The sushi domains of secreted GABAB1 isoforms selectively impair GABAB heteroreceptor function

Journal of Biological Chemistry

Volumn 283, Issue 45, 2008, Pages 31005-31011

  Tiao, Jim Y ^a   Bradaia, Amyaouch ^a   Biermann, Barbara ^a   Kaupmann, Klemens ^b   Metz, Michaela ^a   Haller, Corinne ^a   Rolink, Antonius G ^a   Pless, Elin ^c   Barlow, Paul N ^c   Gassmann, Martin ^a   Bettler, Bernhard ^a,d  

^a UNIVERSITY OF BASEL   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d Pharmazentrum   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; MACHINERY; PORT TERMINALS;

AMINOBUTYRIC ACIDS; BINDING PARTNERS; COUPLED RECEPTORS; DO-MAINS; DRUG DISCOVERIES; DRUG TARGETS; ECTODOMAIN; EXTRACELLULAR; GABAERGIC; HIPPOCAMPAL NEURONS; HIPPOCAMPAL SLICES; INHIBITORY EFFECTS; ISOFORM; ISOFORMS; NANOMOLAR AFFINITIES; NANOMOLAR CONCENTRATIONS; NEURO-TRANSMITTERS; NEUROLOGICAL DISORDERS; NEURONAL MEMBRANES; PHARMACOLOGICAL DIFFERENCES; POSTSYNAPTIC RECEPTORS; PRESYNAPTIC; PROTEIN BINDINGS; SOLUBLE PROTEINS; WIDE SPECTRUMS;

DIFFUSERS (OPTICAL);

4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B1A RECEPTOR; 4 AMINOBUTYRIC ACID B1B RECEPTOR; AUTORECEPTOR; GLUTAMIC ACID; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; EMBRYO; HIPPOCAMPUS; HUMAN; HUMAN CELL; MOUSE; NERVE FIBER; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SUSHI DOMAIN;

AMINO ACID MOTIFS; ANIMALS; BASE SEQUENCE; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PRESYNAPTIC TERMINALS; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, GABA-B; SYNAPTIC MEMBRANES;

EID: 57649223726     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M804464200     Document Type: Article

References (39)

1. Bettler, B., Kaupmann, K., Mosbacher, J., and Gassmann, M. (2004) Physiol. Rev. 84, 835-867
2. Bowery, N. G., Bettler, B., Froestl, W., Gallagher, J. P., Marshall, F., Raiteri, M., Bonner, T. I., and Enna, S. J. (2002) Pharmacol. Rev. 54, 247-264
3. Couve, A., Moss, S. J., and Pangalos, M. N. (2000) Mol. Cell. Neurosci. 16, 296-312
4. Dunlap, K., and Fischbach, G. D. (1981) J. Physiol. (Lond.) 317, 519-535
5. Jarolimek, W., and Misgeld, U. (1997) J. Neurosci. 17, 1025-1032
6. Sakaba, T., and Neher, E. (2003) Nature 424, 775-778
7. Scanziani, M., Capogna, M., Gahwiler, B. H., and Thompson, S. M. (1992) Neuron 9, 919-927
8. Yamada, J., Saitow, F., Satake, S., Kiyohara, T., and Konishi, S. (1999) Neuropharmacology 38, 1743-1753
9. Lüscher, C., Jan, L. Y., Stoffel, M., Malenka, R. C., and Nicoll, R. A. (1997) Neuron 19, 687-695
10. Marshall, F. H., Jones, K. A., Kaupmann, K., and Bettler, B. (1999) Trends Pharmacol. Sci. 20, 396-399
11. Schuler, V., Lüscher, C., Blanchet, C., Klix, N., Sansig, G., Klebs, K., Schmutz, M., Heid, J., Gentry, C., Urban, L., Fox, A., Spooren, W., Jaton, A. L., Vigouret, J. M., Pozza, M., Kelly, P. H., Mosbacher, J., Froestl, W., Käslin, E., Korn, R., Bischoff, S., Kaupmann, K., van der Putten, H., and Bettler, B. (2001) Neuron 31, 47-58
12. Gassmann, M., Shaban, H., Vigot, R., Sansig, G., Haller, C., Barbieri, S., Humeau, Y., Schuler, V., Muller, M., Kinzel, B., Klebs, K., Schmutz, M., Froestl, W., Heid, J., Kelly, P. H., Gentry, C., Jaton, A. L., Van der Putten, H., Mombereau, C., Lecourtier, L., Mosbacher, J., Cryan, J. F., Fritschy, J. M., Luthi, A., Kaupmann, K., and Bettler, B. (2004) J. Neurosci. 24, 6086-6097
13. Prosser, H. M., Gill, C. H., Hirst, W. D., Grau, E., Robbins, M., Calver, A., Soffin, E. M., Farmer, C. E., Lanneau, C., Gray, J., Schenck, E., Warmerdam, B. S., Clapham, C., Reavill, C., Rogers, D. C., Stean, T., Upton, N., Humphreys, K., Randall, A., Geppert, M., Davies, C. H., and Pangalos, M. N. (2001) Mol. Cell. Neurosci. 17, 1059-1070
14. Holter, J., Davies, J., Leresche, N., Crunelli, V., and Carter, D. A. (2005) J. Mol. Neurosci. 26, 99-108
15. Schwarz, D. A., Barry, G., Eliasof, S. D., Petroski, R. E., Conlon, P. J., and Maki, R. A. (2000) J. Biol. Chem. 275, 32174-32181
16. Wei, K., Jia, Z., Wang, Y. T., Yang, J., Liu, C. C., and Snead, O. C., III (2001) Brain Res. Mol. Brain Res. 89, 103-110
17. Steiger, J. L., Bandyopadhyay, S., Farb, D. H., and Russek, S. J. (2004) J. Neurosci. 24, 6115-6126
18. Hawrot, E., Xiao, Y., Shi, Q. L., Norman, D., Kirkitadze, M., and Barlow, P. N. (1998) FEBS Lett. 432, 103-108
19. Blein, S., Ginham, R., Uhrin, D., Smith, B. O., Soares, D. C., Veltel, S., McIlhinney, R. A., White, J. H., and Barlow, P. N. (2004) J. Biol. Chem. 279, 48292-48306
20. Soares, D. C., and Barlow, P. N. (2005) in Structural Biology of the Complement System (Morikis, D., and Lambris, J. D., eds) pp. 19-62, CRC Press, Taylor and Francis Group, Boca Raton
21. Grace, C. R., Perrin, M. H., DiGruccio, M. R., Miller, C. L., Rivier, J. E., Vale, W. W., and Riek, R. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 12836-12841
22. Vigot, R., Barbieri, S., Brauner-Osborne, H., Turecek, R., Shigemoto, R., Zhang, Y. P., Lujan, R., Jacobson, L. H., Biermann, B., Fritschy, J. M., Vacher, C. M., Muller, M., Sansig, G., Guetg, N., Cryan, J. F., Kaupmann, K., Gassmann, M., Oertner, T. G., and Bettler, B. (2006) Neuron 50, 589-601
23. Shaban, H., Humeau, Y., Herry, C., Cassasus, G., Shigemoto, R., Ciocchi, S., Barbieri, S., van der Putten, H., Kaupmann, K., Bettler, B., and Luthi, A. (2006) Nat. Neurosci. 9, 1028-1035
24. Ulrich, D., and Bettler, B. (2007) Curr. Opin. Neurobiol. 17, 298-303
25. Bulanova, E., Budagian, V., Duitman, E., Orinska, Z., Krause, H., Ruckert, R., Reiling, N., and Bulfone-Paus, S. (2007) J. Biol. Chem. 282, 13167-13179
26. Mosley, B., Beckmann, M. P., March, C. J., Idzerda, R. L., Gimpel, S. D., VandenBos, T., Friend, D., Alpert, A., Anderson, D., Jackson, J., Wignall, J. M., Smith, C., Gallis, B., Sims, J. E., Urdal, D., Widmer, M. B., Cosman, D., and Park, L. (1989) Cell 59, 335-348
27. Kaupmann, K., Huggel, K., Heid, J., Flor, P. J., Bischoff, S., Mickel, S. J., McMaster, G., Angst, C., Bittiger, H., Froestl, W., and Bettler, B. (1997) Nature 386, 239-246
28. Schaeren-Wiemers, N., and Gerfin-Moser, A. (1993) Histochemistry 100, 431-440
29. Pagano, A., Rovelli, G., Mosbacher, J., Lohmann, T., Duthey, B., Stauffer, D., Ristig, D., Schuler, V., Meigel, I., Lampert, C., Stein, T., Prezeau, L., Blahos, J., Pin, J., Froestl, W., Kuhn, R., Heid, J., Kaupmann, K., and Bettler, B. (2001) J. Neurosci. 21, 1189-1202
30. Rolink, A. G., Andersson, J., and Melchers, F. (1998) Eur. J. Immunol. 28, 3738-3748
31. Goslin, K., Asmussen, H., and Banker, G. (1998) in Culturing Nerve Cells (Banker, G., and Goslin, K., eds) pp. 339-370, MIT Press, Cambridge, MA
32. Bischoff, S., Leonhard, S., Reymann, N., Schuler, V., Shigemoto, R., Kaupmann, K., and Bettler, B. (1999) J. Comp. Neurol. 412, 1-16
33. Lei, S., and McBain, C. J. (2003) J. Physiol. (Lond.) 546, 439-453
34. Dunlap, K. (1981) Br. J. Pharmacol. 74, 579-585
35. Saglietti, L., Dequidt, C., Kamieniarz, K., Rousset, M. C., Valnegri, P., Thoumine, O., Beretta, F., Fagni, L., Choquet, D., Sala, C., Sheng, M., and Passafaro, M. (2007) Neuron 54, 461-477
36. Sia, G. M., Beique, J. C., Rumbaugh, G., Cho, R., Worley, P. F., and Huganir, R. L. (2007) Neuron 55, 87-102
37. Gally, C., Eimer, S., Richmond, J. E., and Bessereau, J. L. (2004) Nature 431, 578-582
38. Fairfax, B. P., Pitcher, J. A., Scott, M. G., Calver, A. R., Pangalos, M. N., Moss, S. J., and Couve, A. (2004) J. Biol. Chem. 279, 12565-12573
39. Froestl, W., Gallagher, M., Jenkins, H., Madrid, A., Melcher, T., Teichman, S., Mondadori, C. G., and Pearlman, R. (2004) Biochem. Pharmacol. 68, 1479-1487