directed drug delivery and immunotherapy. Pharm. Res. 14, 2-10. (Pubitemid 27113308)
-
(1997)
Pharmaceutical Research
, vol.14
, Issue.1
, pp. 2-10
-
-
Molema, G.1
De Leij, L.F.M.H.2
Meijer, D.K.F.3
-
38
-
-
12644302177
-
Immunotargeting of liposomes to activated vascular endothelial cells: A strategy for site-selective delivery in the cardiovascular system
-
DOI 10.1073/pnas.94.16.8795
-
Spragg, D. D., Alford, D. R., Greferath, R., Larsen, C. E., Lee, K. D., et al. (1997) Immunotargeting of liposomes to activated vascular endothelial cells: a strategy for site-selective delivery in the cardiovascular system. Proc. Natl. Acad. Sci. USA. 94, 8795-8800. (Pubitemid 27335119)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.16
, pp. 8795-8800
-
-
Spragg, D.D.1
Alford, D.R.2
Greferath, R.3
Larsen, C.E.4
Lee, K.-D.5
Gurtner, G.C.6
Cybulsky, M.I.7
Tosi, P.F.8
Nicolau, C.9
Gimbrone Jr., M.A.10
-
39
-
-
0035168461
-
Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature
-
DOI 10.1186/ar327
-
Gerlag, D. M., Borges, E., Tak, P. P., Ellerby, H. M., Bredesen, D. E., et al. (2001) Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature. Arthritis Res. 3, 357-361. (Pubitemid 33077115)
-
(2001)
Arthritis Research
, vol.3
, Issue.6
, pp. 357-361
-
-
Gerlag, D.M.1
Borges, E.2
Tak, P.P.3
Ellerby, H.M.4
Bredesen, D.E.5
Pasqualini, R.6
Ruoslahti, E.7
Firestein, G.S.8
-
40
-
-
0142116193
-
Slow intracellular trafficking of catalase nanoparticles targeted to ICAM-1 protects endothelial cells from oxidative stress
-
Muro, S., Cui, X., Gajewski, C., Murciano, J. C., Muzykantov, V. R., etal. (2003) Slow intracellular trafficking of catalase nanoparticles targeted to ICAM-1 protects endothelial cells from oxidative stress. Am. J. Physiol. Cell Physiol. 285, C1339-1347. (Pubitemid 37296311)
-
(2003)
American Journal of Physiology - Cell Physiology
, vol.285
, Issue.5
-
-
Muro, S.1
Cui, X.2
Gajewski, C.3
Murciano, J.-C.4
Muzykantov, V.R.5
Koval, M.6
-
41
-
-
22144496816
-
Cell-specific targeting of lipid-based carriers for ODN and DNA
-
DOI 10.1081/LPR-64961
-
Bartsch, M., Weeke-Klimp, A. H., Meijer, D. K., Scherphof, G. L., and, Kamps, J. A., (2005) Cell-specific targeting of lipid-based carriers for ODN and DNA. J. Liposome Res. 15, 59-92. (Pubitemid 40976307)
-
(2005)
Journal of Liposome Research
, vol.15
, Issue.1-2
, pp. 59-92
-
-
Bartsch, M.1
Weeke-Klimp, A.H.2
Meijer, D.K.F.3
Scherphof, G.L.4
Kamps, J.A.A.M.5
-
42
-
-
33746228119
-
Knocking down Disease with siRNAs
-
DOI 10.1016/j.cell.2006.07.007, PII S0092867406009007
-
Dykxhoorn, D. M., and, Lieberman, J., (2006) Knocking down disease with siRNAs. Cell 126, 231-235. (Pubitemid 44092975)
-
(2006)
Cell
, vol.126
, Issue.2
, pp. 231-235
-
-
Dykxhoorn, D.M.1
Lieberman, J.2
-
43
-
-
57349134691
-
Chemical modification of siRNAs for in vivo use
-
DOI 10.1089/oli.2008.0164
-
Behlke, M. A., (2008) Chemical modification of siRNAs for in vivo use. Oligonucleotides. 18, 305-319. (Pubitemid 352791344)
-
(2008)
Oligonucleotides
, vol.18
, Issue.4
, pp. 305-319
-
-
Behlke, M.A.1
-
44
-
-
77953683945
-
Non-viral nanosystems for systemic siRNA delivery
-
David, S., Pitard, B., Benoit, J. P., and, Passirani, C., (2010) Non-viral nanosystems for systemic siRNA delivery. Pharmacol. Res. 62, 100-114.
-
(2010)
Pharmacol. Res.
, vol.62
, pp. 100-114
-
-
David, S.1
Pitard, B.2
Benoit, J.P.3
Passirani, C.4
-
45
-
-
57749193734
-
Targeted delivery of therapeutics to endothelium
-
Simone, E., Ding, B. S., and, Muzykantov, V., (2009) Targeted delivery of therapeutics to endothelium. Cell Tissue Res. 335, 283-300.
-
(2009)
Cell Tissue Res.
, vol.335
, pp. 283-300
-
-
Simone, E.1
Ding, B.S.2
Muzykantov, V.3
-
46
-
-
0037088992
-
Targeting tumors with non-viral gene delivery systems
-
DOI 10.1016/S1359-6446(02)02243-2, PII S1359644602022432
-
Ogris, M., and, Wagner, E., (2002) Targeting tumors with non-viral gene delivery systems. Drug Discov. Today 7, 479-485. (Pubitemid 34532575)
-
(2002)
Drug Discovery Today
, vol.7
, Issue.8
, pp. 479-485
-
-
Ogris, M.1
Wagner, E.2
-
47
-
-
38549103632
-
Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles
-
Li, S. D., Chono, S., and, Huang, L., (2008) Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles. J. Controlled Release 126, 77-84.
-
(2008)
J. Controlled Release
, vol.126
, pp. 77-84
-
-
Li, S.D.1
Chono, S.2
Huang, L.3
-
48
-
-
4644323971
-
pH-Sensitive PEG lipids containing orthoester linkers: New potential tools for nonviral gene delivery
-
DOI 10.1016/j.jconrel.2004.07.016, PII S0168365904003311
-
Masson, C., Garinot, M., Mignet, N., Wetzer, B., Mailhe, P., et al. (2004) pH-sensitive PEG lipids containing orthoester linkers: new potential tools for nonviral gene delivery. J. Controlled Release 99, 423-434. (Pubitemid 39296911)
-
(2004)
Journal of Controlled Release
, vol.99
, Issue.3
, pp. 423-434
-
-
Masson, C.1
Garinot, M.2
Mignet, N.3
Wetzer, B.4
Mailhe, P.5
Scherman, D.6
Bessodes, M.7
-
49
-
-
78650564093
-
Targeted delivery of RNAi therapeutics for cancer therapy
-
Li, J., and, Huang, L., (2010) Targeted delivery of RNAi therapeutics for cancer therapy. Nanomedicine (Lond) 5, 1483-1486.
-
(2010)
Nanomedicine (Lond)
, vol.5
, pp. 1483-1486
-
-
Li, J.1
Huang, L.2
-
50
-
-
0036372307
-
Stabilized plasmid-lipid particles: A systemic gene therapy vector
-
DOI 10.1016/S0076-6879(02)46046-6, 3, Gene Therapy Methods
-
Fenske, D. B., MacLachlan, I., and, Cullis, P. R., (2002) Stabilized plasmid-lipid particles: a systemic gene therapy vector. Methods Enzymol. 346, 36-71. (Pubitemid 41103130)
-
(2002)
Methods in Enzymology
, vol.346
, pp. 36-71
-
-
Fenske, D.B.1
MacLachlan, I.2
Cullis, P.R.3
-
51
-
-
77955214948
-
The role of carrier size in the pharmacodynamics of antisense and siRNA oligonucleotides
-
Huang, L., Sullenger, B., and, Juliano, R., (2011) The role of carrier size in the pharmacodynamics of antisense and siRNA oligonucleotides. J.Drug Target. 18, 567-574.
-
(2011)
J.Drug Target.
, vol.18
, pp. 567-574
-
-
Huang, L.1
Sullenger, B.2
Juliano, R.3
-
52
-
-
33645309040
-
Advanced drug delivery systems that target the vascular endothelium
-
Ding, B. S., Dziubla, T., Shuvaev, V. V., Muro, S., and, Muzykantov, V. R., (2006) Advanced drug delivery systems that target the vascular endothelium. Mol. Interv. 6, 98-112.
-
(2006)
Mol. Interv.
, vol.6
, pp. 98-112
-
-
Ding, B.S.1
Dziubla, T.2
Shuvaev, V.V.3
Muro, S.4
Muzykantov, V.R.5
-
53
-
-
0023694565
-
Conditions for the occurrence of large near-wall excesses of small particles during blood flow
-
Eckstein, E. C., Tilles, A. W., and, Millero, F. J. III, (1988) Conditions for the occurrence of large near-wall excesses of small particles during blood flow. Microvasc. Res. 36, 31-39.
-
(1988)
Microvasc. Res.
, vol.36
, pp. 31-39
-
-
Eckstein, E.C.1
Tilles, A.W.2
Millero III, F.J.3
-
54
-
-
72149100143
-
Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers
-
Charoenphol, P., Huang, R. B., and, Eniola-Adefeso, O., (2010) Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers. Biomaterials. 31, 1392-1402.
-
(2010)
Biomaterials.
, vol.31
, pp. 1392-1402
-
-
Charoenphol, P.1
Huang, R.B.2
Eniola-Adefeso, O.3
-
55
-
-
48349116380
-
Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers
-
Muro, S., Garnacho, C., Champion, J. A., Leferovich, J., Gajewski, C., et al. (2008) Control of endothelial targeting and intracellular delivery of therapeutic enzymes by modulating the size and shape of ICAM-1-targeted carriers. Mol. Ther. 16, 1450-1458.
-
(2008)
Mol. Ther.
, vol.16
, pp. 1450-1458
-
-
Muro, S.1
Garnacho, C.2
Champion, J.A.3
Leferovich, J.4
Gajewski, C.5
-
56
-
-
70449089802
-
Strategies for targeted nonviral delivery of siRNAs in vivo
-
Kim, S. S., Garg, H., Joshi, A., and, Manjunath, N., (2009) Strategies for targeted nonviral delivery of siRNAs in vivo. Trends Mol. Med. 15, 491-500.
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 491-500
-
-
Kim, S.S.1
Garg, H.2
Joshi, A.3
Manjunath, N.4
-
57
-
-
0030822608
-
Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells
-
DOI 10.1073/pnas.94.21.11681
-
Kamps, J. A., Morselt, H. W., Swart, P. J., Meijer, D. K., and, Scherphof, G. L., (1997) Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells. Proc. Natl. Acad. Sci. USA 94, 11681-11685. (Pubitemid 27451058)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.21
, pp. 11681-11685
-
-
Kamps, J.A.A.M.1
Morselt, H.W.M.2
Swart, P.J.3
Meijer, D.K.F.4
Scherphof, G.L.5
-
58
-
-
3042696866
-
Endothelial endocytic pathways: Gates for vascular drug delivery
-
DOI 10.2174/1570161043385736
-
Muro, S., Koval, M., and, Muzykantov, V., (2004) Endothelial endocytic pathways: gates for vascular drug delivery. Curr. Vasc. Pharmacol. 2, 281-299. (Pubitemid 38855034)
-
(2004)
Current Vascular Pharmacology
, vol.2
, Issue.3
, pp. 281-299
-
-
Muro, S.1
Koval, M.2
Muzykantov, V.3
-
59
-
-
65549137133
-
Targeted delivery of nucleic-acid-based therapeutics to the pulmonary circulation
-
Kuruba, R., Wilson, A., Gao, X., and, Li, S., (2009) Targeted delivery of nucleic-acid-based therapeutics to the pulmonary circulation. AAPS J. 11, 23-30.
-
(2009)
AAPS J.
, vol.11
, pp. 23-30
-
-
Kuruba, R.1
Wilson, A.2
Gao, X.3
Li, S.4
-
60
-
-
33746883220
-
A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium
-
DOI 10.1038/sj.gt.3302777, PII 3302777
-
Santel, A., Aleku, M., Keil, O., Endruschat, J., Esche, V., et al. (2006) A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium. Gene Ther. 13, 1222-1234. (Pubitemid 44184716)
-
(2006)
Gene Therapy
, vol.13
, Issue.16
, pp. 1222-1234
-
-
Santel, A.1
Aleku, M.2
Keil, O.3
Endruschat, J.4
Esche, V.5
Fisch, G.6
Dames, S.7
Loffler, K.8
Fechtner, M.9
Arnold, W.10
Giese, K.11
Klippel, A.12
Kaufmann, J.13
-
61
-
-
0034597146
-
Rapid transport of internalized P-selectin to late endosomes and the TGN: Roles in regulating cell surface expression and recycling to secretory granules
-
Straley, K. S., and, Green, S. A., (2000) Rapid transport of internalized P-selectin to late endosomes and the TGN: roles in regulating cell surface expression and recycling to secretory granules. J. Cell Biol. 151, 107-116.
-
(2000)
J. Cell Biol.
, vol.151
, pp. 107-116
-
-
Straley, K.S.1
Green, S.A.2
-
62
-
-
0038067968
-
A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1
-
DOI 10.1242/jcs.00367
-
Muro, S., Wiewrodt, R., Thomas, A., Koniaris, L., Albelda, S. M., et al. (2003) A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1. J. Cell Sci. 116, 1599-1609. (Pubitemid 36527505)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.8
, pp. 1599-1609
-
-
Muro, S.1
Wiewrodt, R.2
Thomas, A.3
Koniaris, L.4
Albelda, S.M.5
Muzykantov, V.R.6
Koval, M.7
-
63
-
-
0027320072
-
+-ATPases: Versatile proton pumps participating in constitutive and specialized functions of eukaryotic cells
-
Gluck, S. L., (1993) The vacuolar H(+)-ATPases: versatile proton pumps participating in constitutive and specialized functions of eukaryotic cells. Int. Rev. Cytol. 137C, 105-137. (Pubitemid 23204715)
-
(1993)
International Review of Cytology
, vol.137 C
, pp. 105-137
-
-
Gluck, S.L.1
-
64
-
-
28844460780
-
Intracellular trafficking of nonviral vectors
-
DOI 10.1038/sj.gt.3302592, PII 3302592
-
Medina-Kauwe, L. K., Xie, J., and, Hamm-Alvarez, S., (2005) Intracellular trafficking of nonviral vectors. Gene Ther. 12, 1734-1751. (Pubitemid 41760286)
-
(2005)
Gene Therapy
, vol.12
, Issue.24
, pp. 1734-1751
-
-
Medina-Kauwe, L.K.1
Xie, J.2
Hamm-Alvarez, S.3
-
65
-
-
77953293784
-
Targeted SAINT-O-Somes for improved intracellular delivery of siRNA and cytotoxic drugs into endothelial cells
-
Adrian, J. E., Morselt, H. W., Suss, R., Barnert, S., Kok, J. W., et al. (2010) Targeted SAINT-O-Somes for improved intracellular delivery of siRNA and cytotoxic drugs into endothelial cells. J. Controlled Release 144, 341-349.
-
(2010)
J. Controlled Release
, vol.144
, pp. 341-349
-
-
Adrian, J.E.1
Morselt, H.W.2
Suss, R.3
Barnert, S.4
Kok, J.W.5
-
66
-
-
0029949266
-
Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
-
DOI 10.1021/bi9602019
-
Xu, Y., and, Szoka, F. C. Jr. , (1996) Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry 35, 5616-5623. (Pubitemid 26143656)
-
(1996)
Biochemistry
, vol.35
, Issue.18
, pp. 5616-5623
-
-
Xu, Y.1
Szoka Jr., F.C.2
-
67
-
-
0029964866
-
Mechanism of oligonucleotide release from cationic liposomes
-
DOI 10.1073/pnas.93.21.11493
-
Zelphati, O., and, Szoka, F. C. Jr. , (1996) Mechanism of oligonucleotide release from cationic liposomes. Proc. Natl. Acad. Sci. USA 93, 11493-11498. (Pubitemid 26347149)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.21
, pp. 11493-11498
-
-
Zelphati, O.1
Szoka Jr., F.C.2
-
68
-
-
33845190449
-
Cationic lipids, lipoplexes and intracellular delivery of genes
-
DOI 10.1016/j.jconrel.2006.06.024, PII S0168365906003191
-
Wasungu, L., and, Hoekstra, D., (2006) Cationic lipids, lipoplexes and intracellular delivery of genes. J. Controlled Release 116, 255-264. (Pubitemid 44854274)
-
(2006)
Journal of Controlled Release
, vol.116
, Issue.2 SPEC. ISS.
, pp. 255-264
-
-
Wasungu, L.1
Hoekstra, D.2
-
69
-
-
34250187101
-
pH-Sensitive liposomes - Principle and application in cancer therapy
-
DOI 10.1211/jpp.59.4.0001
-
Karanth, H., and, Murthy, R. S., (2007) pH-sensitive liposomes-principle and application in cancer therapy. J. Pharm. Pharmacol. 59, 469-483. (Pubitemid 47051120)
-
(2007)
Journal of Pharmacy and Pharmacology
, vol.59
, Issue.4
, pp. 469-483
-
-
Karanth, H.1
Murthy, R.S.R.2
-
70
-
-
0242414440
-
Chloride Accumulation and Swelling in Endosomes Enhances DNA Transfer by Polyamine-DNA Polyplexes
-
DOI 10.1074/jbc.M308643200
-
Sonawane, N. D., Szoka, F. C. Jr. , and, Verkman, A. S., (2003) Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J. Biol. Chem. 278, 44826-44831. (Pubitemid 37377241)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.45
, pp. 44826-44831
-
-
Sonawane, N.D.1
Szoka Jr., F.C.2
Verkman, A.S.3
-
71
-
-
0023447252
-
Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
-
Felgner, P. L., Gadek, T. R., Holm, M., Roman, R., Chan, H. W., et al. (1987) Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl. Acad. Sci. USA 84, 7413-7417.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 7413-7417
-
-
Felgner, P.L.1
Gadek, T.R.2
Holm, M.3
Roman, R.4
Chan, H.W.5
-
72
-
-
72949119713
-
Lipidic systems for in vivo siRNA delivery
-
Wu, S. Y., and, McMillan, N. A., (2009) Lipidic systems for in vivo siRNA delivery. AAPS J. 11, 639-652.
-
(2009)
AAPS J.
, vol.11
, pp. 639-652
-
-
Wu, S.Y.1
McMillan, N.A.2
-
73
-
-
67249096677
-
Nonviral methods for siRNA delivery
-
Gao, K., and, Huang, L., (2009) Nonviral methods for siRNA delivery. Mol. Pharm. 6, 651-658.
-
(2009)
Mol. Pharm.
, vol.6
, pp. 651-658
-
-
Gao, K.1
Huang, L.2
-
74
-
-
14544298301
-
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
-
Schiffelers, R. M., Ansari, A., Xu, J., Zhou, Q., Tang, Q., et al. (2004) Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res. 32, e149.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Schiffelers, R.M.1
Ansari, A.2
Xu, J.3
Zhou, Q.4
Tang, Q.5
-
75
-
-
35548994599
-
Serum insensitive, intranuclear protein delivery by the multipurpose cationic lipid Saint-2
-
DOI 10.1016/j.jconrel.2007.08.014, PII S0168365907004166
-
van der, Gun, B. T., Monami, A., Laarmann, S., Rasko, T., Slaska-Kiss, K., et al. (2007) Serum insensitive, intranuclear protein delivery by the multipurpose cationic lipid SAINT-2. J. Controlled Release 123, 228-238. (Pubitemid 350017779)
-
(2007)
Journal of Controlled Release
, vol.123
, Issue.3
, pp. 228-238
-
-
Van Der Gun, B.T.F.1
Monami, A.2
Laarmann, S.3
Rasko, T.4
Slaska-Kiss, K.5
Weinhold, E.6
Wasserkort, R.7
De Leij, L.F.M.H.8
Ruiters, M.H.J.9
Kiss, A.10
McLaughlin, P.M.J.11
-
76
-
-
72449163929
-
Targeted transfection increases siRNA uptake and gene silencing of primary endothelial cells in vitro-a quantitative study
-
Asgeirsdottir, S. A., Talman, E. G., de Graaf, I. A., Kamps, J. A., Satchell, S. C., et al. (2010) Targeted transfection increases siRNA uptake and gene silencing of primary endothelial cells in vitro-a quantitative study. J. Controlled Release 141, 241-251.
-
(2010)
J. Controlled Release
, vol.141
, pp. 241-251
-
-
Asgeirsdottir, S.A.1
Talman, E.G.2
De Graaf, I.A.3
Kamps, J.A.4
Satchell, S.C.5
-
77
-
-
41149118880
-
Esel liposomes
-
DOI 10.1152/ajprenal.00391.2007
-
Asgeirsdottir, S. A., Zwiers, P. J., Morselt, H. W., Moorlag, H. E., Bakker, H. I., et al. (2008) Inhibition of proinflammatory genes in anti-GBM glomerulonephritis by targeted dexamethasone-loaded AbEsel liposomes. Am. J. Physiol. Renal Physiol. 294, F554-F561. (Pubitemid 351442225)
-
(2008)
American Journal of Physiology - Renal Physiology
, vol.294
, Issue.3
-
-
Asgeirsdottir, S.A.1
Zwiers, P.J.2
Morselt, H.W.3
Moorlag, H.E.4
Bakker, H.I.5
Heeringa, P.6
Kok, J.W.7
Kallenberg, C.G.M.8
Molema, G.9
Kamps, J.A.A.M.10
-
78
-
-
77955914314
-
Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies
-
de, et al
-
de Graaf, I. A., Olinga, P., de Jager, M. H., Merema, M. T., de, Kanter, R., et al. (2010) Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies. Nat. Protoc. 5, 1540-1551.
-
(2010)
Nat. Protoc.
, vol.5
, pp. 1540-1551
-
-
De Graaf, I.A.1
Olinga, P.2
De Jager, M.H.3
Merema, M.T.4
Kanter, R.5
-
79
-
-
77955113615
-
Targeted gene silencing using RGD-labeled chitosan nanoparticles
-
Han, H. D., Mangala, L. S., Lee, J. W., Shahzad, M. M., Kim, H. S., et al. (2010) Targeted gene silencing using RGD-labeled chitosan nanoparticles. Clin. Cancer Res. 16, 3910-3922.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 3910-3922
-
-
Han, H.D.1
Mangala, L.S.2
Lee, J.W.3
Shahzad, M.M.4
Kim, H.S.5
-
80
-
-
57149086661
-
Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression
-
Aleku, M., Fisch, G., Mopert, K., Keil, O., Arnold, W., et al. (2008) Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression. Cancer Res. 68, 9788-9798.
-
(2008)
Cancer Res
, vol.68
, pp. 9788-9798
-
-
Aleku, M.1
Fisch, G.2
Mopert, K.3
Keil, O.4
Arnold, W.5
-
81
-
-
33644839698
-
SiRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway
-
Miyawaki-Shimizu, K., Predescu, D., Shimizu, J., Broman, M., Predescu, S., et al. (2006) siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway. Am. J. Physiol. Lung Cell Mol. Physiol. 290, L405-413.
-
(2006)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.290
-
-
Miyawaki-Shimizu, K.1
Predescu, D.2
Shimizu, J.3
Broman, M.4
Predescu, S.5
-
82
-
-
50949095169
-
Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes
-
Auguste, D. T., Furman, K., Wong, A., Fuller, J., Armes, S. P., et al. (2008) Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes. J. Controlled Release 130, 266-274.
-
(2008)
J. Controlled Release
, vol.130
, pp. 266-274
-
-
Auguste, D.T.1
Furman, K.2
Wong, A.3
Fuller, J.4
Armes, S.P.5
|