메뉴 건너뛰기




Volumn 75, Issue 3, 2008, Pages 773-780

Protective effect of N-acetylcysteine against radiation induced DNA damage and hepatic toxicity in rats

Author keywords

Radiation; Antioxidant; N Acetylcysteine; Nitric oxide and DNA damage

Indexed keywords

ACETYLCYSTEINE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; NITRATE; NITRITE; SUPEROXIDE DISMUTASE;

EID: 37849004297     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.09.018     Document Type: Article
Times cited : (116)

References (51)
  • 1
    • 26644437215 scopus 로고    scopus 로고
    • Identification of mammalian proteins cross-linked to DNA by ionizing radiation
    • Barker S., Weinfeld M., Zheng J., Li, and Murray D. Identification of mammalian proteins cross-linked to DNA by ionizing radiation. J Biol Chem 280 40 (2005) 33826-33838
    • (2005) J Biol Chem , vol.280 , Issue.40 , pp. 33826-33838
    • Barker, S.1    Weinfeld, M.2    Zheng, J.3    Li4    Murray, D.5
  • 2
    • 0032786631 scopus 로고    scopus 로고
    • Reactive oxygen species: the unavoidable environmental insults?
    • Gracy R.W., Talent J.M., Kong Y., and Conrad C.C. Reactive oxygen species: the unavoidable environmental insults?. Mutat Res 428 (1999) 17-22
    • (1999) Mutat Res , vol.428 , pp. 17-22
    • Gracy, R.W.1    Talent, J.M.2    Kong, Y.3    Conrad, C.C.4
  • 3
    • 0034073027 scopus 로고    scopus 로고
    • Effect of melatonin against oxidative stress in ultraviolet-B exposed rat lens
    • Bardak Y., Ozerturk Y., Ozguner F., Durmus M., and Delibas N. Effect of melatonin against oxidative stress in ultraviolet-B exposed rat lens. Curr Eye Res 20 (2000) 225-230
    • (2000) Curr Eye Res , vol.20 , pp. 225-230
    • Bardak, Y.1    Ozerturk, Y.2    Ozguner, F.3    Durmus, M.4    Delibas, N.5
  • 4
    • 0034371311 scopus 로고    scopus 로고
    • Fluorescence and ESR studies on membrane oxidative damage by γ-radiation
    • Pandey B.N., and Mishra K.P. Fluorescence and ESR studies on membrane oxidative damage by γ-radiation. Appl Magn Reson 18 (2000) 483-492
    • (2000) Appl Magn Reson , vol.18 , pp. 483-492
    • Pandey, B.N.1    Mishra, K.P.2
  • 5
    • 0041402784 scopus 로고    scopus 로고
    • Radioprotective effects of 2-iminothiazolidine derivatives against lethal doses of gamma radiation in mice
    • Hosseinimehr S.J., Shafiee A., Mozdarani H., and Akhlagpour S. Radioprotective effects of 2-iminothiazolidine derivatives against lethal doses of gamma radiation in mice. J Radiat Res 42 (2001) 401-408
    • (2001) J Radiat Res , vol.42 , pp. 401-408
    • Hosseinimehr, S.J.1    Shafiee, A.2    Mozdarani, H.3    Akhlagpour, S.4
  • 7
    • 0003605672 scopus 로고    scopus 로고
    • Hall E.J. (Ed), Lippincott Williams & Wilkins, Philadelphia, Pa
    • Hall E.J. In: Hall E.J. (Ed). Radiobiology for the radiologist (2000), Lippincott Williams & Wilkins, Philadelphia, Pa 17-31
    • (2000) Radiobiology for the radiologist , pp. 17-31
    • Hall, E.J.1
  • 8
    • 0347986908 scopus 로고    scopus 로고
    • Five cysteine-containing compounds have antioxidative activity in Balb/cA mice
    • Hsu C.C., Huang C.N., Hung Y.C., and Yin M.C. Five cysteine-containing compounds have antioxidative activity in Balb/cA mice. J Nutr 134 (2004) 149-152
    • (2004) J Nutr , vol.134 , pp. 149-152
    • Hsu, C.C.1    Huang, C.N.2    Hung, Y.C.3    Yin, M.C.4
  • 9
    • 11144234507 scopus 로고    scopus 로고
    • Biologically important thiols in various vegetables and fruits
    • Demirkol O., Adams C., and Ercal N. Biologically important thiols in various vegetables and fruits. J Agric Food Chem 52 26 (2004) 8151-8154
    • (2004) J Agric Food Chem , vol.52 , Issue.26 , pp. 8151-8154
    • Demirkol, O.1    Adams, C.2    Ercal, N.3
  • 10
    • 0036136731 scopus 로고    scopus 로고
    • Angioprevention: angiogenesis is a common and key target for cancer chemopreventive agents
    • Tosetti F., Ferrari N., De Flora S., and Albini A. Angioprevention: angiogenesis is a common and key target for cancer chemopreventive agents. FASEB J 16 1 (2002) 2-14
    • (2002) FASEB J , vol.16 , Issue.1 , pp. 2-14
    • Tosetti, F.1    Ferrari, N.2    De Flora, S.3    Albini, A.4
  • 11
    • 0037447993 scopus 로고    scopus 로고
    • Glutathione depletion increases nitric oxide-induced oxidative stress in primary rat hepatocyte cultures: involvement of low-molecular-weight iron
    • Sinbandhit-Tricot S., Cillard J., Chevanne M., Morel I., Cillard P., and Sergent O. Glutathione depletion increases nitric oxide-induced oxidative stress in primary rat hepatocyte cultures: involvement of low-molecular-weight iron. Free Radic Biol Med 34 10 (2003) 1283-1294
    • (2003) Free Radic Biol Med , vol.34 , Issue.10 , pp. 1283-1294
    • Sinbandhit-Tricot, S.1    Cillard, J.2    Chevanne, M.3    Morel, I.4    Cillard, P.5    Sergent, O.6
  • 12
    • 0036958539 scopus 로고    scopus 로고
    • Lipid peroxidation-mediated cytotoxicity and DNA damage in U937 cells
    • Park J.E., Yang J.H., Yoon S.J., Lee J.H., Yang E.S., and Park J.W. Lipid peroxidation-mediated cytotoxicity and DNA damage in U937 cells. Biochimie 84 (2002) 1199-1205
    • (2002) Biochimie , vol.84 , pp. 1199-1205
    • Park, J.E.1    Yang, J.H.2    Yoon, S.J.3    Lee, J.H.4    Yang, E.S.5    Park, J.W.6
  • 13
    • 3442902484 scopus 로고    scopus 로고
    • Effect of N-acetylcysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice
    • Reliene R., Fischer E., and Schiestl R.H. Effect of N-acetylcysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice. Cancer Res 64 (2004) 5148-5153
    • (2004) Cancer Res , vol.64 , pp. 5148-5153
    • Reliene, R.1    Fischer, E.2    Schiestl, R.H.3
  • 14
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H., Ohishi N., and Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95 2 (1979) 351-358
    • (1979) Anal Biochem , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 15
    • 0017067418 scopus 로고
    • Glutathione peroxidase activity in selenium-deficient rat liver
    • Lawrence R.A., and Burk R.F. Glutathione peroxidase activity in selenium-deficient rat liver. Biochem Biophys Res Commun 71 (1976) 952-958
    • (1976) Biochem Biophys Res Commun , vol.71 , pp. 952-958
    • Lawrence, R.A.1    Burk, R.F.2
  • 16
    • 0018409235 scopus 로고
    • A simplified assay method of superoxide dismutase activity for clinical use
    • Minami M., and Yoshikawa H. A simplified assay method of superoxide dismutase activity for clinical use. Clin Chim Acta 92 (1979) 337-342
    • (1979) Clin Chim Acta , vol.92 , pp. 337-342
    • Minami, M.1    Yoshikawa, H.2
  • 17
    • 0016151122 scopus 로고
    • Bromobenze induced liver necrosis: protective role of glutathione and evidence for 3,4-bromobenzenoxide as the hepatotoxic intermediate
    • Jollow D., Mitchell L., Zampaglione N., and Gillete J. Bromobenze induced liver necrosis: protective role of glutathione and evidence for 3,4-bromobenzenoxide as the hepatotoxic intermediate. Pharmacology 11 (1974) 151-169
    • (1974) Pharmacology , vol.11 , pp. 151-169
    • Jollow, D.1    Mitchell, L.2    Zampaglione, N.3    Gillete, J.4
  • 18
    • 0035709008 scopus 로고    scopus 로고
    • A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite
    • Miranda K.M., Espey M.G., and Wink D.A. A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite. Nitric Oxide Biol Chem 5 (2001) 62-71
    • (2001) Nitric Oxide Biol Chem , vol.5 , pp. 62-71
    • Miranda, K.M.1    Espey, M.G.2    Wink, D.A.3
  • 19
    • 0030595324 scopus 로고    scopus 로고
    • Induction and its spread of apoptosis in rat spinal cord mechanical trauma
    • Katoh K., Ikata T., Katoh S., Hamada Y., Nakauchi K., Sano T., et al. Induction and its spread of apoptosis in rat spinal cord mechanical trauma. Neurosci Lett 216 (1996) 9-12
    • (1996) Neurosci Lett , vol.216 , pp. 9-12
    • Katoh, K.1    Ikata, T.2    Katoh, S.3    Hamada, Y.4    Nakauchi, K.5    Sano, T.6
  • 20
    • 0035200385 scopus 로고    scopus 로고
    • Role of ginsenoside-Rd in cisplatin-induced renal injury: special reference to DNA fragmentation
    • Yokozawa T., and Dong E. Role of ginsenoside-Rd in cisplatin-induced renal injury: special reference to DNA fragmentation. Nephron 89 (2001) 433-438
    • (2001) Nephron , vol.89 , pp. 433-438
    • Yokozawa, T.1    Dong, E.2
  • 23
    • 23644441924 scopus 로고    scopus 로고
    • Enhancement of radiation-induced oxidative stress and cytotoxicity in tumor cells by ellagic acid
    • Bhosle S.M., Huilgol N.G., and Mishra K.P. Enhancement of radiation-induced oxidative stress and cytotoxicity in tumor cells by ellagic acid. Clin Chim Acta 359 (2005) 89-100
    • (2005) Clin Chim Acta , vol.359 , pp. 89-100
    • Bhosle, S.M.1    Huilgol, N.G.2    Mishra, K.P.3
  • 24
    • 15944362568 scopus 로고    scopus 로고
    • Radioprotective effect of sesamol on γ-radiation induced DNA damage, lipid peroxidation and antioxidants levels in cultured human lymphocytes
    • Rajendra Prasad N., Menon V.P., Vasudev V., and Pugalendi K.V. Radioprotective effect of sesamol on γ-radiation induced DNA damage, lipid peroxidation and antioxidants levels in cultured human lymphocytes. Toxicology 209 (2005) 225-235
    • (2005) Toxicology , vol.209 , pp. 225-235
    • Rajendra Prasad, N.1    Menon, V.P.2    Vasudev, V.3    Pugalendi, K.V.4
  • 25
    • 10844260075 scopus 로고    scopus 로고
    • Spinacia oleracea L. protects against gamma radiations: a study on glutathione and lipid peroxidation in mouse liver
    • Bhatia A.L., and Jain M. Spinacia oleracea L. protects against gamma radiations: a study on glutathione and lipid peroxidation in mouse liver. Phytomedicine 11 7-8 (2004) 607-615
    • (2004) Phytomedicine , vol.11 , Issue.7-8 , pp. 607-615
    • Bhatia, A.L.1    Jain, M.2
  • 26
    • 1542651158 scopus 로고    scopus 로고
    • Melatonin protects rat liver against irradiation-induced oxidative injury
    • Koc M., Taysi S., Buyukokuroglu M.E., and Bakan N. Melatonin protects rat liver against irradiation-induced oxidative injury. J Radiat Res 44 (2003) 211-215
    • (2003) J Radiat Res , vol.44 , pp. 211-215
    • Koc, M.1    Taysi, S.2    Buyukokuroglu, M.E.3    Bakan, N.4
  • 27
    • 11244258947 scopus 로고    scopus 로고
    • Radioprotective effect of abana, a polyherbal drug following total body irradiation
    • Baliga M.S., Jagetia G.C., Venkatesh P., Reddy R., and Ulloor J.N. Radioprotective effect of abana, a polyherbal drug following total body irradiation. Br J Radiol 77 924 (2004) 1027-1035
    • (2004) Br J Radiol , vol.77 , Issue.924 , pp. 1027-1035
    • Baliga, M.S.1    Jagetia, G.C.2    Venkatesh, P.3    Reddy, R.4    Ulloor, J.N.5
  • 28
    • 0033932014 scopus 로고    scopus 로고
    • Activation of the nitric oxide synthase 2 pathway in the response of bone marrow stromal cells to high doses of ionizing radiation
    • Gorbunov N.V., Pogue-Geile K.L., Epperly M.W., Bigbee W.L., Draviam R., Day B.W., et al. Activation of the nitric oxide synthase 2 pathway in the response of bone marrow stromal cells to high doses of ionizing radiation. Radiat Res 154 (2000) 73-86
    • (2000) Radiat Res , vol.154 , pp. 73-86
    • Gorbunov, N.V.1    Pogue-Geile, K.L.2    Epperly, M.W.3    Bigbee, W.L.4    Draviam, R.5    Day, B.W.6
  • 29
    • 0031057566 scopus 로고    scopus 로고
    • Enhancement of NO production from resident peritoneal macrophages by in vitro gamma-irradiation and its relationship to reactive oxygen intermediates
    • Ibuki Y., and Goto R. Enhancement of NO production from resident peritoneal macrophages by in vitro gamma-irradiation and its relationship to reactive oxygen intermediates. Free Radic Biol Med 22 6 (1997) 1029-1035
    • (1997) Free Radic Biol Med , vol.22 , Issue.6 , pp. 1029-1035
    • Ibuki, Y.1    Goto, R.2
  • 30
    • 32044460146 scopus 로고    scopus 로고
    • In vivo nitric oxide production and iNOS expression in X-ray irradiated mouse skin
    • Chi C., Ozawa T., and Anzai K. In vivo nitric oxide production and iNOS expression in X-ray irradiated mouse skin. Biol Pharm Bull 29 2 (2006) 348-353
    • (2006) Biol Pharm Bull , vol.29 , Issue.2 , pp. 348-353
    • Chi, C.1    Ozawa, T.2    Anzai, K.3
  • 31
    • 24144473718 scopus 로고    scopus 로고
    • Inhibition of radiation induced nitration by curcumin and nicotinamide in mouse macrophages
    • Narang H., and Krishna M. Inhibition of radiation induced nitration by curcumin and nicotinamide in mouse macrophages. Mol Cell Biochem 276 12 (2005) 7-13
    • (2005) Mol Cell Biochem , vol.276 , Issue.12 , pp. 7-13
    • Narang, H.1    Krishna, M.2
  • 32
    • 21744447869 scopus 로고    scopus 로고
    • Ionizing radiation-induced macrophage activation: augmentation of nitric oxide production and its significance
    • Ibuki Y., and Goto R. Ionizing radiation-induced macrophage activation: augmentation of nitric oxide production and its significance. Cell Mol Biol 50 (2004) 617-626
    • (2004) Cell Mol Biol , vol.50 , pp. 617-626
    • Ibuki, Y.1    Goto, R.2
  • 33
    • 0036769736 scopus 로고    scopus 로고
    • Radioprotective effects of 2-imino-3{(chromone-2-yl) carbonyl} thiazolidines against gamma irradiation in mice
    • Hosseinimehr S.J., Shafiee A., Mozdarani H., Akhlagpour S., and Froughizadeh M. Radioprotective effects of 2-imino-3{(chromone-2-yl) carbonyl} thiazolidines against gamma irradiation in mice. J Radiat Res 43 (2002) 293-300
    • (2002) J Radiat Res , vol.43 , pp. 293-300
    • Hosseinimehr, S.J.1    Shafiee, A.2    Mozdarani, H.3    Akhlagpour, S.4    Froughizadeh, M.5
  • 34
    • 1542441602 scopus 로고    scopus 로고
    • Radioprotective effects of citrus extract against gamma irradiation in mouse bone marrow cells
    • Hosseinimehr S.J., Tavakoli H., Pourheidari G.R., Sobhani A., and Shafiee A. Radioprotective effects of citrus extract against gamma irradiation in mouse bone marrow cells. J Radiat Res 44 (2003) 237-241
    • (2003) J Radiat Res , vol.44 , pp. 237-241
    • Hosseinimehr, S.J.1    Tavakoli, H.2    Pourheidari, G.R.3    Sobhani, A.4    Shafiee, A.5
  • 35
    • 0031027060 scopus 로고    scopus 로고
    • Paraquat-induced formation of leukotriene B4 in rat lungs: modulation by N-acetylcysteine
    • Hoffer E.L., Shenker Y., Baum Y., and Tabak A. Paraquat-induced formation of leukotriene B4 in rat lungs: modulation by N-acetylcysteine. Free Radic Biol Med 22 (1997) 567-572
    • (1997) Free Radic Biol Med , vol.22 , pp. 567-572
    • Hoffer, E.L.1    Shenker, Y.2    Baum, Y.3    Tabak, A.4
  • 36
    • 0035037015 scopus 로고    scopus 로고
    • Redox paradox: effect of N-acetylcysteine and serum on oxidation reduction-sensitive mitogen-activated protein kinase signaling pathways
    • Chan E.D., Riches D.W.H., and White C.W. Redox paradox: effect of N-acetylcysteine and serum on oxidation reduction-sensitive mitogen-activated protein kinase signaling pathways. Am J Respir Cell Mol Biol 24 5 (2001) 627-632
    • (2001) Am J Respir Cell Mol Biol , vol.24 , Issue.5 , pp. 627-632
    • Chan, E.D.1    Riches, D.W.H.2    White, C.W.3
  • 37
    • 33745006163 scopus 로고    scopus 로고
    • Nitric oxide inhibits HIF-1alpha protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron
    • Kozhukhar A.V., Yasinska I.M., and Sumbayev V.V. Nitric oxide inhibits HIF-1alpha protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron. Biochimie 88 5 (2006) 411-418
    • (2006) Biochimie , vol.88 , Issue.5 , pp. 411-418
    • Kozhukhar, A.V.1    Yasinska, I.M.2    Sumbayev, V.V.3
  • 38
    • 33646519687 scopus 로고    scopus 로고
    • Cytotoxicity induced by grape seed proanthocyanidins: role of nitric oxide
    • Shao Z.H., Hsu C.W., Chang W.T., Waypa G.B., Li J., Li D., et al. Cytotoxicity induced by grape seed proanthocyanidins: role of nitric oxide. Cell Biol Toxicol 22 3 (2006) 149-158
    • (2006) Cell Biol Toxicol , vol.22 , Issue.3 , pp. 149-158
    • Shao, Z.H.1    Hsu, C.W.2    Chang, W.T.3    Waypa, G.B.4    Li, J.5    Li, D.6
  • 39
    • 20444377322 scopus 로고    scopus 로고
    • Attenuation of bleomycin-induced lung fibrosis by oral sulfhydryl containing antioxidants in rats: erdosteine and N-acetylcysteine
    • Yildirim Z., Kotuk M., Iraz M., Kuku I., Ulu R., Armutcu F., et al. Attenuation of bleomycin-induced lung fibrosis by oral sulfhydryl containing antioxidants in rats: erdosteine and N-acetylcysteine. Pulm Pharmacol Ther 18 5 (2005) 367-373
    • (2005) Pulm Pharmacol Ther , vol.18 , Issue.5 , pp. 367-373
    • Yildirim, Z.1    Kotuk, M.2    Iraz, M.3    Kuku, I.4    Ulu, R.5    Armutcu, F.6
  • 40
    • 20144375857 scopus 로고    scopus 로고
    • Neuroprotective effect of N-acetyl cysteine on hypoxia-induced oxidative stress in primary hippocampal culture
    • Jayalakshmi K., Sairam M., Singh S.B., Sharma S.K., Ilavazhagan G., and Banerjee P.K. Neuroprotective effect of N-acetyl cysteine on hypoxia-induced oxidative stress in primary hippocampal culture. Brain Res 1046 Jun 7 (1-2) (2005) 97-104
    • (2005) Brain Res , vol.1046 , Issue.Jun 7 1-2 , pp. 97-104
    • Jayalakshmi, K.1    Sairam, M.2    Singh, S.B.3    Sharma, S.K.4    Ilavazhagan, G.5    Banerjee, P.K.6
  • 41
    • 33645079384 scopus 로고    scopus 로고
    • N-Acetylcysteine abrogates acute lung injury induced by endotoxin
    • Kao S.J., Wang D., Lin H.I., and Chen H.I. N-Acetylcysteine abrogates acute lung injury induced by endotoxin. Clin Ep Pharmacol Physiol 33 1-2 (2006) 33-40
    • (2006) Clin Ep Pharmacol Physiol , vol.33 , Issue.1-2 , pp. 33-40
    • Kao, S.J.1    Wang, D.2    Lin, H.I.3    Chen, H.I.4
  • 42
    • 1642339441 scopus 로고    scopus 로고
    • N-Acetyl-cysteine modulates inducible nitric oxide synthase gene expression in human hepatocytes
    • Majano P.L., Medina J., Zubia I., Sunyer L., Lara-Pezzi E., Maldonado-Rodriguez A., et al. N-Acetyl-cysteine modulates inducible nitric oxide synthase gene expression in human hepatocytes. J Hepatol 40 4 (2004) 632-637
    • (2004) J Hepatol , vol.40 , Issue.4 , pp. 632-637
    • Majano, P.L.1    Medina, J.2    Zubia, I.3    Sunyer, L.4    Lara-Pezzi, E.5    Maldonado-Rodriguez, A.6
  • 43
    • 34047255787 scopus 로고    scopus 로고
    • Protective effect of ferulic acid on nicotine-induced DNA damage and cellular changes in cultured rat peripheral blood lymphocytes: a comparison with N-acetylcysteine
    • Sudheer A.R., Muthukumaran S., Kalpana C., Srinivasan M., and Menon V.P. Protective effect of ferulic acid on nicotine-induced DNA damage and cellular changes in cultured rat peripheral blood lymphocytes: a comparison with N-acetylcysteine. Toxicol Vitro 21 4 (2007) 576-585
    • (2007) Toxicol Vitro , vol.21 , Issue.4 , pp. 576-585
    • Sudheer, A.R.1    Muthukumaran, S.2    Kalpana, C.3    Srinivasan, M.4    Menon, V.P.5
  • 44
    • 0003264585 scopus 로고    scopus 로고
    • N-Acetylcysteine and endothelial cell injury by sulfur mustard
    • Atkins K.B., Lodhi I.J., Hurley L.L., and Hinshaw D.B. N-Acetylcysteine and endothelial cell injury by sulfur mustard. J Appl Toxicol Suppl 1 (2000) S125-S128
    • (2000) J Appl Toxicol , Issue.SUPPL. 1
    • Atkins, K.B.1    Lodhi, I.J.2    Hurley, L.L.3    Hinshaw, D.B.4
  • 45
    • 17644417124 scopus 로고    scopus 로고
    • Role of ERK in hydrogen peroxide-induced cell death of human glioma cells
    • Lee W.C., Choi C.H., Cha S.H., Oh H.L., and Kim Y.K. Role of ERK in hydrogen peroxide-induced cell death of human glioma cells. Neurochem Res 30 (2005) 263-270
    • (2005) Neurochem Res , vol.30 , pp. 263-270
    • Lee, W.C.1    Choi, C.H.2    Cha, S.H.3    Oh, H.L.4    Kim, Y.K.5
  • 46
    • 0036197307 scopus 로고    scopus 로고
    • Acetaminophen hepatotoxicity and mechanisms of its protection by N-acetylcysteine: a study of Hep3B cells
    • Manov I., Hirsh M., and Iancu T.C. Acetaminophen hepatotoxicity and mechanisms of its protection by N-acetylcysteine: a study of Hep3B cells. Exp Toxicol Pathol 53 (2002) 489-500
    • (2002) Exp Toxicol Pathol , vol.53 , pp. 489-500
    • Manov, I.1    Hirsh, M.2    Iancu, T.C.3
  • 47
    • 0036170022 scopus 로고    scopus 로고
    • Protective effect of N-acetylcysteine against gamma ray induced damages in rats biochemical evaluations
    • Sridharan S., and Shyamaladevi C.S. Protective effect of N-acetylcysteine against gamma ray induced damages in rats biochemical evaluations. Indian J Exp Biol 40 2 (2002) 181-186
    • (2002) Indian J Exp Biol , vol.40 , Issue.2 , pp. 181-186
    • Sridharan, S.1    Shyamaladevi, C.S.2
  • 48
    • 0031742632 scopus 로고    scopus 로고
    • Radiation-sensitive tyrosine phosphorylation of cellular proteins: sensitive to changes in GSH content induced by pretreatment with N-acetyl-l-cysteine or l-buthionine-S,R-sulfoximine
    • Tuttle S., Horan A.M., Koch C.J., Held K., Manevich Y., and Biaglow J. Radiation-sensitive tyrosine phosphorylation of cellular proteins: sensitive to changes in GSH content induced by pretreatment with N-acetyl-l-cysteine or l-buthionine-S,R-sulfoximine. Int J Radiat Oncol Biol Phys 42 4 (1998) 833-838
    • (1998) Int J Radiat Oncol Biol Phys , vol.42 , Issue.4 , pp. 833-838
    • Tuttle, S.1    Horan, A.M.2    Koch, C.J.3    Held, K.4    Manevich, Y.5    Biaglow, J.6
  • 49
    • 0033192561 scopus 로고    scopus 로고
    • Effect of N-acetylcysteine on UVB-induced apoptosis and DNA repair in human and mouse keratinocytes
    • Bush J.A., Ho V.C., Mitchell D.L., Tron V.A., and Li G. Effect of N-acetylcysteine on UVB-induced apoptosis and DNA repair in human and mouse keratinocytes. Photochem Photobiol 70 3 (1999) 329-333
    • (1999) Photochem Photobiol , vol.70 , Issue.3 , pp. 329-333
    • Bush, J.A.1    Ho, V.C.2    Mitchell, D.L.3    Tron, V.A.4    Li, G.5
  • 50
    • 0032428720 scopus 로고    scopus 로고
    • Protective effects of antioxidants against UVA-induced DNA damage in human skin fibroblasts in culture
    • Emonet-Piccardi N., Richard M.J., Ravanat J.L., Signorini N., Cadet J., and Beani J.C. Protective effects of antioxidants against UVA-induced DNA damage in human skin fibroblasts in culture. Free Radic Res 29 4 (1998) 307-313
    • (1998) Free Radic Res , vol.29 , Issue.4 , pp. 307-313
    • Emonet-Piccardi, N.1    Richard, M.J.2    Ravanat, J.L.3    Signorini, N.4    Cadet, J.5    Beani, J.C.6
  • 51
    • 0036496285 scopus 로고    scopus 로고
    • UV-B-induced formation of reactive oxygen species and oxidative damage of the cyanobacterium Anaaena sp.: protective effects of ascorbic acid and N-acetyl-l-cysteine
    • He Y.Y., and Hader D.P. UV-B-induced formation of reactive oxygen species and oxidative damage of the cyanobacterium Anaaena sp.: protective effects of ascorbic acid and N-acetyl-l-cysteine. J Photocem Photobiol B 66 2 (2002) 115-124
    • (2002) J Photocem Photobiol B , vol.66 , Issue.2 , pp. 115-124
    • He, Y.Y.1    Hader, D.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.