Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules

Journal of Biological Chemistry

Volumn 285, Issue 39, 2010, Pages 29676-29680

  Zhou, Hongyan ^a   Li, Wenlin ^a   Zhu, Saiyong ^a   Joo, Jin Young ^b   Do, Jeong Tae ^b,c   Xiong, Wen ^a   Kim, Jeong Beom ^b   Zhang, Kang ^d   Schöler, Hans R ^b   Ding, Sheng ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b MAX PLANCK INSTITUTE FOR MOLECULAR BIOMEDICINE   (Germany)

^c CHA University   (South Korea)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE EXPRESSION;

HISTONE DEMETHYLASE LSD1; IN-VITRO; INNER CELL MASS; MORPHOLOGICAL CHANGES; MURINE EMBRYONIC STEM CELLS; PLURIPOTENCY; PLURIPOTENT; POST-IMPLANTATION; SMALL MOLECULE INHIBITOR; SMALL MOLECULES;

STEM CELLS;

BETA TUBULIN; BETAIII TUBULIN; CD31 ANTIGEN; FIBROBLAST GROWTH FACTOR 4; FIBROBLAST GROWTH FACTOR 5; FIBROBLAST GROWTH FACTOR RECEPTOR; GENE PRODUCT; HISTONE DEMETHYLASE LSD1; KRUPPEL LIKE FACTOR 4; MICROTUBULE ASSOCIATED PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; N DEMETHYLASE; NUCLEAR RECEPTOR DAX 1; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN BRACHYURY; PROTEIN ESRRB; PROTEIN FBXO15; PROTEIN GSK3; PROTEIN LSD1; PROTEIN MEK; PROTEIN STRA8; STAGE SPECIFIC EMBRYO ANTIGEN 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR REX1; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR STELLA; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; UNCLASSIFIED DRUG; AOF2 PROTEIN, MOUSE; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; TGF-BETA TYPE I RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ANIMAL CELL; ARTICLE; CELL AGGREGATION; CELL DIFFERENTIATION; CELL GROWTH; CELL RENEWAL; CELL STRUCTURE; CELL SURVIVAL; CHIMERA; CONTROLLED STUDY; DNA METHYLATION; EMBRYONIC STEM CELL; ENZYME INHIBITION; EPIBLAST STEM CELL; EPIGENETICS; GENE EXPRESSION; MORULA; MOUSE; NONHUMAN; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL DEDIFFERENTIATION; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENETIC EPIGENESIS; GERM LAYER; METABOLISM;

MURINAE;

ANIMALS; CELL DEDIFFERENTIATION; CELL LINE; CHIMERISM; EMBRYONIC STEM CELLS; ENZYME INHIBITORS; EPIGENESIS, GENETIC; GERM LAYERS; MAP KINASE KINASE KINASES; MICE; OXIDOREDUCTASES, N-DEMETHYLATING; PLURIPOTENT STEM CELLS; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA;

EID: 77956902055     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.C110.150599     Document Type: Article

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