-
1
-
-
0001007610
-
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
-
Martin GR. 1981. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci. USA 78:7634-38
-
(1981)
Proc. Natl. Acad. Sci. USA
, vol.78
, pp. 7634-76338
-
-
Martin, G.R.1
-
2
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson JA, Itskovitz-Eldor J, Shapiro SS, WaknitzMA, Swiergiel JJ, et al. 1998. Embryonic stem cell lines derived from human blastocysts. Science 282:1145-47
-
(1998)
Science
, vol.282
, pp. 1145-11447
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
-
3
-
-
34447527158
-
Derivation of pluripotent epiblast stem cells from mammalian embryos
-
DOI 10.1038/nature05950, PII NATURE05950
-
Brons IG, Smithers LE, Trotter MW, Rugg-Gunn P, Sun B, et al. 2007. Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature 448:191-95 (Pubitemid 47067373)
-
(2007)
Nature
, vol.448
, Issue.7150
, pp. 191-195
-
-
Brons, I.G.M.1
Smithers, L.E.2
Trotter, M.W.B.3
Rugg-Gunn, P.4
Sun, B.5
Chuva De Sousa Lopes, S.M.6
Howlett, S.K.7
Clarkson, A.8
Ahrlund-Richter, L.9
Pedersen, R.A.10
Vallier, L.11
-
4
-
-
34447528757
-
New cell lines from mouse epiblast share defining features with human embryonic stem cells
-
DOI 10.1038/nature05972, PII NATURE05972
-
Tesar PJ, Chenoweth JG, Brook FA,DaviesTJ, Evans EP, et al. 2007. New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature 448:196-99 (Pubitemid 47067378)
-
(2007)
Nature
, vol.448
, Issue.7150
, pp. 196-199
-
-
Tesar, P.J.1
Chenoweth, J.G.2
Brook, F.A.3
Davies, T.J.4
Evans, E.P.5
Mack, D.L.6
Gardner, R.L.7
McKay, R.D.G.8
-
5
-
-
0032506231
-
Derivation of pluripotent stem cells from cultured human primordial germ cells
-
DOI 10.1073/pnas.95.23.13726
-
Shamblott MJ, Axelman J, Wang S, Bugg EM, Littlefield JW, et al. 1998. Derivation of pluripotent stem cells from cultured human primordial germ cells. Proc. Natl. Acad. Sci. USA 95:13726-31 (Pubitemid 28523040)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.23
, pp. 13726-13731
-
-
Shamblott, M.J.1
Axelman, J.2
Wang, S.3
Bugg, E.M.4
Littlefield, J.W.5
Donovan, P.J.6
Blumenthal, P.D.7
Huggins, G.R.8
Gearhart, J.D.9
-
6
-
-
33747195353
-
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
-
DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
-
Takahashi K, Yamanaka S. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126:663-76 (Pubitemid 44233629)
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
7
-
-
36248966518
-
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
-
DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, et al. 2007. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:861-72 (Pubitemid 350138099)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
8
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, Antosiewicz-Bourget J, Frane JL, et al. 2007. Induced pluripotent stem cell lines derived from human somatic cells. Science 318:1917-20
-
(2007)
Science
, vol.318
, pp. 1917-19120
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
-
9
-
-
3042744026
-
A role for chemistry in stem cell biology
-
DOI 10.1038/nbt987
-
Ding S, Schultz PG. 2004. A role for chemistry in stem cell biology. Nat. Biotechnol. 22:833-40 (Pubitemid 38886601)
-
(2004)
Nature Biotechnology
, vol.22
, Issue.7
, pp. 833-840
-
-
Ding, S.1
Schultz, P.G.2
-
10
-
-
43749104249
-
A chemical approach to stem-cell biology and regenerative medicine
-
DOI 10.1038/nature07042, PII NATURE07042
-
Xu Y, Shi Y, Ding S. 2008. A chemical approach to stem-cell biology and regenerative medicine. Nature 453:338-44 (Pubitemid 351693140)
-
(2008)
Nature
, vol.453
, Issue.7193
, pp. 338-344
-
-
Xu, Y.1
Shi, Y.2
Ding, S.3
-
11
-
-
39149129085
-
Stem Cells and Drug Discovery: The Beginning of a New Era?
-
DOI 10.1016/j.cell.2008.02.010, PII S0092867408002183
-
Rubin LL. 2008. Stem cells and drug discovery: the beginning of a new era? Cell 132:549-52 (Pubitemid 351253700)
-
(2008)
Cell
, vol.132
, Issue.4
, pp. 549-552
-
-
Rubin, L.L.1
-
12
-
-
65349105337
-
Using small molecules to great effect in stem cell differentiation
-
Zaret KS. 2009. Using small molecules to great effect in stem cell differentiation. Cell Stem Cell 4:373-74
-
(2009)
Cell Stem Cell
, vol.4
, pp. 373-374
-
-
Zaret, K.S.1
-
13
-
-
62949220231
-
Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells
-
Feng B, Ng JH,Heng JC, Ng HH. 2009. Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. Cell Stem Cell 4:301-12
-
(2009)
Cell Stem Cell
, vol.4
, pp. 301-312
-
-
Feng, B.1
Ng Jhheng, J.C.2
Ng, H.H.3
-
14
-
-
72749089194
-
Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming
-
Li W, Ding S. 2010. Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming. Trends Pharmacol. Sci. 31:36-45
-
(2010)
Trends Pharmacol. Sci.
, vol.31
, pp. 36-45
-
-
Li, W.1
Ding, S.2
-
15
-
-
37749027080
-
Small molecules in stem cell self-renewal and differentiation
-
SchugarRC, Robbins PD,Deasy BM. 2008. Small molecules in stem cell self-renewal and differentiation. Gene Ther. 15:126-35
-
(2008)
Gene Ther.
, vol.15
, pp. 126-135
-
-
Schugar, R.C.1
Robbins, P.D.2
Deasy, B.M.3
-
16
-
-
75749099851
-
Controlling destiny through chemistry: Small-molecule regulators of cell fate
-
Firestone AJ, Chen JK. 2010. Controlling destiny through chemistry: small-molecule regulators of cell fate. ACS Chem. Biol. 5:15-34
-
(2010)
ACS Chem. Biol.
, vol.5
, pp. 15-34
-
-
Firestone, A.J.1
Chen, J.K.2
-
17
-
-
63049090064
-
A fresh look at iPS cells
-
Yamanaka S. 2009. A fresh look at iPS cells. Cell 137:13-17
-
(2009)
Cell
, vol.137
, pp. 13-17
-
-
Yamanaka, S.1
-
18
-
-
56549127713
-
Guidelines and techniques for the generation of induced pluripotent stem cells
-
Maherali N, Hochedlinger K. 2008. Guidelines and techniques for the generation of induced pluripotent stem cells. Cell Stem Cell 3:595-605
-
(2008)
Cell Stem Cell
, vol.3
, pp. 595-605
-
-
Maherali, N.1
Hochedlinger, K.2
-
19
-
-
60849132723
-
Broader implications of defining standards for the pluripotency of iPSCs
-
author reply 202
-
Daley GQ, Lensch MW, Jaenisch R, Meissner A, Plath K, Yamanaka S. 2009. Broader implications of defining standards for the pluripotency of iPSCs. Cell Stem Cell 4:200-1; author reply 202
-
(2009)
Cell Stem Cell
, vol.4
, pp. 200-1
-
-
Daley, G.Q.1
Lensch, M.W.2
Jaenisch, R.3
Meissner, A.4
Plath, K.5
Yamanaka, S.6
-
20
-
-
70450285340
-
Technical challenges in using human induced pluripotent stem cells to model disease
-
Saha K, Jaenisch R. 2009. Technical challenges in using human induced pluripotent stem cells to model disease. Cell Stem Cell 5:584-95
-
(2009)
Cell Stem Cell
, vol.5
, pp. 584-595
-
-
Saha, K.1
Jaenisch, R.2
-
21
-
-
44349103591
-
A Combined Chemical and Genetic Approach for the Generation of Induced Pluripotent Stem Cells
-
DOI 10.1016/j.stem.2008.05.011, PII S1934590908002257
-
Shi Y, Do JT, Desponts C, Hahm HS, Scholer HR, Ding S. 2008. A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell 2:525-28 (Pubitemid 351729222)
-
(2008)
Cell Stem Cell
, vol.2
, Issue.6
, pp. 525-528
-
-
Shi, Y.1
Tae Do, J.2
Desponts, C.3
Hahm, H.S.4
Scholer, H.R.5
Ding, S.6
-
22
-
-
73049086022
-
Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2
-
Li W, Zhou H, Abujarour R, Zhu S, Young Joo J, et al. 2009. Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. Stem Cells 27:2992-3000
-
(2009)
Stem Cells
, vol.27
, pp. 2992-3000
-
-
Li, W.1
Zhou, H.2
Abujarour, R.3
Zhu, S.4
Young Joo, J.5
-
23
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
DOI 10.1038/nature07056, PII NATURE07056
-
Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, et al. 2008. Dissecting direct reprogramming through integrative genomic analysis. Nature 454:49-55 (Pubitemid 351931978)
-
(2008)
Nature
, vol.454
, Issue.7200
, pp. 49-55
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, X.3
Ku, M.4
Wernig, M.5
Schorderet, P.6
Bernstein, B.E.7
Jaenisch, R.8
Lander, E.S.9
Meissner, A.10
-
24
-
-
54949115497
-
Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds
-
Shi Y, Desponts C, Do JT, Hahm HS, Scholer HR, Ding S. 2008. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell 3:568-74
-
(2008)
Cell Stem Cell
, vol.3
, pp. 568-574
-
-
Shi, Y.1
Desponts, C.2
Do, J.T.3
Hahm, H.S.4
Scholer, H.R.5
Ding, S.6
-
25
-
-
46949085597
-
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
-
DOI 10.1038/nbt1418, PII NBT1418
-
Huangfu D, Maehr R, Guo W, Eijkelenboom A, Snitow M, et al. 2008. Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat. Biotechnol. 26:795-97 (Pubitemid 351961456)
-
(2008)
Nature Biotechnology
, vol.26
, Issue.7
, pp. 795-797
-
-
Huangfu, D.1
Maehr, R.2
Guo, W.3
Eijkelenboom, A.4
Snitow, M.5
Chen, A.E.6
Melton, D.A.7
-
26
-
-
77950965653
-
Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes
-
Mali P, Chou BK, Yen J, Ye Z, Zou J, et al. 2010. Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells 28:713-20
-
(2010)
Stem Cells
, vol.28
, pp. 713-720
-
-
Mali, P.1
Chou, B.K.2
Yen, J.3
Ye, Z.4
Zou, J.5
-
27
-
-
66049135249
-
Generation of induced pluripotent stem cells using recombinant proteins
-
Zhou H, Wu S, Young Joo J, Zhu S, Han DW, et al. 2009. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4:381-84
-
(2009)
Cell Stem Cell
, vol.4
, pp. 381-384
-
-
Zhou, H.1
Wu, S.2
Young Joo, J.3
Zhu, S.4
Han, D.W.5
-
28
-
-
66049143859
-
Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
-
KimD,Kim CH,Moon JI, Chung YG, ChangMY, et al. 2009. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4:472-76
-
(2009)
Cell Stem Cell
, vol.4
, pp. 472-476
-
-
Kim, D.1
Kim, C.H.2
Moon, J.I.3
Chung, Y.G.4
Chang, M.Y.5
-
29
-
-
68949164755
-
Chd1 regulates open chromatin and pluripotency of embryonic stem cells
-
Gaspar-Maia A, Alajem A, Polesso F, SridharanR,Mason MJ, et al. 2009. Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature 460:863-68
-
(2009)
Nature
, vol.460
, pp. 863-868
-
-
Gaspar-Maia, A.1
Alajem, A.2
Polesso, F.3
Sridharan, R.4
Mason, M.J.5
-
30
-
-
77953727663
-
Chromatin-remodeling components of the BAF complex facilitate reprogramming
-
Singhal N, Graumann J,Wu G, Arauzo-Bravo MJ, Han DW, et al. 2010. Chromatin-remodeling components of the BAF complex facilitate reprogramming. Cell 141:943-55
-
(2010)
Cell
, vol.141
, pp. 943-955
-
-
Singhal, N.1
Graumann Jwu, G.2
Arauzo-Bravo, M.J.3
Han, D.W.4
-
31
-
-
78650752402
-
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
-
Polo JM, Liu S, Figueroa ME, Kulalert W, Eminli S, et al. 2010. Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat. Biotechnol. 28:848-55
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 848-855
-
-
Polo, J.M.1
Liu, S.2
Figueroa, M.E.3
Kulalert, W.4
Eminli, S.5
-
32
-
-
77955449906
-
Epigenetic memory in induced pluripotent stem cells
-
Kim K, Doi A, Wen B,Ng K, Zhao R, et al. 2010. Epigenetic memory in induced pluripotent stem cells. Nature 467:285-90
-
(2010)
Nature
, vol.467
, pp. 285-290
-
-
Kim, K.1
Doi, A.2
Wen Bng, K.3
Zhao, R.4
-
33
-
-
77953532417
-
Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells
-
Liu L, Luo GZ, YangW, Zhao X, Zheng Q, et al. 2010. Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. J. Biol. Chem. 285:19483-90
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 19483-19490
-
-
Liu, L.1
Luo, G.Z.2
Yang, W.3
Zhao, X.4
Zheng, Q.5
-
34
-
-
77952425747
-
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
-
Stadtfeld M, Apostolou E, Akutsu H, Fukuda A, Follett P, et al. 2010. Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature 465:175-81
-
(2010)
Nature
, vol.465
, pp. 175-181
-
-
Stadtfeld, M.1
Apostolou, E.2
Akutsu, H.3
Fukuda, A.4
Follett, P.5
-
35
-
-
70350732790
-
A chemical platform for improved induction of human iPSCs
-
LinT, Ambasudhan R, Yuan X, Li W, Hilcove S, et al. 2009. A chemical platform for improved induction of human iPSCs. Nat. Methods 6:805-8
-
(2009)
Nat. Methods
, vol.6
, pp. 805-8
-
-
Lin, T.1
Ambasudhan, R.2
Yuan, X.3
Li, W.4
Hilcove, S.5
-
36
-
-
77952360137
-
Revealing a core signaling regulatorymechanism for pluripotent stem cell survival and self-renewal by small molecules
-
Xu Y, ZhuX,Hahm HS, WeiW,Hao E, et al. 2010. Revealing a core signaling regulatorymechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc.Natl. Acad. Sci. USA 107:8129-34
-
(2010)
Proc.Natl. Acad. Sci. USA
, vol.107
, pp. 8129-81234
-
-
Xu, Y.1
Zhu, X.2
Hahm, H.S.3
Wei, W.4
Hao, E.5
-
37
-
-
77955801632
-
E-cadherin-mediated cell-cell contact is critical for induced pluripotent stem cell generation
-
Chen T, Yuan D, Wei B, Jiang J, Kang J, et al. 2010. E-cadherin-mediated cell-cell contact is critical for induced pluripotent stem cell generation. Stem Cells 28:1315-25
-
(2010)
Stem Cells
, vol.28
, pp. 1315-13125
-
-
Chen, T.1
Yuan, D.2
Wei, B.3
Jiang, J.4
Kang, J.5
-
38
-
-
77956320116
-
Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming
-
Samavarchi-Tehrani P, Golipour A, David L, Sung HK, Beyer TA, et al. 2010. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell 7:64-77
-
(2010)
Cell Stem Cell
, vol.7
, pp. 64-77
-
-
Samavarchi-Tehrani, P.1
Golipour, A.2
David, L.3
Sung, H.K.4
Beyer, T.A.5
-
39
-
-
77957551870
-
A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts
-
Li R, Liang J, Ni S, Zhou T, Qing X, et al. 2010. A mesenchymal-to- epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts. Cell Stem Cell 7:51-63
-
(2010)
Cell Stem Cell
, vol.7
, pp. 51-63
-
-
Li, R.1
Liang, J.2
Ni, S.3
Zhou, T.4
Qing, X.5
-
40
-
-
54949136146
-
Two supporting factors greatly improve the efficiency of human iPSC generation
-
Zhao Y, Yin X, Qin H, Zhu F, Liu H, et al. 2008. Two supporting factors greatly improve the efficiency of human iPSC generation. Cell Stem Cell 3:475-79
-
(2008)
Cell Stem Cell
, vol.3
, pp. 475-479
-
-
Zhao, Y.1
Yin, X.2
Qin, H.3
Zhu, F.4
Liu, H.5
-
41
-
-
71449109765
-
Direct cell reprogramming is a stochastic process amenable to acceleration
-
Hanna J, Saha K, Pando B, van Zon J, Lengner CJ, et al. 2009. Direct cell reprogramming is a stochastic process amenable to acceleration. Nature 462:595-601
-
(2009)
Nature
, vol.462
, pp. 595-601
-
-
Hanna, J.1
Saha, K.2
Pando, B.3
Van Zon, J.4
Lengner, C.J.5
-
42
-
-
69349100179
-
Suppression of induced pluripotent stem cell generation by the p53-p21 pathway
-
Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, et al. 2009. Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 460:1132-35
-
(2009)
Nature
, vol.460
, pp. 1132-11335
-
-
Hong, H.1
Takahashi, K.2
Ichisaka, T.3
Aoi, T.4
Kanagawa, O.5
-
43
-
-
69349098273
-
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
-
Utikal J, Polo JM, Stadtfeld M, Maherali N, Kulalert W, et al. 2009. Immortalization eliminates a roadblock during cellular reprogramming into iPS cells. Nature 460:1145-48
-
(2009)
Nature
, vol.460
, pp. 1145-11448
-
-
Utikal, J.1
Polo, J.M.2
Stadtfeld, M.3
Maherali, N.4
Kulalert, W.5
-
44
-
-
69349094006
-
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
-
Marion RM, Strati K, Li H, Murga M, Blanco R, et al. 2009. A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature 460:1149-53
-
(2009)
Nature
, vol.460
, pp. 1149-11453
-
-
Marion, R.M.1
Strati, K.2
Li, H.3
Murga, M.4
Blanco, R.5
-
45
-
-
58249085824
-
Role of themurine reprogramming factors in the induction of pluripotency
-
Sridharan R, Tchieu J,Mason MJ, Yachechko R, Kuoy E, et al. 2009. Role of themurine reprogramming factors in the induction of pluripotency. Cell 136:364-77
-
(2009)
Cell
, vol.136
, pp. 364-377
-
-
Sridharan, R.1
Tchieu Jmason, M.J.2
Yachechko, R.3
Kuoy, E.4
-
46
-
-
69349100455
-
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
-
Kawamura T, Suzuki J, Wang YV, Menendez S, Morera LB, et al. 2009. Linking the p53 tumour suppressor pathway to somatic cell reprogramming. Nature 460:1140-44
-
(2009)
Nature
, vol.460
, pp. 1140-11444
-
-
Kawamura, T.1
Suzuki, J.2
Wang, Y.V.3
Menendez, S.4
Morera, L.B.5
-
47
-
-
73049112178
-
Vitamin C enhances the generation of mouse and human induced pluripotent stem cells
-
Esteban MA, Wang T, Qin B, Yang J, Qin D, et al. 2010. Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. Cell Stem Cell 6:71-79
-
(2010)
Cell Stem Cell
, vol.6
, pp. 71-79
-
-
Esteban, M.A.1
Wang, T.2
Qin, B.3
Yang, J.4
Qin, D.5
-
48
-
-
77952545479
-
Metabolic oxidation regulates embryonic stem cell differentiation
-
Yanes O, Clark J, Wong DM, Patti GJ, Sanchez-Ruiz A, et al. 2010. Metabolic oxidation regulates embryonic stem cell differentiation. Nat. Chem. Biol. 6:411-17
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 411-417
-
-
Yanes, O.1
Clark, J.2
Wong, D.M.3
Patti, G.J.4
Sanchez-Ruiz, A.5
-
49
-
-
78649647814
-
Reprogramming of human primary somatic cells by OCT4 and chemical compounds
-
Zhu S, LiW, Zhou H,Wei W, Ambasudhan R, et al. 2010. Reprogramming of human primary somatic cells by OCT4 and chemical compounds. Cell Stem Cell 7:651-55
-
(2010)
Cell Stem Cell
, vol.7
, pp. 651-655
-
-
Zhu, S.1
Li, W.2
Zhou, H.3
Wei, W.4
Ambasudhan, R.5
-
50
-
-
69249210977
-
Hypoxia enhances the generation of induced pluripotent stem cells
-
Yoshida Y, Takahashi K, Okita K, Ichisaka T, Yamanaka S. 2009. Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell 5:237-41
-
(2009)
Cell Stem Cell
, vol.5
, pp. 237-241
-
-
Yoshida, Y.1
Takahashi, K.2
Okita, K.3
Ichisaka, T.4
Yamanaka, S.5
-
51
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB. 2009. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324:1029-33
-
(2009)
Science
, vol.324
, pp. 1029-10233
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
52
-
-
77956902055
-
Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules
-
Zhou H, Li W, Zhu S, Young Joo J, Do JT, et al. 2010. Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules. J. Biol. Chem. 285:29676-80
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 29676-29680
-
-
Zhou, H.1
Li, W.2
Zhu, S.3
Young Joo, J.4
Do, J.T.5
-
53
-
-
58049192815
-
Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors
-
Li W, WeiW, Zhu S, Zhu J, Shi Y, et al. 2009. Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. Cell Stem Cell 4:16-19
-
(2009)
Cell Stem Cell
, vol.4
, pp. 16-19
-
-
Li, W.1
Wei, W.2
Zhu, S.3
Zhu, J.4
Shi, Y.5
-
54
-
-
77956235887
-
A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells
-
Buecker C, Chen HH, Polo JM, Daheron L, Bu L, et al. 2010. A murine ESC-like state facilitates transgenesis and homologous recombination in human pluripotent stem cells. Cell Stem Cell 6:535-46
-
(2010)
Cell Stem Cell
, vol.6
, pp. 535-546
-
-
Buecker, C.1
Chen, H.H.2
Polo, J.M.3
Daheron, L.4
Bu, L.5
-
55
-
-
77952699848
-
Humanembryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs
-
Hanna J, ChengAW,Saha K, Kim J,Lengner CJ, et al. 2010.Humanembryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs. Proc. Natl. Acad. Sci. USA 107:9222-27
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 9222-92227
-
-
Hanna, J.1
Cheng, A.W.2
Saha, K.3
Kim, J.4
Lengner, C.J.5
-
56
-
-
0025114455
-
MyoD converts primary dermal fibroblasts, chondroblasts, smooth muscle, and retinal pigmented epithelial cells into striated mononucleated myoblasts and multinucleated myotubes
-
Choi J, Costa ML, Mermelstein CS, Chagas C, Holtzer S, Holtzer H. 1990. MyoD converts primary dermal fibroblasts, chondroblasts, smooth muscle, and retinal pigmented epithelial cells into striated mononucleated myoblasts and multinucleated myotubes. Proc. Natl. Acad. Sci. USA 87:7988-92
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 7988-79892
-
-
Choi, J.1
Costa, M.L.2
Mermelstein, C.S.3
Chagas, C.4
Holtzer, S.5
Holtzer, H.6
-
57
-
-
2542455620
-
Stepwise reprogramming of B cells into macrophages
-
DOI 10.1016/S0092-8674(04)00419-2, PII S0092867404004192
-
XieH, YeM, Feng R,Graf T. 2004. Stepwise reprogramming of B cells into macrophages. Cell 117:663-76 (Pubitemid 38692531)
-
(2004)
Cell
, vol.117
, Issue.5
, pp. 663-676
-
-
Xie, H.1
Ye, M.2
Feng, R.3
Graf, T.4
-
58
-
-
16244411316
-
Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals
-
DOI 10.1038/nm1193
-
Izumikawa M, Minoda R, Kawamoto K, Abrashkin KA, Swiderski DL, et al. 2005. Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals. Nat. Med. 11:271-76 (Pubitemid 40460554)
-
(2005)
Nature Medicine
, vol.11
, Issue.3
, pp. 271-276
-
-
Izumikawa, M.1
Minoda, R.2
Kawamoto, K.3
Abrashkin, K.A.4
Swiderski, D.L.5
Dolan, D.F.6
Brough, D.E.7
Raphael, Y.8
-
59
-
-
77957069984
-
Efficient reprogramming of adult neural stem cells to monocytes by ectopic expression of a single gene
-
Forsberg M, Carlen M, Meletis K, Yeung MS, Barnabe-Heider F, et al. 2010. Efficient reprogramming of adult neural stem cells to monocytes by ectopic expression of a single gene. Proc. Natl. Acad. Sci. USA 107:14657-61
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 14657-14661
-
-
Forsberg, M.1
Carlen, M.2
Meletis, K.3
Yeung, M.S.4
Barnabe-Heider, F.5
-
60
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
-
Zhou Q, Brown J, Kanarek A, Rajagopal J,Melton DA. 2008. In vivo reprogramming of adult pancreatic exocrine cells to β-cells. Nature 455:627-32
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
-
61
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Sudhof TC,Wernig M. 2010. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463:1035-41
-
(2010)
Nature
, vol.463
, pp. 1035-10341
-
-
Vierbuchen, T.1
Ostermeier, A.2
Pang, Z.P.3
Kokubu, Y.4
Sudhof Tcwernig, M.5
-
62
-
-
77955321344
-
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
-
Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, et al. 2010. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 142:375-86
-
(2010)
Cell
, vol.142
, pp. 375-386
-
-
Ieda, M.1
Fu, J.D.2
Delgado-Olguin, P.3
Vedantham, V.4
Hayashi, Y.5
-
63
-
-
39349106325
-
Differentiation of Embryonic Stem Cells to Clinically Relevant Populations: Lessons from Embryonic Development
-
DOI 10.1016/j.cell.2008.02.008, PII S009286740800216X
-
Murry CE, Keller G. 2008. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 132:661-80 (Pubitemid 351260059)
-
(2008)
Cell
, vol.132
, Issue.4
, pp. 661-680
-
-
Murry, C.E.1
Keller, G.2
-
64
-
-
62149125434
-
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
-
Chambers SM, Fasano CA, Papapetrou EP, Tomishima M, Sadelain M, Studer L. 2009. Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat. Biotechnol. 27:275-80
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 275-280
-
-
Chambers, S.M.1
Fasano, C.A.2
Papapetrou, E.P.3
Tomishima, M.4
Sadelain, M.5
Studer, L.6
-
65
-
-
70349327681
-
Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells
-
Idelson M, Alper R, Obolensky A, Ben-Shushan E, Hemo I, et al. 2009. Directed differentiation of human embryonic stem cells into functional retinal pigment epithelium cells. Cell Stem Cell 5:396-408
-
(2009)
Cell Stem Cell
, vol.5
, pp. 396-408
-
-
Idelson, M.1
Alper, R.2
Obolensky, A.3
Ben-Shushan, E.4
Hemo, I.5
-
66
-
-
77949892562
-
Efficient derivation of functional floor plate tissue from human embryonic stem cells
-
Fasano CA, Chambers SM, Lee G, Tomishima MJ, Studer L. 2010. Efficient derivation of functional floor plate tissue from human embryonic stem cells. Cell Stem Cell 6:336-47
-
(2010)
Cell Stem Cell
, vol.6
, pp. 336-347
-
-
Fasano, C.A.1
Chambers, S.M.2
Lee, G.3
Tomishima, M.J.4
Studer, L.5
-
67
-
-
77950995392
-
Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence
-
Feng Q, Lu SJ, Klimanskaya I, Gomes I, Kim D, et al. 2010. Hemangioblastic derivatives from human induced pluripotent stem cells exhibit limited expansion and early senescence. Stem Cells 28:704-12
-
(2010)
Stem Cells
, vol.28
, pp. 704-712
-
-
Feng, Q.1
Lu, S.J.2
Klimanskaya, I.3
Gomes, I.4
Kim, D.5
-
68
-
-
76349087336
-
Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFβ inhibition is Id1 dependent
-
James D, Nam HS, Seandel M, Nolan D, Janovitz T, et al. 2010. Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFβ inhibition is Id1 dependent. Nat. Biotechnol. 28:161-66
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 161-166
-
-
James, D.1
Nam, H.S.2
Seandel, M.3
Nolan, D.4
Janovitz, T.5
-
69
-
-
41849151748
-
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
-
DOI 10.1038/nbt1393, PII NBT1393
-
Kroon E, Martinson LA, Kadoya K, Bang AG, Kelly OG, et al. 2008. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat. Biotechnol. 26:443-52 (Pubitemid 351501814)
-
(2008)
Nature Biotechnology
, vol.26
, Issue.4
, pp. 443-452
-
-
Kroon, E.1
Martinson, L.A.2
Kadoya, K.3
Bang, A.G.4
Kelly, O.G.5
Eliazer, S.6
Young, H.7
Richardson, M.8
Smart, N.G.9
Cunningham, J.10
Agulnick, A.D.11
D'Amour, K.A.12
Carpenter, M.K.13
Baetge, E.E.14
-
70
-
-
70349437501
-
Generation of pluripotent stem cells from patients with type 1 diabetes
-
Maehr R, Chen S, Snitow M, Ludwig T, Yagasaki L, et al. 2009. Generation of pluripotent stem cells from patients with type 1 diabetes. Proc. Natl. Acad. Sci. USA 106:15768-73
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 15768-15773
-
-
Maehr, R.1
Chen, S.2
Snitow, M.3
Ludwig, T.4
Yagasaki, L.5
-
71
-
-
40449141341
-
Marked differences in differentiation propensity among human embryonic stem cell lines
-
DOI 10.1038/nbt1383, PII NBT1383
-
Osafune K, Caron L, Borowiak M, Martinez RJ, Fitz-Gerald CS, et al. 2008. Marked differences in differentiation propensity among human embryonic stem cell lines. Nat. Biotechnol. 26:313-15 (Pubitemid 351355125)
-
(2008)
Nature Biotechnology
, vol.26
, Issue.3
, pp. 313-315
-
-
Osafune, K.1
Caron, L.2
Borowiak, M.3
Martinez, R.J.4
Fitz-Gerald, C.S.5
Sato, Y.6
Cowan, C.A.7
Chien, K.R.8
Melton, D.A.9
-
72
-
-
77749279749
-
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
-
Hu BY, Weick JP, Yu J, Ma LX, Zhang XQ, et al. 2010. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc. Natl. Acad. Sci. USA 107:4335-40
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 4335-43340
-
-
Hu, B.Y.1
Weick, J.P.2
Yu, J.3
Ma, L.X.4
Zhang, X.Q.5
-
73
-
-
33845996144
-
Activin A efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed
-
DOI 10.1634/stemcells.2006-0219
-
McLean AB, D'Amour KA, Jones KL, Krishnamoorthy M, Kulik MJ, et al. 2007. Activin A efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed. Stem Cells 25:29-38 (Pubitemid 46052972)
-
(2007)
Stem Cells
, vol.25
, Issue.1
, pp. 29-38
-
-
McLean, A.B.1
D'Amour, K.A.2
Jones, K.L.3
Krishnamoorthy, M.4
Kulik, M.J.5
Reynolds, D.M.6
Sheppard, A.M.7
Liu, H.8
Xu, Y.9
Baetge, E.E.10
Dalton, S.11
-
74
-
-
65349086683
-
A small molecule primes embryonic stem cells for differentiation
-
Zhu S, Wurdak H, Wang J, Lyssiotis CA, Peters EC, et al. 2009. A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell 4:416-26
-
(2009)
Cell Stem Cell
, vol.4
, pp. 416-426
-
-
Zhu, S.1
Wurdak, H.2
Wang, J.3
Lyssiotis, C.A.4
Peters, E.C.5
-
75
-
-
0030584081
-
Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity
-
DOI 10.1016/S0092-8674(00)81386-0
-
Ericson J, Morton S, Kawakami A, RoelinkH, Jessell TM. 1996. Two critical periods of SonicHedgehog signaling required for the specification of motor neuron identity. Cell 87:661-73 (Pubitemid 26386940)
-
(1996)
Cell
, vol.87
, Issue.4
, pp. 661-673
-
-
Ericson, J.1
Morton, S.2
Kawakami, A.3
Roelink, H.4
Jessell, T.M.5
-
76
-
-
62949210744
-
Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells
-
Borowiak M, Maehr R, Chen S, Chen AE, Tang W, et al. 2009. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell 4:348-58
-
(2009)
Cell Stem Cell
, vol.4
, pp. 348-358
-
-
Borowiak, M.1
Maehr, R.2
Chen, S.3
Chen, A.E.4
Tang, W.5
-
77
-
-
62649138086
-
A small molecule that directs differentiation of human ESCs into the pancreatic lineage
-
Chen S, Borowiak M, Fox JL, Maehr R, Osafune K, et al. 2009. A small molecule that directs differentiation of human ESCs into the pancreatic lineage. Nat. Chem. Biol. 5:258-65
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 258-265
-
-
Chen, S.1
Borowiak, M.2
Fox, J.L.3
Maehr, R.4
Osafune, K.5
-
78
-
-
77956519710
-
Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells
-
Boitano AE, Wang J, Romeo R, Bouchez LC, Parker AE, et al. 2010. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells. Science 329:1345-48
-
(2010)
Science
, vol.329
, pp. 1345-13448
-
-
Boitano, A.E.1
Wang, J.2
Romeo, R.3
Bouchez, L.C.4
Parker, A.E.5
-
79
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
DOI 10.1038/nm979
-
Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. 2004. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat. Med. 10:55-63 (Pubitemid 38524699)
-
(2004)
Nature Medicine
, vol.10
, Issue.1
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
80
-
-
55949121679
-
Wnt-mediated self-renewal of neural stem/progenitor cells
-
Kalani MY, Cheshier SH, Cord BJ, Bababeygy SR, Vogel H, et al. 2008. Wnt-mediated self-renewal of neural stem/progenitor cells. Proc. Natl. Acad. Sci. USA 105:16970-75
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 16970-16975
-
-
Kalani, M.Y.1
Cheshier, S.H.2
Cord, B.J.3
Bababeygy, S.R.4
Vogel, H.5
-
81
-
-
77956628008
-
Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture
-
Zeng YA, Nusse R. 2010. Wnt proteins are self-renewal factors for mammary stem cells and promote their long-term expansion in culture. Cell Stem Cell 6:568-77
-
(2010)
Cell Stem Cell
, vol.6
, pp. 568-577
-
-
Zeng, Y.A.1
Nusse, R.2
-
82
-
-
0037737728
-
A role for Wnt signalling in self-renewal of haematopoietic stem cells
-
DOI 10.1038/nature01593
-
Reya T, DuncanAW,AillesL,Domen J, SchererDC, et al. 2003.Arole forWntsignalling in self-renewal of haematopoietic stem cells. Nature 423:409-14 (Pubitemid 36626987)
-
(2003)
Nature
, vol.423
, Issue.6938
, pp. 409-414
-
-
Reya, T.1
Duncan, A.W.2
Ailles, L.3
Domen, J.4
Scherer, D.C.5
Willert, K.6
Hintz, L.7
Nusse, R.8
Weissman, I.L.9
-
83
-
-
34548437672
-
AMD3100 and CD26 modulate mobilization, engraftment, and survival of hematopoietic stem and progenitor cells mediated by the SDF-1/CXCL12-CXCR4 axis
-
DOI 10.1196/annals.1392.013, Hematopoietic Stem Cells VI
-
Broxmeyer HE, Hangoc G, Cooper S, Campbell T, Ito S, Mantel C. 2007. AMD3100 and CD26 modulate mobilization, engraftment, and survival of hematopoietic stem and progenitor cells mediated by the SDF-1/CXCL12-CXCR4 axis. Ann. N. Y. Acad. Sci. 1106:1-19 (Pubitemid 47443049)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1106
, pp. 1-19
-
-
Broxmeyer, H.E.1
Hangoc, G.2
Cooper, S.3
Campbell, T.4
Ito, S.5
Mantel, C.6
-
84
-
-
39149137857
-
Stem Cell Trafficking in Tissue Development, Growth, and Disease
-
DOI 10.1016/j.cell.2008.01.041, PII S0092867408001979
-
Laird DJ, von Andrian UH,Wagers AJ. 2008. Stem cell trafficking in tissue development, growth, and disease. Cell 132:612-30 (Pubitemid 351253693)
-
(2008)
Cell
, vol.132
, Issue.4
, pp. 612-630
-
-
Laird, D.J.1
Von Andrian, U.H.2
Wagers, A.J.3
-
85
-
-
64249173226
-
The AMD3100 story: The path to the discovery of a stem cell mobilizer (Mozobil)
-
De Clercq E. 2009. The AMD3100 story: the path to the discovery of a stem cell mobilizer (Mozobil). Biochem. Pharmacol. 77:1655-64
-
(2009)
Biochem. Pharmacol.
, vol.77
, pp. 1655-16564
-
-
De Clercq, E.1
-
86
-
-
67049134758
-
Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation
-
Hoggatt J, Singh P, Sampath J, Pelus LM. 2009. Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation. Blood 113:5444-55
-
(2009)
Blood
, vol.113
, pp. 5444-54455
-
-
Hoggatt, J.1
Singh, P.2
Sampath, J.3
Pelus, L.M.4
-
87
-
-
34347366261
-
Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice
-
Campbell TB, Hangoc G, Liu Y, Pollok K, Broxmeyer HE. 2007. Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice. Stem Cells Dev. 16:347-54
-
(2007)
Stem Cells Dev.
, vol.16
, pp. 347-354
-
-
Campbell, T.B.1
Hangoc, G.2
Liu, Y.3
Pollok, K.4
Broxmeyer, H.E.5
-
88
-
-
34347325114
-
+ peripheral blood cells
-
DOI 10.1089/scd.2007.9997
-
Kawai T, Choi U, Liu PC,Whiting-Theobald NL, Linton GF, Malech HL. 2007. Diprotin A infusion into nonobese diabetic/severe combined immunodeficiency mice markedly enhances engraftment of human mobilized CD34+ peripheral blood cells. Stem Cells Dev. 16:361-70 (Pubitemid 47016221)
-
(2007)
Stem Cells and Development
, vol.16
, Issue.3
, pp. 361-370
-
-
Kawai, T.1
Choi, U.2
Liu, P.-C.3
Whiting-Theobald, N.L.4
Linton, G.F.5
Malech, H.L.6
-
89
-
-
34347334543
-
null immunodeficient mice
-
DOI 10.1089/scd.2007.9996
-
Christopherson KW II, Paganessi LA, Napier S, Porecha NK. 2007. CD26 inhibition on CD34+ or lineage? human umbilical cord blood donor hematopoietic stem cells/hematopoietic progenitor cells improves long-term engraftment into NOD/SCID/Beta2null immunodeficient mice. Stem Cells Dev. 16:355-60 (Pubitemid 47016220)
-
(2007)
Stem Cells and Development
, vol.16
, Issue.3
, pp. 355-360
-
-
Christopherson II, K.W.1
Paganessi, L.A.2
Napier, S.3
Porecha, N.K.4
-
90
-
-
55849115999
-
Induced pluripotent stem cells generated without viral integration
-
Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K. 2008. Induced pluripotent stem cells generated without viral integration. Science 322:945-49
-
(2008)
Science
, vol.322
, pp. 945-949
-
-
Stadtfeld, M.1
Nagaya, M.2
Utikal, J.3
Weir, G.4
Hochedlinger, K.5
-
91
-
-
72849137462
-
Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells
-
ZhouW,Freed CR. 2009. Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells. Stem Cells 27:2667-74
-
(2009)
Stem Cells
, vol.27
, pp. 2667-26674
-
-
Zhou, W.1
Freed, C.R.2
-
92
-
-
55849117368
-
Generation of mouse induced pluripotent stem cells without viral vectors
-
Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S. 2008. Generation of mouse induced pluripotent stem cells without viral vectors. Science 322:949-53
-
(2008)
Science
, vol.322
, pp. 949-953
-
-
Okita, K.1
Nakagawa, M.2
Hyenjong, H.3
Ichisaka, T.4
Yamanaka, S.5
-
93
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
Soldner F, Hockemeyer D, Beard C, Gao Q, Bell GW, et al. 2009. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136:964-77
-
(2009)
Cell
, vol.136
, pp. 964-977
-
-
Soldner, F.1
Hockemeyer, D.2
Beard, C.3
Gao, Q.4
Bell, G.W.5
-
94
-
-
65649116572
-
Human induced pluripotent stem cells free of vector and transgene sequences
-
Yu J, Hu K, Smuga-Otto K, Tian S, Stewart R, et al. 2009. Human induced pluripotent stem cells free of vector and transgene sequences. Science 324:797-801
-
(2009)
Science
, vol.324
, pp. 797-801
-
-
Yu, J.1
Hu, K.2
Smuga-Otto, K.3
Tian, S.4
Stewart, R.5
-
95
-
-
77649275936
-
A nonviral minicircle vector for deriving human iPS cells
-
Jia F, Wilson KD, Sun N, Gupta DM, Huang M, et al. 2010. A nonviral minicircle vector for deriving human iPS cells. Nat. Methods 7:197-99
-
(2010)
Nat. Methods
, vol.7
, pp. 197-199
-
-
Jia, F.1
Wilson, K.D.2
Sun, N.3
Gupta, D.M.4
Huang, M.5
-
96
-
-
64749111225
-
Virus-free induction of pluripotency and subsequent excision of reprogramming factors
-
Kaji K, NorrbyK, Paca A, MileikovskyM,Mohseni P, WoltjenK. 2009. Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 458:771-75
-
(2009)
Nature
, vol.458
, pp. 771-775
-
-
Kaji, K.1
Norrby, K.2
Paca, A.3
Mileikovsky, M.4
Mohseni, P.5
Woltjen, K.6
-
97
-
-
64749083939
-
PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
-
Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, et al. 2009. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458:766-70
-
(2009)
Nature
, vol.458
, pp. 766-770
-
-
Woltjen, K.1
Michael, I.P.2
Mohseni, P.3
Desai, R.4
Mileikovsky, M.5
-
98
-
-
77949793550
-
Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors
-
Yakubov E, RechaviG,Rozenblatt S,Givol D. 2010. Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors. Biochem. Biophys. Res. Commun. 394:189-93
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.394
, pp. 189-193
-
-
Yakubov, E.1
Rechavi, G.2
Rozenblatt, S.3
Givol, D.4
-
99
-
-
77958536106
-
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
-
Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, et al. 2010. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7:618-30
-
(2010)
Cell Stem Cell
, vol.7
, pp. 618-630
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
Loh, Y.H.4
Li, H.5
-
100
-
-
55749104227
-
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
-
Huangfu D, Osafune K, Maehr R, Guo W, Eijkelenboom A, et al. 2008. Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat. Biotechnol. 26:1269-75
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 1269-12675
-
-
Huangfu, D.1
Osafune, K.2
Maehr, R.3
Guo, W.4
Eijkelenboom, A.5
-
101
-
-
70350536767
-
A small-molecule inhibitor of TGF-β signaling replaces Sox2 in reprogramming by inducing Nanog
-
Ichida JK, Blanchard J, Lam K, Son EY, Chung JE, et al. 2009. A small-molecule inhibitor of TGF-β signaling replaces Sox2 in reprogramming by inducing Nanog. Cell Stem Cell 5:491-503
-
(2009)
Cell Stem Cell
, vol.5
, pp. 491-503
-
-
Ichida, J.K.1
Blanchard, J.2
Lam, K.3
Son, E.Y.4
Chung, J.E.5
-
102
-
-
67049158201
-
Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4
-
Lyssiotis CA, Foreman RK, Staerk J, Garcia M, Mathur D, et al. 2009. Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proc. Natl. Acad. Sci. USA 106:8912-17
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 8912-89117
-
-
Lyssiotis, C.A.1
Foreman, R.K.2
Staerk, J.3
Garcia, M.4
Mathur, D.5
-
103
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
Park IH, Zhao R,West JA, Yabuuchi A, Huo H, et al. 2008. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451:141-46
-
(2008)
Nature
, vol.451
, pp. 141-146
-
-
Park, I.H.1
Zhao Rwest, J.A.2
Yabuuchi, A.3
Huo, H.4
-
104
-
-
78650915547
-
Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules
-
Li Y, Zhang Q, Yin X, Yang W, Du Y, et al. 2011. Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Res. 21:196-204
-
(2011)
Cell Res.
, vol.21
, pp. 196-204
-
-
Li, Y.1
Zhang, Q.2
Yin, X.3
Yang, W.4
Du, Y.5
-
105
-
-
78650881444
-
BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone
-
Chen J, Liu J, Yang J, Chen Y, Chen J, et al. 2011. BMPs functionally replace Klf4 and support efficient reprogramming of mouse fibroblasts by Oct4 alone. Cell Res. 21:205-12
-
(2011)
Cell Res.
, vol.21
, pp. 205-212
-
-
Chen, J.1
Liu, J.2
Yang, J.3
Chen, Y.4
Chen, J.5
-
106
-
-
79953001876
-
Combined chemical treatment enables Oct4-induced reprogramming from mouse embryonic fibroblasts
-
Yuan X, Wan H, Zhao X, Zhu S, Zhou Q, Ding S. 2011. Combined chemical treatment enables Oct4-induced reprogramming from mouse embryonic fibroblasts. Stem Cells 29:549-53
-
(2011)
Stem Cells
, vol.29
, pp. 549-553
-
-
Yuan, X.1
Wan, H.2
Zhao, X.3
Zhu, S.4
Zhou, Q.5
Ding, S.6
|