Ataxia telangiectasia mutated- and Rad3-related kinase drives both the early and the late DNA-damage response to the monofunctional antitumour alkylator S23906

Biochemical Journal

Volumn 437, Issue 1, 2011, Pages 63-73

  Soares, Daniele G ^a,b,c   Battistella, Aude ^a,b,c   Rocca, Céline J ^a,b,c   Matuo, Renata ^a,b,c,d   Henriques, João A P ^d,e   Larsen, Annette K ^a,b,c   Escargueil, Alexandre E ^a,b,c  

^a CENTRE DE RECHERCHE SAINT ANTOINE   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c INSERM   (France)

^d FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^e UNIVERSITY OF CAXIAS DO SUL   (Brazil)

Author keywords

Checkpoint control; DNA alkylator; DNA replication; DNA damage response

Indexed keywords

ACRONINE; ATR PROTEIN; AZD7762; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; DNA; ENZYME INHIBITOR; HISTONE H2AX; REPLICATION FACTOR A; S23906; UNCLASSIFIED DRUG;

ARTICLE; ATTENUATION; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG EXPOSURE; DRUG POTENTIATION; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ACRONINE; ANTINEOPLASTIC AGENTS, ALKYLATING; CELL CYCLE PROTEINS; DNA DAMAGE; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; HELA CELLS; HISTONES; HUMANS; MICROSCOPY, FLUORESCENCE; MUTATION; NUCLEAR PROTEINS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; REPLICATION PROTEIN A; THIOPHENES; UREA;

ATAXIA TELANGIECTASIA;

EID: 79958796308     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101770     Document Type: Article

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