Siva is an apoptosis-selective p53 target gene important for neuronal cell death

Cell Death and Differentiation

Volumn 14, Issue 7, 2007, Pages 1374-1385

  Jacobs, S B R ^a   Basak, S ^a   Murray, J I ^a,b   Pathak, N ^a   Attardi, L D ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS REGULATORY PROTEIN; CASPASE 8; PROTEIN BID; PROTEIN P53; SIVA PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CELL CYCLE ARREST; CEREBELLUM; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENE IDENTIFICATION; MICROARRAY ANALYSIS; MOUSE; NERVE CELL MEMBRANE; NERVE CELL NECROSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UNINDEXED SEQUENCE; UPREGULATION;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BRAIN DISEASES; CASPASE 8; CELL MEMBRANE; CELLS, CULTURED; CEREBELLUM; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, KNOCKOUT; NERVE DEGENERATION; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 34250705250     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/sj.cdd.4402128     Document Type: Article

References (43)

1. Vousden KH, Lu X. Live or let die: The cell's response to p53. Nat Rev Cancer 2002; 2: 594-604.
2. Morrison RS, Kinoshita Y, Johnson MD, Guo W, Garden GA. p53-dependent cell death signaling in neurons. Neurochem Res 2003; 28: 15-27.
3. Bae BI, Xu H, Igarashi S, Fujimuro M, Agrawal N, Taya Y et al. p53 mediates cellular dysfuntion and behavioral abnormalities in Huntington's disease. Neuron 2005; 47: 29-41.
4. Culmsee C, Mattson MP. p53 in neuronal apoptosis. Biochem Biophys Res Commun 2005; 331: 761-777.
5. Duan W, Zhu X, Ladenheim B, Yu QS, Guo Z, Oyler J et al. p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism. Ann Neurol 2002; 52: 597-606.
6. Culmsee C, Zhu X, Yu QS, Chan SL, Camandola S, Guo Z et al. A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide. J Neurochem 2001; 77: 220-228.
7. Leker RR, Aharonowiz M, Greig NH, Ovadia H. The role of p53-induced apoptosis in cerebral ischemia: Effects of the p53 inhibitor pifithrin alpha. Exp Neurol 2004; 187: 478-486.
8. Chao C, Saito S, Kang J, Anderson CW, Appella E, Xu Y. p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage. EMBO J 2000; 19: 4967-4975.
9. Johnson TM, Hammond EM, Giaccia A, Attardi LD. The p53QS transactivation-deficient mutant shows stress-specific apoptotic activity and induces embryonic lethality. Nat Genet 2005; 37 145-152.
10. Ihrie RA, Reczek E, Homer JS, Khachatrian L, Sage J, Jacks T et al. Perp is a mediator of p53-dependent apoptosis in diverse cell types. Curr Biol 2003; 13: 1985-1990.
11. Jeffers JR, Parganas E, Lee Y, Yang C, Wang J, Brennan J et al. Puma is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell 2003; 4: 321-328.
12. McCurrach ME, Connor TM, Knudson CM, Korsmeyer SJ, Lowe SW. Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proc Natl Acad Sci USA 1997; 94: 2345-2349.
13. Shibue T, Takeda K, Oda E, Tanaka H, Murasawa H, Takaoka A et al. Integral role of Noxa in p53-mediated apoptotic response. Genes Dev 2003; 17: 2233-2238.
14. Villunger A, Michalak EM, Coultas L, Mullauer F, Bock G, Ausserlechner MJ et al. p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 2003; 302: 1036-1038.
15. Attardi LD, Reczek EE, Cosmas C, Demicco EG, McCurrach ME, Lowe SW et al. PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family. Genes Dev 2000; 14: 704-718.
16. Lowe SW, Ruley HE. Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis. Genes Dev 1993; 7: 535-545.
17. Debbas M, White E. Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev 1993; 7: 546-554.
18. Soengas MS, Alarcon RM, Yoshida H, Giaccia AJ, Hakern R, Mak TW et al. Apal-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science 1999; 284: 156-159.
19. Prasad KV, Ao Z, Yoon Y, Wu MX, Rizk M, Jacquot S et al. CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein. Proc Natl Acad Sci USA 1997; 94: 6346-6351.
20. Masse K, Dabernat S, Bourbon PM, Larou M, Amrein L, Barraud P et al. Characterization of the nm23-M2, nm23-M3 and nm23-M4 mouse genes: comparison with their human orthologs. Gene 2002; 296: 87-97.
21. Mikesch JH, Buerger H, Simon R, Brandt B. Decay-accelerating factor (CD55): A versatile acting molecule in human malignancies. Biochim Biophys Acta 2006; 1766: 42-52.
22. Fortin A, MacLaurin JG, Arbour N, Cregan SP, Kushwaha N, Callaghan SM et al. The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1. J Biol Chem 2004; 279 28706-28714.
23. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 1991; 352: 345-347.
24. Enokido Y, Araki T, Tanaka K, Aizawa S, Hatanaka H. Involvement of p53 in DNA strand break-induced apoptosis in postmitotic CNS neurons. Eur J Neurosci 1996; 8: 1812-1821.
25. Cory S, Adams JM. The Bcl2 family: Regulators of the cellular life-or-death switch. Nat Rev Cancer 2002; 2: 647-656.
26. Py B, Slomianny C, Auberger P, Petit PX, Benichou S. Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway. J Immunol 2004; 172: 4008-4017.
27. Xue L, Chu F, Cheng Y, Sun X, Borthakur A, Ramarao M et al. Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis. Proc Natl Acad Sci USA 2002; 99 6925-6930.
28. Herzog KH, Chong MJ, Kapsetaki M, Morgan JI, McKinnon PJ. Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science 1998; 280: 1089-1091.
29. Plesnila N, Zinkel S, Le DA, Amin-Hanjani S, Wu Y, Qiu J et al. BID mediates neuronal cell death after oxygen/glucose deprivation and focal cerebral ischemia. Proc Natl Acad Sci USA 2001; 98: 15318-15323.
30. Fortin A, Cregan SP, MacLaurin JG, Kushwaha N, Hickman ES, Thompson CS et al. APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death. J Cell Biol 2001; 155: 207-216.
31. Xiang H, Kinoshita Y, Knudson CM, Korsmeyer SJ, Schwartzkroin PA, Morrison RS. Bax involvement in p53-mediated neuronal cell death. J Neurosci 1998; 18: 1363-1373.
32. Spinicelli S, Nocentini G, Ronchetti S, Krausz LT, Bianchini R, Riccardi C. GITR interacts with the pro-opoptotic protein Siva and induces apoptosis. Cell Death Differ 2002; 9: 1382-1384.
33. Chu F, Barkinge J, Hawkins S, Gudi R, Salgia R, Kanteti PV. Expression of Siva-1 protein or its putative amphipathic helical region enhances cisplatin-induced apoptosis in breast cancer cells: Effect of elevated levels of BCL-2. Cancer Res 2005; 65: 5301-5309.
34. Semont A, Nowak EB, Silva Lages C, Mathieu C, Mouthon MA, May E et al. Involvement of p53 and Fas/CD95 in murine neural progenitor cell response to ionizing irradiation. Oncogene 2004; 23: 8497-8508.
35. Finnberg N, Gruber JJ, Fei P, Rudolph D, Bric A, Kim SH et al. DR5 knockout mice are compromised in radiation-induced apoptosis. Mol Cell Biol 2005; 25: 2000-2013.
36. Michalak E, Villunger A, Erlacher M, Strasser A. Death squads enlisted by the tumour suppressor p53. Biochem Biophys Res Commun 2005; 331: 786-798.
37. Yin XM, Wang K, Gross A, Zhao Y, Zinkel S, Klocke B et al. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature 1999; 400: 886-891.
38. Mattson MP. Apoptosis in neurodegenerative disorders. Nat Rev Mol Cell Biol 2000; 1: 120-129.
39. Chung CH, Parker JS, Karaca G, Wu J, Funkhouser WK, Moore D et al. Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression. Cancer Cell 2004; 5: 489-500.
40. Attardi LD, Lowe SW, Brugarolas J, Jacks T. Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO J 1996; 15: 3693-3701.
41. Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependant and -independent mechanisms. Science 1999; 286: 1358-1362.
42. Rubinson DA, Dillon CP, Kwiatkowski AV, Sievers C, Yang L, Kopinja J et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 2003; 33: 401-406.
43. Vogelmann R, Nelson WJ. Fractionation of the epithelial apical junctional complex: Reassessment of protein distributions in different substructures. Mol Biol Cell 2005; 16: 701-716.