Two 17β-hydroxysteroid dehydrogenases (17HSDs) of estradiol biosynthesis: 17HSD type 1 and type 7

Journal of Steroid Biochemistry and Molecular Biology

Volumn 69, Issue 1-6, 1999, Pages 431-439

  Peltoketo, Hellevi ^a   Nokelainen, Pasi ^a   Piao, Yun Shang ^a   Vihko, Reijo ^a   Vihko, Pirkko ^a,b  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ISOENZYME; PROLACTIN RECEPTOR; RECEPTOR PROTEIN; TESTOSTERONE 17BETA DEHYDROGENASE; 3 (OR 17) BETA HYDROXYSTEROID DEHYDROGENASE; 3 (OR 17)-BETA-HYDROXYSTEROID DEHYDROGENASE; COMPLEMENTARY DNA; HYDROXYSTEROID DEHYDROGENASE;

AMINO ACID SEQUENCE; BINDING SITE; CATALYSIS; CONFERENCE PAPER; CORPUS LUTEUM; ENHANCER REGION; ENZYME ACTIVITY; ESTROGEN SYNTHESIS; GRANULOSA CELL; HORMONE RESPONSIVE ELEMENT; LUTEAL CELL; OVARY; PREGNANCY; PROMOTER REGION; PROTEIN EXPRESSION; SILENCER GENE; TISSUE SPECIFICITY; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; REVIEW;

17-HYDROXYSTEROID DEHYDROGENASES; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA, COMPLEMENTARY; ESTRADIOL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; ISOENZYMES; MOLECULAR SEQUENCE DATA;

EID: 0032588918     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(99)00064-3     Document Type: Conference Paper

References (46)

1. Simpson E.R., Mahendroo M.S., Means G.D., Kilgore W., Hinshelwood M.M., Graham-Lawrence S., Amarneh B., Ito Y., Fisher C.R., Michael M.D., Mendelson C.R., Bulun S.E. Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis. Endocr. Rev. 15:1994;342-355.
2. Ghersevich S., Nokelainen P., Poutanen M., Orava M., Autio-Harmainen H., Rajaniemi H., Vihko R. Rat 17β-hydroxysteroid dehydrogenase type 1: primary structure and regulation of enzyme expression in rat ovary by diethylstilbestrol and gonadotropins in vivo. Endrocrinology. 135:1994;1477-1487.
3. Sawetawan C., Milewich L., Word R.A., Carr B.R., Rainey W.E. Compartmentalization of type I 17β-hydroxysteroid oxidoreductase in the human ovary. Molec. Cell. Endocr. 99:1994;161-168.
4. Gibori G. The corpus luteum of pregnancy. Adashi E.Y., Leung P.C.K. The Ovary. 1993;261-317 Raven Press, New York.
5. Fournet-Dulguerov N., MacLusky N.J., Leranth C.Z., Todd R., Mendelson C.R., Simpson E.R., Naftolin F. Immunohistochemical localization of aromatase cytochrome P-450 and estradiol dehydrogenase in the syncytiotrophoblast of human placenta. J. Clin. Endocr. Metab. 65:1987;757-764.
6. Akinola L.A., Poutanen M., Vihko R., Vihko P. Expression of 17β-hydroxysteroid dehydrogenase type 1 and type 2, P450 aromatase and 20α-hydroxysteroid dehydrogenase enzymes in immature, mature and pregnant rats. Endocrinology. 138:1997;2886-2892.
7. Taya K., Greenwald G.S. In vivo and in vitro ovarian steroidogenesis in the pregnant rat. Biol. Reprod. 25:1981;683-691.
8. Nokelainen P., Peltoketo H., Vihko R., Vihko P. Expression cloning of a novel estrogenic mouse 17β-hydroxysteroid dehydrogenase/17-ketosteroid reductase (m17HSD7), previously described as a prolactin receptor-associated protein (PRAP) in rat. Molec. Endocr. 12:1998;1048-1059.
9. Ball R.K., Friis R.R., Schoenenberger C.A., Doppler W., Groner B. Prolactin regulation of β-casein gene expression and of a cytosolic 120-kd protein in a cloned mouse mammary epithelial cell line. EMBO J. 7:1988;2089-2095.
10. Nokelainen P., Puranen T., Peltoketo H., Orava M., Vihko P., Vihko R. Molecular cloning of mouse 17β-hydroxysteroid dehydrogenase type 1 and characterization of enzyme activity. Eur. J. Biochem. 236:1996;482-490.
11. Jörnvall H., Persson B., Krook M., Atrian S., Gonzàlez-Duarte R., Jeffery J., Ghosh D. Short-chain dehydrogenase/reductases (SDR). Biochemistry. 34:1995;6003-6013.
12. Ghosh D., Pletnev V.Z., Zhu D-W., Wawrzak Z., Duax W.L., Pangborn W., Labrie F., Lin S-X. Structure of human estrogenic 17β-hydroxysteroid dehydrogenase at 2.20 Å resolution. Structure. 3:1995;503-513.
13. Duan W.R., Linzer D.I.H., Gibori G. Cloning and characterization of an ovarian-specific protein that associates with the short form of the prolactin receptor. J. Biol. Chem. 271:1996;15602-15607.
14. Parmer T.G., McLean M.P., Duan W.R., Nelson S.E., Albarracin C.T., Khan I., Gibori G. Hormonal and immunological characterization of the 32 kilodalton ovarian-specific protein. Endocrinology. 131:1992;2213-2221.
15. Duan W.R., Parmer T.G., Albarracin C.T., Zhong L., Gibori G. PRAP, a prolactin receptor associated protein: its gene expression and regulation in the corpus luteum. Endocrinology. 138:1997;3216-3221.
16. Puranen T., Poutanen M., Ghosh D., Vihko P., Vihko R. Characterization of structural and functional properties of human 17β-hydroxysteroid dehydrogenase type 1 using recombinant enzymes and site-directed mutagenesis. Molec. Endocr. 11:1997;77-86.
17. Puranen T., Poutanen M., Ghosh D., Vihko R., Vihko P. Origin of substrate specificity of human and rat 17β-hydroxysteroid dehydrogenase type 1, using chimeric enzymes and site-directed substitutions. Endocrinology. 138:1997;3532-3539.
18. Hickey G.J., Chen S., Besman M.J., Shively J.E., Hall P.F., Gaddy-Kurten D., Richards J.S. Hormonal regulation, tissue distribution, and content of aromatase cytochrome P450 messenger ribonucleic acid and enzyme in rat ovarian follicles and corpora lutea: relationship to estradiol biosynthesis. Endocrinology. 122:1988;1426-1436.
19. Telleria C.M., Parmer T.G., Zhong L., Clarke D.L., Albarracin C.T., Duan W.R., Linzer D.I.H., Gibori G. The different forms of the prolactin receptor in the rat corpus luteum: developmental expression and hormonal regulation in pregnancy. Endocrinology. 138:1997;4812-4820.
20. Miettinen M.M., Poutanen M.H., Vihko R.K. Characterization of estrogen-dependent growth of cultured MCF-7 human breast cancer cells expressing 17β-hydroxysteroid dehydrogenase type 1. Int. J. Cancer. 68:1996;600-604.
21. Rembiesa R., Marchut M., Warchol A. Formation and metabolism of progesterone by the mouse placenta in vitro. J. Steroid Biochem. 2:1971;111-119.
22. Mustonen M., Poutanen M., Chotteau-Lelievre A., de Launoit Y., Isomaa V., Vainio S., Vihko R., Vihko P. Ontogeny of 17β-hydroxysteroid dehydrogenase type 2 mRNA expression in the developing mouse placenta and fetus. Molec. Cell. Endocr. 134:1997;33-40.
23. Moghrabi N., Head J.R., Andersson S. Cell type-specific expression of 17β-hydroxysteroid dehydrogenase type 2 in human placenta and fetal liver. J. Clin. Endocr. Metab. 82:1997;3872-3878.
24. Ghersevich S., Poutanen M., Tapanainen J., Vihko R. Hormonal regulation of rat 17β-hydroxysteroid dehydrogenase type 1 in cultured rat granulosa cells: effects of recombinant follicle-stimulating hormone, estrogens, androgens, and epidermal growth factor. Endocrinology. 135:1994;1963-1971.
25. Kaminski T., Akinola L.A., Poutanen M., Vihko R., Vihko P. Growth factors and phorbol-12-myristate-13-acetate modulate the follicle-stimulating hormone- and cyclic adenosine-3′,5′-monophosphate dependent regulation of 17β-hydroxysteroid dehydrogenase type 1 expression in rat granulosa cells. Molec. Cell. Endocr. 136:1997;47-56.
26. Piao Y-S., Peltoketo H., Jouppila A., Vihko R. Retinoic acids increase 17β-hydroxysteroid dehydrogenase type 1 expression in JEG-3 and T-47D cells, but the stimulation is potentiated by epidermal growth factor, 12-O-tetradecanoylphorbol-13-acetate, and cyclic adenosine 3′,5′-monophosphate only in JEG-3 cells. Endocrinology. 138:1997;898-904.
27. Luu-The V., Labrie C., Zhao H.F., Couët J., Lachance Y., Simard J., Leblanc G., Côté J., Bérubé D., Gagné R., Labrie F. Characterization of cDNAs for human estradiol 17β-dehydrogenase and assignment of the gene to chromosome 17: evidence of two mRNA species with distinct 5′-termini in human placenta. Molec. Endocr. 3:1989;1301-1309.
28. Luu-The V., Labrie C., Simard J., Lachance Y., Zhao H-F., Couët J., Leblanc G., Labrie F. Structure of two in tandem human 17β-hydroxysteroid dehydrogenase genes. Molec. Endocr. 4:1990;268-275.
29. Tremblay Y., Ringler G.E., More Y., Mohandas T.K., Labrie F., Strauss J.F. III, Miller W.L. Regulation of the gene for estrogenic 17-ketosteroid reductase lying on chromosome 17cen→q25. J. Biol. Chem. 264:1989;20458-20462.
30. Miettinen M.M., Mustonen M.V.J., Poutanen M.H., Isomaa V.V., Vihko R.K. Human 17β-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression. Biochem. J. 314:1996;839-845.
31. Poutanen M., Moncharmont B., Vihko R. 17β-Hydroxysteroid dehydrogenase gene expression in human breast cancer cells, regulation of expression by a progestin. Cancer Res. 52:1992;290-294.
32. Reed M.J., Rea D., Duncan L.J., Parker M.G. Regulation of estradiol 17β-hydroxysteroid dehydrogenase expression and activity by retinoic acid in T47D breast cancer cells. Endrocrinology. 135:1994;4-9.
33. Akinola L.A., Poutanen M., Vihko R. Cloning of rat 17β-hydroxysteroid dehydrogenase type 2 and characterization of tissue distribution and catalytic activity of rat type 1 and type 2 enzymes. Endocrinology. 137:1996;1572-1579.
34. Akinola L.A., Poutanen M., Peltoketo H., Vihko R., Vihko P. Characterization of rat 17β-hydroxysteroid dehydrogenase type 1 gene and mRNA transcripts. Gene. 208:1997;229-238.
35. Piao Y., Peltoketo H., Oikarinen J., Vihko R. Coordination of transcription of the human 17β-hydroxysteroid dehydrogenase type 1 gene (EDH17B2) by a cell-specific enhancer and a silencer: identification of a retinoic acid response element. Molec. Endocr. 9:1995;1633-1644.
36. Piao Y-S., Peltoketo H., Vihko P., Vihko R. The proximal promoter region of the gene encoding human 17β-hydroxysteroid dehydrogenase type 1 contains GATA, AP-2 and Sp1 response elements: analysis of promoter function in choriocarcinoma cells. Endocrinology. 138:1997;3417-3425.
37. Peltoketo H., Isomaa V., Poutanen M., Vihko R. Expression and regulation of 17β-hydroxysteroid dehydrogenase type 1. J. Endocr. 150:1996;S21-S30.
38. Peltoketo H., Isomaa V., Vihko R. Genomic organization and DNA sequences of human 17β-hydroxysteroid dehydrogenase genes and flanking regions: localization of multiple Alu sequences and putative cis-acting elements. Eur. J. Biochem. 209:1992;459-466.
39. Hagen G., Müller S., Beato M., Suske G. Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res. 20:1992;5519-5525.
40. Lecointe N., Bernard O., Naert K., Joulin V., Larsen C.J., Romeo P.H., Mathieu-Mahul D. GATA- and Sp1-binding sites are required for the full activity of the tissue-specific promoter of the tal-1 gene. Oncogene. 9:1994;2623-2632.
41. Ström A-C., Forsberg M., Lillhager P., Westin G. The transcription factors Sp1 and Oct-1 interact physically to regulate human U1 snRNA gene expression. Nucleic Acids Res. 24:1996;1981-1986.
42. Jiang S-W., Shepard A.R., Eberhardt N.L. An initiator element is required for maximal human chorionic somatomammotropin gene promoter and enhancer function. J. Biol. Chem. 270:1995;3683-3692.
43. Hagen G., Müller S., Beato M., Suske G. Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J. 13:1994;3843-3851.
44. Dennig J., Beato M., Suske G. An inhibitor domain in Sp3 regulates its glutamine-rich activation domains. EMBO J. 15:1996;5659-5667.
45. Imagawa M., Chiu R., Karin M. Transcription factor AP-2 mediates induction by two different signal-transduction pathway: protein kinase C and cAMP. Cell. 51:1987;251-260.
46. Ng Y-K., George K.M., Engel J.D., Linzer D.I.H. GATA factor activity is required for the trophoblast-specific transcriptional regulation of the mouse placental lactogen I gene. Development. 120:1994;3257-3266.