Glycogen synthase kinase 3β inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons

Neuro-Oncology

Volumn 13, Issue 5, 2011, Pages 459-470

  Yang, Eddy S ^a,b   Nowsheen, Somaira ^a,b   Wang, Tong ^a   Thotala, Dinesh K ^c   Xia, Fen ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cranial irradiation; DNA damage and repair; GSK3; Neuroprotection; Nonhomologous end joining

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; 2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; DOUBLE STRANDED DNA; GLYCOGEN SYNTHASE KINASE 3BETA; HISTONE H2AX;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BRAIN NERVE CELL; BRAIN RADIATION; COMET ASSAY; DNA REPAIR; DNA STRAND BREAKAGE; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC REGULATION; HIPPOCAMPUS; MOUSE; NERVE CELL CULTURE; NEUROPROTECTION; NONHUMAN; RADIATION INJURY;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; COMET ASSAY; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; GLIOMA; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; HUMANS; MICE; NEURONS; RNA, SMALL INTERFERING;

EID: 79960027267     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nor016     Document Type: Article

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