Induction of cyclin E and inhibition of DNA synthesis by the novel acronycine derivative S23906-1 precede the irreversible arrest of tumor cells in S phase leading to apoptosis

Molecular Pharmacology

Volumn 60, Issue 6, 2001, Pages 1383-1391

  Leonce S ^a   Perez V ^a   Lambel, S ^a   Peyroulan, D ^a   Tillequin, F ^a   Michel, S ^a   Koch, M ^a   Pfeiffer, B ^a   Atassi, G ^a   Hickman, J A ^a   Pierre A ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACRONINE; BROXURIDINE; CARMUSTINE; CISPLATIN; CYCLIN D1; CYCLIN D2; CYCLIN D3; CYCLIN DEPENDENT KINASE 2; CYCLIN E; CYTARABINE; CYTOTOXIC AGENT; DNA; FLUOROURACIL; GEMCITABINE; LIPOCORTIN 5; METHOTREXATE; S 23906 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL SURVIVAL; CLONOGENIC ASSAY; CYTOTOXICITY; DNA CONTENT; DNA DAMAGE; DNA SYNTHESIS INHIBITION; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN INDUCTION; TUMOR CELL; TUMOR CELL CULTURE; WESTERN BLOTTING;

EID: 0035213896     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.60.6.1383     Document Type: Article

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