Targeted delivery of nucleic acid-based therapeutics to the pulmonary circulation

AAPS Journal

Volumn 11, Issue 1, 2009, Pages 23-30

  Kuruba, Ramalinga ^a   Wilson, Annette ^a   Gao, Xiang ^a   Li, Song ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Delivery; Endothelial cells; Genes; Lung; Oligonucleotides; Pulmonary circulation; SiRNA; Targeting

Indexed keywords

1,2 DIOLEOYL 3 DIMETHYLAMMONIOPROPANE; ADENOVIRUS VECTOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LIPID; LIPOSOME; LISINOPRIL; NUCLEIC ACID; OLIGONUCLEOTIDE; POLYETHYLENEIMINE; UNCLASSIFIED DRUG; UROKINASE; VIRUS VECTOR;

COMPLEX FORMATION; DRUG DELIVERY SYSTEM; DRUG TARGETING; DRUG UPTAKE; GENE TRANSFER; GENETIC REGULATION; HUMAN; HYPERTENSION; LIPOSOMAL DELIVERY; LUNG CIRCULATION; LUNG ENDOTHELIUM; LUNG FIBROSIS; MACROMOLECULE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PHAGE DISPLAY; REVIEW; SINGLE DRUG DOSE; SURFACE PROPERTY; VIRAL GENE DELIVERY SYSTEM;

ADMINISTRATION, INHALATION; ANIMALS; ANTIGENS, SURFACE; CATIONS; DEPENDOVIRUS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOTHELIAL CELLS; GENE THERAPY; GENETIC VECTORS; HUMANS; INJECTIONS, INTRAVENOUS; LIPIDS; LIPOSOMES; LUNG; MICE; NUCLEIC ACIDS; OLIGONUCLEOTIDES; PEPTIDES; POLYMERS; PULMONARY CIRCULATION; RNA, SMALL INTERFERING;

EID: 65549137133     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-008-9073-0     Document Type: Review

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