Generation of replication-dependent double-strand breaks by the novel N2-G-alkylator S23906-1

Cancer Research

Volumn 66, Issue 14, 2006, Pages 7203-7210

  Léonce, Stéphane ^a   Kraus Berthier, Laurence ^a   Golsteyn, Roy M ^a   David Cordonnier, Marie Hélène ^b   Tardy, Christelle ^b   Lansiaux, Amélie ^b   Poindessous, Virginie ^b   Larsen, Annette K ^b   Pierré, Alain ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

^b INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; APHIDICOLIN; CAMPTOTHECIN; CHECKPOINT KINASE 2; CISPLATIN; CYTARABINE; DOXORUBICIN; ETOPOSIDE; GLYCOPROTEIN P; HISTONE H2AX; MITOMYCIN C; PACLITAXEL; S 23906 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL DEATH; CELL DIVISION; CELL LINE; COMET ASSAY; CONTROLLED STUDY; CROSS RESISTANCE; CYTOTOXICITY; DNA ADDUCT; DNA ALKYLATION; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND BREAKAGE; DOSE TIME EFFECT RELATION; DRUG INHIBITION; DRUG MECHANISM; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ACRONINE; ALKYLATION; CARCINOMA, SQUAMOUS CELL; CELL CYCLE; DNA DAMAGE; DNA, NEOPLASM; HISTONES; HUMANS; KB CELLS; P-GLYCOPROTEIN; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES;

EID: 33746910897     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-3946     Document Type: Article

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