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Volumn 12, Issue 6, 2011, Pages

The mouse genetics toolkit: Revealing function and mechanism

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINASE;

EID: 79959572206     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2011-12-6-224     Document Type: Review
Times cited : (37)

References (120)
  • 1
    • 0037279626 scopus 로고    scopus 로고
    • One hundred years of mouse genetics: an intellectual history. I. The classical period (1902-1980).
    • 1462407, 12586691
    • Paigen K. One hundred years of mouse genetics: an intellectual history. I. The classical period (1902-1980). Genetics 2003, 163:1-7. 1462407, 12586691.
    • (2003) Genetics , vol.163 , pp. 1-7
    • Paigen, K.1
  • 2
    • 34548348147 scopus 로고    scopus 로고
    • On the subspecific origin of the laboratory mouse.
    • 10.1038/ng2087, 17660819
    • Yang H, Bell TA, Churchill GA, Pardo-Manuel de Villena F. On the subspecific origin of the laboratory mouse. Nat Genet 2007, 39:1100-1107. 10.1038/ng2087, 17660819.
    • (2007) Nat Genet , vol.39 , pp. 1100-1107
    • Yang, H.1    Bell, T.A.2    Churchill, G.A.3    Pardo-Manuel de Villena, F.4
  • 10
    • 84903467654 scopus 로고    scopus 로고
    • The Wellcome Trust Sanger Institute Mouse Portal.
    • The Wellcome Trust Sanger Institute Mouse Portal. , http://www.sanger.ac.uk/mouseportal/
  • 11
    • 0022369586 scopus 로고
    • Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia.
    • 10.1073/pnas.82.19.6619, 391261, 3863118
    • Hitotsumachi S, Carpenter DA, Russell WL. Dose-repetition increases the mutagenic effectiveness of N-ethyl-N-nitrosourea in mouse spermatogonia. Proc Natl Acad Sci USA 1985, 82:6619-6621. 10.1073/pnas.82.19.6619, 391261, 3863118.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 6619-6621
    • Hitotsumachi, S.1    Carpenter, D.A.2    Russell, W.L.3
  • 14
    • 34250736757 scopus 로고    scopus 로고
    • Precis on forward genetics in mice.
    • 10.1038/ni0707-659, 17579639
    • Beutler B, Du X, Xia Y. Precis on forward genetics in mice. Nat Immunol 2007, 8:659-664. 10.1038/ni0707-659, 17579639.
    • (2007) Nat Immunol , vol.8 , pp. 659-664
    • Beutler, B.1    Du, X.2    Xia, Y.3
  • 17
    • 77955350348 scopus 로고    scopus 로고
    • Current applications of transposons in mouse genetics.
    • Dupuy AJ. Current applications of transposons in mouse genetics. Methods Enzymol 2010, 477:53-70.
    • (2010) Methods Enzymol , vol.477 , pp. 53-70
    • Dupuy, A.J.1
  • 18
    • 0025992469 scopus 로고
    • Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.
    • 10.1101/gad.5.9.1513, 1653172
    • Friedrich G, Soriano P. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev 1991, 5:1513-1523. 10.1101/gad.5.9.1513, 1653172.
    • (1991) Genes Dev , vol.5 , pp. 1513-1523
    • Friedrich, G.1    Soriano, P.2
  • 20
    • 2642522640 scopus 로고
    • Genetic transformation of mouse embryos by microinjection of purified DNA.
    • 10.1073/pnas.77.12.7380, 350507, 6261253
    • Gordon JW, Scangos GA, Plotkin DJ, Barbosa JA, Ruddle FH. Genetic transformation of mouse embryos by microinjection of purified DNA. Proc Natl Acad Sci USA 1980, 77:7380-7384. 10.1073/pnas.77.12.7380, 350507, 6261253.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 7380-7384
    • Gordon, J.W.1    Scangos, G.A.2    Plotkin, D.J.3    Barbosa, J.A.4    Ruddle, F.H.5
  • 22
    • 77949768138 scopus 로고    scopus 로고
    • Long human CHGA flanking chromosome 14 sequence required for optimal BAC transgenic "rescue" of disease phenotypes in the mouse Chga knockout.
    • 10.1152/physiolgenomics.00086.2009, 2841496, 20009010
    • Vaingankar SM, Li Y, Corti A, Biswas N, Gayen J, O'Connor DT, Mahata SK. Long human CHGA flanking chromosome 14 sequence required for optimal BAC transgenic "rescue" of disease phenotypes in the mouse Chga knockout. Physiol Genomics 2010, 41:91-101. 10.1152/physiolgenomics.00086.2009, 2841496, 20009010.
    • (2010) Physiol Genomics , vol.41 , pp. 91-101
    • Vaingankar, S.M.1    Li, Y.2    Corti, A.3    Biswas, N.4    Gayen, J.5    O'Connor, D.T.6    Mahata, S.K.7
  • 23
    • 0023646810 scopus 로고
    • Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells.
    • Thomas KR, Capecchi MR. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 1987, 51:503-512.
    • (1987) Cell , vol.51 , pp. 503-512
    • Thomas, K.R.1    Capecchi, M.R.2
  • 24
    • 0033152654 scopus 로고    scopus 로고
    • A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice.
    • 10.1093/nar/27.11.2354, 148802, 10325425
    • Zheng B, Mills AA, Bradley A. A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice. Nucleic Acids Res 1999, 27:2354-2360. 10.1093/nar/27.11.2354, 148802, 10325425.
    • (1999) Nucleic Acids Res , vol.27 , pp. 2354-2360
    • Zheng, B.1    Mills, A.A.2    Bradley, A.3
  • 25
    • 65549088559 scopus 로고    scopus 로고
    • Chromosome engineering in ES cells.
    • 10.1007/978-1-59745-471-1_4, 19266329
    • van der Weyden L, Shaw-Smith C, Bradley A. Chromosome engineering in ES cells. Methods Mol Biol 2009, 530:49-77. 10.1007/978-1-59745-471-1_4, 19266329.
    • (2009) Methods Mol Biol , vol.530 , pp. 49-77
    • van der Weyden, L.1    Shaw-Smith, C.2    Bradley, A.3
  • 26
    • 34447503838 scopus 로고    scopus 로고
    • Transgenic RNA interference in mice.
    • Gao X, Zhang P. Transgenic RNA interference in mice. Physiology (Bethesda) 2007, 22:161-166.
    • (2007) Physiology (Bethesda) , vol.22 , pp. 161-166
    • Gao, X.1    Zhang, P.2
  • 28
    • 79952484127 scopus 로고    scopus 로고
    • Progress and prospects: oligonucleotide-directed gene modification in mouse embryonic stem cells: a route to therapeutic application.
    • 10.1038/gt.2010.161, 21160530
    • Aarts M, Te Riele H. Progress and prospects: oligonucleotide-directed gene modification in mouse embryonic stem cells: a route to therapeutic application. Gene Ther 2011, 18:213-219. 10.1038/gt.2010.161, 21160530.
    • (2011) Gene Ther , vol.18 , pp. 213-219
    • Aarts, M.1    Te Riele, H.2
  • 29
    • 77957005768 scopus 로고    scopus 로고
    • Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases.
    • 10.1073/pnas.1009424107, 2930558, 20686113
    • Meyer M, de Angelis MH, Wurst W, Kuhn R. Gene targeting by homologous recombination in mouse zygotes mediated by zinc-finger nucleases. Proc Natl Acad Sci USA 2010, 107:15022-15026. 10.1073/pnas.1009424107, 2930558, 20686113.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 15022-15026
    • Meyer, M.1    de Angelis, M.H.2    Wurst, W.3    Kuhn, R.4
  • 30
    • 57049096639 scopus 로고    scopus 로고
    • Contemporary approaches for modifying the mouse genome.
    • 10.1152/physiolgenomics.90242.2008, 2519963, 18559964
    • Adams DJ, van der Weyden L. Contemporary approaches for modifying the mouse genome. Physiol Genomics 2008, 34:225-238. 10.1152/physiolgenomics.90242.2008, 2519963, 18559964.
    • (2008) Physiol Genomics , vol.34 , pp. 225-238
    • Adams, D.J.1    van der Weyden, L.2
  • 34
    • 0035487293 scopus 로고    scopus 로고
    • Recombineering: a powerful new tool for mouse functional genomics.
    • Copeland NG, Jenkins NA, Court DL. Recombineering: a powerful new tool for mouse functional genomics. Nat Rev Genet 2001, 2:769-779.
    • (2001) Nat Rev Genet , vol.2 , pp. 769-779
    • Copeland, N.G.1    Jenkins, N.A.2    Court, D.L.3
  • 35
    • 70450200653 scopus 로고    scopus 로고
    • Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice.
    • 10.1242/dmm.003087, 19692579
    • Anastassiadis K, Fu J, Patsch C, Hu S, Weidlich S, Duerschke K, Buchholz F, Edenhofer F, Stewart AF. Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice. Dis Model Mech 2009, 2:508-515. 10.1242/dmm.003087, 19692579.
    • (2009) Dis Model Mech , vol.2 , pp. 508-515
    • Anastassiadis, K.1    Fu, J.2    Patsch, C.3    Hu, S.4    Weidlich, S.5    Duerschke, K.6    Buchholz, F.7    Edenhofer, F.8    Stewart, A.F.9
  • 36
    • 70349257594 scopus 로고    scopus 로고
    • Site-specific recombinases for manipulation of the mouse genome.
    • 10.1007/978-1-60327-019-9_16, 19504076
    • Birling MC, Gofflot F, Warot X. Site-specific recombinases for manipulation of the mouse genome. Methods Mol Biol 2009, 561:245-263. 10.1007/978-1-60327-019-9_16, 19504076.
    • (2009) Methods Mol Biol , vol.561 , pp. 245-263
    • Birling, M.C.1    Gofflot, F.2    Warot, X.3
  • 37
    • 0037657915 scopus 로고    scopus 로고
    • A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse.
    • 10.1038/nbt811, 12665802
    • Schnutgen F, Doerflinger N, Calleja C, Wendling O, Chambon P, Ghyselinck NB. A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse. Nat Biotechnol 2003, 21:562-565. 10.1038/nbt811, 12665802.
    • (2003) Nat Biotechnol , vol.21 , pp. 562-565
    • Schnutgen, F.1    Doerflinger, N.2    Calleja, C.3    Wendling, O.4    Chambon, P.5    Ghyselinck, N.B.6
  • 38
    • 0035490099 scopus 로고    scopus 로고
    • Engineering chromosomal rearrangements in mice.
    • Yu Y, Bradley A. Engineering chromosomal rearrangements in mice. Nat Rev Genet 2001, 2:780-790.
    • (2001) Nat Rev Genet , vol.2 , pp. 780-790
    • Yu, Y.1    Bradley, A.2
  • 40
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.
    • 10.1073/pnas.89.12.5547, 49329, 1319065
    • Gossen M, Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 1992, 89:5547-5551. 10.1073/pnas.89.12.5547, 49329, 1319065.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 41
    • 0035876445 scopus 로고    scopus 로고
    • The lac operator-repressor system is functional in the mouse.
    • 10.1101/gad.892001, 312721, 11410531
    • Cronin CA, Gluba W, Scrable H. The lac operator-repressor system is functional in the mouse. Genes Dev 2001, 15:1506-1517. 10.1101/gad.892001, 312721, 11410531.
    • (2001) Genes Dev , vol.15 , pp. 1506-1517
    • Cronin, C.A.1    Gluba, W.2    Scrable, H.3
  • 42
    • 0029767838 scopus 로고    scopus 로고
    • Ligand-activated site-specific recombination in mice.
    • 10.1073/pnas.93.20.10887, 38252, 8855277
    • Feil R, Brocard J, Mascrez B, LeMeur M, Metzger D, Chambon P. Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci USA 1996, 93:10887-10890. 10.1073/pnas.93.20.10887, 38252, 8855277.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 10887-10890
    • Feil, R.1    Brocard, J.2    Mascrez, B.3    LeMeur, M.4    Metzger, D.5    Chambon, P.6
  • 43
    • 77954675836 scopus 로고    scopus 로고
    • Genetic control of active neural circuits.
    • 2802553, 20057936
    • Reijmers L, Mayford M. Genetic control of active neural circuits. Front Mol Neurosci 2009, 2:27. 2802553, 20057936.
    • (2009) Front Mol Neurosci , vol.2 , pp. 27
    • Reijmers, L.1    Mayford, M.2
  • 44
    • 65549134763 scopus 로고    scopus 로고
    • Creation and use of a cre recombinase transgenic database.
    • 10.1007/978-1-59745-471-1_19, 19266338
    • Nagy A, Mar L, Watts G. Creation and use of a cre recombinase transgenic database. Methods Mol Biol 2009, 530:365-378. 10.1007/978-1-59745-471-1_19, 19266338.
    • (2009) Methods Mol Biol , vol.530 , pp. 365-378
    • Nagy, A.1    Mar, L.2    Watts, G.3
  • 45
    • 0030851192 scopus 로고    scopus 로고
    • Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function.
    • Wassarman KM, Lewandoski M, Campbell K, Joyner AL, Rubenstein JL, Martinez S, Martin GR. Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development 1997, 124:2923-2934.
    • (1997) Development , vol.124 , pp. 2923-2934
    • Wassarman, K.M.1    Lewandoski, M.2    Campbell, K.3    Joyner, A.L.4    Rubenstein, J.L.5    Martinez, S.6    Martin, G.R.7
  • 46
    • 42449098832 scopus 로고    scopus 로고
    • Variable expression of Cre recombinase transgenes precludes reliable prediction of tissue-specific gene disruption by tail-biopsy genotyping.
    • 10.1371/journal.pone.0001013, 1995755, 17925861
    • Schulz TJ, Glaubitz M, Kuhlow D, Thierbach R, Birringer M, Steinberg P, Pfeiffer AF, Ristow M. Variable expression of Cre recombinase transgenes precludes reliable prediction of tissue-specific gene disruption by tail-biopsy genotyping. PLoS One 2007, 2:e1013. 10.1371/journal.pone.0001013, 1995755, 17925861.
    • (2007) PLoS One , vol.2
    • Schulz, T.J.1    Glaubitz, M.2    Kuhlow, D.3    Thierbach, R.4    Birringer, M.5    Steinberg, P.6    Pfeiffer, A.F.7    Ristow, M.8
  • 47
    • 78951477016 scopus 로고    scopus 로고
    • When Cre-mediated recombination in mice does not result in protein loss.
    • 10.1534/genetics.110.121608, 20813881
    • Turlo KA, Gallaher SD, Vora R, Laski FA, Iruela-Arispe ML. When Cre-mediated recombination in mice does not result in protein loss. Genetics 2010, 186:959-967. 10.1534/genetics.110.121608, 20813881.
    • (2010) Genetics , vol.186 , pp. 959-967
    • Turlo, K.A.1    Gallaher, S.D.2    Vora, R.3    Laski, F.A.4    Iruela-Arispe, M.L.5
  • 48
    • 79952310557 scopus 로고    scopus 로고
    • Recombinase-mediated cassette exchange (RMCE): traditional concepts and current challenges.
    • 10.1016/j.jmb.2011.01.004, 21241707
    • Turan S, Galla M, Ernst E, Qiao J, Voelkel C, Schiedlmeier B, Zehe C, Bode J. Recombinase-mediated cassette exchange (RMCE): traditional concepts and current challenges. J Mol Biol 2011, 407:193-221. 10.1016/j.jmb.2011.01.004, 21241707.
    • (2011) J Mol Biol , vol.407 , pp. 193-221
    • Turan, S.1    Galla, M.2    Ernst, E.3    Qiao, J.4    Voelkel, C.5    Schiedlmeier, B.6    Zehe, C.7    Bode, J.8
  • 49
    • 36148961543 scopus 로고    scopus 로고
    • Road to precision: recombinase-based targeting technologies for genome engineering.
    • 10.1016/j.copbio.2007.07.013, 17904350
    • Wirth D, Gama-Norton L, Riemer P, Sandhu U, Schucht R, Hauser H. Road to precision: recombinase-based targeting technologies for genome engineering. Curr Opin Biotechnol 2007, 18:411-419. 10.1016/j.copbio.2007.07.013, 17904350.
    • (2007) Curr Opin Biotechnol , vol.18 , pp. 411-419
    • Wirth, D.1    Gama-Norton, L.2    Riemer, P.3    Sandhu, U.4    Schucht, R.5    Hauser, H.6
  • 50
    • 77954373875 scopus 로고    scopus 로고
    • Recombinase mediated cassette exchange into genomic targets using an adenovirus vector.
    • 10.1093/nar/gkq192, 2887974, 20371519
    • Sorrell DA, Robinson CJ, Smith JA, Kolb AF. Recombinase mediated cassette exchange into genomic targets using an adenovirus vector. Nucleic Acids Res 2010, 38:e123. 10.1093/nar/gkq192, 2887974, 20371519.
    • (2010) Nucleic Acids Res , vol.38
    • Sorrell, D.A.1    Robinson, C.J.2    Smith, J.A.3    Kolb, A.F.4
  • 51
    • 78049331001 scopus 로고    scopus 로고
    • Dual RMCE for efficient re-engineering of mouse mutant alleles.
    • 10.1038/nmeth.1521, 20953177
    • Osterwalder M, Galli A, Rosen B, Skarnes WC, Zeller R, Lopez-Rios J. Dual RMCE for efficient re-engineering of mouse mutant alleles. Nat Methods 2010, 7:893-895. 10.1038/nmeth.1521, 20953177.
    • (2010) Nat Methods , vol.7 , pp. 893-895
    • Osterwalder, M.1    Galli, A.2    Rosen, B.3    Skarnes, W.C.4    Zeller, R.5    Lopez-Rios, J.6
  • 52
    • 79954508872 scopus 로고    scopus 로고
    • Rapid derivation of genetically related mutants from embryonic cells harboring a recombinase-specific Trp53 platform.
    • 10.4161/cc.10.8.15303, 21445009
    • Wei QX, Odell AF, van der Hoeven F, Hollstein M. Rapid derivation of genetically related mutants from embryonic cells harboring a recombinase-specific Trp53 platform. Cell Cycle 2011, 10:1261-1270. 10.4161/cc.10.8.15303, 21445009.
    • (2011) Cell Cycle , vol.10 , pp. 1261-1270
    • Wei, Q.X.1    Odell, A.F.2    van der Hoeven, F.3    Hollstein, M.4
  • 55
    • 79952707077 scopus 로고    scopus 로고
    • Genetic screens using the piggyBac transposon.
    • 10.1016/j.ymeth.2010.12.022, 21185377
    • Chew SK, Rad R, Futreal PA, Bradley A, Liu P. Genetic screens using the piggyBac transposon. Methods 2011, 53:366-371. 10.1016/j.ymeth.2010.12.022, 21185377.
    • (2011) Methods , vol.53 , pp. 366-371
    • Chew, S.K.1    Rad, R.2    Futreal, P.A.3    Bradley, A.4    Liu, P.5
  • 58
    • 22444431606 scopus 로고    scopus 로고
    • Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system.
    • 10.1038/nature03691, 16015321
    • Dupuy AJ, Akagi K, Largaespada DA, Copeland NG, Jenkins NA. Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system. Nature 2005, 436:221-226. 10.1038/nature03691, 16015321.
    • (2005) Nature , vol.436 , pp. 221-226
    • Dupuy, A.J.1    Akagi, K.2    Largaespada, D.A.3    Copeland, N.G.4    Jenkins, N.A.5
  • 59
    • 22444444402 scopus 로고    scopus 로고
    • Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse.
    • 10.1038/nature03681, 16015333
    • Collier LS, Carlson CM, Ravimohan S, Dupuy AJ, Largaespada DA. Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse. Nature 2005, 436:272-276. 10.1038/nature03681, 16015333.
    • (2005) Nature , vol.436 , pp. 272-276
    • Collier, L.S.1    Carlson, C.M.2    Ravimohan, S.3    Dupuy, A.J.4    Largaespada, D.A.5
  • 64
    • 70449729803 scopus 로고    scopus 로고
    • Transposon-mediated BAC transgenesis in zebrafish and mice.
    • 10.1186/1471-2164-10-477, 2768751, 19832998
    • Suster ML, Sumiyama K, Kawakami K. Transposon-mediated BAC transgenesis in zebrafish and mice. BMC Genomics 2009, 10:477. 10.1186/1471-2164-10-477, 2768751, 19832998.
    • (2009) BMC Genomics , vol.10 , pp. 477
    • Suster, M.L.1    Sumiyama, K.2    Kawakami, K.3
  • 65
    • 34347337601 scopus 로고    scopus 로고
    • Toward simpler and faster genome-wide mutagenesis in mice.
    • 10.1038/ng2060, 17572674
    • Wu S, Ying G, Wu Q, Capecchi MR. Toward simpler and faster genome-wide mutagenesis in mice. Nat Genet 2007, 39:922-930. 10.1038/ng2060, 17572674.
    • (2007) Nat Genet , vol.39 , pp. 922-930
    • Wu, S.1    Ying, G.2    Wu, Q.3    Capecchi, M.R.4
  • 66
    • 64749111225 scopus 로고    scopus 로고
    • Virus-free induction of pluripotency and subsequent excision of reprogramming factors.
    • 10.1038/nature07864, 2667910, 19252477
    • Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K. Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 2009, 458:771-775. 10.1038/nature07864, 2667910, 19252477.
    • (2009) Nature , vol.458 , pp. 771-775
    • Kaji, K.1    Norrby, K.2    Paca, A.3    Mileikovsky, M.4    Mohseni, P.5    Woltjen, K.6
  • 67
    • 65449154892 scopus 로고    scopus 로고
    • Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon.
    • 10.1038/nmeth.1323, 2677165, 19337237
    • Yusa K, Rad R, Takeda J, Bradley A. Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon. Nat Methods 2009, 6:363-369. 10.1038/nmeth.1323, 2677165, 19337237.
    • (2009) Nat Methods , vol.6 , pp. 363-369
    • Yusa, K.1    Rad, R.2    Takeda, J.3    Bradley, A.4
  • 68
    • 77955379516 scopus 로고    scopus 로고
    • Gene trap mutagenesis in the mouse.
    • Friedel RH, Soriano P. Gene trap mutagenesis in the mouse. Methods Enzymol 2010, 477:243-269.
    • (2010) Methods Enzymol , vol.477 , pp. 243-269
    • Friedel, R.H.1    Soriano, P.2
  • 69
    • 84934435818 scopus 로고    scopus 로고
    • Conditional gene trapping using the FLEx system.
    • 10.1007/978-1-59745-232-8_9, 18370072
    • Floss T, Schnutgen F. Conditional gene trapping using the FLEx system. Methods Mol Biol 2008, 435:127-138. 10.1007/978-1-59745-232-8_9, 18370072.
    • (2008) Methods Mol Biol , vol.435 , pp. 127-138
    • Floss, T.1    Schnutgen, F.2
  • 70
    • 0027099866 scopus 로고
    • Enhancer trap integrations in mouse embryonic stem cells give rise to staining patterns in chimaeric embryos with a high frequency and detect endogenous genes.
    • 10.1016/0925-4773(92)90029-J, 1283314
    • Korn R, Schoor M, Neuhaus H, Henseling U, Soininen R, Zachgo J, Gossler A. Enhancer trap integrations in mouse embryonic stem cells give rise to staining patterns in chimaeric embryos with a high frequency and detect endogenous genes. Mech Dev 1992, 39:95-109. 10.1016/0925-4773(92)90029-J, 1283314.
    • (1992) Mech Dev , vol.39 , pp. 95-109
    • Korn, R.1    Schoor, M.2    Neuhaus, H.3    Henseling, U.4    Soininen, R.5    Zachgo, J.6    Gossler, A.7
  • 71
    • 0029926149 scopus 로고    scopus 로고
    • An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro.
    • 10.1073/pnas.93.4.1677, 40001, 8643689
    • Forrester LM, Nagy A, Sam M, Watt A, Stevenson L, Bernstein A, Joyner AL, Wurst W. An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proc Natl Acad Sci USA 1996, 93:1677-1682. 10.1073/pnas.93.4.1677, 40001, 8643689.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1677-1682
    • Forrester, L.M.1    Nagy, A.2    Sam, M.3    Watt, A.4    Stevenson, L.5    Bernstein, A.6    Joyner, A.L.7    Wurst, W.8
  • 72
    • 3242768444 scopus 로고    scopus 로고
    • Gene-trap expression screening to identify endothelial-specific genes.
    • 10.1182/blood-2004-01-0254, 15090446
    • Hirashima M, Bernstein A, Stanford WL, Rossant J. Gene-trap expression screening to identify endothelial-specific genes. Blood 2004, 104:711-718. 10.1182/blood-2004-01-0254, 15090446.
    • (2004) Blood , vol.104 , pp. 711-718
    • Hirashima, M.1    Bernstein, A.2    Stanford, W.L.3    Rossant, J.4
  • 73
    • 3042531072 scopus 로고    scopus 로고
    • Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cells.
    • 10.1038/nature02653, 15215866
    • Guo G, Wang W, Bradley A. Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cells. Nature 2004, 429:891-895. 10.1038/nature02653, 15215866.
    • (2004) Nature , vol.429 , pp. 891-895
    • Guo, G.1    Wang, W.2    Bradley, A.3
  • 76
    • 79955561070 scopus 로고    scopus 로고
    • Reversible suppression of an essential gene in adult mice using transgenic RNA interference.
    • 10.1073/pnas.1104097108, 3084121, 21482754
    • McJunkin K, Mazurek A, Premsrirut PK, Zuber J, Dow LE, Simon J, Stillman B, Lowe SW. Reversible suppression of an essential gene in adult mice using transgenic RNA interference. Proc Natl Acad Sci USA 2011, 108:7113-7118. 10.1073/pnas.1104097108, 3084121, 21482754.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 7113-7118
    • McJunkin, K.1    Mazurek, A.2    Premsrirut, P.K.3    Zuber, J.4    Dow, L.E.5    Simon, J.6    Stillman, B.7    Lowe, S.W.8
  • 78
    • 18844392836 scopus 로고    scopus 로고
    • Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues.
    • 10.1016/j.cell.2005.02.018, 15882627
    • Hochedlinger K, Yamada Y, Beard C, Jaenisch R. Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 2005, 121:465-477. 10.1016/j.cell.2005.02.018, 15882627.
    • (2005) Cell , vol.121 , pp. 465-477
    • Hochedlinger, K.1    Yamada, Y.2    Beard, C.3    Jaenisch, R.4
  • 81
    • 27644501458 scopus 로고    scopus 로고
    • EMPReSS: standardized phenotype screens for functional annotation of the mouse genome.
    • 10.1038/ng1105-1155, 16254554
    • Brown SD, Chambon P, de Angelis MH. EMPReSS: standardized phenotype screens for functional annotation of the mouse genome. Nat Genet 2005, 37:1155. 10.1038/ng1105-1155, 16254554.
    • (2005) Nat Genet , vol.37 , pp. 1155
    • Brown, S.D.1    Chambon, P.2    de Angelis, M.H.3
  • 83
    • 7744221326 scopus 로고    scopus 로고
    • The Mouse Phenome Project.
    • 10.1007/s10709-004-1438-4, 15619963
    • Bogue MA, Grubb SC. The Mouse Phenome Project. Genetica 2004, 122:71-74. 10.1007/s10709-004-1438-4, 15619963.
    • (2004) Genetica , vol.122 , pp. 71-74
    • Bogue, M.A.1    Grubb, S.C.2
  • 89
    • 0036215090 scopus 로고    scopus 로고
    • Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort.
    • 10.1007/s00335-001-4001-y, 11956758
    • Threadgill DW, Hunter KW, Williams RW. Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort. Mamm Genome 2002, 13:175-178. 10.1007/s00335-001-4001-y, 11956758.
    • (2002) Mamm Genome , vol.13 , pp. 175-178
    • Threadgill, D.W.1    Hunter, K.W.2    Williams, R.W.3
  • 91
    • 49549092476 scopus 로고    scopus 로고
    • Mapping multiprotein complexes by affinity purification and mass spectrometry.
    • 10.1016/j.copbio.2008.06.002, 18598764
    • Collins MO, Choudhary JS. Mapping multiprotein complexes by affinity purification and mass spectrometry. Curr Opin Biotechnol 2008, 19:324-330. 10.1016/j.copbio.2008.06.002, 18598764.
    • (2008) Curr Opin Biotechnol , vol.19 , pp. 324-330
    • Collins, M.O.1    Choudhary, J.S.2
  • 93
    • 78751676589 scopus 로고    scopus 로고
    • A new technique for controlling the brain: optogenetics and its potential for use in research and the clinic.
    • 10.1016/j.brs.2010.09.009, 21255749
    • LaLumiere RT. A new technique for controlling the brain: optogenetics and its potential for use in research and the clinic. Brain Stimul 2011, 4:1-6. 10.1016/j.brs.2010.09.009, 21255749.
    • (2011) Brain Stimul , vol.4 , pp. 1-6
    • LaLumiere, R.T.1
  • 95
    • 79951992387 scopus 로고    scopus 로고
    • AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training.
    • 10.1038/nn.2739, 21209617
    • Aponte Y, Atasoy D, Sternson SM. AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training. Nat Neurosci 2011, 14:351-355. 10.1038/nn.2739, 21209617.
    • (2011) Nat Neurosci , vol.14 , pp. 351-355
    • Aponte, Y.1    Atasoy, D.2    Sternson, S.M.3
  • 96
    • 54749096446 scopus 로고    scopus 로고
    • Species specificity in major urinary proteins by parallel evolution.
    • 10.1371/journal.pone.0003280, 2533699, 18815613
    • Logan DW, Marton TF, Stowers L. Species specificity in major urinary proteins by parallel evolution. PLoS ONE 2008, 3:e3280. 10.1371/journal.pone.0003280, 2533699, 18815613.
    • (2008) PLoS ONE , vol.3
    • Logan, D.W.1    Marton, T.F.2    Stowers, L.3
  • 97
    • 0343179029 scopus 로고
    • Simian virus 40 DNA sequences in DNA of healthy adult mice derived from preimplantation blastocysts injected with viral DNA.
    • 10.1073/pnas.71.4.1250, 388203, 4364530
    • Jaenisch R, Mintz B. Simian virus 40 DNA sequences in DNA of healthy adult mice derived from preimplantation blastocysts injected with viral DNA. Proc Natl Acad Sci USA 1974, 71:1250-1254. 10.1073/pnas.71.4.1250, 388203, 4364530.
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 1250-1254
    • Jaenisch, R.1    Mintz, B.2
  • 98
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector.
    • 10.1126/science.272.5259.263, 8602510
    • Naldini L, Blomer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996, 272:263-267. 10.1126/science.272.5259.263, 8602510.
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1    Blomer, U.2    Gallay, P.3    Ory, D.4    Mulligan, R.5    Gage, F.H.6    Verma, I.M.7    Trono, D.8
  • 99
    • 65549092808 scopus 로고    scopus 로고
    • Lentiviral transgenesis.
    • 10.1007/978-1-59745-471-1_21, 19266335
    • Pfeifer A, Hofmann A. Lentiviral transgenesis. Methods Mol Biol 2009, 530:391-405. 10.1007/978-1-59745-471-1_21, 19266335.
    • (2009) Methods Mol Biol , vol.530 , pp. 391-405
    • Pfeifer, A.1    Hofmann, A.2
  • 100
    • 37549055397 scopus 로고    scopus 로고
    • Efficient in vivo targeting of epidermal stem cells by early gestational intraamniotic injection of lentiviral vector driven by the keratin 5 promoter.
    • 10.1038/sj.mt.6300332, 17923841
    • Endo M, Zoltick PW, Peranteau WH, Radu A, Muvarak N, Ito M, Yang Z, Cotsarelis G, Flake AW. Efficient in vivo targeting of epidermal stem cells by early gestational intraamniotic injection of lentiviral vector driven by the keratin 5 promoter. Mol Ther 2008, 16:131-137. 10.1038/sj.mt.6300332, 17923841.
    • (2008) Mol Ther , vol.16 , pp. 131-137
    • Endo, M.1    Zoltick, P.W.2    Peranteau, W.H.3    Radu, A.4    Muvarak, N.5    Ito, M.6    Yang, Z.7    Cotsarelis, G.8    Flake, A.W.9
  • 101
    • 0037235453 scopus 로고    scopus 로고
    • Retroviral insertional mutagenesis: tagging cancer pathways.
    • Mikkers H, Berns A. Retroviral insertional mutagenesis: tagging cancer pathways. Adv Cancer Res 2003, 88:53-99.
    • (2003) Adv Cancer Res , vol.88 , pp. 53-99
    • Mikkers, H.1    Berns, A.2
  • 102
    • 27944496521 scopus 로고    scopus 로고
    • Retroviral insertional mutagenesis: past, present and future.
    • 10.1038/sj.onc.1209043, 16299527
    • Uren AG, Kool J, Berns A, van Lohuizen M. Retroviral insertional mutagenesis: past, present and future. Oncogene 2005, 24:7656-7672. 10.1038/sj.onc.1209043, 16299527.
    • (2005) Oncogene , vol.24 , pp. 7656-7672
    • Uren, A.G.1    Kool, J.2    Berns, A.3    van Lohuizen, M.4
  • 104
    • 0023150598 scopus 로고
    • HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells.
    • 10.1038/326292a0, 3821905
    • Hooper M, Hardy K, Handyside A, Hunter S, Monk M. HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature 1987, 326:292-295. 10.1038/326292a0, 3821905.
    • (1987) Nature , vol.326 , pp. 292-295
    • Hooper, M.1    Hardy, K.2    Handyside, A.3    Hunter, S.4    Monk, M.5
  • 105
    • 0029562967 scopus 로고
    • Chromosome engineering in mice.
    • 10.1038/378720a0, 7501018
    • Ramirez-Solis R, Liu P, Bradley A. Chromosome engineering in mice. Nature 1995, 378:720-724. 10.1038/378720a0, 7501018.
    • (1995) Nature , vol.378 , pp. 720-724
    • Ramirez-Solis, R.1    Liu, P.2    Bradley, A.3
  • 106
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality.
    • 10.1016/0092-8674(92)90611-F, 1606615
    • Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992, 69:915-926. 10.1016/0092-8674(92)90611-F, 1606615.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 107
    • 0027264498 scopus 로고
    • Targeted disruption of the MHC class II Aa gene in C57BL/6 mice.
    • 10.1093/intimm/5.8.957, 8398989
    • Kontgen F, Suss G, Stewart C, Steinmetz M, Bluethmann H. Targeted disruption of the MHC class II Aa gene in C57BL/6 mice. Int Immunol 1993, 5:957-964. 10.1093/intimm/5.8.957, 8398989.
    • (1993) Int Immunol , vol.5 , pp. 957-964
    • Kontgen, F.1    Suss, G.2    Stewart, C.3    Steinmetz, M.4    Bluethmann, H.5
  • 108
    • 77956195155 scopus 로고    scopus 로고
    • Efficient generation of germ line transmitting chimeras from C57BL/6N ES cells by aggregation with outbred host embryos.
    • 10.1371/journal.pone.0011260, 2889837, 20582321
    • Gertsenstein M, Nutter LM, Reid T, Pereira M, Stanford WL, Rossant J, Nagy A. Efficient generation of germ line transmitting chimeras from C57BL/6N ES cells by aggregation with outbred host embryos. PLoS One 2010, 5:e11260. 10.1371/journal.pone.0011260, 2889837, 20582321.
    • (2010) PLoS One , vol.5
    • Gertsenstein, M.1    Nutter, L.M.2    Reid, T.3    Pereira, M.4    Stanford, W.L.5    Rossant, J.6    Nagy, A.7
  • 109
    • 0027321548 scopus 로고
    • Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.
    • 10.1073/pnas.90.18.8424, 47369, 8378314
    • Nagy A, Rossant J, Nagy R, Abramow-Newerly W, Roder JC. Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. Proc Natl Acad Sci USA 1993, 90:8424-8428. 10.1073/pnas.90.18.8424, 47369, 8378314.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8424-8428
    • Nagy, A.1    Rossant, J.2    Nagy, R.3    Abramow-Newerly, W.4    Roder, J.C.5
  • 115
    • 38549105490 scopus 로고    scopus 로고
    • EuroPhenome and EMPReSS: online mouse phenotyping resource.
    • 2238991, 17905814
    • Mallon AM, Blake A, Hancock JM. EuroPhenome and EMPReSS: online mouse phenotyping resource. Nucleic Acids Res 2008, 36:D715-D718. 2238991, 17905814.
    • (2008) Nucleic Acids Res , vol.36
    • Mallon, A.M.1    Blake, A.2    Hancock, J.M.3
  • 116
    • 33745737474 scopus 로고    scopus 로고
    • FIMRe: Federation of International Mouse Resources: global networking of resource centers.
    • 10.1007/s00335-006-0001-2, 16688526
    • Davisson M. FIMRe: Federation of International Mouse Resources: global networking of resource centers. Mamm Genome 2006, 17:363-364. 10.1007/s00335-006-0001-2, 16688526.
    • (2006) Mamm Genome , vol.17 , pp. 363-364
    • Davisson, M.1
  • 117
    • 65549142250 scopus 로고    scopus 로고
    • International Gene Trap Project: towards gene-driven saturation mutagenesis in mice.
    • 10.2174/138920109787315006, 19199955
    • Araki M, Araki K, Yamamura K. International Gene Trap Project: towards gene-driven saturation mutagenesis in mice. Curr Pharm Biotechnol 2009, 10:221-229. 10.2174/138920109787315006, 19199955.
    • (2009) Curr Pharm Biotechnol , vol.10 , pp. 221-229
    • Araki, M.1    Araki, K.2    Yamamura, K.3
  • 119
    • 78651286166 scopus 로고    scopus 로고
    • The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics.
    • 10.1093/nar/gkq1008, 3013640, 21051359
    • Blake JA, Bult CJ, Kadin JA, Richardson JE, Eppig JT. The Mouse Genome Database (MGD): premier model organism resource for mammalian genomics and genetics. Nucleic Acids Res 2011, 39:D842-848. 10.1093/nar/gkq1008, 3013640, 21051359.
    • (2011) Nucleic Acids Res , vol.39
    • Blake, J.A.1    Bult, C.J.2    Kadin, J.A.3    Richardson, J.E.4    Eppig, J.T.5


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