Modulation of human recombinant GABA(A) receptors by pregnanediols

Neuropharmacology

Volumn 35, Issue 9-10, 1996, Pages 1223-1231

  Belelli, D ^a   Lambert, J J ^a   Peters, J A ^a   Gee, K W ^b   Lan, N C ^c  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Department of Pharmacokinetics and Drug Metabolism   (United States)

Author keywords

Anxiolytic; General anaesthetics; Human recombinant GABA(A) receptors; Neurosteroids; Pregnanediols; Xenopus laevis oocytes

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 5ALPHA PREGNANE 3ALPHA,20ALPHA DIOL; 5ALPHA PREGNANE 3ALPHA,20BETA DIOL; 5BETA PREGNANE 3ALPHA,20BETA DIOL; ANESTHETIC AGENT; BRETAZENIL; DIAZEPAM; ELTANOLONE; NEUROSTEROID; PENTOBARBITAL; PREGNANEDIOL; RECEPTOR SUBUNIT; RECOMBINANT RECEPTOR; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG POTENTIATION; FEMALE; GENE EXPRESSION; HUMAN; MEMBRANE CURRENT; NEUROMODULATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; XENOPUS LAEVIS;

ANESTHETICS, GENERAL; ANIMALS; ELECTROPHYSIOLOGY; GABA MODULATORS; HUMANS; MEMBRANE POTENTIALS; OOCYTES; PATCH-CLAMP TECHNIQUES; PREGNANEDIOL; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 0030459355     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(96)00066-4     Document Type: Article

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