Increased levels of the Akt-specific phosphatase PH domain leucine-rich repeat protein phosphatase (PHLPP)-1 in obese participants are associated with insulin resistance

Diabetologia

Volumn 54, Issue 7, 2011, Pages 1879-1887

  Andreozzi, F ^a   Procopio, C ^a   Greco, A ^a   Mannino, G C ^a   Miele, C ^b   Raciti, G A ^b   Iadicicco, C ^b   Beguinot, F ^b   Pontiroli, A E ^c   Hribal, M L ^a   Folli, F ^d   Sesti, G ^a  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d University of Texas Health Science Center   (United States)

Author keywords

Adipose tissue; Akt; Insulin signalling; Obesity; PHLPP

Indexed keywords

AKT SPECIFIC PHOSPHATASE PH DOMAIN LEUCINE RICH REPEAT PROTEIN PHOSPHATASE 1; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3; INSULIN; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BODY MASS; CELL STRAIN HEPG2; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; GLYCOGEN SYNTHESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; MORBID OBESITY; MYOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SKELETAL MUSCLE; SUBCUTANEOUS FAT; UPREGULATION;

ADOLESCENT; ADULT; AGED; ANIMALS; BLOTTING, WESTERN; CELL LINE; FEMALE; HEP G2 CELLS; HUMANS; INSULIN RESISTANCE; MALE; MIDDLE AGED; NUCLEAR PROTEINS; OBESITY; PHOSPHOPROTEIN PHOSPHATASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; YOUNG ADULT;

EID: 79959686257     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2116-6     Document Type: Article

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